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Gene Dmel\exba

General Information
Symbol	Dmel\exba	Species	D. melanogaster
Name	extra bases	Annotation symbol	CG2922
Feature type	protein_coding_gene	FlyBase ID	FBgn0250753
Gene Model Status	Current	Stock availability	23 publicly available
Also Known As	eIF-5C, kra, elF-5C, l(3)03022
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	83B4-83B4	Sequence location	3R:1,421,086..1,426,891 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene extra bases is referred to in FlyBase by the symbol Dmel\exba (CG2922, FBgn0250753). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; ribosome binding; translation initiation factor binding. There is experimental evidence that it is involved in the biological process: neuron fate commitment; oogenesis; long-term memory; negative regulation of translation; axon midline choice point recognition. 39 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Armadillo-type fold; MIF4-like, type 1/2/3; eIF4-gamma/eIF5/eIF2-epsilon. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. Gene sequence location is 3R:1421086..1426891.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features HFA12320 BKN22996
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 83B4-83B4   Left limit from in situ hybridisation (FBrf0067338) Right limit from in situ hybridisation (FBrf0067338); Limits computationally determined from genome sequence between P{PZ}Snr101319&P{PZ}Itp-r83A05616 and P{lacW}Atus1938
Experimentally Determined Cytological Location
Cytogenetic map Notes References 83B4-83B4     (Wan, 2000.11.30) 83B4-83B2   (determined by in situ hybridisation)   (Spradling et al., 1999) 83B1-83B5   (determined by in situ hybridisation)   (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\exba for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) exba-RA FBtr0078744  NM_169074   2156   422 exba-RB FBtr0078749  NM_169075   1846   422 exba-RC FBtr0078746  NM_169076   2085   422 exba-RD FBtr0078748  NM_169077   2025   422 exba-RE FBtr0078750  NM_169078   1722   422 exba-RF FBtr0078747  NM_169079   1955   422 exba-RG FBtr0078745  NM_079514   1647   422
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein exba-PA   FBpp0078393   49.2   422   5.46     NP_730958   AAF51996 exba-PB   FBpp0078398   49.2   422   5.46     NP_730959   AAG22214 exba-PC   FBpp0078395   49.2   422   5.46     NP_730960   AAF51995 exba-PD   FBpp0078397   49.2   422   5.46     NP_730961   AAN13246 exba-PE   FBpp0078399   49.2   422   5.46     NP_730962   AAN13247 exba-PF   FBpp0078396   49.2   422   5.46     NP_730963   AAN13248 exba-PG   FBpp0078394   49.2   422   5.46     NP_524238   AAN13249
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • eIF4-gamma/eIF5/eIF2-epsilon (IPR003307) Armadillo-type fold (IPR016024) MIF4-like, type 1/2/3 (IPR016021)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201655   AA202725   AA202727   AA246238   AA263324   AA264112   AA264126   AA264219   AA264221   AA264579   AA264776   AA264960   AA390494   AA391055   AA391370   AA391443   AA392571   AA438336   AA438398   AA439066   AA439451   AA439703   AA440043   AA440402   AA440491   AA440858   AA441238   AA536418   AA539999   AA540051   AA540338   AA540357   AA540420   AA540617   AA540949   AA541131   AA541155   AA567833   AA694720   AA695530   AA695982   AA696942   AA697007   AA697033   AA697107   AA735439   AA735842   AA801897   AA801948   AA803397   AA803715   AA817450   AA820068   AA820429   AA820443   AA820662   AA820742   AA820751   AA820922   AA941275   AA941397   AA941572   AA941839   AA941915   AA942341   AA942561   AA948809   AA949459   AA949685   AA949896   AA949921   AA949999   AA950015   AA950029   AA950337   AA951533   AA951570   AA951921   AA952009   AA952137   AA978852   AA979218   AA979292   AA979643   AA990743   AA990798   AA990845   AE014297 AAF51995   AE014297 AAF51996   AE014297 AAG22214   AE014297 AAN13246   AE014297 AAN13247   AE014297 AAN13248   AE014297 AAN13249   AF325529 AAK01218   AI062112   AI062538   AI062605   AI063237   AI064143   AI064649   AI106759   AI106877   AI106880   AI107374   AI107435   AI107759   AI108312   AI109261   AI113660   AI114265   AI114312   AI134213   AI135002   AI238374   AI258520   AI258574   AI258876   AI259903   AI260054   AI260407   AI293801   AI294958   AI295686   AI389005   AI389018   AI402592   AI403708   AI404147   AI404419   AI404589   AI405188   AI405721   AI455126   AI456129   AI456530   AI456617   AI456757   AI511960   AI512401   AI513198   AI514330   AI514521   AI514539   AI514795   AI514812   AI514897   AI515242   AI515244   AI515808   AI516096   AI516220   AI516251   AI516490   AI516801   AI517842   AI517960   AI518616   AI518617   AI518694   AI519035   AI519109   AI519322   AI519325   AI519342   AI519506   AI519508   AI519780   AI520336   AI530860   AI531362   AI531363   AI531470   AI531872   AI533061   AI533359   AI534474   AI541795   AI542483   AI542572   AI542911   AI543637   AI543876   AI544097   AI544170   AI544252   AI544253   AI945588   AI945813   AQ026184   AQ026337   AQ073043   AQ073893   AQ254887   AX260087   AY058505 AAL13734   AY231783   BE662147   BE662226   BE975225   BE977049   BF485961   BF494630   BF497722   BF502174   BF502934   BF503718   BG640395   BG640607   BI161507   BI161508   BI163740   BI164208   BI165518   BI166175   BI166470   BI167109   BI168084   BI169742   BI171037   BI172155   BI172226   BI173072   BI173089   BI173466   BI173841   BI212760   BI214829   BI215384   BI216310   BI216960   BI228321   BI230523   BI230761   BI232940   BI236071   BI237463   BI239304   BI240022   BI241774   BI241901   BI242690   BI243856   BI352776   BI352953   BI354592   BI354718   BI355473   BI355509   BI356744   BI356808   BI357323   BI358535   BI361683   BI362588   BI363501   BI367253   BI368608   BI368826   BI369296   BI371845   BI372647   BI373057   BI373214   BI373958   BI374063   BI374571   BI374575   BI375224   BI375599   BI481565   BI481784   BI482657   BI483152   BI483172   BI484643   BI610730   BI626260   BI626535   BI632910   BI633866   BI637585   BI638481   BI638590   BI638805   BI639084   BI639790   BI640901   BI641386   BI641387   BP540455   BP540456   BP542673   BP542705   BP544007   BP544008   BP545769   BP548570   BP548927   BP548928   BP551856   BP551990   BP551991   BP556946   BP556947   BP558216   BQ102810   BT014928   CA806121   CA806610   CA807105   CA807564   CA807834   CK132203   CK132893   CK657475   CK660069   CK660667   CK660859   CK661782   CK661953   CL844387   CO156268   CO177095   CO179614   CO184235   CO188765   CO189981   CO190835   CO192619   CO192915   CO267004   CO268374   CO268821   CO270816   CO273122   CO287606   CO288508   CO295584   CO295943   CO301965   CO305184   CO307894   CO307904   CO312807   CO316769   CO321463   CO322257   CO327136   CO328457   CO329885   CO339241   CO339337   CO341184   CZ467237   CZ470294   CZ472113   CZ472191   CZ472405   CZ472406   CZ476335   CZ477206   CZ487952   CZ487953   DQ440242   EC061742   EC062936   EC063997   EC069555   EC069973   EC074089   EC075453   EC085994   EC086086   EC088712   EC196137   EC202548   EC203688   EC204016   EC207410   EC207614   EC209265   EC213710   EC218235   EC225369   EC227224   EC230149   EC231630   EC236175   EC240356   EC241120   EC243782   EC247159   EC248412   EC248852   EC251714   EC254083   EC256483   EC257606   EC257646   EC261207   EL874861   EL874862   EL877011   EV576195   EV581740   EV582174   EV587667   EV589443   EV592387   EV596475   EV597432   EV597756   EV600448   GH847296   GH942708   GH942888   GH947550   GH949296   GH949958   GH949988   GH952474   GH953571   GH956686   GH957920   GH962703   GH964019   GH967780   GH976727   GH981360   GH982227
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VNE2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0250753    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0250753 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0250753 expression level Developmental Stage   Expression Level embryo 00-02hr    17382 embryo 02-04hr    24232 embryo 04-06hr    18522 embryo 06-08hr    16229 embryo 08-10hr    18052 embryo 10-12hr    14903 embryo 12-14hr    24230 embryo 14-16hr    9947 embryo 16-18hr    11477 embryo 18-20hr    7073 embryo 20-22hr    8071 embryo 22-24hr    11323 larva L1    9413 larva L2    14854 larva L3 12hr old    9011 larva L3 puffstage 1-2    9211 larva L3 puffstage 3-6    11812 larva L3 puffstage 7-9    19845 white prepupae new    17772 white prepupae 12hr    12154 white prepupae 24hr    11084 pupae 2d postWPP    11273 pupae 3d postWPP    10234 pupae 4d postWPP    7951 adult male 01day    9842 adult male 05day    8308 adult male 30day    6210 adult female 01day    8052 adult female 05day    20244 adult female 30day    18502 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (17382) embryo 02-04hr  (24232) embryo 04-06hr  (18522) embryo 06-08hr  (16229) embryo 08-10hr  (18052) embryo 10-12hr  (14903) embryo 12-14hr  (24230) embryo 14-16hr  (9947) embryo 16-18hr  (11477) embryo 18-20hr  (7073) embryo 20-22hr  (8071) embryo 22-24hr  (11323) larva L1  (9413) larva L2  (14854) larva L3 12hr old  (9011) larva L3 puffstage 1-2  (9211) larva L3 puffstage 3-6  (11812) larva L3 puffstage 7-9  (19845) white prepupae new  (17772) white prepupae 12hr  (12154) white prepupae 24hr  (11084) pupae 2d postWPP  (11273) pupae 3d postWPP  (10234) pupae 4d postWPP  (7951) adult male 01day  (9842) adult male 05day  (8308) adult male 30day  (6210) adult female 01day  (8052) adult female 05day  (20244) adult female 30day  (18502) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (17382) embryo 02-04hr  (24232) embryo 04-06hr  (18522) embryo 06-08hr  (16229) embryo 08-10hr  (18052) embryo 10-12hr  (14903) embryo 12-14hr  (24230) embryo 14-16hr  (9947) embryo 16-18hr  (11477) embryo 18-20hr  (7073) embryo 20-22hr  (8071) embryo 22-24hr  (11323) larva L1  (9413) larva L2  (14854) larva L3 12hr old  (9011) larva L3 puffstage 1-2  (9211) larva L3 puffstage 3-6  (11812) larva L3 puffstage 7-9  (19845) white prepupae new  (17772) white prepupae 12hr  (12154) white prepupae 24hr  (11084) pupae 2d postWPP  (11273) pupae 3d postWPP  (10234) pupae 4d postWPP  (7951) adult male 01day  (9842) adult male 05day  (8308) adult male 30day  (6210) adult female 01day  (8052) adult female 05day  (20244) adult female 30day  (18502) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (17382) embryo 02-04hr  (24232) embryo 04-06hr  (18522) embryo 06-08hr  (16229) embryo 08-10hr  (18052) embryo 10-12hr  (14903) embryo 12-14hr  (24230) embryo 14-16hr    9947 embryo 16-18hr  (11477) embryo 18-20hr    7073 embryo 20-22hr    8071 embryo 22-24hr  (11323) larva L1    9413 larva L2  (14854) larva L3 12hr old    9011 larva L3 puffstage 1-2    9211 larva L3 puffstage 3-6  (11812) larva L3 puffstage 7-9  (19845) white prepupae new  (17772) white prepupae 12hr  (12154) white prepupae 24hr  (11084) pupae 2d postWPP  (11273) pupae 3d postWPP  10234 pupae 4d postWPP    7951 adult male 01day    9842 adult male 05day    8308 adult male 30day    6210 adult female 01day    8052 adult female 05day  (20244) adult female 30day  (18502) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17382 embryo 02-04hr    24232 embryo 04-06hr    18522 embryo 06-08hr    16229 embryo 08-10hr    18052 embryo 10-12hr    14903 embryo 12-14hr    24230 embryo 14-16hr    9947 embryo 16-18hr    11477 embryo 18-20hr    7073 embryo 20-22hr    8071 embryo 22-24hr    11323 larva L1    9413 larva L2    14854 larva L3 12hr old    9011 larva L3 puffstage 1-2    9211 larva L3 puffstage 3-6    11812 larva L3 puffstage 7-9    19845 white prepupae new    17772 white prepupae 12hr    12154 white prepupae 24hr    11084 pupae 2d postWPP    11273 pupae 3d postWPP    10234 pupae 4d postWPP    7951 adult male 01day    9842 adult male 05day    8308 adult male 30day    6210 adult female 01day    8052 adult female 05day    20244 adult female 30day    18502 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0250753 expression level Developmental Stage   Expression Level embryo 00-02hr    17382 embryo 02-04hr    24232 embryo 04-06hr    18522 embryo 06-08hr    16229 embryo 08-10hr    18052 embryo 10-12hr    14903 embryo 12-14hr    24230 embryo 14-16hr    9947 embryo 16-18hr    11477 embryo 18-20hr    7073 embryo 20-22hr    8071 embryo 22-24hr    11323 larva L1    9413 larva L2    14854 larva L3 12hr old    9011 larva L3 puffstage 1-2    9211 larva L3 puffstage 3-6    11812 larva L3 puffstage 7-9    19845 white prepupae new    17772 white prepupae 12hr    12154 white prepupae 24hr    11084 pupae 2d postWPP    11273 pupae 3d postWPP    10234 pupae 4d postWPP    7951 adult male 01day    9842 adult male 05day    8308 adult male 30day    6210 adult female 01day    8052 adult female 05day    20244 adult female 30day    18502 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (17382) embryo 02-04hr  (24232) embryo 04-06hr  (18522) embryo 06-08hr  (16229) embryo 08-10hr  (18052) embryo 10-12hr  (14903) embryo 12-14hr  (24230) embryo 14-16hr  (9947) embryo 16-18hr  (11477) embryo 18-20hr  (7073) embryo 20-22hr  (8071) embryo 22-24hr  (11323) larva L1  (9413) larva L2  (14854) larva L3 12hr old  (9011) larva L3 puffstage 1-2  (9211) larva L3 puffstage 3-6  (11812) larva L3 puffstage 7-9  (19845) white prepupae new  (17772) white prepupae 12hr  (12154) white prepupae 24hr  (11084) pupae 2d postWPP  (11273) pupae 3d postWPP  (10234) pupae 4d postWPP  (7951) adult male 01day  (9842) adult male 05day  (8308) adult male 30day  (6210) adult female 01day  (8052) adult female 05day  (20244) adult female 30day  (18502) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (17382) embryo 02-04hr  (24232) embryo 04-06hr  (18522) embryo 06-08hr  (16229) embryo 08-10hr  (18052) embryo 10-12hr  (14903) embryo 12-14hr  (24230) embryo 14-16hr  (9947) embryo 16-18hr  (11477) embryo 18-20hr  (7073) embryo 20-22hr  (8071) embryo 22-24hr  (11323) larva L1  (9413) larva L2  (14854) larva L3 12hr old  (9011) larva L3 puffstage 1-2  (9211) larva L3 puffstage 3-6  (11812) larva L3 puffstage 7-9  (19845) white prepupae new  (17772) white prepupae 12hr  (12154) white prepupae 24hr  (11084) pupae 2d postWPP  (11273) pupae 3d postWPP  (10234) pupae 4d postWPP  (7951) adult male 01day  (9842) adult male 05day  (8308) adult male 30day  (6210) adult female 01day  (8052) adult female 05day  (20244) adult female 30day  (18502) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  17382 embryo 02-04hr  (24232) embryo 04-06hr  18522 embryo 06-08hr  16229 embryo 08-10hr  18052 embryo 10-12hr  14903 embryo 12-14hr  (24230) embryo 14-16hr    9947 embryo 16-18hr  11477 embryo 18-20hr    7073 embryo 20-22hr    8071 embryo 22-24hr  11323 larva L1    9413 larva L2  14854 larva L3 12hr old    9011 larva L3 puffstage 1-2    9211 larva L3 puffstage 3-6  11812 larva L3 puffstage 7-9  19845 white prepupae new  17772 white prepupae 12hr  12154 white prepupae 24hr  11084 pupae 2d postWPP  11273 pupae 3d postWPP  10234 pupae 4d postWPP    7951 adult male 01day    9842 adult male 05day    8308 adult male 30day    6210 adult female 01day    8052 adult female 05day  20244 adult female 30day  18502 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17382 embryo 02-04hr    24232 embryo 04-06hr    18522 embryo 06-08hr    16229 embryo 08-10hr    18052 embryo 10-12hr    14903 embryo 12-14hr    24230 embryo 14-16hr    9947 embryo 16-18hr    11477 embryo 18-20hr    7073 embryo 20-22hr    8071 embryo 22-24hr    11323 larva L1    9413 larva L2    14854 larva L3 12hr old    9011 larva L3 puffstage 1-2    9211 larva L3 puffstage 3-6    11812 larva L3 puffstage 7-9    19845 white prepupae new    17772 white prepupae 12hr    12154 white prepupae 24hr    11084 pupae 2d postWPP    11273 pupae 3d postWPP    10234 pupae 4d postWPP    7951 adult male 01day    9842 adult male 05day    8308 adult male 30day    6210 adult female 01day    8052 adult female 05day    20244 adult female 30day    18502 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0250753    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0250753 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0250753
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal exbaCB02125 lethal | pupal stage, with Scer\GAL4pnr-MD237 exbaGD8839 lethal | recessive exba03022 exbaj9B6 semi-lethal exba03022 viable exbaEY11022 exbaf05932 Sterility Allele female sterile | germline clone exba1 fertile exbaEY11022 exbaf05932 Other Phenotypes Allele memory defective exbakrasavietz neuroanatomy defective | embryonic stage (with exba1) exba2 neuroanatomy defective | embryonic stage (with exba2) exba1 Phenotype manifest in Allele axon & pCC neuron (with exba1) exba2 axon & pCC neuron (with exba2) exba1
Classical Alleles ( 33 )
For All Classical Alleles Show
Allele of exba Class Mutagen Stocks Known lesion exbaf05932 piggyBac transposase 2 -- exbaj9B6 P-element activity 2 -- exba03022 P-element activity 1 -- exba5-SZ-3068 1 -- exbac01538 piggyBac transposase 1 -- exbac05843 piggyBac transposase 1 -- exbaCB-0923-3 1 -- exbaCB-5654-3 1 -- exbaCB-5753-3 1 -- exbaCB-6007-3 1 -- exbad01235 P-element activity 1 -- exbad01372 P-element activity 1 -- exbaEY11022 P-element activity 1 -- exbaf05390 piggyBac transposase 1 -- exbaNP2078 1 -- exbaNP3229 1 -- exbaNP3614 1 -- exba1 P-element activity 0 Yes exba2 P-element activity 0 Yes exba5-HA-2635 0 -- exbaBA00280 piggyBac transposase 0 Yes exbaCB02125 P-element activity 0 Yes exbaCTG-240.1 P-element activity 0 Yes exbad01733 P-element activity 0 -- exbad02932 0 -- exbad08623 P-element activity 0 -- exbad10311 P-element activity 0 -- exbaEP3297 P-element activity 0 -- exbaEP3591 P-element activity 0 -- exbaEP428 P-element activity 0 Yes exbaf06989 0 -- exbakrasavietz P-element activity 0 -- exbaunspecified 0 --
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of exba Class Mutagen Stocks Known lesion exbaGD8839 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes exbaJF02556 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes exbaKK102900 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes exba12A.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes exba7A.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes exbaScer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)ED5177 (Roote, 2004.7.20) Df(3R)Exel6144 (Ryder, 2004.4.26)
Not disrupted in	Df(3R)ED5177 (Ryder and Roote, 2004.11.10)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8839} NA P{KK102900} NA P{TRiP.JF02556} NA P{UAS-kra.HA.7A} NA P{UAS-kra.HA.12A} NA P{UAS-kra.HA} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}exbaj9B6 No P{PZ}exba03022 No insertion of mobile activating element P{EP}exbaEP428 NA P{EP}exbaEP3297 NA P{EP}exbaEP3591 NA P{EPgy2}exbaEY11022 NA P{XP}exbad01235 NA P{XP}exbad01372 NA P{XP}exbad01733 NA P{XP}exbad02932 NA P{XP}exbad08623 NA P{XP}exbad10311 NA miscellaneous insertions P{PTT-GB}exbaCB02125 NA P{RS3}exbaCB-0923-3 NA P{RS3}exbaCB-5654-3 NA P{RS3}exbaCB-5753-3 NA P{RS3}exbaCB-6007-3 NA P{RS5}exba5-HA-2635 NA P{RS5}exba5-SZ-3068 NA P{UASp-CTG.240}exbaCTG-240.1 NA PBac{HpaI-GFP.A}exbaBA00280 NA PBac{PB}exbac01538 NA PBac{PB}exbac05843 NA PBac{WH}exbaf05390 NA PBac{WH}exbaf05932 NA PBac{WH}exbaf06989 NA insertion of enhancer trap binary system P{GAL4}exbakrasavietz No P{GawB}exbaNP2078 No P{GawB}exbaNP3229 No P{GawB}exbaNP3614 No
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 11 terms )
Molecular Function
CV term Evidence References
protein binding inferred from physical interaction with eIF-2β (Lee et al., 2007) inferred from physical interaction with RpL5 (Wang et al., 2006) inferred from physical interaction with shot (Lee et al., 2007) ribosome binding inferred from direct assay (Wang et al., 2006) translation initiation factor binding inferred from direct assay (Lee et al., 2007)
Biological Process
CV term Evidence References
axon midline choice point recognition inferred from mutant phenotype (Lee et al., 2007) long-term memory inferred from mutant phenotype (Dubnau et al., 2003) negative regulation of translation inferred from direct assay (Lee et al., 2007) neuron fate commitment inferred from mutant phenotype (Lee et al., 2002) oogenesis inferred from mutant phenotype (Lee et al., 2007)
Cellular Component
CV term Evidence References
axon inferred from direct assay (Lee et al., 2007) cytoplasm inferred from direct assay (Wang et al., 2006) neuronal cell body inferred from direct assay (Lee et al., 2007)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
long-term memory traceable author statement (Greenspan, 2003) RNA metabolic process inferred from electronic annotation with InterPro:IPR016021 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions exba allele Gene References exba03022 Kr (Carrera et al., 1998) unspecified robo (Lee et al., 2007) shot (Lee et al., 2007) sli (Lee et al., 2007)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65886 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0250753 DroID - A comprehensive database of gene and protein interactions. • FBgn0250753 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40680
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20763 Dere\GG10932 Dgri\GH17376 Dmoj\GI23920 Dper\GL22291 Dpse\GA15521 Dsec\GM10614 Dsim\GD19602 Dvir\GJ24012 Dwil\GK22654 Dyak\GE24159
Curated drosophilid orthologs	Dpse\GA15521   Dyak\GE24159
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012026-PA Aedes aegypti (mosquito) AGAP002413-PA Anopheles gambiae (mosquito) XP_395256.3 Apis mellifera (honey bee) XP_001943194.1 Acyrthosiphon pisum (pea aphid) At5g36230.1 Arabidopsis thaliana (wall cress) 37336 Batrachochytrium dendrobatidis (chytrid fungus) 120788 Branchiostoma floridae (lancelet) 132276 Branchiostoma floridae (lancelet) ENSBTAP00000007948 Bos taurus (bovine) ENSCAFP00000017510 Canis familiaris (dog) cn04243 Cryptococcus neoformans (yeast-like fungus) CPIJ006749 Culex pipens (mosquito) ENSCPOP00000009385 Cavia porcellus (guinea pig) 183179 Chlamidomonas reinhardtii (green alga) 164650 Capitella spl (polychaete worm) 198197 Daphnia pulex (daphnia) ENSDARP00000022789 Danio rerio (zebra fish) ENSECAP00000009614 Equus caballus (horse) ENSGACP00000020646 Gymnopilus aculeatus (mushroom) ENSGALP00000013365 Gallus gallus (chicken) GL50803_7522 Giardia lamblia (flagellated protozoan) 82136 Hypsipyla robusta (cedar shoot borer) ENSP00000387086 Homo sapiens (human) ISCW005690-PA Ixodes scapularis (deer tick) 115834 Lottia gigantea (owl limpet) 16574 Monocosta brevicollis (choanoflagellate) ENSMODP00000018757 Monodelphis domestica (gray opossum) ENSMMUP00000022431 Macaca mulatta (rhesus monkey) ENSMUSP00000051935 Mus musculus (house mouse) 241916 Nematostella vectensis (starlet anemone) XP_001608265.1 Nasonia vitripennis (wasp) ENSOANP00000017152 Ornithorynchus anatinus (platypus) ENSORLP00000000149 Oryzias latipes (japanese killifish) LOC_Os11g21990.1 Oryza sativa (asian rice) PHUM000777-PA Pediculus humanus (human body louse) 228333 Physcomitrella patens (moss) ENSPPYP00000019911 Pongo pygmaeus (orangutan) 814507 Populus trichocarpa (black cottonwood) 814617 Populus trichocarpa (black cottonwood) ENSPTRP00000032377 Pan troglodytes (chimpanzee) ENSRNOP00000019486 Rattus norvegicus (norway rat) 4772058 Sorghum bicolor (sorghum) XP_792300.2 Strongylocentrotus purpuratus (purple sea urchin) 63688 Trichoplax adhaerens (metazoa) XP_973636.1 Tribolium castaneum (red flour beetle) ENSTNIP00000020310 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000014372 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10955 LH20303 ISCW005690 FBgn0067980 FBgn0224631 FBgn0211099 FBgn0191094 FBgn0165560 JGI_V11_198197 FBgn0075538 FBgn0159883 FBgn0146645 FBgn0124846 FBgn0103235 FBgn0097769 CPIJ006749 BGIBMGA008682 ACYPI006482 GB14569 AGAP002413 AAEL015512 AAEL012026 PB23726 PHUM450110 GLEAN_09915
Stocks & Reagents
Stocks Listed in FlyBase ( 23 )
Bloomington	18919 w1118; PBac{WH}exbaf05932
Harvard	- P{XP}exbad01235 - P{XP}exbad01372 - PBac{PB}exbac01538 - PBac{PB}exbac05843 - PBac{WH}exbaf05390 - PBac{WH}exbaf05932
Kyoto	113170 w*; P{GawB}exbaNP3229 113372 w*; P{GawB}exbaNP3614
VDRC	v102609 P{KK102900}VIE-260B v25166 w1118; P{GD8839}v25166 v25165 w1118; P{GD8839}v25165/TM3
	More stocks available...
Genomic Clones ( 2 )
	BACR03P13 BACR24O24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 396 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT07276 LD21309
Other clones	DPiM_LD21309 yak-em_CG2922
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03331 AT04896 AT11982 AT17823 AT18793 AT20066 GH01765 GH02804 GH04185 GH04415 GH05118 GH05604 GH06127 GH06130 GH07122 GH07694 GH08394 GH10064 GH11121 GH11607 GH14408 GH20074 GH20091 GH21840 GH23207 GH23753 GH25123 GM01404 GM02976 GM03553 GM03622 GM04860 GM08749 GM08895 GM08970 GM09093 GM09954 GM10773 GM14078 GM20731 GM21430 GM27536 GM28032 GM30939 GM31161 LD02980 LD07716 LD07846 LD07859 LD08289 LD08458 LD08685 LD10107 LD12290 LD12671 LD14028 LD14989 LD17023 LD19316 LD19388 LD19795 LD19908 LD22907 LD24044 LD24074 LD24501 LD24614 LD25329 LD25525 LD26487 LD27144 LD27257 LD28456 LD28485 LD28591 LD28861 LD29210 LD29473 LD29663 LD29952 LD29974 LD32063 LD32831 LD33026 LD34772 LD36878 LD37309 LD39125 LD40110 LD41056 LD41080 LD42018 LD42918 LD45415 LD46484 LD46511 LD46525 LD46981 LD46983 LP01739 LP01801 LP02174 LP03731 LP04245 LP07026 LP09384 LP13542 LP18316 LP19430 LP19790 LP21494 LP23806 RE03229 RE11009 RE14218 RE38938 RE43759 RE59658 RE63451 RE64138 RE64385 RH66828 SD01606 SD02361 SD02363 SD02527 SD03155 SD04755 SD05147 SD06971 SD07320 SD08823 SD08961 SD09426 SD10505 SD10743 SD10744 SD11403 SD11732 SD19635 SD20777 SD20921 SD21189 SD21533 SD22467 SD23927 SD24667 SD24668 SD26812 SD28042
Other clones	9259 9643 38802 56562 60631 62490 63751 73654 76831 77135 79877 103264 103398 105350 105493 119797 125707 150113 161382 172899 214281.57 214307.57 214413.64 214413.66 214539.60 527320 bs14e08 bs17b08 bs24h10 bs32b12 bs40b05 bs59c03 CK01.16D.A10 CK01.50D.E9 CK01.56D.A4 CK01.62A.H10 CK01.64C.E6 CK01.76A.C12 CK01.76D.F3 CK01.83A.H12 CK01.87A.D8 CK01.121C.G9 Dmel_dig_013631_0697_3057 Dmel_dig_015206_0701_3134 Dmel_dig_021030_0675_0840 Dmel_neb_000947_0923_3687 Dmel_neb_001039_0419_0357 Dmel_neb_001188_0947_3608 Dmel_neb_007456_0633_3686 Dmel_neb_009163_0920_0550 Dmel_neb_011892_0090_0957 Dmel_neb_014636_0950_1235 EC27444 EC34161 EC34774 EK041817 EK045834 EK049863 EK052439 EK060022 EK066264 EK068648 EK091204 EK092827 EK100403 EK109644 EK148301 EK182806 EK185730 EK187743 EK210755 EK212344 EK230016 EK247616 EK255957 EK256109 EK265826 EK294107 EN07664 EP01312 EP01636 EP05926 EP09234 EP12014 ESG012a.E21_D05 ESG014a.E21_G02 ESG016b.E21_C06 ESG018c.E21.1_B08 ESG019d.E21_E05 FGA004F06 FGC015F05 FGC016A02 FGC023E12 FGC033D02 FGH129B09 FGM002F06 FGM215C03 FGM216A04 FGM306D11 FGM313F12 GH01186 GH01865 GH02867 GH11060 GH12611 GH24125 GH24354 GH25839 HL01857 IP06947 IP14941 LD01852 LD02952 LD03948 LD06029 LD06512 LD07702 LD09372 LD10048 LD10510 LD12820 LD13387 LD13513 LD14338 LD15118 LD15903 LD16104 LD19819 LD20148 LD20363 LD20950 LD20983 LD24626 LD24863 LD25768 LD26858 LD27458 LD29011 LD32159 LD33545 LD33674 LD34346 LD34589 LD34682 LD35983 LD36576 LD36695 LD38140 LD38231 LD38232 LD38371 LD38525 LD38864 LD38868 LD38887 LD39123 LD39553 LD40468 LD41480 LD41851 LD42049 LD42376 LD42872 LD43546 LD44268 LD45540 LD46330 LD47619 LP03424 LP08451 LP21787 RE01014 RE03836 RE05437 RE06217 RE06601 RE07419 RE08627 RE12690 RE14429 RE14528 RE14794 RE15819 RE15828 RE16402 RE16960 RE18005 RE20960 RE21769 RE23403 RE24459 RE25833 RE29091 RE32065 RE33691 RE35761 RE36664 RE39101 RE40088 RE41653 RE42945 RE43030 RE45329 RE46010 RE47188 RE48326 RE52972 RE54610 RE54867 RE55432 RE58852 RE60269 RE60455 RE61434 RE61575 RE62196 RE62206 RE62975 RE65374 RE65994 RE66021 RE67777 RH16407 RH67509 RP003643440 RP004047768 RP004073708 RP004127354 RP004144169 RP004178544 RP004178787 RP004188469 RP004207353 RP004222427 RP004232287 RP004255488 RP004256350 RP004313175 RP004462968 RP004508842 RP004522424 UUGC0198
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0250753 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40680
Antibody Information
Other Information
Discoverer
	L. and Y. Jan.
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: eIF-5C CG2922 (FlyBase, 1996-)
Source for database merge of	Source for merge of: eIF-5C anon-WO0172774.49 (FlyBase, 1996-) Source for merge of: eIF-5C extra-bases (Lee et al., 2003) Source for merge of: eIF-5C l(3)03022 (Levis, 2002.6.24) Source for merge of: exba l(3)j9B6 (Lee et al., 2007)
Additional comments	Source for merge of eIF-5C anon-WO0172774.49 was sequence comparison (date:051113). (FlyBase, 1996-) Source for identity of eIF-5C CG2922 was sequence comparison (date:010210). (FlyBase, 1996-)
Other Comments
	dsRNA made from templates generated with primers directed against this gene. (Lee et al., 2007) exba has a role in long-term memory. (Dubnau et al., 2003) exba is required for lineage specification in the nervous system. (Lee et al., 2002) Mutants produce extra neurons. (Lee et al., 2002)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079514 NM_169074 NM_169075 NM_169076 NM_169077 NM_169078 NM_169079 RefSeq (Proteins) • NP_524238 NP_730958 NP_730959 NP_730960 NP_730961 NP_730962 NP_730963 DDBJ / EMBL / GenBank • AA391055 AA439703 AA697033 AA735439 AAF51995 AAF51996 AAG22214 AAK01218 AAL13734 AAN13246 AAN13247 AAN13248 AAN13249 AF325529 AI403708 AI455126 AI456129 AI945588 AI945813 AQ026184 AQ026337 AQ073043 AQ073893 AQ254887 AX260087 AY058505 BE662147 BE662226 CL844387 CZ467237 CZ470294 CZ472113 CZ472191 CZ472405 CZ472406 CZ476335 CZ477206 CZ487952 CZ487953 Entrez Gene - A searchable database of RefSeq genes. • 40680 UniProtKB/TrEMBL • Q9VNE2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • eIF4-gamma/eIF5/eIF2-epsilon (IPR003307) Armadillo-type fold (IPR016024) MIF4-like, type 1/2/3 (IPR016021)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65886 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0250753 DroID - A comprehensive database of gene and protein interactions. • FBgn0250753 DRSC - Results from RNAi screens. • FBgn0250753 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0250753 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0250753 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40680 InParanoid A subset of ortholog calls from InParanoid. • AAEL012026-PA Aedes aegypti (mosquito) AGAP002413-PA Anopheles gambiae (mosquito) XP_395256.3 Apis mellifera (honey bee) XP_001943194.1 Acyrthosiphon pisum (pea aphid) At5g36230.1 Arabidopsis thaliana (wall cress) 37336 Batrachochytrium dendrobatidis (chytrid fungus) 120788 Branchiostoma floridae (lancelet) 132276 Branchiostoma floridae (lancelet) ENSBTAP00000007948 Bos taurus (bovine) ENSCAFP00000017510 Canis familiaris (dog) cn04243 Cryptococcus neoformans (yeast-like fungus) CPIJ006749 Culex pipens (mosquito) ENSCPOP00000009385 Cavia porcellus (guinea pig) 183179 Chlamidomonas reinhardtii (green alga) 164650 Capitella spl (polychaete worm) 198197 Daphnia pulex (daphnia) ENSDARP00000022789 Danio rerio (zebra fish) ENSECAP00000009614 Equus caballus (horse) ENSGACP00000020646 Gymnopilus aculeatus (mushroom) ENSGALP00000013365 Gallus gallus (chicken) GL50803_7522 Giardia lamblia (flagellated protozoan) 82136 Hypsipyla robusta (cedar shoot borer) ENSP00000387086 Homo sapiens (human) ISCW005690-PA Ixodes scapularis (deer tick) 115834 Lottia gigantea (owl limpet) 16574 Monocosta brevicollis (choanoflagellate) ENSMODP00000018757 Monodelphis domestica (gray opossum) ENSMMUP00000022431 Macaca mulatta (rhesus monkey) ENSMUSP00000051935 Mus musculus (house mouse) 241916 Nematostella vectensis (starlet anemone) XP_001608265.1 Nasonia vitripennis (wasp) ENSOANP00000017152 Ornithorynchus anatinus (platypus) ENSORLP00000000149 Oryzias latipes (japanese killifish) LOC_Os11g21990.1 Oryza sativa (asian rice) PHUM000777-PA Pediculus humanus (human body louse) 228333 Physcomitrella patens (moss) ENSPPYP00000019911 Pongo pygmaeus (orangutan) 814507 Populus trichocarpa (black cottonwood) 814617 Populus trichocarpa (black cottonwood) ENSPTRP00000032377 Pan troglodytes (chimpanzee) ENSRNOP00000019486 Rattus norvegicus (norway rat) 4772058 Sorghum bicolor (sorghum) XP_792300.2 Strongylocentrotus purpuratus (purple sea urchin) 63688 Trichoplax adhaerens (metazoa) XP_973636.1 Tribolium castaneum (red flour beetle) ENSTNIP00000020310 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000014372 Takifugu rubripes (pufferfish Takifugu) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 40680 modMine - Data generated by the modENCODE project. • FBgn0250753 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10955 LH20303 ISCW005690 FBgn0067980 FBgn0224631 FBgn0211099 FBgn0191094 FBgn0165560 JGI_V11_198197 FBgn0075538 FBgn0159883 FBgn0146645 FBgn0124846 FBgn0103235 FBgn0097769 CPIJ006749 BGIBMGA008682 ACYPI006482 GB14569 AGAP002413 AAEL015512 AAEL012026 PB23726 PHUM450110 GLEAN_09915
Synonyms & Secondary IDs ( 26 )
Reported As
Symbol Synonym	anon-WO0172774.49   CG2922 (Le Mée et al., 2008, Lee et al., 2003, Huang et al., 2005, Quinones-Coello, 2007, Keleman et al., 2009.8.5, Muse et al., 2007, Ling and Salvaterra, 2011) CT7240 (Ceriani et al., 2002) Decp (Wan, 2000.11.30) ecp (Wang et al., 2006) eIF (Buszczak et al., 2007) eIF5 (Bottenberg et al., 2009) eIF-5C (Margulies et al., 2005, Jasper et al., 2002, Roote, 2004.7.20, Greenspan, 2003, Bellen et al., 2004, Dubnau et al., 2003, FlyBase, 1996-, Dubnau et al., 2003, Levis, 2002.6.24, Buszczak et al., 2007, Quinones-Coello, 2007, Gilchrist et al., 2008, Rehwinkel et al., 2005) eIf-5c (Ganguly-Fitzgerald et al., 2006) eiF-5C (Quinones-Coello, 2007) elF-5C (Ryder and Roote, 2004.11.10, Muse et al., 2007) elF5C (Sanchez-Soriano et al., 2009) elf-5C (Muse et al., 2007) exba (Arancio et al., 2010, Weake et al., 2011, Perkins et al., 2009.8.10, Devineni and Heberlein, 2009, Weake et al., 2009, Bartkowiak et al., 2010, Ling and Salvaterra, 2011) Exba (Lee et al., 2007) kra (Lee et al., 2007, Sanchez-Soriano et al., 2009, Bottenberg et al., 2009, Devineni and Heberlein, 2009) Kra (Lee et al., 2007) l(3)03022 (Spradling et al., 1999, Carrera et al., 1998, BDGP Project Members, 1994-1999, ) l(3)j9B6
Name Synonym	Drosophila eIF5C-containing protein (Wan, 2000.11.30) eukaryotic initiation factor 5C   extra bases (Lee et al., 2002) extra-bases (Lee et al., 2003, ) krasavietz (Huang et al., 2010, Yaksi and Wilson, 2010, Dubnau et al., 2003, Krashes et al., 2009, Devineni and Heberlein, 2009) Krasavietz (Lee et al., 2007, Sanchez-Soriano et al., 2009, Bottenberg et al., 2009, Seki et al., 2010) lethal (3) j9B6
Secondary FlyBase IDs
	FBgn0010791 FBgn0011418 FBgn0037346 FBgn0046382 FBgn0061514
References ( 64 )
Generate a list of	All references relating to this gene ( 64 )
List References by type	Research paper  ( 33 ) Supplementary material  ( 7 ) Review  ( 2 ) Personal communication to FlyBase  ( 11 ) Abstract  ( 2 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 4 ) Patent  ( 1 )
Recent research papers ( 11 )
	Acebes et al., 2011, J. Neurosci. 31(8): 2734--2745 Synapse loss in olfactory local interneurons modifies perception. [FBrf0213264] Kazama et al., 2011, J. Neurosci. 31(21): 7619--7630 Cell Death Triggers Olfactory Circuit Plasticity via Glial Signaling in Drosophila. [FBrf0213815] Ling and Salvaterra, 2011, PLoS ONE 6(3): e17762 Robust RT-qPCR Data Normalization: Validation and Selection of Internal Reference Genes during Post-Experimental Data Analysis. [FBrf0213272] Weake et al., 2011, Genes Dev. 25(14): 1499--1509 Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation. [FBrf0214372] Arancio et al., 2010, Genetics 185(1): 129--140 The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors. [FBrf0213976] Bartkowiak et al., 2010, Genes Dev. 24(20): 2303--2316 CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. [FBrf0212082] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Chou et al., 2010, Nat. Neurosci. 13(4): 439--449 Diversity and wiring variability of olfactory local interneurons in the Drosophila antennal lobe. [FBrf0210390] Huang et al., 2010, Neuron 67(6): 1021--1033 Functional connectivity and selective odor responses of excitatory local interneurons in Drosophila antennal lobe. [FBrf0211872] Seki et al., 2010, J. Neurophysiol. 104(2): 1007--1019 Physiological and morphological characterization of local interneurons in the Drosophila antennal lobe. [FBrf0211490] Yaksi and Wilson, 2010, Neuron 67(6): 1034--1047 Electrical coupling between olfactory glomeruli. [FBrf0211888] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...