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Gene Dmel\CG31751

General Information
Symbol	Dmel\CG31751	Species	D. melanogaster
Name		Annotation symbol	CG31751
Feature type	protein_coding_gene	FlyBase ID	FBgn0086909
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	36F10-36F11	Sequence location	2L:18,677,203..18,683,717 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG31751 (FBgn0086909). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: transferase activity, transferring phosphorus-containing groups. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aminoglycoside phosphotransferase; Protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages, during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult fat body, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1634738_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG31751. Gene sequence location is 2L:18677203..18683717.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 36F10-36F11   Limits computationally determined from genome sequence between P{EP}CG10413EP2164 and P{lacW}l(2)37Dbk16106&P{lacW}Catsupk05424
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG31751 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG31751-RA FBtr0081092  NM_165260   1991   417 CG31751-RB FBtr0081093  NM_136050   1838   417
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG31751-PA   FBpp0080642   47.5   417   5.60     NP_724122   AAF53686 CG31751-PB   FBpp0080643   47.5   417   5.60     NP_609894   AAF53688
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Aminoglycoside phosphotransferase (IPR002575) Protein kinase-like domain (IPR011009)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF53686   AE014134 AAF53688   AY075459 AAL68272   BG632781   BI172625   BI229702   BI366319   BI486246   BI486628   BI567630   BI574724   BI575800   BI583770   BI586346   BI587395   BI589309   BI624705   BI626785   BT133492   CK135162   CO177552   CO187304   CO194753   CO314267   CO344632   CZ485275   EC072711   EC225528   EC240915   EC253918
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VJ68 Q8SY12
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage -- adult stage     (Digilio et al., 1996)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult hindgut, larval/adult Malpighian tubules, larval/adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult fat body, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut    1540.3 Larval Malpighian Tubules    2630.1 Larval Fat Body    347.2 Larval Salivary Gland    608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut    541.7 Adult Malpighian Tubules    1236.9 Adult Fat Body    115.5 Adult Salivary Gland    1391 Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut  (1540.3) Larval Malpighian Tubules  (2630.1) Larval Fat Body    347.2 Larval Salivary Gland  (608.9) Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut  (541.7) Adult Malpighian Tubules  (1236.9) Adult Fat Body    115.5 Adult Salivary Gland  (1391) Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut  (1540.3) Larval Malpighian Tubules  (2630.1) Larval Fat Body    347.2 Larval Salivary Gland    608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut    541.7 Adult Malpighian Tubules  (1236.9) Adult Fat Body    115.5 Adult Salivary Gland  (1391) Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut    1540.3 Larval Malpighian Tubules    2630.1 Larval Fat Body    347.2 Larval Salivary Gland    608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut    541.7 Adult Malpighian Tubules    1236.9 Adult Fat Body    115.5 Adult Salivary Gland    1391 Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut    1540.3 Larval Malpighian Tubules    2630.1 Larval Fat Body    347.2 Larval Salivary Gland    608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut    541.7 Adult Malpighian Tubules    1236.9 Adult Fat Body    115.5 Adult Salivary Gland    1391 Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut  (1540.3) Larval Malpighian Tubules  (2630.1) Larval Fat Body    347.2 Larval Salivary Gland  608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut  541.7 Adult Malpighian Tubules  (1236.9) Adult Fat Body    115.5 Adult Salivary Gland  (1391) Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut  1540.3 Larval Malpighian Tubules  (2630.1) Larval Fat Body    347.2 Larval Salivary Gland    608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut    541.7 Adult Malpighian Tubules  1236.9 Adult Fat Body    115.5 Adult Salivary Gland  1391 Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    146.075 Larval Midgut    264.3 Larval Hindgut    1540.3 Larval Malpighian Tubules    2630.1 Larval Fat Body    347.2 Larval Salivary Gland    608.9 Larval Trachea    204.025 Larval Carcass    231.525 Adult Head    250.5 Adult Eye    162.775 Adult Brain    430.3 Adult Thoracic-Abdominal Ganglion    313.8 Adult Crop    102 Adult Midgut    226.5 Adult Hindgut    541.7 Adult Malpighian Tubules    1236.9 Adult Fat Body    115.5 Adult Salivary Gland    1391 Adult Heart    53.425 Adult VirginFemale Spermatheca    456.3 Adult InseminatedFemale Spermatheca    368.7 Adult Ovary    62.1 Adult Testis    77.9 Adult Male Accessory Gland    406.7 Adult Carcass    80.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    250.5   NA  Eye    162.775   NA  Brain    430.3   146.075  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    313.8   NA  Crop    102   264.3  Midgut    226.5   1540.3  Hindgut    541.7   2630.1  Malpighian Tubules    1236.9   347.2  Fat Body    115.5   608.9  Salivary Gland    1391   NA  Heart    53.425   204.025  Trachea    NA   NA  VirginFemale Spermatheca    456.3   NA  InseminatedFemale Spermatheca    368.7   NA  Ovary    62.1   NA  Testis    77.9   NA  Male Accessory Gland    406.7   231.525  Carcass    80.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male    42 head, mated 4-day male    39 head, mated 20-day male    50 salivary gland, larvae L3 wandering    30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    180 digestive system, 1-day adult    40 digestive system, 4-day adult    31 digestive system, 20-day adult    31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering    34 carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female  26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male  (42) head, mated 4-day male  (39) head, mated 20-day male  (50) salivary gland, larvae L3 wandering  (30) salivary gland, white prepupae    3 digestive system, larvae L3 wandering  (180) digestive system, 1-day adult  (40) digestive system, 4-day adult  (31) digestive system, 20-day adult  (31) fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering  (34) carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male    42 head, mated 4-day male    39 head, mated 20-day male    50 salivary gland, larvae L3 wandering    30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  (180) digestive system, 1-day adult    40 digestive system, 4-day adult    31 digestive system, 20-day adult    31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering    34 carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male    42 head, mated 4-day male    39 head, mated 20-day male    50 salivary gland, larvae L3 wandering    30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    180 digestive system, 1-day adult    40 digestive system, 4-day adult    31 digestive system, 20-day adult    31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering    34 carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male    42 head, mated 4-day male    39 head, mated 20-day male    50 salivary gland, larvae L3 wandering    30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    180 digestive system, 1-day adult    40 digestive system, 4-day adult    31 digestive system, 20-day adult    31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering    34 carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female  26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male  (42) head, mated 4-day male  (39) head, mated 20-day male  (50) salivary gland, larvae L3 wandering  30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  (180) digestive system, 1-day adult  (40) digestive system, 4-day adult  31 digestive system, 20-day adult  31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering  (34) carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male    42 head, mated 4-day male    39 head, mated 20-day male    50 salivary gland, larvae L3 wandering    30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  (180) digestive system, 1-day adult    40 digestive system, 4-day adult    31 digestive system, 20-day adult    31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering    34 carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    16 central nervous system, larvae L3    12 central nervous system, pupae P8    10 head, virgin 1-day female    26 head, virgin 4-day female    21 head, virgin 20-day female    24 head, mated 1-day female    23 head, mated 4-day female    21 head, mated 20-day female    16 head, mated 1-day male    42 head, mated 4-day male    39 head, mated 20-day male    50 salivary gland, larvae L3 wandering    30 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    180 digestive system, 1-day adult    40 digestive system, 4-day adult    31 digestive system, 20-day adult    31 fat body, larvae L3 wandering    15 fat body, white prepupae    10 fat body, pupae P8    14 carcass, larvae L3 wandering    34 carcass, 1-day adult    14 carcass, 4-day adult    11 carcass, 20-day adult    12 ovary, virgin 4-day female    7 ovary, mated 4-day female    6 testis, mated 4-day male    11 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages, during late larval stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr    57 embryo 18-20hr    46 embryo 20-22hr    19 embryo 22-24hr    30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    52 larva L3 puffstage 7-9    93 white prepupae new    65 white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr  (57) embryo 18-20hr  (46) embryo 20-22hr    19 embryo 22-24hr  (30) larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2  26 larva L3 puffstage 3-6  (52) larva L3 puffstage 7-9  (93) white prepupae new  (65) white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr    57 embryo 18-20hr    46 embryo 20-22hr    19 embryo 22-24hr    30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    52 larva L3 puffstage 7-9    93 white prepupae new    65 white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr    57 embryo 18-20hr    46 embryo 20-22hr    19 embryo 22-24hr    30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    52 larva L3 puffstage 7-9    93 white prepupae new    65 white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr    57 embryo 18-20hr    46 embryo 20-22hr    19 embryo 22-24hr    30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    52 larva L3 puffstage 7-9    93 white prepupae new    65 white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr  (57) embryo 18-20hr  (46) embryo 20-22hr    19 embryo 22-24hr  30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2  26 larva L3 puffstage 3-6  (52) larva L3 puffstage 7-9  (93) white prepupae new  (65) white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr    57 embryo 18-20hr    46 embryo 20-22hr    19 embryo 22-24hr    30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    52 larva L3 puffstage 7-9    93 white prepupae new    65 white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    9 embryo 02-04hr    4 embryo 04-06hr    6 embryo 06-08hr    9 embryo 08-10hr    12 embryo 10-12hr    15 embryo 12-14hr    24 embryo 14-16hr    21 embryo 16-18hr    57 embryo 18-20hr    46 embryo 20-22hr    19 embryo 22-24hr    30 larva L1    19 larva L2    20 larva L3 12hr old    21 larva L3 puffstage 1-2    26 larva L3 puffstage 3-6    52 larva L3 puffstage 7-9    93 white prepupae new    65 white prepupae 12hr    11 white prepupae 24hr    8 pupae 2d postWPP    9 pupae 3d postWPP    24 pupae 4d postWPP    13 adult male 01day    21 adult male 05day    19 adult male 30day    15 adult female 01day    12 adult female 05day    12 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1    38 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1  (38) embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1    38 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1    38 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1    38 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1  (38) embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1    38 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    13 Schneider line 2 Sg4    10 embryonic 1182-4H    13 embryonic GM2    5 embryonic Kc167    8 embryonic S1    38 embryonic S3    10 leg disc CME L1    11 wing disc CME-W2    15 wing disc ML-DmD8    10 wing disc ML-DmD9    15 wing disc ML-DmD16-c3    15 wing disc ML-DmD21    7 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    20 eye-antennal disc ML-DmD11    16 antennal disc ML-DmD20-c5    12 mixed discs ML-DmD4-c1    11 CNS ML-DmBG1-c1    14 CNS ML-DmBG2-c2    19 tumorous blood cells mbn2    11 ovary fGS/OSS    7 ovary OSC    9 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    59 Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3  (59) Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (44) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3  (28) Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    59 Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    59 Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    59 Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3  (59) Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (44) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3  28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    59 Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    14 cold shock, 4-day adult    15 heat shock, 4-day adult    19 Cadmium 50 mM 6 hrs, larvae L3    21 Cadmium 50 mM 12 hrs, larvae L3    59 Cadmium 50 mM 48 hrs, 4-day adult    21 Cadmium 100 mM 48 hrs, 4-day adult    9 Copper 0.5 mM 12 hrs, larvae L3    17 Copper 15 mM 48 hrs, 4-day adult    8 Zinc 5 mM 12 hrs, larvae L3    16 Zinc 4.5 mM 48 hrs, 4-day adult    14 Ethanol 2.5% 3 hrs, larvae L3    9 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    25 Caffeine 1.5 mg/ml 4 hrs, larvae L3    44 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    13 Caffeine 25 mg/ml 48 hrs, 4-day adult    13 Paraquat 5 mM 48 hrs, 4-day adult    14 Paraquat 10 mM 48 hrs, 4-day adult    16 Rotenone 2 μg 12 hrs, larvae L3    28 Rotenone 8 μg 12 hrs, larvae L3    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086909
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG31751f02725 viable, with Scer\GAL4pnr-MD237 CG31751GD10354 Sterility Allele fertile CG31751f02725 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG31751 Class Mutagen Stocks Known lesion CG31751f02725 piggyBac transposase 2 -- CG31751MB01760 1 -- CG31751MB02967 1 -- CG31751NP1565 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG31751 Class Mutagen Stocks Known lesion CG31751GD10354 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG31751KK100608 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel6041 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10354} NA P{KK100608} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{WH}CG31751f02725 NA insertion of enhancer trap binary system Mi{ET1}CG31751MB01760 No Mi{ET1}CG31751MB02967 No P{GawB}msl-1NP1565 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
transferase activity, transferring phosphorus-containing groups inferred from electronic annotation with InterPro:IPR011009 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG31751 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0086909
Orthologs
OrthoDB Orthologs (41) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6614Q0 Dipteran inclusive ortholog search EOG6V178H Insect inclusive ortholog search EOG67SR9C Arthropod inclusive ortholog search EOG6FN308 Metazoa inclusive ortholog search EOG6R2GNP
Orthologs in Drosophila Species (EOG6614Q0)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG31751     Drosophila simulans   Dsim\GD24148     Drosophila sechellia   Dsec\GM17285     Drosophila erecta   Dere\GG21124     Drosophila yakuba   Dyak\GE13198     Drosophila ananassae   Dana\GF15065     Drosophila pseudoobscura pseudoobscura   Dpse\GA16447     Drosophila persimilis   Dper\GL19628     Drosophila willistoni   Dwil\GK24686     Drosophila virilis   Dvir\GJ17679     Drosophila mojavensis   Dmoj\GI17173     Drosophila grimshawi   Dgri\GH11604
Orthologs in non-Drosophila Dipterans (EOG6V178H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003909   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL015435   Anopheles gambiae Malaria mosquito  Agam\AGAP004612   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ000646
Orthologs in non-Dipteran Insects (EOG67SR9C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40022   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007882   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH20762   Atta cephalotes Leafcutter ant  Acep\ACEP27590   Camponotus floridanus Florida carpenter ant  Cflo\CFLO15624   Linepithema humile Argentine ant  Lhum\LH14738   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20065   Solenopsis invicta Red fire ant  Sinv\SINV20618   Acyrthosiphon pisum Pea aphid  Apim\ACYPI002025   Bombyx mori Silkmoth  Bmor\BGIBMGA013816   Pediculus humanus Human body louse  Phum\PHUM372110   Tribolium castaneum Red flour beetle  Tcas\TC008884   Tribolium castaneum Red flour beetle  Tcas\TC008883
Orthologs in non-Insect Arthropods (EOG6FN308)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\COI   Ixodes scapularis Deer tick  Isca\ISCW011794
Orthologs in non-Arthropod Metazoa (EOG6R2GNP)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018524gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019627gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_007501gn   Danio rerio Zebrafish  Drer\zgc:171550   Danio rerio Zebrafish  Drer\ENSDARG00000077610   Xenopus tropicalis Western clawed frog  Xtro\agphd1   Gallus gallus Domestic chicken  Ggal\AGPHD1   Mus musculus House mouse  Mmus\Agphd1   Rattus norvegicus Norway rat  Rnor\Agphd1   Homo sapiens Human  Hsap\AGPHD1
Human Orthologs (1)
Gene OMIM HGNC Hsap\AGPHD1
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	18579 w1118; PBac{WH}CG31751f02725 23212 y1 w67c23; Mi{ET1}CG31751MB01760 23986 y1 w67c23; Mi{ET1}CG5758MB02967 Mi{ET1}CG31751MB02967
Harvard	- PBac{WH}CG31751f02725
VDRC	v21414 w1118; P{GD10354}v21414 v21415 w1118; P{GD10354}v21415
Genomic Clones ( 1 )
	BACR25C02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 25 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE15159
Other clones	FI20105
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH13786 RE27529 RE51829 RE69649 RE70078 RH22456 RH26279 RH28060 RH31712 RH32119 RH38167 RH64313 RH67839
Other clones	19153 105397 214221.38 CK01.32C.C5 EC39168 EK027911 EK053806 EK235554 EP19635 RH26548
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0086909 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35118
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG15163 CG15164 (FlyBase Genome Annotators, 2002-2003) Source for merge of: CG31751 anon-ct (FlyBase, 1996-)
Additional comments	Annotations CG15163 and CG15164 merged as CG31751 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003) Source for merge of was comparison of Figure 1. in FBrf0089631 with the corresponding region of the release 4.3 genome (date:060505). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136050 NM_165260 RefSeq (Proteins) • NP_609894 NP_724122 DDBJ / EMBL / GenBank • AAF53686 AAF53688 AAL68272 AY075459 BI172625 CZ485275 Entrez Gene - A searchable database of RefSeq genes. • 35118 UniProtKB/TrEMBL • Q8SY12 Q9VJ68
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Aminoglycoside phosphotransferase (IPR002575) Protein kinase-like domain (IPR011009)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0086909 DRSC - Results from RNAi screens. • FBgn0086909 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0086909 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0086909 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35118 modMine - Data generated by the modENCODE project. • FBgn0086909
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-ct   CG15163   CG15164   CG31751 (Vicente-Crespo et al., 2008, Keleman et al., 2009.8.5) ct (Digilio et al., 1996)
Name Synonym	constitutive transcript (Digilio et al., 1996)
Secondary FlyBase IDs
	FBgn0023099 FBgn0032696 FBgn0032697 FBgn0051751
References ( 18 )
Research paper	Vicente-Crespo et al., 2008, PLoS ONE 3(2): e1613 Drosophila muscleblind is involved in troponin T alternative splicing and apoptosis. [FBrf0210274] Digilio et al., 1996, Dev. Biol. 178(1): 90--100 Tosca: A Drosophila gene encoding a nuclease specifically expressed in the female germline. [FBrf0089631]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Bellen, 2007.2.1, Batch706FlyBase_cyto_update.xml Batch706FlyBase_cyto_update.xml [FBrf0191799] Bellen, 2007.6.19, GDPbatch746.xml GDPbatch746.xml [FBrf0199564] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. (Computer file) Genomic mapping of Exelixis insertion collection. (Computer file) [FBrf0184340] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]