C96
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Gene model reviewed during 5.39
Gene model supported by FBrf0193930
Gene model reviewed during 5.46
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bbg using the Feature Mapper tool.
Comment: anlage in statu nascendi
Comment: anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage in statu nascendi
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as procephalic ectoderm anlage
Comment: reported as small intestine specific anlage
During embryogenesis, bbg transcript is predominantly expressed in the developing gut. bbg transcript is first detected at embryonic stage 5, in the posterior endoderm anlage. bbg transcript is expressed in posterior midgut primordium by stage 6, in the invaginating hindgut primordium by stage 7, in the anterior midgut primordium at stages 9-10, and in the forgut primordium by stages 11-12. Gut expression is maintained though late embryogenesis, and becomes restricted to the pharynx and proventriculus at late embryonic stages. bbg transcript expression in the dorsal ectoderm begins at embryonic stage 6; this expression is restricted to the dorsal edge of the dorsal ectoderm by embryonic stage 9-10. In the wing disc, bbg transcript is expressed at the presumptive wing margin, and in a small stripe perpendicular to the wing margin in the dorsal wing pouch. bbg transcript is expressed at the dorsal-ventral compartment boundary of the haltere disc. bbg transcript is expressed in a pair of cell clusters near the center of the leg discs; at the medial side of the antennal disc; in a ring-shaped pattern in the larval optic lobe; and at and posterior to the morphogenetic furrow of the eye disc. bbg transcript expression exhibits isoform-specificity at embryonic and larval stages.
bbg protein is localized to the apical and lateral sides of gut epithelial cells.
During oogenesis, bbg protein is expressed in the profollicular mesoderm, a layer of follicle cells that separates the germline cyst found at the posterior end of the germarium, from the anterior neighbouring younger cyst; strongly expressed in polar follicle cells; weakly expressed in somatic follicle cells surrounding early egg chambers; in follicle cells surrounding the oocyte; and in the oocyte nucleus. During embryogenesis, bbg protein is predominantly expressed in the developing gut. bbg protein is first detected at embryonic stage 6, in the posterior midgut primordium. bbg protein is expressed in the invaginating hindgut primordium by stage 7, in the anterior midgut primordium at stages 9-10, and in the forgut primordium by stages 11-12. Gut expression is maintained though late embryogenesis, and becomes restricted to the pharynx and proventriculus at late embryonic stages. bbg protein expression in the dorsal ectoderm begins at embryonic stage 6; this expression is restricted to the dorsal edge of the dorsal ectoderm by embryonic stage 9-10. In the wing disc, bbg protein is expressed at the presumptive wing margin, and in a similar pattern in the haltere disc. bbg protein is expressed in a pair of cell clusters near the center of the leg discs; at the medial side of the antennal disc; in a ring-shaped pattern in the larval optic lobe; and at and posterior to the morphogenetic furrow of the eye disc. During pupal eye development, bbg protein is also specifically and dynamically expressed in cone cells, mechanosensory bristle cells, and in secondary and tertiary pigment cells as each cell type becomes specified.
Comment: early stages
GBrowse - Visual display of RNA-Seq signals
View Dmel\bbg in GBrowse 23-42
3-42
3-36.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: bbg CG9587
Source for merge of: bbg CG9598 C96
Source for merge of: bbg CG9598
Annotations CG9598 and CG9587 merged as CG42230 in release 5.5 of the genome annotation.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
The gene is named "big bang" based on the fact that the gene is quite large, and mutants all appear to be mildly bang-sensitive.