• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Cpr65Ax1

General Information
Symbol	Dmel\Cpr65Ax1	Species	D. melanogaster
Name	Cuticular protein 65Ax1	Annotation symbol	CG34270
Feature type	protein_coding_gene	FlyBase ID	FBgn0086900
Gene Model Status	Current	Stock availability	None publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	65A6-65A6	Sequence location	3L:6,140,631..6,141,087 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Cuticular protein 65Ax1 is referred to in FlyBase by the symbol Dmel\Cpr65Ax1 (CG34270, FBgn0086900). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of chitin-based cuticle. The biological processes in which it is involved are not known. No alleles are reported. It has one annotated transcript and one annotated polypeptide. Protein features are: Insect cuticle protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: No FlyAtlas data available because no Affy2 ProbeSet aligns to an exon of Cpr65Ax1. Comments on Affy2 ProbeSet: No relevant information because no Affy2 ProbeSet aligns to an exon of Cpr65Ax1. Gene sequence location is 3L:6140631..6141087.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 65A6-65A6
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Cpr65Ax1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Cpr65Ax1-RA FBtr0112465  NM_001104053   389   102
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Cpr65Ax1-PA   FBpp0111379   10.7   102   4.05     NP_001097523   ABW08476
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014296 ABW08476   AY071554   BI163606   BI212238   BI364479   BI366281   BI369835   BI482077   BI487150   BI577288   BT120012   CK659983   CO271350   CO288085   CO296430   CO296912   CO300509   CO309222   CO312538   CO319981   CO320240   CO320552   CO323836   CO325060   EC060048   EC078866   EC090015   EC196176   EC201813   EC210178   EC212247   EC215963   EC235199   EC239231   EC247615   FD586106   FD586238   FD586730   FD586815   FD586929   FD587462   FD587463   GH747710   GH748881   GH749878   GH749986   GH750562   GH754680   GH754818   GH755603   GH756557   GH757119   GH770641   GH774563   GH775031   GH775520   GH775982   GH777905   GH778082   GH778416   GH781191   GH784273   GH785062   GH786504   GH787863   GH791694   GH791965   GH793947   GH794118   GH796195   GH799868   GH802139   GH802946   GH805267   GH807606   GH809688   GH810412   GH810663   GH810702   GH811457   GH812652   GH815342   GH817560   GH818568   GH819129   GH820066   GH820760   GH821748   GH826288   GH826625   GH830534   GH834964   GH842896   GH842899   GH843632   GH844117   GH846234   GH849160   GH850387   GH850548   GH852984   GH853307   GH854321   GH854530   GH863456   GH863883   GH867279   GH872104   GH873766   GH876857   GH879566   GH883838   GH886381   GH890455   GH893108   GH893116   GH894052   GH897280   GH897903   GH900991   GH901066   GH902221   GH902672   GH905199   GH906726   GH908918   GH910259   GH912198   GH913114   GH914113   GH914470   GH914630   GH916475   GH916895   GH917790   GH925095   GH928086   GH931242   GH932755   GH935447   GO271087   GO271164
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9I7C6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    0 central nervous system, larvae L3    0 central nervous system, pupae P8    0 head, virgin 1-day female    0 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    0 head, mated 4-day female    0 head, mated 20-day female    0 head, mated 1-day male    0 head, mated 4-day male    1 head, mated 20-day male    0 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    0 digestive system, 4-day adult    0 digestive system, 20-day adult    0 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    11 carcass, 1-day adult    0 carcass, 4-day adult    0 carcass, 20-day adult    0 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of no expression detected. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr    182 embryo 18-20hr    660 embryo 20-22hr    1318 embryo 22-24hr    383 larva L1    786 larva L2    62 larva L3 12hr old    2964 larva L3 puffstage 1-2    121 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr    50 white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr  (182) embryo 18-20hr  (660) embryo 20-22hr  (1318) embryo 22-24hr  (383) larva L1  (786) larva L2  (62) larva L3 12hr old  (2964) larva L3 puffstage 1-2  (121) larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr  (50) white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr  (182) embryo 18-20hr  (660) embryo 20-22hr  (1318) embryo 22-24hr  (383) larva L1  (786) larva L2    62 larva L3 12hr old  (2964) larva L3 puffstage 1-2  (121) larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr    50 white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr    182 embryo 18-20hr    660 embryo 20-22hr    1318 embryo 22-24hr    383 larva L1    786 larva L2    62 larva L3 12hr old    2964 larva L3 puffstage 1-2    121 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr    50 white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr    182 embryo 18-20hr    660 embryo 20-22hr    1318 embryo 22-24hr    383 larva L1    786 larva L2    62 larva L3 12hr old    2964 larva L3 puffstage 1-2    121 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr    50 white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr  (182) embryo 18-20hr  (660) embryo 20-22hr  (1318) embryo 22-24hr  (383) larva L1  (786) larva L2  (62) larva L3 12hr old  (2964) larva L3 puffstage 1-2  (121) larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr  (50) white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr  (182) embryo 18-20hr  (660) embryo 20-22hr  (1318) embryo 22-24hr  (383) larva L1  (786) larva L2    62 larva L3 12hr old  (2964) larva L3 puffstage 1-2  121 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr    50 white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    1 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    2 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    11 embryo 16-18hr    182 embryo 18-20hr    660 embryo 20-22hr    1318 embryo 22-24hr    383 larva L1    786 larva L2    62 larva L3 12hr old    2964 larva L3 puffstage 1-2    121 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    1 white prepupae new    0 white prepupae 12hr    50 white prepupae 24hr    1 pupae 2d postWPP    2 pupae 3d postWPP    1 pupae 4d postWPP    1 adult male 01day    0 adult male 05day    0 adult male 30day    0 adult female 01day    0 adult female 05day    0 adult female 30day    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    354 Cadmium 50 mM 6 hrs, larvae L3    927 Cadmium 50 mM 12 hrs, larvae L3    108 Cadmium 50 mM 48 hrs, 4-day adult    542 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    239 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    253 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    891 Ethanol 10% 3 hrs, larvae L3    1135 Caffeine 1.5 mg/ml 4 hrs, larvae L3    258 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    598 Rotenone 8 μg 12 hrs, larvae L3    1251 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult  (354) Cadmium 50 mM 6 hrs, larvae L3  (927) Cadmium 50 mM 12 hrs, larvae L3  (108) Cadmium 50 mM 48 hrs, 4-day adult  (542) Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3  (239) Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3  (253) Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (891) Ethanol 10% 3 hrs, larvae L3  (1135) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (258) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3  (598) Rotenone 8 μg 12 hrs, larvae L3  (1251) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult  (354) Cadmium 50 mM 6 hrs, larvae L3  (927) Cadmium 50 mM 12 hrs, larvae L3  (108) Cadmium 50 mM 48 hrs, 4-day adult  (542) Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3  (239) Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3  (253) Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (891) Ethanol 10% 3 hrs, larvae L3  (1135) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (258) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3  (598) Rotenone 8 μg 12 hrs, larvae L3  (1251) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    354 Cadmium 50 mM 6 hrs, larvae L3    927 Cadmium 50 mM 12 hrs, larvae L3    108 Cadmium 50 mM 48 hrs, 4-day adult    542 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    239 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    253 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    891 Ethanol 10% 3 hrs, larvae L3    1135 Caffeine 1.5 mg/ml 4 hrs, larvae L3    258 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    598 Rotenone 8 μg 12 hrs, larvae L3    1251 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    354 Cadmium 50 mM 6 hrs, larvae L3    927 Cadmium 50 mM 12 hrs, larvae L3    108 Cadmium 50 mM 48 hrs, 4-day adult    542 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    239 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    253 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    891 Ethanol 10% 3 hrs, larvae L3    1135 Caffeine 1.5 mg/ml 4 hrs, larvae L3    258 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    598 Rotenone 8 μg 12 hrs, larvae L3    1251 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult  (354) Cadmium 50 mM 6 hrs, larvae L3  (927) Cadmium 50 mM 12 hrs, larvae L3  (108) Cadmium 50 mM 48 hrs, 4-day adult  (542) Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3  (239) Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3  (253) Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (891) Ethanol 10% 3 hrs, larvae L3  (1135) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (258) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3  (598) Rotenone 8 μg 12 hrs, larvae L3  (1251) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult  (354) Cadmium 50 mM 6 hrs, larvae L3  (927) Cadmium 50 mM 12 hrs, larvae L3  108 Cadmium 50 mM 48 hrs, 4-day adult  (542) Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3  (239) Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3  (253) Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3  (891) Ethanol 10% 3 hrs, larvae L3  (1135) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (258) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3  (598) Rotenone 8 μg 12 hrs, larvae L3  (1251) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    0 heat shock, 4-day adult    354 Cadmium 50 mM 6 hrs, larvae L3    927 Cadmium 50 mM 12 hrs, larvae L3    108 Cadmium 50 mM 48 hrs, 4-day adult    542 Cadmium 100 mM 48 hrs, 4-day adult    2 Copper 0.5 mM 12 hrs, larvae L3    239 Copper 15 mM 48 hrs, 4-day adult    2 Zinc 5 mM 12 hrs, larvae L3    253 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    891 Ethanol 10% 3 hrs, larvae L3    1135 Caffeine 1.5 mg/ml 4 hrs, larvae L3    258 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    17 Paraquat 5 mM 48 hrs, 4-day adult    16 Paraquat 10 mM 48 hrs, 4-day adult    8 Rotenone 2 μg 12 hrs, larvae L3    598 Rotenone 8 μg 12 hrs, larvae L3    1251 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
External Data & Images
Linkouts	BDGP expression data • RE62456 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086900
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Cpr65Ax1 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Cpr65Ax1 Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
structural constituent of chitin-based cuticle inferred from sequence or structural similarity with InterPro:IPR000618 (Willis, 2007.1.3) inferred from sequence or structural similarity with Pfam:PF00379 (Willis, 2007.1.3)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene (Willis, 2007.1.3, ) protein_coding_gene (Willis, 2007.1.3, FlyBase Genome Annotators, 2007, )
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Cpr65Ax1 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0086900
Orthologs
OrthoDB Orthologs (232) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6PZJTF Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6KKX13 Arthropod inclusive ortholog search EOG63R24R Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6PZJTF)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Cpr65Ax2     Drosophila melanogaster fruit fly  Dmel\Cpr65Ax1     Drosophila simulans   Dsim\GD13145   Y Drosophila sechellia   Dsec\GM13862   Y Drosophila erecta   Dere\GG14082   Y Drosophila pseudoobscura pseudoobscura   Dpse\GA15076   Y Drosophila persimilis   Dper\GL15558   Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6KKX13)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB47906 Y Apis mellifera Western honey bee  Amel\LOC724649 Y Apis mellifera Western honey bee  Amel\CPR12 Y Apis mellifera Western honey bee  Amel\GB46298 Y Apis mellifera Western honey bee  Amel\GB52161 Y Apis mellifera Western honey bee  Amel\CPR13 Y Apis mellifera Western honey bee  Amel\GB47903 Y Apis mellifera Western honey bee  Amel\GB42612 Y Apis mellifera Western honey bee  Amel\GB43670 Y Apis mellifera Western honey bee  Amel\GB46297 Y Apis mellifera Western honey bee  Amel\GB47902 Y Apis mellifera Western honey bee  Amel\GB46312 Y Apis mellifera Western honey bee  Amel\GB46299 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006503 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006859 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005393 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006863 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013411 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013416 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006864 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010389 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010007 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006867 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG016022 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013414 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013417 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007522 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006861 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG010008 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006862 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013413 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22753 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22751 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17027 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17029 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21414 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH19798 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22756 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17028 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22755 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21415 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21416 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22752 Y Atta cephalotes Leafcutter ant  Acep\ACEP25267 Y Atta cephalotes Leafcutter ant  Acep\ACEP27437 Y Atta cephalotes Leafcutter ant  Acep\ACEP24251 Y Atta cephalotes Leafcutter ant  Acep\ACEP17449 Y Atta cephalotes Leafcutter ant  Acep\ACEP27431 Y Atta cephalotes Leafcutter ant  Acep\ACEP25266 Y Atta cephalotes Leafcutter ant  Acep\ACEP24250 Y Atta cephalotes Leafcutter ant  Acep\ACEP27444 Y Atta cephalotes Leafcutter ant  Acep\ACEP27432 Y Atta cephalotes Leafcutter ant  Acep\ACEP25277 Y Atta cephalotes Leafcutter ant  Acep\ACEP24236 Y Atta cephalotes Leafcutter ant  Acep\ACEP25265 Y Atta cephalotes Leafcutter ant  Acep\ACEP27427 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21033 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14804 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21024 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21020 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20940 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO15374 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20939 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21032 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21025 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20958 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21019 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21021 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14803 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO14802 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21887 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21889 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20594 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20587 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19362 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20586 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19363 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20593 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20772 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19364 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21888 Y Linepithema humile Argentine ant  Lhum\LH23807 Y Linepithema humile Argentine ant  Lhum\LH19211 Y Linepithema humile Argentine ant  Lhum\LH16388 Y Linepithema humile Argentine ant  Lhum\LH16391 Y Linepithema humile Argentine ant  Lhum\LH19218 Y Linepithema humile Argentine ant  Lhum\LH16383 Y Linepithema humile Argentine ant  Lhum\LH10870 Y Linepithema humile Argentine ant  Lhum\LH24581 Y Linepithema humile Argentine ant  Lhum\LH24582 Y Linepithema humile Argentine ant  Lhum\LH16382 Y Linepithema humile Argentine ant  Lhum\LH24583 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20785 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14690 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB18423 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14691 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB18425 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14673 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20784 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14688 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20800 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB24199 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB14682 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB20794 Y Solenopsis invicta Red fire ant  Sinv\SINV25632 Y Solenopsis invicta Red fire ant  Sinv\SINV21745 Y Solenopsis invicta Red fire ant  Sinv\SINV21730 Y Solenopsis invicta Red fire ant  Sinv\SINV25026 Y Solenopsis invicta Red fire ant  Sinv\SINV16553 Y Solenopsis invicta Red fire ant  Sinv\SINV21768 Y Solenopsis invicta Red fire ant  Sinv\SINV25020 Y Solenopsis invicta Red fire ant  Sinv\SINV25023 Y Solenopsis invicta Red fire ant  Sinv\SINV16530 Y Solenopsis invicta Red fire ant  Sinv\SINV21761 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI009006 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI066082 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI003649 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001610 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI005591 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001775 Y Bombyx mori Silkmoth  Bmor\BmorCPR23 Y Bombyx mori Silkmoth  Bmor\BmorCPR39 Y Bombyx mori Silkmoth  Bmor\BmorCPR6 Y Bombyx mori Silkmoth  Bmor\BmorCPR33 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000340 Y Bombyx mori Silkmoth  Bmor\BmorCPR26 Y Bombyx mori Silkmoth  Bmor\BmorCPR37 Y Bombyx mori Silkmoth  Bmor\BGIBMGA007015 Y Bombyx mori Silkmoth  Bmor\BmorCPR7 Y Bombyx mori Silkmoth  Bmor\BmorCPR24 Y Bombyx mori Silkmoth  Bmor\BmorCPR4 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000341 Y Bombyx mori Silkmoth  Bmor\BmorCPR34 Y Bombyx mori Silkmoth  Bmor\BmorCPR27 Y Bombyx mori Silkmoth  Bmor\BmorCPR18 Y Bombyx mori Silkmoth  Bmor\BGIBMGA002549 Y Bombyx mori Silkmoth  Bmor\BmorCPR38 Y Bombyx mori Silkmoth  Bmor\BmorCPR43 Y Bombyx mori Silkmoth  Bmor\BmorCPR42 Y Bombyx mori Silkmoth  Bmor\BmorCPR32 Y Bombyx mori Silkmoth  Bmor\BmorCPR49 Y Bombyx mori Silkmoth  Bmor\BmorCPR13 Y Bombyx mori Silkmoth  Bmor\BmorCPR9 Y Bombyx mori Silkmoth  Bmor\BGIBMGA005277 Y Bombyx mori Silkmoth  Bmor\BmorCPR19 Y Pediculus humanus Human body louse  Phum\PHUM392770 Y Pediculus humanus Human body louse  Phum\PHUM605650 Y Pediculus humanus Human body louse  Phum\PHUM392750 Y Pediculus humanus Human body louse  Phum\PHUM605980 Y Pediculus humanus Human body louse  Phum\PHUM601840 Y Pediculus humanus Human body louse  Phum\PHUM606390 Y Pediculus humanus Human body louse  Phum\PHUM392730 Y Tribolium castaneum Red flour beetle  Tcas\TC013127 Y Tribolium castaneum Red flour beetle  Tcas\TC014500 Y Tribolium castaneum Red flour beetle  Tcas\TC014499 Y Tribolium castaneum Red flour beetle  Tcas\TC013131 Y Tribolium castaneum Red flour beetle  Tcas\TC014685 Y Tribolium castaneum Red flour beetle  Tcas\TC003831 Y Tribolium castaneum Red flour beetle  Tcas\TC013307 Y Tribolium castaneum Red flour beetle  Tcas\TC003834 Y Tribolium castaneum Red flour beetle  Tcas\TC013129 Y Tribolium castaneum Red flour beetle  Tcas\TC003832 Y Tribolium castaneum Red flour beetle  Tcas\TC014497 Y Tribolium castaneum Red flour beetle  Tcas\TC014770 Y Tribolium castaneum Red flour beetle  Tcas\TC013139 Y Tribolium castaneum Red flour beetle  Tcas\TC014771 Y Tribolium castaneum Red flour beetle  Tcas\TC013128 Y Tribolium castaneum Red flour beetle  Tcas\TC014498 Y Tribolium castaneum Red flour beetle  Tcas\TC014686 Y Tribolium castaneum Red flour beetle  Tcas\TC003830 Y Tribolium castaneum Red flour beetle  Tcas\TC003835 Y Tribolium castaneum Red flour beetle  Tcas\TC013138 Y Tribolium castaneum Red flour beetle  Tcas\TC004547 Y Tribolium castaneum Red flour beetle  Tcas\TC013130 Y Tribolium castaneum Red flour beetle  Tcas\TC013135 Y Tribolium castaneum Red flour beetle  Tcas\TC014720 Y Tribolium castaneum Red flour beetle  Tcas\TC002595 Y Tribolium castaneum Red flour beetle  Tcas\TC013126 Y Tribolium castaneum Red flour beetle  Tcas\TC004548 Y
Orthologs in non-Insect Arthropods (EOG63R24R)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\Map1d Y Daphnia pulex Water flea  Dpux\JGI_V11_253508 Y Daphnia pulex Water flea  Dpux\JGI_V11_58106 Y Daphnia pulex Water flea  Dpux\JGI_V11_263371 Y Daphnia pulex Water flea  Dpux\EF-1 alpha Y Daphnia pulex Water flea  Dpux\Psma3 Y Daphnia pulex Water flea  Dpux\MESK4 Y Daphnia pulex Water flea  Dpux\JGI_V11_60605 Y Daphnia pulex Water flea  Dpux\JGI_V11_303748 Y Daphnia pulex Water flea  Dpux\ycf9 Y Daphnia pulex Water flea  Dpux\Nktr Y Daphnia pulex Water flea  Dpux\JGI_V11_60650 Y Daphnia pulex Water flea  Dpux\JGI_V11_302740 Y Daphnia pulex Water flea  Dpux\JGI_V11_325416 Y Daphnia pulex Water flea  Dpux\PB2 Y Daphnia pulex Water flea  Dpux\JGI_V11_229448 Y Daphnia pulex Water flea  Dpux\JGI_V11_263370 Y Daphnia pulex Water flea  Dpux\JGI_V11_303733 Y Daphnia pulex Water flea  Dpux\JGI_V11_332302 Y Daphnia pulex Water flea  Dpux\JGI_V11_224365 Y Daphnia pulex Water flea  Dpux\JGI_V11_301237 Y Daphnia pulex Water flea  Dpux\Wbp4 Y Daphnia pulex Water flea  Dpux\JGI_V11_229447 Y Daphnia pulex Water flea  Dpux\CLDN25 Y Daphnia pulex Water flea  Dpux\ND1 Y Daphnia pulex Water flea  Dpux\JGI_V11_302183 Y Daphnia pulex Water flea  Dpux\JGI_V11_110014 Y Daphnia pulex Water flea  Dpux\mp20 Y Daphnia pulex Water flea  Dpux\JGI_V11_325539 Y Daphnia pulex Water flea  Dpux\JGI_V11_302739 Y Daphnia pulex Water flea  Dpux\JGI_V11_219079 Y Daphnia pulex Water flea  Dpux\Prc1 Y Daphnia pulex Water flea  Dpux\JGI_V11_109945 Y Daphnia pulex Water flea  Dpux\PB1-F2 Y Daphnia pulex Water flea  Dpux\JGI_V11_64995 Y Daphnia pulex Water flea  Dpux\JGI_V11_332314 Y Ixodes scapularis Deer tick  Isca\ISCW003132 Y Ixodes scapularis Deer tick  Isca\ISCW003791 Y Ixodes scapularis Deer tick  Isca\ISCW020944 Y Ixodes scapularis Deer tick  Isca\ISCW019775 Y Ixodes scapularis Deer tick  Isca\ISCW002954 Y Ixodes scapularis Deer tick  Isca\ISCW020943 Y Ixodes scapularis Deer tick  Isca\ISCW016302 Y Ixodes scapularis Deer tick  Isca\ISCW013798 Y Ixodes scapularis Deer tick  Isca\ISCW016310 Y Ixodes scapularis Deer tick  Isca\ISCW007107 Y
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 1 )
	BACR09G21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 140 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE62456
Other clones	RT04155
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP18167 RE03040 RE17287 RE49602 RE51785 RE56148 RE64728 RE70664 RE70949
Other clones	31680 65182 67450 80379 81839 177022 177775 180769 191128 CK01.85C.E1 CK01.167C.A10 EK067717 EK103133 EK178405 EK191633 EK195464 EK213625 EK215418 EK229224 EK260709 EK281637 EK283016 EK286056 FB59-CG34270-RA RM04229 RM04429 RM04529 RM04629 RM04729 RM04829 RM04929 RP003003497 RP003009746 RP003017649 RP003030850 RP003032163 RP003034137 RP003040227 RP003046570 RP003050818 RP003052669 RP003053329 RP003059931 RP003079857 RP003085579 RP003085891 RP003086567 RP003088544 RP003092111 RP003096634 RP003103863 RP003105273 RP003106602 RP003117730 RP003119960 RP003141753 RP003142295 RP003145148 RP003162352 RP003165153 RP003167233 RP003171335 RP003173034 RP003173981 RP003184810 RP003194734 RP003194906 RP003199222 RP003203749 RP003206495 RP003206569 RP003211792 RP003216655 RP003222220 RP003223417 RP003224840 RP003226916 RP003227515 RP003227805 RP003228567 RP003232019 RP003239770 RP003242405 RP003244558 RP003247051 RP003251927 RP003260376 RP003269453 RP003293249 RP003298140 RP003306081 RP003307962 RP003309537 RP003353456 RP003355991 RP003366556 RP003368921 RP003378058 RP003392745 RP003416908 RP003419284 RP003458895 RP003472772 RP003476495 RP003493397 RP003495379 RP003509609 RP003510967 RP003524254 RP003536229 RP003536968 RP003565088 RP003565174 RP003566033 RP003575629 RP003578960 RP003598005 RP003601797 RP003618266 RP003618335 RP003626220 RP003627995 RP003631841 RP003655561 RP003667235 RP003669780 RP003672206 RP003681914 RP003682912
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0086900 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740751
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Cpr65Ax1 CG18774 (FlyBase Genome Annotators, 2007)
Additional comments	Annotation CG18774 (which was eliminated in release 3 of the genome annotation) has been reinstated as CG34270 (which corresponds to Cpr65Ax1) in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007)
Other Comments
	New annotation (CG34270) in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007) Annotation CG18774 eliminated in release 3 of the genome annotation, October 2002. (FlyBase Genome Annotators, 2002-2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001104053 RefSeq (Proteins) • NP_001097523 DDBJ / EMBL / GenBank • ABW08476 Entrez Gene - A searchable database of RefSeq genes. • 5740751 UniProtKB/TrEMBL • Q9I7C6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Insect cuticle protein (IPR000618) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE62456
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0086900 DRSC - Results from RNAi screens. • FBgn0086900 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086900 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0086900 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740751 modMine - Data generated by the modENCODE project. • FBgn0086900
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CG18774   CG34270 (FlyBase Genome Annotators, 2007) Cpr65Ax1 (Willis, 2007.1.3, Karouzou et al., 2007, Karouzou et al., 2007, Sharma et al., 2011)
Name Synonym	CG18774   Cuticular protein 65Ax1
Secondary FlyBase IDs
	FBgn0042115 FBgn0085299
References ( 7 )
Research paper	Sharma et al., 2011, Chemosphere 82(3): 370--376 Transcriptome analysis provides insights for understanding the adverse effects of endosulfan in Drosophila melanogaster. [FBrf0212610]
Supplementary material	Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): Table S1. [FBrf0200185]
Review	Karouzou et al., 2007, Insect Biochem. Mol. Biol. 37(8): 754--760 Drosophila cuticular proteins with the R&R Consensus: annotation and classification with a new tool for discriminating RR-1 and RR-2 sequences. [FBrf0200175]
Personal communication to FlyBase	Willis, 2007.1.3, Drosophila genes that have the R&R consensus. Drosophila genes that have the R&R consensus. [FBrf0199281]
FlyBase analysis	FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]