pri, polished rice, MRE29, pncr001:3R
codes for short encoded peptides that convert Shavenbaby from a transcriptional repressor to an activator via the truncation of its N-terminal region, polycistronic message, epidermal differentiation, spatial pattern of trichomes, legs, trachea
See reports for tal-1A (CG42384), tal-2A (CG42385), tal-3A (CG42386) and tal-AA (CG42387).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\tal using the Feature Mapper tool.
tal expression was characterized in imaginal discs. In the eye disc, expression is observed in preclusters for presumptive R8 photoreceptors and in a stripe of cells in the posterior region of eye discs. In larval leg discs, expression is seen in a cluster of precursors that develop into stretch-sensing chordotonal organs. In early pupal leg discs, tal is expressed in the tarsal region and is concentrated at the presumptive joints between tarsal segments. In wing discs of third instar larvae, tal is present at the DV compartmental boundary and in two stripes of cells straddling the anterior part of the DV boundary that may be precursors for chemosensory organs. From late third instar to early pupal stages, tal is detected in provein cells that develop into longitudinal wing veins L2-L5.
GBrowse - Visual display of RNA-Seq signalsView Dmel\tal in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: pri tal l(3)S011041
The tal gene represents a polycistronic transcription unit that contains several non-overlapping reading frames. The annotated non-overlapping open reading frames contained within the tal transcription unit are represented by tal-1A (CG42384), tal-2A (CG42385), tal-3A (CG42386) and tal-AA (CG42387).
tal has two novel features for eukaryotic coding genes: the direct translation of short, unprocessed peptides with full biological function, and their tandem arrangement in a polycistronic messenger.
The tal genomic region contains specific regulatory sequences spread out over a minimum of 25 kb.
tal mutants are embryonic lethal. tal mutant embryos completely lack denticle belts and dorsal hairs, as well as taenidial folds in the tracheal system; localized signals of F-actin is not observed. Although small tal mutant clones show normal morphology, collapse of ommatidia is occasionally observed at the center of large clones. Mutant cells that abut wild type cells are morphologically normal, suggesting that tal functions in a non-cell autonomous fashion.
tal is required for proper embryogenesis and has an essential role in actin dynamics during denticle formation.
tal null mutants show a complete loss of denticles and a collapse of the tracheal network; denticle cells do not show the specific accumulation of F-actin required for the formation of cell protrusions.
In the leg, tal is required for the development of the whole tarsal region from tarsus one to five. The gene is not only expressed and required in the presumptive tarsal region, but also in antennae and wings, and in embryonic tissues of ectodermal origin which, undergo an invagination without losing their epithelial integrity. In the tarsus, tal controls the expression of rn and ss, and its expression is intercalated between those of B and dac.
In a mutant for tal the whole tarsal region from tarsus one to five does not develop. The phenotype is not due to cell death, but involves an alteration of the morphogenesis of the disc. tal acts in a non-autonomous manner.
New annotation (CR33327) in release 3.2 of the genome annotation.
Area matching Drosophila EST AA392324.
The gene is named "polished rice" based on the smooth cuticle phenotype of deficiencies which completely remove the transcription unit.