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Gene Dmel\cnir

General Information
Symbol	Dmel\cnir	Species	D. melanogaster
Name	cornichon related	Annotation symbol	CG17262
Feature type	protein_coding_gene	FlyBase ID	FBgn0243513
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	23C5-23C5	Sequence location	2L:3,038,826..3,039,812 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene cornichon related is referred to in FlyBase by the symbol Dmel\cnir (CG17262, FBgn0243513). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: vesicle-mediated transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Cornichon. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1638047_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of cnir. Gene sequence location is 2L:3038826..3039812.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN27791 HFA00499
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 23C5-23C5   Limits computationally determined from genome sequence between P{PZ}lilli00632 and P{PZ}toc01361
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\cnir for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) cnir-RA FBtr0077666  NM_134901   871   157
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein cnir-PA   FBpp0077350   18.4   157   6.33     NP_608745   AAF51153
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Cornichon (IPR003377)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF51153   BT083468   EY198554
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VQL3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0243513    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0243513 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0243513 expression level Developmental Stage   Expression Level embryo 00-02hr    1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr    1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1812) embryo 02-04hr  (459) embryo 04-06hr  (634) embryo 06-08hr  (909) embryo 08-10hr  (1098) embryo 10-12hr  (1507) embryo 12-14hr  (1182) embryo 14-16hr  (743) embryo 16-18hr  (649) embryo 18-20hr  (466) embryo 20-22hr  (313) embryo 22-24hr  (418) larva L1  (338) larva L2  (246) larva L3 12hr old  (219) larva L3 puffstage 1-2  (214) larva L3 puffstage 3-6  (339) larva L3 puffstage 7-9  (574) white prepupae new  (519) white prepupae 12hr  (558) white prepupae 24hr  (814) pupae 2d postWPP  (1090) pupae 3d postWPP  (554) pupae 4d postWPP  (278) adult male 01day  (217) adult male 05day  (246) adult male 30day  (202) adult female 01day  (377) adult female 05day  (863) adult female 30day  (828) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1812) embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr  1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr    1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr    1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0243513 expression level Developmental Stage   Expression Level embryo 00-02hr    1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr    1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1812) embryo 02-04hr  (459) embryo 04-06hr  (634) embryo 06-08hr  (909) embryo 08-10hr  (1098) embryo 10-12hr  (1507) embryo 12-14hr  (1182) embryo 14-16hr  (743) embryo 16-18hr  (649) embryo 18-20hr  (466) embryo 20-22hr  (313) embryo 22-24hr  (418) larva L1  (338) larva L2  (246) larva L3 12hr old  (219) larva L3 puffstage 1-2  (214) larva L3 puffstage 3-6  (339) larva L3 puffstage 7-9  (574) white prepupae new  (519) white prepupae 12hr  (558) white prepupae 24hr  (814) pupae 2d postWPP  (1090) pupae 3d postWPP  (554) pupae 4d postWPP  (278) adult male 01day  (217) adult male 05day  (246) adult male 30day  (202) adult female 01day  (377) adult female 05day  (863) adult female 30day  (828) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr  1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr    1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1812 embryo 02-04hr    459 embryo 04-06hr    634 embryo 06-08hr    909 embryo 08-10hr    1098 embryo 10-12hr    1507 embryo 12-14hr    1182 embryo 14-16hr    743 embryo 16-18hr    649 embryo 18-20hr    466 embryo 20-22hr    313 embryo 22-24hr    418 larva L1    338 larva L2    246 larva L3 12hr old    219 larva L3 puffstage 1-2    214 larva L3 puffstage 3-6    339 larva L3 puffstage 7-9    574 white prepupae new    519 white prepupae 12hr    558 white prepupae 24hr    814 pupae 2d postWPP    1090 pupae 3d postWPP    554 pupae 4d postWPP    278 adult male 01day    217 adult male 05day    246 adult male 30day    202 adult female 01day    377 adult female 05day    863 adult female 30day    828 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0243513    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0243513 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0243513 expression level Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0243513 expression level Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    104.125 Larval Midgut    21.1 Larval Hindgut    19.2 Larval Malpighian Tubules    34.2 Larval Fat Body    30.8 Larval Salivary Gland    55.1 Larval Trachea    47.275 Larval Carcass    44.35 Adult Head    60.7 Adult Eye    167.525 Adult Brain    110 Adult Thoracic-Abdominal Ganglion    63.1 Adult Crop    29.7 Adult Midgut    22.2 Adult Hindgut    24.7 Adult Malpighian Tubules no informative data Adult Fat Body    16.9 Adult Salivary Gland    38.7 Adult Heart    19.8 Adult VirginFemale Spermatheca    19.7 Adult InseminatedFemale Spermatheca    19.4 Adult Ovary    166.1 Adult Testis    12.3 Adult Male Accessory Gland    34.2 Adult Carcass    24.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules no informative data Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    60.7   NA  Eye    167.525   NA  Brain    110   104.125  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    63.1   NA  Crop    29.7   21.1  Midgut    22.2   19.2  Hindgut    24.7   34.2  Malpighian Tubules    no informative data   30.8  Fat Body    16.9   55.1  Salivary Gland    38.7   NA  Heart    19.8   47.275  Trachea    NA   NA  VirginFemale Spermatheca    19.7   NA  InseminatedFemale Spermatheca    19.4   NA  Ovary    166.1   NA  Testis    12.3   NA  Male Accessory Gland    34.2   44.35  Carcass    24.1 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0243513 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17262-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 cnirGD856 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of cnir Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of cnir Class Mutagen Stocks Known lesion cnirGD856 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes cnirKK107791 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes cnircniUTR.PB in vitro construct - regulatory fusion in vitro construct - genomic fragment 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7014 (Ryder, 2004.4.26) Df(2L)JS7 (Bokel et al., 2006)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK107791} NA characterization construct P{pcni::cnir.PB} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
vesicle-mediated transport inferred from mutant phenotype (Bokel et al., 2006)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
intracellular signal transduction inferred from electronic annotation with InterPro:IPR003377 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
membrane inferred from electronic annotation with InterPro:IPR003377 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions cnir allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0243513 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33520
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs	Dpse\GA14423
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010119-PA Aedes aegypti (mosquito) AGAP009116-PA Anopheles gambiae (mosquito) XP_001120167.1 Apis mellifera (honey bee) At1g62880.1 Arabidopsis thaliana (wall cress) 271153 Branchiostoma floridae (lancelet) 275888 Branchiostoma floridae (lancelet) ENSBTAP00000025936 Bos taurus (bovine) ENSCAFP00000024076 Canis familiaris (dog) ENSCINP00000027516 Ciona intestinalis (sea squirt) CME060C Cyanidioschyzon merolae (red alga) CPIJ000776 Culex pipens (mosquito) ENSCPOP00000006588 Cavia porcellus (guinea pig) 56436 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000015622 Ciona savignyi (sedentary tunicate) 227547 Capitella spl (polychaete worm) 193338 Daphnia pulex (daphnia) ENSDARP00000095022 Danio rerio (zebra fish) ENSECAP00000008800 Equus caballus (horse) ENSGACP00000018525 Gymnopilus aculeatus (mushroom) ENSGALP00000031314 Gallus gallus (chicken) 66732 Hypsipyla robusta (cedar shoot borer) ENSP00000355825 Homo sapiens (human) ISCW012129-PA Ixodes scapularis (deer tick) 203935 Lottia gigantea (owl limpet) ENSMODP00000006375 Monodelphis domestica (gray opossum) ENSMMUP00000012995 Macaca mulatta (rhesus monkey) ENSMUSP00000075351 Mus musculus (house mouse) 167432 Nematostella vectensis (starlet anemone) XP_001604514.1 Nasonia vitripennis (wasp) ENSOANP00000002315 Ornithorynchus anatinus (platypus) ENSORLP00000005195 Oryzias latipes (japanese killifish) LOC_Os06g04500.1 Oryza sativa (asian rice) PHUM002710-PA Pediculus humanus (human body louse) 165393 Physcomitrella patens (moss) ENSPPYP00000000184 Pongo pygmaeus (orangutan) 817312 Populus trichocarpa (black cottonwood) 837072 Populus trichocarpa (black cottonwood) ENSPTRP00000003397 Pan troglodytes (chimpanzee) ENSRNOP00000004939 Rattus norvegicus (norway rat) 5010414 Sorghum bicolor (sorghum) 32218 Trichoplax adhaerens (metazoa) XP_968817.1 Tribolium castaneum (red flour beetle) ENSTNIP00000022938 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000018768 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000040193 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12825 NV13420 LH17434 ISCW012129 FBgn0232536 FBgn0216960 FBgn0198131 FBgn0194176 FBgn0173078 JGI_V11_193338 FBgn0074451 FBgn0157170 FBgn0139839 FBgn0117817 FBgn0116594 FBgn0092534 CPIJ000776 ACYPI47469 GB11374 AGAP009116 AAEL010119 PHUM603190
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v104009 P{KK107791}VIE-260B v2614 w1118; P{GD856}v2614 v2615 w1118; P{GD856}v2615
Genomic Clones ( 2 )
	BACR23N06 BACR48B06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 1 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP10557
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0243513 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33520
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: cnir CG17262 (Bokel et al., 2006)
Source for database merge of
Additional comments	FlyBase curator comment: the insertion in the "c00569" Exelixis line (PBac{PB}CG17221c00569) was originally assigned to the CG17262 gene in FBrf0179797, resulting in the "CG17262c00569" (FBal0162063) allele. However, FBrf0184340 shows that the insertion is actually within CG17221. (Bloomington Drosophila Stock Center, 2004.11.6)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_134901 RefSeq (Proteins) • NP_608745 DDBJ / EMBL / GenBank • AAF51153 Entrez Gene - A searchable database of RefSeq genes. • 33520 UniProtKB/TrEMBL • Q9VQL3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Cornichon (IPR003377)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0243513 DRSC - Results from RNAi screens. • FBgn0243513 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0243513 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17262-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0243513 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 33520 InParanoid A subset of ortholog calls from InParanoid. • AAEL010119-PA Aedes aegypti (mosquito) AGAP009116-PA Anopheles gambiae (mosquito) XP_001120167.1 Apis mellifera (honey bee) At1g62880.1 Arabidopsis thaliana (wall cress) 271153 Branchiostoma floridae (lancelet) 275888 Branchiostoma floridae (lancelet) ENSBTAP00000025936 Bos taurus (bovine) ENSCAFP00000024076 Canis familiaris (dog) ENSCINP00000027516 Ciona intestinalis (sea squirt) CME060C Cyanidioschyzon merolae (red alga) CPIJ000776 Culex pipens (mosquito) ENSCPOP00000006588 Cavia porcellus (guinea pig) 56436 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000015622 Ciona savignyi (sedentary tunicate) 227547 Capitella spl (polychaete worm) 193338 Daphnia pulex (daphnia) ENSDARP00000095022 Danio rerio (zebra fish) ENSECAP00000008800 Equus caballus (horse) ENSGACP00000018525 Gymnopilus aculeatus (mushroom) ENSGALP00000031314 Gallus gallus (chicken) 66732 Hypsipyla robusta (cedar shoot borer) ENSP00000355825 Homo sapiens (human) ISCW012129-PA Ixodes scapularis (deer tick) 203935 Lottia gigantea (owl limpet) ENSMODP00000006375 Monodelphis domestica (gray opossum) ENSMMUP00000012995 Macaca mulatta (rhesus monkey) ENSMUSP00000075351 Mus musculus (house mouse) 167432 Nematostella vectensis (starlet anemone) XP_001604514.1 Nasonia vitripennis (wasp) ENSOANP00000002315 Ornithorynchus anatinus (platypus) ENSORLP00000005195 Oryzias latipes (japanese killifish) LOC_Os06g04500.1 Oryza sativa (asian rice) PHUM002710-PA Pediculus humanus (human body louse) 165393 Physcomitrella patens (moss) ENSPPYP00000000184 Pongo pygmaeus (orangutan) 817312 Populus trichocarpa (black cottonwood) 837072 Populus trichocarpa (black cottonwood) ENSPTRP00000003397 Pan troglodytes (chimpanzee) ENSRNOP00000004939 Rattus norvegicus (norway rat) 5010414 Sorghum bicolor (sorghum) 32218 Trichoplax adhaerens (metazoa) XP_968817.1 Tribolium castaneum (red flour beetle) ENSTNIP00000022938 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000018768 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000040193 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 33520 modMine - Data generated by the modENCODE project. • FBgn0243513 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB12825 NV13420 LH17434 ISCW012129 FBgn0232536 FBgn0216960 FBgn0198131 FBgn0194176 FBgn0173078 JGI_V11_193338 FBgn0074451 FBgn0157170 FBgn0139839 FBgn0117817 FBgn0116594 FBgn0092534 CPIJ000776 ACYPI47469 GB11374 AGAP009116 AAEL010119 PHUM603190
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG17262 (Bokel et al., 2006, Keleman et al., 2009.8.5) cnir   Cnir (Bokel et al., 2006)
Name Synonym	CG17262   Cni-related (Bokel et al., 2006) cornichon related (Dass et al., 2003)
Secondary FlyBase IDs
	FBgn0031499 FBgn0064188
References ( 11 )
Research paper	Bokel et al., 2006, Development 133(3): 459--470 Drosophila Cornichon acts as cargo receptor for ER export of the TGFalpha-like growth factor Gurken. [FBrf0190275]
Supplementary material	Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Daas, 2003.2.17, Helping FlyBase: ADRC-10793. Helping FlyBase: ADRC-10793. [FBrf0155438]
Abstract	Dass et al., 2003, A. Dros. Res. Conf. 44: 56 The role of Cornichon (Cni) in subcellular transport of Gurken (Grk). [FBrf0155078]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]