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FB2021_04, released August 17, 2021

Gene: Dmel\kra

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General Information
Symbol
Dmel\kra
Species
D. melanogaster
Name
krasavietz
Annotation Symbol
CG2922
Feature Type
protein_coding_gene
FlyBase ID
FBgn0250753
Gene Model Status
Current
Stock Availability
19 publicly available
Gene Summary
krasavietz (kra) encodes a translational regulator that is able to interact with the translation initiation factor encoded by eIF2β. It is involved in axon guidance, long-term memory, and alcohol addiction. [Date last reviewed: 2019-03-14] (FlyBase Gene Snapshot)
All Summaries
Also Known As

exba, eIF-5C, l(3)03022, ECP, extra-bases

Key Links
Genomic Location
Cytogenetic map
83B4-83B5
Sequence location
3R:5,595,364..5,601,136 [-]
Recombination map
3-47.5
RefSeq locus
NT_033777 REGION:5595364..5601136
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (15 terms)
Molecular Function (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
enables protein binding
inferred from physical interaction with FLYBASE:shot; FB:FBgn0013733
(Lee et al., 2007)
inferred from physical interaction with FLYBASE:RpL5; FB:FBgn0064225
(Wang et al., 2006)
enables ribosomal small subunit binding
inferred from direct assay
(Lee et al., 2007)
enables ribosome binding
inferred from direct assay
(Wang et al., 2006)
enables translation initiation factor binding
inferred from physical interaction with FLYBASE:eIF2β; FB:FBgn0004926
(Lee et al., 2007)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (7 terms)
Terms Based on Experimental Evidence (7 terms)
CV Term
Evidence
References
involved_in axon midline choice point recognition
inferred from mutant phenotype
(Lee et al., 2007)
involved_in behavioral response to ethanol
inferred from mutant phenotype
(Berger et al., 2008)
involved_in long-term memory
inferred from mutant phenotype
(Akalal et al., 2011)
inferred from mutant phenotype
(assigned by UniProt )
(Dubnau et al., 2003)
involved_in negative regulation of translation
inferred from direct assay
(Lee et al., 2007)
involved_in oogenesis
inferred from mutant phenotype
(Lee et al., 2007)
involved_in ovarian follicle cell development
inferred from mutant phenotype
(Jia et al., 2015)
involved_in positive regulation of filopodium assembly
inferred from mutant phenotype
(Sanchez-Soriano et al., 2009)
inferred from genetic interaction with FLYBASE:shot; FB:FBgn0013733
(Sanchez-Soriano et al., 2009)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in long-term memory
traceable author statement
(Greenspan, 2003)
Cellular Component (4 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
located_in axonal growth cone
inferred from direct assay
(Sanchez-Soriano et al., 2009)
located_in cytoplasm
inferred from direct assay
(Wang et al., 2006)
located_in filopodium
inferred from direct assay
(Sanchez-Soriano et al., 2009)
located_in neuronal cell body
inferred from direct assay
(Sanchez-Soriano et al., 2009, Lee et al., 2007)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000368070
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the BZW family. (Q9VNE2)
Protein Signatures (InterPro)
Summaries
Gene Snapshot
krasavietz (kra) encodes a translational regulator that is able to interact with the translation initiation factor encoded by eIF2β. It is involved in axon guidance, long-term memory, and alcohol addiction. [Date last reviewed: 2019-03-14]
Protein Function (UniProtKB)
May be involved in memory formation.
(UniProt, Q9VNE2)
Gene Model and Products
Number of Transcripts
7
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\kra for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene
gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
kra-RA
FBtr0078744
NM_169074
2123
422
kra-RB
FBtr0078749
NM_169075
1847
422
kra-RC
FBtr0078746
NM_169076
1906
422
kra-RD
FBtr0078748
NM_169077
2026
422
kra-RE
FBtr0078750
NM_169078
1701
422
kra-RF
FBtr0078747
NM_169079
1776
422
kra-RG
FBtr0078745
NM_079514
1614
422
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
kra-PA
FBpp0078393
49.2
422
5.46
NP_730958
AAF51996
kra-PB
FBpp0078398
49.2
422
5.46
NP_730959
AAG22214
kra-PC
FBpp0078395
49.2
422
5.46
NP_730960
AAF51995
kra-PD
FBpp0078397
49.2
422
5.46
NP_730961
AAN13246
kra-PE
FBpp0078399
49.2
422
5.46
NP_730962
AAN13247
kra-PF
FBpp0078396
49.2
422
5.46
NP_730963
AAN13248
kra-PG
FBpp0078394
49.2
422
5.46
NP_524238
AAN13249
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

422 aa isoforms: kra-PA, kra-PB, kra-PC, kra-PD, kra-PE, kra-PF, kra-PG
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Nucleotide / Polypeptide Records
 
UniProt
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\kra using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 9 -- 10
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 11 -- 12
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 13 -- 16
organism | ubiquitous
(Fisher et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in axonal growth cone
inferred from direct assay
(Sanchez-Soriano et al., 2009)
located_in cytoplasm
inferred from direct assay
(Wang et al., 2006)
located_in filopodium
inferred from direct assay
(Sanchez-Soriano et al., 2009)
located_in neuronal cell body
inferred from direct assay
(Sanchez-Soriano et al., 2009, Lee et al., 2007)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\kra in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB
EMBL-EBI Single Cell Expression Atlas
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 35 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 8 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of kra
Transgenic constructs containing regulatory region of kra
Aberrations (Deficiencies and Duplications) ( 2 )
Inferred from experimentation ( 2 )
Gene disrupted in
Df(3R)ED5177
(Roote, 2004.7.20)
Df(3R)Exel6144
(Ryder, 2004.4.26)
Gene not disrupted in
Df(3R)ED5177
(Ryder and Roote, 2004.11.10)
Inferred from location ( 0 )
Alleles Representing Disease-Implicated Variants
Phenotypes
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (3)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\BZW1
14 of 15
Yes
Yes
Hsap\BZW2
12 of 15
No
Yes
Hsap\EIF5
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (3)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Bzw1
13 of 15
Yes
Yes
Mmus\Bzw2
12 of 15
No
Yes
Mmus\Eif5
1 of 15
No
No
Rattus norvegicus (Norway rat) (2)
Rnor\Bzw1
13 of 13
Yes
Yes
Rnor\Bzw2
12 of 13
No
Yes
Xenopus tropicalis (Western clawed frog) (3)
Xtro\bzw1
8 of 12
Yes
Yes
Xtro\bzw2
7 of 12
No
Yes
Xtro\eif4g2
1 of 12
No
No
Danio rerio (Zebrafish) (3)
Drer\bzw1a
14 of 15
Yes
Yes
Drer\bzw1b
12 of 15
No
Yes
Drer\bzw2
12 of 15
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\C37C3.2
1 of 15
Yes
No
Arabidopsis thaliana (thale-cress) (2)
Atha\AT1G65220
8 of 9
Yes
Yes
Atha\AT5G36230
8 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (1)
Scer\TIF5
1 of 15
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\tif225
1 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091908YO )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00010886
Drosophila simulans
Dsim\GD19602
Drosophila sechellia
Dsec\GM10614
Drosophila erecta
Dere\GG10932
Drosophila yakuba
Dyak\GE24159
Drosophila ananassae
Dana\GF20763
Drosophila pseudoobscura pseudoobscura
Dpse\GA15521
Drosophila persimilis
Dper\GL22291
Drosophila willistoni
Dwil\GK22654
Drosophila virilis
Dvir\GJ24012
Drosophila mojavensis
Dmoj\GI23920
Drosophila grimshawi
Dgri\GH17376
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091505HM )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17018533
Glossina morsitans
Tsetse fly
Gmor\GMOY001920
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_14223
Mayetiola destructor
Hessian fly
Mdes\Mdes002223
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL015512
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL012026
Anopheles darlingi
American malaria mosquito
Adar\ADAC001271
Anopheles gambiae
Malaria mosquito
Agam\AGAP002413
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ006749
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W06K2 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA008682
Danaus plexippus
Monarch butterfly
Dple\DPOGS215203-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL009664
Apis florea
Little honeybee
Aflo\2485214948
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP18224
Bombus terrestris
Buff-tailed bumblebee
Bter\15210743
Linepithema humile
Argentine ant
Lhum\LH20303
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:000a1b
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG002237
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_12646
Tribolium castaneum
Red flour beetle
Tcas\TC030783
Pediculus humanus
Human body louse
Phum\PHUM450110
Rhodnius prolixus
Kissing bug
Rpro\RPRC007462
Cimex lectularius
Bed bug
Clec\CLEC005867
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006482
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02743
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_16149
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X05VQ )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR006628
Ixodes scapularis
Black-legged tick
Isca\ISCW005690
Stegodyphus mimosarum
African social velvet spider
Smim\KFM79503.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM74754.1
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_198197
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G090E )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Bzw1
Gallus gallus
Domestic chicken
Ggal\BZW2
Gallus gallus
Domestic chicken
Ggal\BZW1
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (0)
No records found.
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
BZW1; basic leucine zipper and W2 domains 1
14 of 15
619252
      BZW2; basic leucine zipper and W2 domains 2
      12 of 15
      619275
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          Summary of Genetic Interactions
          esyN Network Diagram
          esyN Network Key:
          Suppression
          Enhancement
          View in Interactions Browser
          Please look at the allele data for full details of the genetic interactions
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          kra
          enhanceable
          shot
          (Lee et al., 2007)
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Kr
          suppressible
          kra
          (Carrera et al., 1998)
          robo1
          enhanceable
          kra
          (Lee et al., 2007)
          robo1|shot
          enhanceable
          kra
          (Lee et al., 2007)
          shot
          enhanceable
          kra
          (Lee et al., 2007)
          shot|sli
          enhanceable
          kra
          (Lee et al., 2007)
          sli
          enhanceable
          kra
          (Lee et al., 2007)
          External Data
          Linkouts
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          MIST (genetic) - An integrated Molecular Interaction Database
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          3R
          Recombination map
          3-47.5
          Cytogenetic map
          83B4-83B5
          Sequence location
          3R:5,595,364..5,601,136 [-]
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          83B4-83B5
          Left limit from in situ hybridisation (FBrf0067338) Right limit from in situ hybridisation (FBrf0067338)
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          83B4-83B4
          (Wan, 2000.11.30)
          83B4-83B5
          (determined by in situ hybridisation)
          (Spradling et al., 1999)
          83B4-83B2
          (determined by in situ hybridisation)
          (BDGP Project Members, 1994-1999)
          Experimentally Determined Recombination Data
          Location

          3-47.5

          (FlyBase, 2016)

          3-44.1

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (19)
          Genomic Clones (14)
           

          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

          cDNA Clones (391)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          DRSC - Results frm RNAi screens
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           

          polyclonal

          (Li et al., 2015, Lee et al., 2007, Wang et al., 2006)

          monoclonal

          (Wang et al., 2006)
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of

          Source for identity of: eIF-5C CG2922

          (FlyBase, 1996-)

          Source for identity of: kra exba

          (Lee et al., 2007)
          Source for database merge of

          Source for merge of: eIF-5C l(3)03022

          (Levis, 2002.6.24)

          Source for merge of: eIF-5C extra-bases

          (Lee et al., 2003)

          Source for merge of: exba l(3)j9B6

          (Lee et al., 2007)

          Source for merge of: eIF-5C anon-WO0172774.49

          (FlyBase, 1996-)
          Additional comments

          FlyBase curator comment: Originally named 'exba/extra bases' according to ADRC abstracts from the Lee group (FBrf0146421, FBrf0157123), but changed to 'kra/krasavietz' based on preference indicated in subsequently published research paper (FBrf0201378) by same group.

          (Lee et al., 2007)

          Source for identity of eIF-5C CG2922 was sequence comparison ( date:010210 ).

          (FlyBase, 1996-)

          Source for merge of eIF-5C anon-WO0172774.49 was sequence comparison ( date:051113 ).

          (FlyBase, 1996-)
          Other Comments

          dsRNA made from templates generated with primers directed against this gene.

          (Lee et al., 2007)

          exba has a role in long-term memory.

          (Dubnau et al., 2003)

          exba is required for lineage specification in the nervous system.

          (Lee et al., 2002)

          Mutants produce extra neurons.

          (Lee et al., 2002)
          Origin and Etymology
          Discoverer

          L. and Y. Jan.

          Etymology
          Identification
          External Crossreferences and Linkouts ( 78 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
          Other crossreferences
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DRscDB
          EMBL-EBI Single Cell Expression Atlas
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          FlyMine - An integrated database for Drosophila genomics
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL
          modMine - A data warehouse for the modENCODE project
          Linkouts
          ApoDroso - Functional genomic database for photoreceptor development, survival and function
          BioGRID - A database of protein and genetic interactions.
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          MIST (genetic) - An integrated Molecular Interaction Database
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Synonyms and Secondary IDs (36)
          Reported As
          Symbol Synonym
          5MP
          (Kozel et al., 2016)
          CG2922
          (Kolkhof et al., 2017, Schwartz et al., 2016, Hosono et al., 2015, Ling and Salvaterra, 2011, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Le Mée et al., 2008, Muse et al., 2007, Quinones-Coello, 2007, Huang et al., 2005, Lee et al., 2003)
          CT7240
          (Ceriani et al., 2002)
          Decp
          (Wan, 2000.11.30)
          ECP
          (Wang et al., 2014, Zhao et al., 2012, Wang et al., 2006)
          Ecp
          (Li et al., 2015)
          Exba
          (Lee et al., 2007)
          Kra
          (Kaufman et al., 2020, Voelzmann et al., 2017, Carvajal-Gonzalez et al., 2016, Kaun et al., 2012, Das et al., 2010, Lee et al., 2007)
          anon-WO0172774.49
          chr3R:1423015..1423173
          (Will et al., 2013)
          eIF
          (Buszczak et al., 2007)
          eIF-5C
          (Berger et al., 2008, Gilchrist et al., 2008, Buszczak et al., 2007, Quinones-Coello, 2007, Margulies et al., 2005, Rehwinkel et al., 2005, Bellen et al., 2004, Roote, 2004.7.20, Dubnau et al., 2003, Dubnau et al., 2003, Greenspan, 2003, Jasper et al., 2002, Levis, 2002.6.24, FlyBase, 1996-)
          eIF-5c
          (Hartmann et al., 2011)
          eIF5
          (Yu et al., 2016, Bottenberg et al., 2009)
          eIF5C
          (Bradley et al., 2012)
          eIF5c
          (Goodman et al., 2019, Devineni and Heberlein, 2010)
          eIf-5c
          (Ganguly-Fitzgerald et al., 2006)
          ecp
          (Wang et al., 2006)
          eiF-5C
          (Quinones-Coello, 2007)
          elF-5C
          (Muse et al., 2007, Ryder and Roote, 2004.11.10)
          elF5C
          (Sanchez-Soriano et al., 2009)
          elf-5C
          (Muse et al., 2007)
          exba
          (Deshpande et al., 2019, Stegeman et al., 2016, Jia et al., 2015, Ashwal-Fluss et al., 2014, Robinson and Atkinson, 2013, Sen et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Winbush et al., 2012, Chung et al., 2011, Ling and Salvaterra, 2011, Weake et al., 2011, Arancio et al., 2010, Bartkowiak et al., 2010, Devineni and Heberlein, 2010, Devineni and Heberlein, 2009, Perkins et al., 2009.8.10, Weake et al., 2009, Berger et al., 2008, Marygold et al., 2007)
          exba/kra
          (Angrisani et al., 2015)
          kra
          (Park et al., 2017, Ables et al., 2016, Clandinin and Owens, 2016-, Kaun et al., 2012, Awofala, 2011, Bottenberg et al., 2009, Devineni and Heberlein, 2009, Sanchez-Soriano et al., 2009, Lee et al., 2007, Lee et al., 2007)
          l(3)03022
          (Spradling et al., 1999, Carrera et al., 1998, BDGP Project Members, 1994-1999)
          l(3)j9B6
          Name Synonyms
          Drosophila eIF5C-containing protein
          (Wan, 2000.11.30)
          Krasavietz
          (Marygold et al., 2017, Das et al., 2010, Devineni and Heberlein, 2010, Seki et al., 2010, Bottenberg et al., 2009, Sanchez-Soriano et al., 2009, Lee et al., 2007)
          eIF5-mimic protein
          (Kozel et al., 2016)
          eukaryotic initiation factor 5C
          extra bases
          (Lee et al., 2002)
          extra bses
          (Hartmann et al., 2011)
          extra-bases
          (Lee et al., 2003)
          krasavietz
          (Carvajal-Gonzalez et al., 2016, Kaun et al., 2012, Awofala, 2011, Hartmann et al., 2011, Huang et al., 2010, Yaksi and Wilson, 2010, Devineni and Heberlein, 2009, Krashes et al., 2009, Berger et al., 2008, Dubnau et al., 2003)
          lethal (3) j9B6
          Secondary FlyBase IDs
          • FBgn0061514
          • FBgn0046382
          • FBgn0010791
          • FBgn0037346
          • FBgn0011418
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          References (120)