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Gene Dmel\Aats-asn

General Information
Symbol	Dmel\Aats-asn	Species	D. melanogaster
Name	Asparaginyl-tRNA synthetase	Annotation symbol	CG10687
Feature type	protein_coding_gene	FlyBase ID	FBgn0086443
Gene Model Status	Current	Stock availability	12 publicly available
Also Known As	l(2)37Ca, Ca
Genomic Location
Chromosome (arm)	2L	Recombination map	2-53.9+
Cytogenetic map	37C5-37C5	Sequence location	2L:19,129,862..19,131,960 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Asparaginyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-asn (CG10687, FBgn0086443). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: asparagine-tRNA ligase activity. It is reported to be involved in the biological process: asparaginyl-tRNA aminoacylation. 53 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; adult head; metathoracic bristle; scutellar bristle; wing; mesothoracic bristle. It has one annotated transcript and one annotated polypeptide. Protein features are: Aminoacyl-tRNA synthetase, class II; Aminoacyl-tRNA synthetase, class II (D/K/N); Aminoacyl-tRNA synthetase, class II (D/K/N)-like; Asparaginyl-tRNA synthetase, class IIb; Aspartyl/Asparaginyl-tRNA synthetase, class IIb; Nucleic acid binding, OB-fold, tRNA/helicase-type; Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, larval/adult salivary gland, adult ovary, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult spermathecae, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1624475_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Aats-asn. Gene sequence location is 2L:19129862..19131960.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	l(2)37Ca l(2)37Cats1/Df(2L)TW130 eclosed adults at 25 have incompletely sclerotized thoracic cuticle, which deforms when the indirect flight muscles contract; wings rarely completely expanded. X-ray-induced abdominal clones hemizygous for the amorphic allele l(2)37Ca4, produce bristles one-third wildtype size.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10	Controlled Vocabulary Terms day 6 of adulthood day 5 of adulthood male day 7 of adulthood spermatozoon
FB2012_01	Sequence features BKN20336 HFA01990
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 37C5-37C5   Left limit from inclusion within Df(2L)VA21 (FBrf0084402) Right limit from non-inclusion within Df(2L)VA12 (FBrf0035993)
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	2-53.9+
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Aats-asn for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Aats-asn-RA FBtr0081162  NM_136104   1988   558
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Aats-asn-PA   FBpp0080705   63.9   558   5.76     NP_609948   AAF53768
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Aminoacyl-tRNA synthetase, class II (D/K/N)-like (IPR018150) Nucleic acid-binding, OB-fold (IPR012340) Aminoacyl-tRNA synthetase, class II (IPR006195) Asparaginyl-tRNA synthetase, class IIb (IPR004522) Nucleic acid binding, OB-fold, tRNA/helicase-type (IPR004365) Aminoacyl-tRNA synthetase, class II (D/K/N) (IPR004364) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (IPR002312) Nucleic acid-binding, OB-fold-like (IPR016027)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA390602   AA392700   AA539437   AA695878   AA696913   AA699034   AA802050   AA802129   AA802609   AE014134 AAF53768   AF181634 AAD55420   AI107139   AI387441   AI402048   AI454957   AI543477   AI543708   AY433313   BF500123   BF503958   BG639723   BI171596   BI216544   BI216572   BI237890   BI355124   BI361978   BI365664   BI370937   BI370994   BI373461   BI374543   BI482065   BI482620   BI485410   BI486379   BI563723   BI563751   BI565061   BI569057   BI569058   BI569544   BI570144   BI574910   BI577792   BI578006   BI578116   BI579747   BI583492   BI585134   BI587057   BI590093   BI592045   BI615494   BI621062   BI623582   BI624621   BI625114   BI626711   BI630423   BI635447   BI636514   BX021132   BX044737   BX044869   CO178677   CO281026   CO285325   CO300904   CO336355   CO340843   EC085542   EC211281   EC218635   EC236075   EC245023   EC245975   EC258210   EC264186   ES696446   FE863513   FE863588   FE863643   FE863668   FE863719   FE863773   FE863832   GH740034   GH741720   GH743380   GH762220   GH764393   GH766650
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V434
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism | ubiquitous   (Seshaiah and Andrew, 1999) embryonic/larval salivary gland   (Seshaiah and Andrew, 1999)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0086443    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0086443 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0086443 expression level Developmental Stage   Expression Level embryo 00-02hr    8495 embryo 02-04hr    3439 embryo 04-06hr    2032 embryo 06-08hr    2837 embryo 08-10hr    3708 embryo 10-12hr    6779 embryo 12-14hr    4181 embryo 14-16hr    4872 embryo 16-18hr    3623 embryo 18-20hr    2859 embryo 20-22hr    2904 embryo 22-24hr    2674 larva L1    7682 larva L2    7775 larva L3 12hr old    6110 larva L3 puffstage 1-2    3985 larva L3 puffstage 3-6    4221 larva L3 puffstage 7-9    4406 white prepupae new    4319 white prepupae 12hr    3557 white prepupae 24hr    4143 pupae 2d postWPP    3296 pupae 3d postWPP    2521 pupae 4d postWPP    2377 adult male 01day    2555 adult male 05day    2845 adult male 30day    3032 adult female 01day    7621 adult female 05day    8957 adult female 30day    8993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (8495) embryo 02-04hr  (3439) embryo 04-06hr  (2032) embryo 06-08hr  (2837) embryo 08-10hr  (3708) embryo 10-12hr  (6779) embryo 12-14hr  (4181) embryo 14-16hr  (4872) embryo 16-18hr  (3623) embryo 18-20hr  (2859) embryo 20-22hr  (2904) embryo 22-24hr  (2674) larva L1  (7682) larva L2  (7775) larva L3 12hr old  (6110) larva L3 puffstage 1-2  (3985) larva L3 puffstage 3-6  (4221) larva L3 puffstage 7-9  (4406) white prepupae new  (4319) white prepupae 12hr  (3557) white prepupae 24hr  (4143) pupae 2d postWPP  (3296) pupae 3d postWPP  (2521) pupae 4d postWPP  (2377) adult male 01day  (2555) adult male 05day  (2845) adult male 30day  (3032) adult female 01day  (7621) adult female 05day  (8957) adult female 30day  (8993) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (8495) embryo 02-04hr  (3439) embryo 04-06hr  (2032) embryo 06-08hr  (2837) embryo 08-10hr  (3708) embryo 10-12hr  (6779) embryo 12-14hr  (4181) embryo 14-16hr  (4872) embryo 16-18hr  (3623) embryo 18-20hr  (2859) embryo 20-22hr  (2904) embryo 22-24hr  (2674) larva L1  (7682) larva L2  (7775) larva L3 12hr old  (6110) larva L3 puffstage 1-2  (3985) larva L3 puffstage 3-6  (4221) larva L3 puffstage 7-9  (4406) white prepupae new  (4319) white prepupae 12hr  (3557) white prepupae 24hr  (4143) pupae 2d postWPP  (3296) pupae 3d postWPP  (2521) pupae 4d postWPP  (2377) adult male 01day  (2555) adult male 05day  (2845) adult male 30day  (3032) adult female 01day  (7621) adult female 05day  (8957) adult female 30day  (8993) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8495 embryo 02-04hr    3439 embryo 04-06hr    2032 embryo 06-08hr    2837 embryo 08-10hr    3708 embryo 10-12hr    6779 embryo 12-14hr    4181 embryo 14-16hr    4872 embryo 16-18hr    3623 embryo 18-20hr    2859 embryo 20-22hr    2904 embryo 22-24hr    2674 larva L1    7682 larva L2    7775 larva L3 12hr old    6110 larva L3 puffstage 1-2    3985 larva L3 puffstage 3-6    4221 larva L3 puffstage 7-9    4406 white prepupae new    4319 white prepupae 12hr    3557 white prepupae 24hr    4143 pupae 2d postWPP    3296 pupae 3d postWPP    2521 pupae 4d postWPP    2377 adult male 01day    2555 adult male 05day    2845 adult male 30day    3032 adult female 01day    7621 adult female 05day    8957 adult female 30day    8993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8495 embryo 02-04hr    3439 embryo 04-06hr    2032 embryo 06-08hr    2837 embryo 08-10hr    3708 embryo 10-12hr    6779 embryo 12-14hr    4181 embryo 14-16hr    4872 embryo 16-18hr    3623 embryo 18-20hr    2859 embryo 20-22hr    2904 embryo 22-24hr    2674 larva L1    7682 larva L2    7775 larva L3 12hr old    6110 larva L3 puffstage 1-2    3985 larva L3 puffstage 3-6    4221 larva L3 puffstage 7-9    4406 white prepupae new    4319 white prepupae 12hr    3557 white prepupae 24hr    4143 pupae 2d postWPP    3296 pupae 3d postWPP    2521 pupae 4d postWPP    2377 adult male 01day    2555 adult male 05day    2845 adult male 30day    3032 adult female 01day    7621 adult female 05day    8957 adult female 30day    8993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0086443 expression level Developmental Stage   Expression Level embryo 00-02hr    8495 embryo 02-04hr    3439 embryo 04-06hr    2032 embryo 06-08hr    2837 embryo 08-10hr    3708 embryo 10-12hr    6779 embryo 12-14hr    4181 embryo 14-16hr    4872 embryo 16-18hr    3623 embryo 18-20hr    2859 embryo 20-22hr    2904 embryo 22-24hr    2674 larva L1    7682 larva L2    7775 larva L3 12hr old    6110 larva L3 puffstage 1-2    3985 larva L3 puffstage 3-6    4221 larva L3 puffstage 7-9    4406 white prepupae new    4319 white prepupae 12hr    3557 white prepupae 24hr    4143 pupae 2d postWPP    3296 pupae 3d postWPP    2521 pupae 4d postWPP    2377 adult male 01day    2555 adult male 05day    2845 adult male 30day    3032 adult female 01day    7621 adult female 05day    8957 adult female 30day    8993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (8495) embryo 02-04hr  (3439) embryo 04-06hr  (2032) embryo 06-08hr  (2837) embryo 08-10hr  (3708) embryo 10-12hr  (6779) embryo 12-14hr  (4181) embryo 14-16hr  (4872) embryo 16-18hr  (3623) embryo 18-20hr  (2859) embryo 20-22hr  (2904) embryo 22-24hr  (2674) larva L1  (7682) larva L2  (7775) larva L3 12hr old  (6110) larva L3 puffstage 1-2  (3985) larva L3 puffstage 3-6  (4221) larva L3 puffstage 7-9  (4406) white prepupae new  (4319) white prepupae 12hr  (3557) white prepupae 24hr  (4143) pupae 2d postWPP  (3296) pupae 3d postWPP  (2521) pupae 4d postWPP  (2377) adult male 01day  (2555) adult male 05day  (2845) adult male 30day  (3032) adult female 01day  (7621) adult female 05day  (8957) adult female 30day  (8993) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (8495) embryo 02-04hr  (3439) embryo 04-06hr  2032 embryo 06-08hr  (2837) embryo 08-10hr  (3708) embryo 10-12hr  (6779) embryo 12-14hr  (4181) embryo 14-16hr  (4872) embryo 16-18hr  (3623) embryo 18-20hr  (2859) embryo 20-22hr  (2904) embryo 22-24hr  (2674) larva L1  (7682) larva L2  (7775) larva L3 12hr old  (6110) larva L3 puffstage 1-2  (3985) larva L3 puffstage 3-6  (4221) larva L3 puffstage 7-9  (4406) white prepupae new  (4319) white prepupae 12hr  (3557) white prepupae 24hr  (4143) pupae 2d postWPP  (3296) pupae 3d postWPP  (2521) pupae 4d postWPP  2377 adult male 01day  (2555) adult male 05day  (2845) adult male 30day  (3032) adult female 01day  (7621) adult female 05day  (8957) adult female 30day  (8993) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    8495 embryo 02-04hr    3439 embryo 04-06hr    2032 embryo 06-08hr    2837 embryo 08-10hr    3708 embryo 10-12hr    6779 embryo 12-14hr    4181 embryo 14-16hr    4872 embryo 16-18hr    3623 embryo 18-20hr    2859 embryo 20-22hr    2904 embryo 22-24hr    2674 larva L1    7682 larva L2    7775 larva L3 12hr old    6110 larva L3 puffstage 1-2    3985 larva L3 puffstage 3-6    4221 larva L3 puffstage 7-9    4406 white prepupae new    4319 white prepupae 12hr    3557 white prepupae 24hr    4143 pupae 2d postWPP    3296 pupae 3d postWPP    2521 pupae 4d postWPP    2377 adult male 01day    2555 adult male 05day    2845 adult male 30day    3032 adult female 01day    7621 adult female 05day    8957 adult female 30day    8993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    8495 embryo 02-04hr    3439 embryo 04-06hr    2032 embryo 06-08hr    2837 embryo 08-10hr    3708 embryo 10-12hr    6779 embryo 12-14hr    4181 embryo 14-16hr    4872 embryo 16-18hr    3623 embryo 18-20hr    2859 embryo 20-22hr    2904 embryo 22-24hr    2674 larva L1    7682 larva L2    7775 larva L3 12hr old    6110 larva L3 puffstage 1-2    3985 larva L3 puffstage 3-6    4221 larva L3 puffstage 7-9    4406 white prepupae new    4319 white prepupae 12hr    3557 white prepupae 24hr    4143 pupae 2d postWPP    3296 pupae 3d postWPP    2521 pupae 4d postWPP    2377 adult male 01day    2555 adult male 05day    2845 adult male 30day    3032 adult female 01day    7621 adult female 05day    8957 adult female 30day    8993 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0086443    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0086443 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, larval/adult salivary gland, adult ovary, adult male accessory gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval trachea, adult spermathecae, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0086443 expression level Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland    1049.3 Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules    547.5 Adult Fat Body    300.6 Adult Salivary Gland    538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary    519.7 Adult Testis    142.5 Adult Male Accessory Gland    552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland  (1049.3) Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules  (547.5) Adult Fat Body    300.6 Adult Salivary Gland  538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary  519.7 Adult Testis    142.5 Adult Male Accessory Gland  (552.6) Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland  1049.3 Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules    547.5 Adult Fat Body    300.6 Adult Salivary Gland    538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary    519.7 Adult Testis    142.5 Adult Male Accessory Gland    552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland    1049.3 Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules    547.5 Adult Fat Body    300.6 Adult Salivary Gland    538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary    519.7 Adult Testis    142.5 Adult Male Accessory Gland    552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0086443 expression level Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland    1049.3 Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules    547.5 Adult Fat Body    300.6 Adult Salivary Gland    538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary    519.7 Adult Testis    142.5 Adult Male Accessory Gland    552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland  (1049.3) Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules  547.5 Adult Fat Body    300.6 Adult Salivary Gland  538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary  519.7 Adult Testis    142.5 Adult Male Accessory Gland  552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland  1049.3 Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules    547.5 Adult Fat Body    300.6 Adult Salivary Gland    538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary    519.7 Adult Testis    142.5 Adult Male Accessory Gland    552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    395.425 Larval Midgut    273.1 Larval Hindgut    254 Larval Malpighian Tubules    306 Larval Fat Body    282.5 Larval Salivary Gland    1049.3 Larval Trachea    375.8 Larval Carcass    464.525 Adult Head    264.2 Adult Eye    208.825 Adult Brain    258.5 Adult Thoracic-Abdominal Ganglion    284.9 Adult Crop    347.8 Adult Midgut    441.1 Adult Hindgut    268.8 Adult Malpighian Tubules    547.5 Adult Fat Body    300.6 Adult Salivary Gland    538.2 Adult Heart    186.05 Adult VirginFemale Spermatheca    375.5 Adult InseminatedFemale Spermatheca    447.8 Adult Ovary    519.7 Adult Testis    142.5 Adult Male Accessory Gland    552.6 Adult Carcass    271.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    264.2   NA  Eye    208.825   NA  Brain    258.5   395.425  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    284.9   NA  Crop    347.8   273.1  Midgut    441.1   254  Hindgut    268.8   306  Malpighian Tubules    547.5   282.5  Fat Body    300.6   1049.3  Salivary Gland    538.2   NA  Heart    186.05   375.8  Trachea    NA   NA  VirginFemale Spermatheca    375.5   NA  InseminatedFemale Spermatheca    447.8   NA  Ovary    519.7   NA  Testis    142.5   NA  Male Accessory Gland    552.6   464.525  Carcass    271.4 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_26
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086443 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10687-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal Aats-asn39 lethal, with Scer\GAL4pnr-MD237 Aats-asnGD7064 lethal | conditional Aats-asn8 Aats-asn11 lethal | heat sensitive Aats-asnts3 lethal | larval stage Aats-asn3 Aats-asn10 Aats-asn28 lethal | larval stage | recessive Aats-asn3 lethal | recessive Aats-asn1 Aats-asn2 Aats-asn3 Other Phenotypes Allele body color defective | recessive Aats-asnts2 wild-type Aats-asn+t3.6 Aats-asn+t4.6 Aats-asn+t6.8 Phenotype manifest in Allele adult head Aats-asnts1 adult thorax Aats-asnts1 adult thorax & adult cuticle Aats-asnts2 cuticle | pharate adult stage Aats-asnts2 macrochaeta | somatic clone Aats-asn4 mesothoracic bristle Aats-asn16 Aats-asn2 Aats-asnts2 metathoracic bristle Aats-asn16 Aats-asn2 Aats-asnts2 scutellar bristle Aats-asn16 Aats-asn2 Aats-asnts2 wing Aats-asnts1 Aats-asnts2
Classical Alleles ( 45 )
For All Classical Alleles Show
Allele of Aats-asn Class Mutagen Stocks Known lesion Aats-asn1 ethyl methanesulfonate 3 -- Aats-asn4 amorphic allele - genetic evidence ethyl methanesulfonate 2 -- Aats-asn6 ethyl methanesulfonate 2 -- Aats-asn2 ethyl methanesulfonate 1 -- Aats-asn39 ethyl methanesulfonate gamma ray 1 -- Aats-asnG2262 P-element activity 1 -- Aats-asn3 amorphic allele - genetic evidence ethyl methanesulfonate 0 -- Aats-asnts2 amorphic allele - genetic evidence ethyl methanesulfonate gamma ray 0 -- Aats-asn10 ethyl methanesulfonate 0 -- Aats-asn11 ethyl methanesulfonate 0 -- Aats-asn12 ethyl methanesulfonate 0 -- Aats-asn13 ethyl methanesulfonate 0 -- Aats-asn14 ethyl methanesulfonate formaldehyde 0 -- Aats-asn15 ethyl methanesulfonate formaldehyde 0 -- Aats-asn16 ethyl methanesulfonate formaldehyde 0 -- Aats-asn17 ethyl methanesulfonate formaldehyde 0 -- Aats-asn18 ethyl methanesulfonate formaldehyde 0 -- Aats-asn19 ethyl methanesulfonate formaldehyde 0 -- Aats-asn20 ethyl methanesulfonate formaldehyde 0 -- Aats-asn21 ethyl methanesulfonate formaldehyde 0 -- Aats-asn22 ethyl methanesulfonate formaldehyde 0 -- Aats-asn23 ethyl methanesulfonate formaldehyde 0 -- Aats-asn24 ethyl methanesulfonate formaldehyde 0 -- Aats-asn25 ethyl methanesulfonate 0 -- Aats-asn26 ethyl methanesulfonate 0 -- Aats-asn27 ethyl methanesulfonate 0 -- Aats-asn28 ethyl methanesulfonate 0 -- Aats-asn29 ethyl methanesulfonate 0 -- Aats-asn30 ethyl methanesulfonate 0 -- Aats-asn31 ethyl methanesulfonate 0 -- Aats-asn32 ethyl methanesulfonate gamma ray 0 -- Aats-asn33 ethyl methanesulfonate gamma ray 0 -- Aats-asn34 ethyl methanesulfonate gamma ray 0 -- Aats-asn35 ethyl methanesulfonate 0 -- Aats-asn36 gamma ray 0 -- Aats-asn37 ethyl methanesulfonate 0 -- Aats-asn38 ethyl methanesulfonate 0 -- Aats-asn40 ethyl methanesulfonate gamma ray 0 -- Aats-asn41 ethyl methanesulfonate gamma ray 0 -- Aats-asn5 ethyl methanesulfonate 0 -- Aats-asn7 ethyl methanesulfonate 0 -- Aats-asn8 ethyl methanesulfonate 0 -- Aats-asn9 ethyl methanesulfonate 0 -- Aats-asnts1 ethyl methanesulfonate 0 -- Aats-asnts3 ethyl methanesulfonate formaldehyde 0 --
Alleles Carried on Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Aats-asn Class Mutagen Stocks Known lesion Aats-asnGD7064 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes Aats-asnJF02948 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Aats-asnKK100240 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Aats-asn+t3.6 in vitro construct - genomic fragment 0 Yes Aats-asn+t4.6 in vitro construct - genomic fragment 0 Yes Aats-asn+t6.8 in vitro construct - genomic fragment 0 Yes Aats-asnC12 in vitro construct - genomic fragment 0 Yes Aats-asnC13 in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)E71 (Wright et al., 1981) Df(2L)Exel6042 (Ryder, 2004.4.26) Df(2L)Exel8040 (Ryder, 2004.4.26) Df(2L)NST (Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)TW50 (Wright et al., 1976) Df(2L)TW130 (Wright et al., 1976, Wright et al., 1981, Gilbert et al., 1984, Stathakis et al., 1995, Wright, 1996) Df(2L)VA17 (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)VA21 (Stathakis et al., 1995, Wright, 1996) Df(2L)VA23 (Stathakis et al., 1995)
Not disrupted in	Df(2L)E55 (Stathakis et al., 1995) Df(2L)hk18 (Gilbert et al., 1984, Pentz et al., 1986, Wright, 1996) Df(2L)hk-UC1 (Stathakis et al., 1995, Wright, 1996) Df(2L)hk-UC2 (Stathakis et al., 1995, Wright, 1996) Df(2L)OD15 (Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)Sd37 (Stathakis et al., 1995, Wright, 1996) Df(2L)Sd57 (Stathakis et al., 1995, Wright, 1996) Df(2L)Sd77 (Stathakis et al., 1995, Wright, 1996) Df(2L)TE37C-1 (Wright et al., 1981, Wright, 1996) Df(2L)TE37C-7 (Stathakis et al., 1995, Wright, 1996) Df(2L)TW137 (Stathakis et al., 1995) Df(2L)TW203 (Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)VA12 (Wright et al., 1981, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)VA13 (Wright et al., 1981, Wright, 1996) Df(2L)VA18 (Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) Df(2L)VA19 (Stathakis et al., 1995, Wright, 1996)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7064} NA P{KK100240} NA P{TRiP.JF02948} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}Aats-asnG2262 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
asparagine-tRNA ligase activity inferred from sequence or structural similarity with EMBL:D84273 AND non-traceable author statement (FlyBase, 1992-) ATP binding inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004522, InterPro:IPR006195, InterPro:IPR018150 (FlyBase Curators et al., 2004-) nucleic acid binding inferred from electronic annotation with InterPro:IPR004365 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
asparaginyl-tRNA aminoacylation inferred from electronic annotation with InterPro:IPR004522 (FlyBase Curators et al., 2004-) non-traceable author statement (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytoplasm inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004522, InterPro:IPR006195, InterPro:IPR018150 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Aats-asn allele Gene References unspecified Ddc
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61178 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0086443 DroID - A comprehensive database of gene and protein interactions. • FBgn0086443 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35194
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs	Dpse\GA10495
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL006577-PA Aedes aegypti (mosquito) AGAP002969-PA Anopheles gambiae (mosquito) XP_623490.1 Apis mellifera (honey bee) XP_001951757.1 Acyrthosiphon pisum (pea aphid) 9285 Batrachochytrium dendrobatidis (chytrid fungus) 245752 Branchiostoma floridae (lancelet) XP_001898693.1 Brugia malayi (roundworm nematode) BGIBMGA013133-PA Bombyx mori (silk worm) ENSBTAP00000025659 Bos taurus (bovine) CAL0004700 Candida albicans (a form of yeast) CN02755 Caenorhabditis brenneri (small nematode) CBP35099 Caenorhabditis briggsae (nematode) CE05684 Caenorhabditis elegans (worm) ENSCAFP00000000186 Canis familiaris (dog) CAGL0A02112g Candida glabrata (haploid yeast) ENSCINP00000016694 Ciona intestinalis (sea squirt) JA16932 Caenorhabditis japonica (nematode) CMM098C Cyanidioschyzon merolae (red alga) cn05136 Cryptococcus neoformans (yeast-like fungus) CPIJ015476 Culex pipens (mosquito) ENSCPOP00000011908 Cavia porcellus (guinea pig) RP12295 Caenorhabditis remanei (nematode) ENSCSAVP00000017679 Ciona savignyi (sedentary tunicate) 148401 Capitella spl (polychaete worm) DDB0231333 Dictyostelium discoideum (amoeba) DEHA2C13684g Debaryomyces Hansenii (yeast) 306578 Daphnia pulex (daphnia) ENSDARP00000081180 Danio rerio (zebra fish) ENSECAP00000014944 Equus caballus (horse) XP_651543 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000000836 Gymnopilus aculeatus (mushroom) ENSGALP00000004871 Gallus gallus (chicken) GL50803_14375 Giardia lamblia (flagellated protozoan) 108539 Hypsipyla robusta (cedar shoot borer) ENSP00000256854 Homo sapiens (human) ISCW014576-PA Ixodes scapularis (deer tick) KLLA0A08426g Kluyveromyces lactis (yeast) 200884 Lottia gigantea (owl limpet) LmjF34.2340 Leishmania major (virus) ENSMODP00000025581 Monodelphis domestica (gray opossum) ENSMMUP00000026267 Macaca mulatta (rhesus monkey) ENSMUSP00000025483 Mus musculus (house mouse) 184858 Nematostella vectensis (starlet anemone) XP_001606841.1 Nasonia vitripennis (wasp) ENSOANP00000002740 Ornithorynchus anatinus (platypus) ENSORLP00000018897 Oryzias latipes (japanese killifish) PFE0475w Plasmodium falciparum (protozoal parasite) PHUM005788-PA Pediculus humanus (human body louse) PP15731 Pristionchus pacificus (nematode) ENSPTRP00000017072 Pan troglodytes (chimpanzee) ENSRNOP00000024264 Rattus norvegicus (norway rat) YHR019C Saccharomyces cerevisiae (budding yeast) Smp_041450 Schistosoma mansoni (trematode parasite) SPBC1773.10c Schizosaccharomyces pombe (fission yeast) 38262 Trichoplax adhaerens (metazoa) TA14880 Theileria annulata (apicomplexan parasite) XP_970641.1 Tribolium castaneum (red flour beetle) Tc00.1047053506559.350 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000004742 Tetraodon nigroviridis (green spotted pufferfish) 85661.m00062 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000045103 Xenopus tropicalis (frog) YALI0E05005g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13466 LH11433 ISCW014576 FBgn0230394 FBgn0226195 FBgn0219132 FBgn0205158 FBgn0193195 FBgn0171938 JGI_V11_306578 FBgn0070552 FBgn0162868 FBgn0162853 FBgn0162432 FBgn0158720 FBgn0139976 FBgn0120956 FBgn0113825 FBgn0092231 CPIJ015476 BGIBMGA013133 ACYPI005103 GB18152 AGAP002969 AAEL006577 PB22092 PHUM114810 GLEAN_11193
Stocks & Reagents
Stocks Listed in FlyBase ( 12 )
Bloomington	28317 y1 v1; P{TRiP.JF02948}attP2 3275 rdo1 hk1 Aats-asn1 pr1/CyO 3568 Aats-asn2 rdo1 hk1 pr1/CyO 26983 w*; P{EP}Aats-asnG2262/CyO, P{sevRas1.V12}FK1 438 RpS5a2/FM6; snaSco Aats-asn4 pr1/CyO 3195 Aats-asn6 pr1/rdo1 hk1 Aats-asn1 pr1; Dp(2;1)C239/+; Dp(2;Y)H1
Kyoto	105913 RpS5a2/FM6; snaSco Aats-asn4 pr1/CyO 101395 CyO, Cy1 dplv1 pr1 cn2 / Aats-asn39 pr1 106908 Aats-asn6 pr1/rdo1 hk1 Aats-asn1 pr1; Dp(2;1)C239/+; Dp(2;Y)H1
VDRC	v103360 P{KK100240}VIE-260B v31320 w1118; P{GD7064}v31320 v31321 w1118; P{GD7064}v31321
Genomic Clones ( 1 )
	BACR48O01 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 84 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH06451
Other clones	DPiM_GH06451
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05208 AT15031 GH17970 GM03778 GM03895 GM04706 GM06003 GM08692 GM29580 HL07339 LD01323 LD09663 LD11802 LD17561 RE13408 RE23720 RE23756 RE34218 RE46424 RE51041 RE57719 RE57787 RE60747 RE62162 RE64716 RE65334 RE68729 RE69793 RE71537 RE71794 RE71925 RE73825 RH01639 RH02409 RH03661 RH09647 RH22120 RH24604 RH27325 RH27459 RH34410 RH34447 RH45157 RH52348 RH55888 RH59462 RH62720 RH64213 RH64975 RH67733 SD04870 SD10245 SD10584 SD16811 SD18218
Other clones	37552 53833 56458 78820 214281.28 557773 CK01.72B.G5 EK057327 EK155750 EK168750 EK179631 EN12350 EP11438 RH01265 RM07440 RM07540 RM07640 RM07740 RM07840 RM07940 RM08140 RP001006099 RP001015018 RP001036945 RP001038570 RP001042574 RP001050513
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0086443 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35194 49166
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Aats-asn CG10687 (FlyBase, 1996-) Source for merge of: Aats-asn l(2)37Ca (FlyBase, 1996-)
Additional comments
Other Comments
	Located between coordinates +14.0 and +16.1. (Stathakis et al., 1995) Complementation analysis of the 7.6kb PstI fragment demonstrates this fragment carries the Ddc gene alone. (Marsh et al., 1985)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136104 RefSeq (Proteins) • NP_609948 DDBJ / EMBL / GenBank • AA695878 AAD55420 AAF53768 AF181634 AI107139 AI402048 Entrez Gene - A searchable database of RefSeq genes. • 35194 UniProtKB/TrEMBL • Q9V434
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Aminoacyl-tRNA synthetase, class II (D/K/N)-like (IPR018150) Nucleic acid-binding, OB-fold (IPR012340) Aminoacyl-tRNA synthetase, class II (IPR006195) Asparaginyl-tRNA synthetase, class IIb (IPR004522) Nucleic acid binding, OB-fold, tRNA/helicase-type (IPR004365) Aminoacyl-tRNA synthetase, class II (D/K/N) (IPR004364) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (IPR002312) Nucleic acid-binding, OB-fold-like (IPR016027)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61178 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0086443 DroID - A comprehensive database of gene and protein interactions. • FBgn0086443 DRSC - Results from RNAi screens. • FBgn0086443 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086443 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10687-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0086443 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35194 49166 InParanoid A subset of ortholog calls from InParanoid. • AAEL006577-PA Aedes aegypti (mosquito) AGAP002969-PA Anopheles gambiae (mosquito) XP_623490.1 Apis mellifera (honey bee) XP_001951757.1 Acyrthosiphon pisum (pea aphid) 9285 Batrachochytrium dendrobatidis (chytrid fungus) 245752 Branchiostoma floridae (lancelet) XP_001898693.1 Brugia malayi (roundworm nematode) BGIBMGA013133-PA Bombyx mori (silk worm) ENSBTAP00000025659 Bos taurus (bovine) CAL0004700 Candida albicans (a form of yeast) CN02755 Caenorhabditis brenneri (small nematode) CBP35099 Caenorhabditis briggsae (nematode) CE05684 Caenorhabditis elegans (worm) ENSCAFP00000000186 Canis familiaris (dog) CAGL0A02112g Candida glabrata (haploid yeast) ENSCINP00000016694 Ciona intestinalis (sea squirt) JA16932 Caenorhabditis japonica (nematode) CMM098C Cyanidioschyzon merolae (red alga) cn05136 Cryptococcus neoformans (yeast-like fungus) CPIJ015476 Culex pipens (mosquito) ENSCPOP00000011908 Cavia porcellus (guinea pig) RP12295 Caenorhabditis remanei (nematode) ENSCSAVP00000017679 Ciona savignyi (sedentary tunicate) 148401 Capitella spl (polychaete worm) DDB0231333 Dictyostelium discoideum (amoeba) DEHA2C13684g Debaryomyces Hansenii (yeast) 306578 Daphnia pulex (daphnia) ENSDARP00000081180 Danio rerio (zebra fish) ENSECAP00000014944 Equus caballus (horse) XP_651543 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000000836 Gymnopilus aculeatus (mushroom) ENSGALP00000004871 Gallus gallus (chicken) GL50803_14375 Giardia lamblia (flagellated protozoan) 108539 Hypsipyla robusta (cedar shoot borer) ENSP00000256854 Homo sapiens (human) ISCW014576-PA Ixodes scapularis (deer tick) KLLA0A08426g Kluyveromyces lactis (yeast) 200884 Lottia gigantea (owl limpet) LmjF34.2340 Leishmania major (virus) ENSMODP00000025581 Monodelphis domestica (gray opossum) ENSMMUP00000026267 Macaca mulatta (rhesus monkey) ENSMUSP00000025483 Mus musculus (house mouse) 184858 Nematostella vectensis (starlet anemone) XP_001606841.1 Nasonia vitripennis (wasp) ENSOANP00000002740 Ornithorynchus anatinus (platypus) ENSORLP00000018897 Oryzias latipes (japanese killifish) PFE0475w Plasmodium falciparum (protozoal parasite) PHUM005788-PA Pediculus humanus (human body louse) PP15731 Pristionchus pacificus (nematode) ENSPTRP00000017072 Pan troglodytes (chimpanzee) ENSRNOP00000024264 Rattus norvegicus (norway rat) YHR019C Saccharomyces cerevisiae (budding yeast) Smp_041450 Schistosoma mansoni (trematode parasite) SPBC1773.10c Schizosaccharomyces pombe (fission yeast) 38262 Trichoplax adhaerens (metazoa) TA14880 Theileria annulata (apicomplexan parasite) XP_970641.1 Tribolium castaneum (red flour beetle) Tc00.1047053506559.350 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000004742 Tetraodon nigroviridis (green spotted pufferfish) 85661.m00062 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000045103 Xenopus tropicalis (frog) YALI0E05005g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35194 modMine - Data generated by the modENCODE project. • FBgn0086443 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13466 LH11433 ISCW014576 FBgn0230394 FBgn0226195 FBgn0219132 FBgn0205158 FBgn0193195 FBgn0171938 JGI_V11_306578 FBgn0070552 FBgn0162868 FBgn0162853 FBgn0162432 FBgn0158720 FBgn0139976 FBgn0120956 FBgn0113825 FBgn0092231 CPIJ015476 BGIBMGA013133 ACYPI005103 GB18152 AGAP002969 AAEL006577 PB22092 PHUM114810 GLEAN_11193
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	Aats-asn (FlyBase, 1996-, Wasbrough et al., 2010, Hazelett et al., 2009, Riedl et al., 2005) AsnRS (Seshaiah and Andrew, 1999.7.29) BcDNA:GH06451 (Giot et al., 2003, ) Ca (Wright, 1996, McCrady and Tolin, 1994) CG10687 (Gong et al., 2004, Keleman et al., 2009.8.5, Perkins et al., 2009, Riedl et al., 2005) l(2)37Ca (FlyBase, 1996-, McCrady and Tolin, 1994, Wright, 1987) l(2)37Ca)E11   l(2)E11 (Wright et al., 1976, ) NRS (Seshaiah and Andrew, 1999)
Name Synonym	Asparaginyl-tRNA synthetase (Seshaiah and Andrew, 1999) lethal (2) 37Ca
Secondary FlyBase IDs
	FBgn0002029 FBgn0027092 FBgn0028492
References ( 34 )
Generate a list of	All references relating to this gene ( 34 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 4 ) Review  ( 1 ) Personal communication to FlyBase  ( 7 ) FlyBase analysis  ( 2 ) Computer file  ( 1 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 ) Book  ( 1 )
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