Gene Dmel\CG4169

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General Information

Symbol

Dmel\CG4169

Species

D. melanogaster

Name

Annotation symbol

CG4169

Feature type

protein_coding_gene

FlyBase ID

FBgn0250814

Gene Model Status

Current

Stock availability

4 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

73A10-73A10

Sequence location

3L:16,577,224..16,579,211 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG4169 (FBgn0250814). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ubiquinol-cytochrome-c reductase activity. Based on sequence similarity, it is predicted to be involved in the biological process: mitochondrial electron transport, ubiquinol to cytochrome c. 4 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Metalloenzyme, LuxS/M16 peptidase-like; Peptidase M16 domain; Peptidase M16, C-terminal domain; Peptidase M16, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval fat body, larval trachea, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1624439_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG4169. Gene sequence location is 3L:16577224..16579211.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

73A10-73A10

Limits computationally determined from genome sequence between P{lacW}l(3)j10E8^j10E8&P{PZ}l(3)10532¹⁰⁵³² and P{PZ}Baldspot⁰²²⁸¹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG4169 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.45

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG4169-RA

FBtr0075309

NM_140648

1686

440

CG4169-RB

FBtr0331557

NM_001275026

1537

440

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG4169-PA

FBpp0075069

45.4

440

9.95

NP_648905

AAF49444

CG4169-PB

FBpp0303947

45.4

440

9.95

NP_001261955

AGB94648

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Peptidase M16, C-terminal domain (IPR007863)

Peptidase M16, N-terminal (IPR011765)

Peptidase M16 domain (IPR011237)

Metalloenzyme, LuxS/M16 peptidase-like (IPR011249)

MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins

•

MTDROME04169

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9VV75

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

dorsal pharyngeal muscle primordium

(Fisher et al., 2012)

fat body primordium

(Fisher et al., 2012)

Comment:reported as fat body specific anlage

organism | ubiquitous

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

somatic muscle primordium

(Fisher et al., 2012)

Comment:reported as muscle system primordium

visceral muscle primordium

(Fisher et al., 2012)

Comment:reported as muscle system primordium

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 13 -- 16

dorsal pharyngeal muscle

(Fisher et al., 2012)

embryonic anal pad

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic Malpighian tubule

(Fisher et al., 2012)

embryonic proventriculus

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

embryonic/larval muscle system

(Fisher et al., 2012)

embryonic/larval somatic muscle

(Fisher et al., 2012)

embryonic/larval visceral muscle

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Dorus et al., 2006, Wasbrough et al., 2010)

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

lipid particle

inferred from direct assay

(Beller et al., 2006, Cermelli et al., 2006)

microtubule associated complex

inferred from direct assay

(Hughes et al., 2008)

mitochondrion

inferred from direct assay

(Alonso et al., 2005)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval fat body, larval trachea, adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		1260
Larval Hindgut		1563.6
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		1133.275
Adult Head		1273.3
Adult Eye		1511
Adult Brain		1136
Adult Thoracic-Abdominal Ganglion		1360.7
Adult Crop		1134.8
Adult Midgut		1055
Adult Hindgut		1788.3
Adult Malpighian Tubules		1882.7
Adult Fat Body		1573.2
Adult Salivary Gland		2049.2
Adult Heart		1888.3
Adult VirginFemale Spermatheca		1460
Adult InseminatedFemale Spermatheca		1282.4
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		3027.8
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		(1260)
Larval Hindgut		(1563.6)
Larval Malpighian Tubules		(659.6)
Larval Fat Body		296.9
Larval Salivary Gland		(701)
Larval Trachea		498.975
Larval Carcass		(1133.275)
Adult Head		(1273.3)
Adult Eye		(1511)
Adult Brain		(1136)
Adult Thoracic-Abdominal Ganglion		(1360.7)
Adult Crop		(1134.8)
Adult Midgut		(1055)
Adult Hindgut		(1788.3)
Adult Malpighian Tubules		(1882.7)
Adult Fat Body		(1573.2)
Adult Salivary Gland		(2049.2)
Adult Heart		(1888.3)
Adult VirginFemale Spermatheca		(1460)
Adult InseminatedFemale Spermatheca		(1282.4)
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		(590.9)
Adult Carcass		(3027.8)
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		(1260)
Larval Hindgut		(1563.6)
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		(1133.275)
Adult Head		(1273.3)
Adult Eye		(1511)
Adult Brain		(1136)
Adult Thoracic-Abdominal Ganglion		(1360.7)
Adult Crop		(1134.8)
Adult Midgut		1055
Adult Hindgut		(1788.3)
Adult Malpighian Tubules		(1882.7)
Adult Fat Body		(1573.2)
Adult Salivary Gland		(2049.2)
Adult Heart		(1888.3)
Adult VirginFemale Spermatheca		(1460)
Adult InseminatedFemale Spermatheca		(1282.4)
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		(3027.8)
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		1260
Larval Hindgut		1563.6
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		1133.275
Adult Head		1273.3
Adult Eye		1511
Adult Brain		1136
Adult Thoracic-Abdominal Ganglion		1360.7
Adult Crop		1134.8
Adult Midgut		1055
Adult Hindgut		1788.3
Adult Malpighian Tubules		1882.7
Adult Fat Body		1573.2
Adult Salivary Gland		2049.2
Adult Heart		1888.3
Adult VirginFemale Spermatheca		1460
Adult InseminatedFemale Spermatheca		1282.4
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		3027.8
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		1260
Larval Hindgut		1563.6
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		1133.275
Adult Head		1273.3
Adult Eye		1511
Adult Brain		1136
Adult Thoracic-Abdominal Ganglion		1360.7
Adult Crop		1134.8
Adult Midgut		1055
Adult Hindgut		1788.3
Adult Malpighian Tubules		1882.7
Adult Fat Body		1573.2
Adult Salivary Gland		2049.2
Adult Heart		1888.3
Adult VirginFemale Spermatheca		1460
Adult InseminatedFemale Spermatheca		1282.4
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		3027.8
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		(1260)
Larval Hindgut		(1563.6)
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		(1133.275)
Adult Head		(1273.3)
Adult Eye		(1511)
Adult Brain		(1136)
Adult Thoracic-Abdominal Ganglion		(1360.7)
Adult Crop		(1134.8)
Adult Midgut		(1055)
Adult Hindgut		(1788.3)
Adult Malpighian Tubules		(1882.7)
Adult Fat Body		(1573.2)
Adult Salivary Gland		(2049.2)
Adult Heart		(1888.3)
Adult VirginFemale Spermatheca		(1460)
Adult InseminatedFemale Spermatheca		(1282.4)
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		(3027.8)
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		1260
Larval Hindgut		1563.6
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		1133.275
Adult Head		1273.3
Adult Eye		1511
Adult Brain		1136
Adult Thoracic-Abdominal Ganglion		1360.7
Adult Crop		1134.8
Adult Midgut		1055
Adult Hindgut		(1788.3)
Adult Malpighian Tubules		(1882.7)
Adult Fat Body		1573.2
Adult Salivary Gland		(2049.2)
Adult Heart		(1888.3)
Adult VirginFemale Spermatheca		1460
Adult InseminatedFemale Spermatheca		1282.4
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		(3027.8)
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		499.55
Larval Midgut		1260
Larval Hindgut		1563.6
Larval Malpighian Tubules		659.6
Larval Fat Body		296.9
Larval Salivary Gland		701
Larval Trachea		498.975
Larval Carcass		1133.275
Adult Head		1273.3
Adult Eye		1511
Adult Brain		1136
Adult Thoracic-Abdominal Ganglion		1360.7
Adult Crop		1134.8
Adult Midgut		1055
Adult Hindgut		1788.3
Adult Malpighian Tubules		1882.7
Adult Fat Body		1573.2
Adult Salivary Gland		2049.2
Adult Heart		1888.3
Adult VirginFemale Spermatheca		1460
Adult InseminatedFemale Spermatheca		1282.4
Adult Ovary		502
Adult Testis		417.5
Adult Male Accessory Gland		590.9
Adult Carcass		3027.8
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	1273.3
NA	Eye	1511
NA	Brain	1136
499.55	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	1360.7
NA	Crop	1134.8
1260	Midgut	1055
1563.6	Hindgut	1788.3
659.6	Malpighian Tubules	1882.7
296.9	Fat Body	1573.2
701	Salivary Gland	2049.2
NA	Heart	1888.3
498.975	Trachea	NA
NA	VirginFemale Spermatheca	1460
NA	InseminatedFemale Spermatheca	1282.4
NA	Ovary	502
NA	Testis	417.5
NA	Male Accessory Gland	590.9
1133.275	Carcass	3027.8

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		123
central nervous system, larvae L3		56
central nervous system, pupae P8		67
head, virgin 1-day female		225
head, virgin 4-day female		143
head, virgin 20-day female		162
head, mated 1-day female		172
head, mated 4-day female		95
head, mated 20-day female		142
head, mated 1-day male		280
head, mated 4-day male		142
head, mated 20-day male		161
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		56
digestive system, 1-day adult		213
digestive system, 4-day adult		122
digestive system, 20-day adult		144
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		53
carcass, larvae L3 wandering		50
carcass, 1-day adult		574
carcass, 4-day adult		270
carcass, 20-day adult		265
ovary, virgin 4-day female		92
ovary, mated 4-day female		80
testis, mated 4-day male		264
accessory gland, mated 4-day male		116
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(123)
central nervous system, larvae L3		(56)
central nervous system, pupae P8		(67)
head, virgin 1-day female		(225)
head, virgin 4-day female		(143)
head, virgin 20-day female		(162)
head, mated 1-day female		(172)
head, mated 4-day female		(95)
head, mated 20-day female		(142)
head, mated 1-day male		(280)
head, mated 4-day male		(142)
head, mated 20-day male		(161)
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		(56)
digestive system, 1-day adult		(213)
digestive system, 4-day adult		(122)
digestive system, 20-day adult		(144)
fat body, larvae L3 wandering		(32)
fat body, white prepupae		25
fat body, pupae P8		(53)
carcass, larvae L3 wandering		(50)
carcass, 1-day adult		(574)
carcass, 4-day adult		(270)
carcass, 20-day adult		(265)
ovary, virgin 4-day female		(92)
ovary, mated 4-day female		(80)
testis, mated 4-day male		(264)
accessory gland, mated 4-day male		(116)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(123)
central nervous system, larvae L3		56
central nervous system, pupae P8		67
head, virgin 1-day female		(225)
head, virgin 4-day female		(143)
head, virgin 20-day female		(162)
head, mated 1-day female		(172)
head, mated 4-day female		95
head, mated 20-day female		(142)
head, mated 1-day male		(280)
head, mated 4-day male		(142)
head, mated 20-day male		(161)
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		56
digestive system, 1-day adult		(213)
digestive system, 4-day adult		(122)
digestive system, 20-day adult		(144)
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		53
carcass, larvae L3 wandering		50
carcass, 1-day adult		(574)
carcass, 4-day adult		(270)
carcass, 20-day adult		(265)
ovary, virgin 4-day female		92
ovary, mated 4-day female		80
testis, mated 4-day male		(264)
accessory gland, mated 4-day male		(116)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		123
central nervous system, larvae L3		56
central nervous system, pupae P8		67
head, virgin 1-day female		225
head, virgin 4-day female		143
head, virgin 20-day female		162
head, mated 1-day female		172
head, mated 4-day female		95
head, mated 20-day female		142
head, mated 1-day male		280
head, mated 4-day male		142
head, mated 20-day male		161
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		56
digestive system, 1-day adult		213
digestive system, 4-day adult		122
digestive system, 20-day adult		144
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		53
carcass, larvae L3 wandering		50
carcass, 1-day adult		574
carcass, 4-day adult		270
carcass, 20-day adult		265
ovary, virgin 4-day female		92
ovary, mated 4-day female		80
testis, mated 4-day male		264
accessory gland, mated 4-day male		116
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		123
central nervous system, larvae L3		56
central nervous system, pupae P8		67
head, virgin 1-day female		225
head, virgin 4-day female		143
head, virgin 20-day female		162
head, mated 1-day female		172
head, mated 4-day female		95
head, mated 20-day female		142
head, mated 1-day male		280
head, mated 4-day male		142
head, mated 20-day male		161
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		56
digestive system, 1-day adult		213
digestive system, 4-day adult		122
digestive system, 20-day adult		144
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		53
carcass, larvae L3 wandering		50
carcass, 1-day adult		574
carcass, 4-day adult		270
carcass, 20-day adult		265
ovary, virgin 4-day female		92
ovary, mated 4-day female		80
testis, mated 4-day male		264
accessory gland, mated 4-day male		116
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(123)
central nervous system, larvae L3		(56)
central nervous system, pupae P8		(67)
head, virgin 1-day female		(225)
head, virgin 4-day female		(143)
head, virgin 20-day female		(162)
head, mated 1-day female		(172)
head, mated 4-day female		(95)
head, mated 20-day female		(142)
head, mated 1-day male		(280)
head, mated 4-day male		(142)
head, mated 20-day male		(161)
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		(56)
digestive system, 1-day adult		(213)
digestive system, 4-day adult		(122)
digestive system, 20-day adult		(144)
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		(53)
carcass, larvae L3 wandering		(50)
carcass, 1-day adult		(574)
carcass, 4-day adult		(270)
carcass, 20-day adult		(265)
ovary, virgin 4-day female		(92)
ovary, mated 4-day female		(80)
testis, mated 4-day male		(264)
accessory gland, mated 4-day male		(116)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		123
central nervous system, larvae L3		56
central nervous system, pupae P8		67
head, virgin 1-day female		(225)
head, virgin 4-day female		143
head, virgin 20-day female		(162)
head, mated 1-day female		(172)
head, mated 4-day female		95
head, mated 20-day female		142
head, mated 1-day male		(280)
head, mated 4-day male		142
head, mated 20-day male		(161)
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		56
digestive system, 1-day adult		(213)
digestive system, 4-day adult		122
digestive system, 20-day adult		(144)
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		53
carcass, larvae L3 wandering		50
carcass, 1-day adult		(574)
carcass, 4-day adult		(270)
carcass, 20-day adult		(265)
ovary, virgin 4-day female		92
ovary, mated 4-day female		80
testis, mated 4-day male		(264)
accessory gland, mated 4-day male		116
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		123
central nervous system, larvae L3		56
central nervous system, pupae P8		67
head, virgin 1-day female		225
head, virgin 4-day female		143
head, virgin 20-day female		162
head, mated 1-day female		172
head, mated 4-day female		95
head, mated 20-day female		142
head, mated 1-day male		280
head, mated 4-day male		142
head, mated 20-day male		161
salivary gland, larvae L3 wandering		10
salivary gland, white prepupae		24
digestive system, larvae L3 wandering		56
digestive system, 1-day adult		213
digestive system, 4-day adult		122
digestive system, 20-day adult		144
fat body, larvae L3 wandering		32
fat body, white prepupae		25
fat body, pupae P8		53
carcass, larvae L3 wandering		50
carcass, 1-day adult		574
carcass, 4-day adult		270
carcass, 20-day adult		265
ovary, virgin 4-day female		92
ovary, mated 4-day female		80
testis, mated 4-day male		264
accessory gland, mated 4-day male		116
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		142
embryo 02-04hr		44
embryo 04-06hr		77
embryo 06-08hr		105
embryo 08-10hr		104
embryo 10-12hr		230
embryo 12-14hr		121
embryo 14-16hr		266
embryo 16-18hr		257
embryo 18-20hr		406
embryo 20-22hr		439
embryo 22-24hr		327
larva L1		511
larva L2		459
larva L3 12hr old		493
larva L3 puffstage 1-2		186
larva L3 puffstage 3-6		108
larva L3 puffstage 7-9		71
white prepupae new		66
white prepupae 12hr		64
white prepupae 24hr		79
pupae 2d postWPP		160
pupae 3d postWPP		461
pupae 4d postWPP		868
adult male 01day		849
adult male 05day		732
adult male 30day		384
adult female 01day		759
adult female 05day		262
adult female 30day		220
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(142)
embryo 02-04hr		(44)
embryo 04-06hr		(77)
embryo 06-08hr		(105)
embryo 08-10hr		(104)
embryo 10-12hr		(230)
embryo 12-14hr		(121)
embryo 14-16hr		(266)
embryo 16-18hr		(257)
embryo 18-20hr		(406)
embryo 20-22hr		(439)
embryo 22-24hr		(327)
larva L1		(511)
larva L2		(459)
larva L3 12hr old		(493)
larva L3 puffstage 1-2		(186)
larva L3 puffstage 3-6		(108)
larva L3 puffstage 7-9		(71)
white prepupae new		(66)
white prepupae 12hr		(64)
white prepupae 24hr		(79)
pupae 2d postWPP		(160)
pupae 3d postWPP		(461)
pupae 4d postWPP		(868)
adult male 01day		(849)
adult male 05day		(732)
adult male 30day		(384)
adult female 01day		(759)
adult female 05day		(262)
adult female 30day		(220)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(142)
embryo 02-04hr		44
embryo 04-06hr		77
embryo 06-08hr		105
embryo 08-10hr		104
embryo 10-12hr		(230)
embryo 12-14hr		(121)
embryo 14-16hr		(266)
embryo 16-18hr		(257)
embryo 18-20hr		(406)
embryo 20-22hr		(439)
embryo 22-24hr		(327)
larva L1		(511)
larva L2		(459)
larva L3 12hr old		(493)
larva L3 puffstage 1-2		(186)
larva L3 puffstage 3-6		(108)
larva L3 puffstage 7-9		71
white prepupae new		66
white prepupae 12hr		64
white prepupae 24hr		79
pupae 2d postWPP		(160)
pupae 3d postWPP		(461)
pupae 4d postWPP		(868)
adult male 01day		(849)
adult male 05day		(732)
adult male 30day		(384)
adult female 01day		(759)
adult female 05day		(262)
adult female 30day		(220)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		142
embryo 02-04hr		44
embryo 04-06hr		77
embryo 06-08hr		105
embryo 08-10hr		104
embryo 10-12hr		230
embryo 12-14hr		121
embryo 14-16hr		266
embryo 16-18hr		257
embryo 18-20hr		406
embryo 20-22hr		439
embryo 22-24hr		327
larva L1		511
larva L2		459
larva L3 12hr old		493
larva L3 puffstage 1-2		186
larva L3 puffstage 3-6		108
larva L3 puffstage 7-9		71
white prepupae new		66
white prepupae 12hr		64
white prepupae 24hr		79
pupae 2d postWPP		160
pupae 3d postWPP		461
pupae 4d postWPP		868
adult male 01day		849
adult male 05day		732
adult male 30day		384
adult female 01day		759
adult female 05day		262
adult female 30day		220
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		142
embryo 02-04hr		44
embryo 04-06hr		77
embryo 06-08hr		105
embryo 08-10hr		104
embryo 10-12hr		230
embryo 12-14hr		121
embryo 14-16hr		266
embryo 16-18hr		257
embryo 18-20hr		406
embryo 20-22hr		439
embryo 22-24hr		327
larva L1		511
larva L2		459
larva L3 12hr old		493
larva L3 puffstage 1-2		186
larva L3 puffstage 3-6		108
larva L3 puffstage 7-9		71
white prepupae new		66
white prepupae 12hr		64
white prepupae 24hr		79
pupae 2d postWPP		160
pupae 3d postWPP		461
pupae 4d postWPP		868
adult male 01day		849
adult male 05day		732
adult male 30day		384
adult female 01day		759
adult female 05day		262
adult female 30day		220
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(142)
embryo 02-04hr		(44)
embryo 04-06hr		(77)
embryo 06-08hr		(105)
embryo 08-10hr		(104)
embryo 10-12hr		(230)
embryo 12-14hr		(121)
embryo 14-16hr		(266)
embryo 16-18hr		(257)
embryo 18-20hr		(406)
embryo 20-22hr		(439)
embryo 22-24hr		(327)
larva L1		(511)
larva L2		(459)
larva L3 12hr old		(493)
larva L3 puffstage 1-2		(186)
larva L3 puffstage 3-6		(108)
larva L3 puffstage 7-9		(71)
white prepupae new		(66)
white prepupae 12hr		(64)
white prepupae 24hr		(79)
pupae 2d postWPP		(160)
pupae 3d postWPP		(461)
pupae 4d postWPP		(868)
adult male 01day		(849)
adult male 05day		(732)
adult male 30day		(384)
adult female 01day		(759)
adult female 05day		(262)
adult female 30day		(220)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		142
embryo 02-04hr		44
embryo 04-06hr		77
embryo 06-08hr		105
embryo 08-10hr		104
embryo 10-12hr		(230)
embryo 12-14hr		121
embryo 14-16hr		(266)
embryo 16-18hr		(257)
embryo 18-20hr		(406)
embryo 20-22hr		(439)
embryo 22-24hr		(327)
larva L1		(511)
larva L2		(459)
larva L3 12hr old		(493)
larva L3 puffstage 1-2		(186)
larva L3 puffstage 3-6		108
larva L3 puffstage 7-9		71
white prepupae new		66
white prepupae 12hr		64
white prepupae 24hr		79
pupae 2d postWPP		(160)
pupae 3d postWPP		(461)
pupae 4d postWPP		(868)
adult male 01day		(849)
adult male 05day		(732)
adult male 30day		(384)
adult female 01day		(759)
adult female 05day		(262)
adult female 30day		(220)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		142
embryo 02-04hr		44
embryo 04-06hr		77
embryo 06-08hr		105
embryo 08-10hr		104
embryo 10-12hr		230
embryo 12-14hr		121
embryo 14-16hr		266
embryo 16-18hr		257
embryo 18-20hr		406
embryo 20-22hr		439
embryo 22-24hr		327
larva L1		511
larva L2		459
larva L3 12hr old		493
larva L3 puffstage 1-2		186
larva L3 puffstage 3-6		108
larva L3 puffstage 7-9		71
white prepupae new		66
white prepupae 12hr		64
white prepupae 24hr		79
pupae 2d postWPP		160
pupae 3d postWPP		461
pupae 4d postWPP		868
adult male 01day		849
adult male 05day		732
adult male 30day		384
adult female 01day		759
adult female 05day		262
adult female 30day		220
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		198
Schneider line 2 Sg4		344
embryonic 1182-4H		89
embryonic GM2		96
embryonic Kc167		83
embryonic S1		206
embryonic S3		145
leg disc CME L1		225
wing disc CME-W2		112
wing disc ML-DmD8		68
wing disc ML-DmD9		153
wing disc ML-DmD16-c3		112
wing disc ML-DmD21		273
wing disc ML-DmD32		112
haltere disc ML-DmD17-c3		141
eye-antennal disc ML-DmD11		345
antennal disc ML-DmD20-c5		161
mixed discs ML-DmD4-c1		87
CNS ML-DmBG1-c1		140
CNS ML-DmBG2-c2		63
tumorous blood cells mbn2		87
ovary fGS/OSS		80
ovary OSC		92
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(198)
Schneider line 2 Sg4		(344)
embryonic 1182-4H		(89)
embryonic GM2		(96)
embryonic Kc167		(83)
embryonic S1		(206)
embryonic S3		(145)
leg disc CME L1		(225)
wing disc CME-W2		(112)
wing disc ML-DmD8		(68)
wing disc ML-DmD9		(153)
wing disc ML-DmD16-c3		(112)
wing disc ML-DmD21		(273)
wing disc ML-DmD32		(112)
haltere disc ML-DmD17-c3		(141)
eye-antennal disc ML-DmD11		(345)
antennal disc ML-DmD20-c5		(161)
mixed discs ML-DmD4-c1		(87)
CNS ML-DmBG1-c1		(140)
CNS ML-DmBG2-c2		(63)
tumorous blood cells mbn2		(87)
ovary fGS/OSS		(80)
ovary OSC		(92)
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(198)
Schneider line 2 Sg4		(344)
embryonic 1182-4H		89
embryonic GM2		96
embryonic Kc167		83
embryonic S1		(206)
embryonic S3		(145)
leg disc CME L1		(225)
wing disc CME-W2		(112)
wing disc ML-DmD8		68
wing disc ML-DmD9		(153)
wing disc ML-DmD16-c3		(112)
wing disc ML-DmD21		(273)
wing disc ML-DmD32		(112)
haltere disc ML-DmD17-c3		(141)
eye-antennal disc ML-DmD11		(345)
antennal disc ML-DmD20-c5		(161)
mixed discs ML-DmD4-c1		87
CNS ML-DmBG1-c1		(140)
CNS ML-DmBG2-c2		63
tumorous blood cells mbn2		87
ovary fGS/OSS		80
ovary OSC		92
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		198
Schneider line 2 Sg4		344
embryonic 1182-4H		89
embryonic GM2		96
embryonic Kc167		83
embryonic S1		206
embryonic S3		145
leg disc CME L1		225
wing disc CME-W2		112
wing disc ML-DmD8		68
wing disc ML-DmD9		153
wing disc ML-DmD16-c3		112
wing disc ML-DmD21		273
wing disc ML-DmD32		112
haltere disc ML-DmD17-c3		141
eye-antennal disc ML-DmD11		345
antennal disc ML-DmD20-c5		161
mixed discs ML-DmD4-c1		87
CNS ML-DmBG1-c1		140
CNS ML-DmBG2-c2		63
tumorous blood cells mbn2		87
ovary fGS/OSS		80
ovary OSC		92
ovary OSS		23
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		198
Schneider line 2 Sg4		344
embryonic 1182-4H		89
embryonic GM2		96
embryonic Kc167		83
embryonic S1		206
embryonic S3		145
leg disc CME L1		225
wing disc CME-W2		112
wing disc ML-DmD8		68
wing disc ML-DmD9		153
wing disc ML-DmD16-c3		112
wing disc ML-DmD21		273
wing disc ML-DmD32		112
haltere disc ML-DmD17-c3		141
eye-antennal disc ML-DmD11		345
antennal disc ML-DmD20-c5		161
mixed discs ML-DmD4-c1		87
CNS ML-DmBG1-c1		140
CNS ML-DmBG2-c2		63
tumorous blood cells mbn2		87
ovary fGS/OSS		80
ovary OSC		92
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(198)
Schneider line 2 Sg4		(344)
embryonic 1182-4H		(89)
embryonic GM2		(96)
embryonic Kc167		(83)
embryonic S1		(206)
embryonic S3		(145)
leg disc CME L1		(225)
wing disc CME-W2		(112)
wing disc ML-DmD8		(68)
wing disc ML-DmD9		(153)
wing disc ML-DmD16-c3		(112)
wing disc ML-DmD21		(273)
wing disc ML-DmD32		(112)
haltere disc ML-DmD17-c3		(141)
eye-antennal disc ML-DmD11		(345)
antennal disc ML-DmD20-c5		(161)
mixed discs ML-DmD4-c1		(87)
CNS ML-DmBG1-c1		(140)
CNS ML-DmBG2-c2		(63)
tumorous blood cells mbn2		(87)
ovary fGS/OSS		(80)
ovary OSC		(92)
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(198)
Schneider line 2 Sg4		(344)
embryonic 1182-4H		89
embryonic GM2		96
embryonic Kc167		83
embryonic S1		(206)
embryonic S3		(145)
leg disc CME L1		(225)
wing disc CME-W2		112
wing disc ML-DmD8		68
wing disc ML-DmD9		(153)
wing disc ML-DmD16-c3		112
wing disc ML-DmD21		(273)
wing disc ML-DmD32		112
haltere disc ML-DmD17-c3		141
eye-antennal disc ML-DmD11		(345)
antennal disc ML-DmD20-c5		(161)
mixed discs ML-DmD4-c1		87
CNS ML-DmBG1-c1		140
CNS ML-DmBG2-c2		63
tumorous blood cells mbn2		87
ovary fGS/OSS		80
ovary OSC		92
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		198
Schneider line 2 Sg4		344
embryonic 1182-4H		89
embryonic GM2		96
embryonic Kc167		83
embryonic S1		206
embryonic S3		145
leg disc CME L1		225
wing disc CME-W2		112
wing disc ML-DmD8		68
wing disc ML-DmD9		153
wing disc ML-DmD16-c3		112
wing disc ML-DmD21		273
wing disc ML-DmD32		112
haltere disc ML-DmD17-c3		141
eye-antennal disc ML-DmD11		345
antennal disc ML-DmD20-c5		161
mixed discs ML-DmD4-c1		87
CNS ML-DmBG1-c1		140
CNS ML-DmBG2-c2		63
tumorous blood cells mbn2		87
ovary fGS/OSS		80
ovary OSC		92
ovary OSS		23
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		98
cold shock, 4-day adult		68
heat shock, 4-day adult		253
Cadmium 50 mM 6 hrs, larvae L3		300
Cadmium 50 mM 12 hrs, larvae L3		70
Cadmium 50 mM 48 hrs, 4-day adult		192
Cadmium 100 mM 48 hrs, 4-day adult		130
Copper 0.5 mM 12 hrs, larvae L3		121
Copper 15 mM 48 hrs, 4-day adult		58
Zinc 5 mM 12 hrs, larvae L3		82
Zinc 4.5 mM 48 hrs, 4-day adult		83
Ethanol 2.5% 3 hrs, larvae L3		238
Ethanol 5% 3 hrs, larvae L3		218
Ethanol 10% 3 hrs, larvae L3		264
Caffeine 1.5 mg/ml 4 hrs, larvae L3		142
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		118
Caffeine 25 mg/ml 48 hrs, 4-day adult		75
Paraquat 5 mM 48 hrs, 4-day adult		232
Paraquat 10 mM 48 hrs, 4-day adult		294
Rotenone 2 μg 12 hrs, larvae L3		229
Rotenone 8 μg 12 hrs, larvae L3		361
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(98)
cold shock, 4-day adult		(68)
heat shock, 4-day adult		(253)
Cadmium 50 mM 6 hrs, larvae L3		(300)
Cadmium 50 mM 12 hrs, larvae L3		(70)
Cadmium 50 mM 48 hrs, 4-day adult		(192)
Cadmium 100 mM 48 hrs, 4-day adult		(130)
Copper 0.5 mM 12 hrs, larvae L3		(121)
Copper 15 mM 48 hrs, 4-day adult		(58)
Zinc 5 mM 12 hrs, larvae L3		(82)
Zinc 4.5 mM 48 hrs, 4-day adult		(83)
Ethanol 2.5% 3 hrs, larvae L3		(238)
Ethanol 5% 3 hrs, larvae L3		(218)
Ethanol 10% 3 hrs, larvae L3		(264)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(142)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(118)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(75)
Paraquat 5 mM 48 hrs, 4-day adult		(232)
Paraquat 10 mM 48 hrs, 4-day adult		(294)
Rotenone 2 μg 12 hrs, larvae L3		(229)
Rotenone 8 μg 12 hrs, larvae L3		(361)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		98
cold shock, 4-day adult		68
heat shock, 4-day adult		(253)
Cadmium 50 mM 6 hrs, larvae L3		(300)
Cadmium 50 mM 12 hrs, larvae L3		70
Cadmium 50 mM 48 hrs, 4-day adult		(192)
Cadmium 100 mM 48 hrs, 4-day adult		(130)
Copper 0.5 mM 12 hrs, larvae L3		(121)
Copper 15 mM 48 hrs, 4-day adult		58
Zinc 5 mM 12 hrs, larvae L3		82
Zinc 4.5 mM 48 hrs, 4-day adult		83
Ethanol 2.5% 3 hrs, larvae L3		(238)
Ethanol 5% 3 hrs, larvae L3		(218)
Ethanol 10% 3 hrs, larvae L3		(264)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(142)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(118)
Caffeine 25 mg/ml 48 hrs, 4-day adult		75
Paraquat 5 mM 48 hrs, 4-day adult		(232)
Paraquat 10 mM 48 hrs, 4-day adult		(294)
Rotenone 2 μg 12 hrs, larvae L3		(229)
Rotenone 8 μg 12 hrs, larvae L3		(361)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		98
cold shock, 4-day adult		68
heat shock, 4-day adult		253
Cadmium 50 mM 6 hrs, larvae L3		300
Cadmium 50 mM 12 hrs, larvae L3		70
Cadmium 50 mM 48 hrs, 4-day adult		192
Cadmium 100 mM 48 hrs, 4-day adult		130
Copper 0.5 mM 12 hrs, larvae L3		121
Copper 15 mM 48 hrs, 4-day adult		58
Zinc 5 mM 12 hrs, larvae L3		82
Zinc 4.5 mM 48 hrs, 4-day adult		83
Ethanol 2.5% 3 hrs, larvae L3		238
Ethanol 5% 3 hrs, larvae L3		218
Ethanol 10% 3 hrs, larvae L3		264
Caffeine 1.5 mg/ml 4 hrs, larvae L3		142
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		118
Caffeine 25 mg/ml 48 hrs, 4-day adult		75
Paraquat 5 mM 48 hrs, 4-day adult		232
Paraquat 10 mM 48 hrs, 4-day adult		294
Rotenone 2 μg 12 hrs, larvae L3		229
Rotenone 8 μg 12 hrs, larvae L3		361
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		98
cold shock, 4-day adult		68
heat shock, 4-day adult		253
Cadmium 50 mM 6 hrs, larvae L3		300
Cadmium 50 mM 12 hrs, larvae L3		70
Cadmium 50 mM 48 hrs, 4-day adult		192
Cadmium 100 mM 48 hrs, 4-day adult		130
Copper 0.5 mM 12 hrs, larvae L3		121
Copper 15 mM 48 hrs, 4-day adult		58
Zinc 5 mM 12 hrs, larvae L3		82
Zinc 4.5 mM 48 hrs, 4-day adult		83
Ethanol 2.5% 3 hrs, larvae L3		238
Ethanol 5% 3 hrs, larvae L3		218
Ethanol 10% 3 hrs, larvae L3		264
Caffeine 1.5 mg/ml 4 hrs, larvae L3		142
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		118
Caffeine 25 mg/ml 48 hrs, 4-day adult		75
Paraquat 5 mM 48 hrs, 4-day adult		232
Paraquat 10 mM 48 hrs, 4-day adult		294
Rotenone 2 μg 12 hrs, larvae L3		229
Rotenone 8 μg 12 hrs, larvae L3		361
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(98)
cold shock, 4-day adult		(68)
heat shock, 4-day adult		(253)
Cadmium 50 mM 6 hrs, larvae L3		(300)
Cadmium 50 mM 12 hrs, larvae L3		(70)
Cadmium 50 mM 48 hrs, 4-day adult		(192)
Cadmium 100 mM 48 hrs, 4-day adult		(130)
Copper 0.5 mM 12 hrs, larvae L3		(121)
Copper 15 mM 48 hrs, 4-day adult		(58)
Zinc 5 mM 12 hrs, larvae L3		(82)
Zinc 4.5 mM 48 hrs, 4-day adult		(83)
Ethanol 2.5% 3 hrs, larvae L3		(238)
Ethanol 5% 3 hrs, larvae L3		(218)
Ethanol 10% 3 hrs, larvae L3		(264)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(142)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(118)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(75)
Paraquat 5 mM 48 hrs, 4-day adult		(232)
Paraquat 10 mM 48 hrs, 4-day adult		(294)
Rotenone 2 μg 12 hrs, larvae L3		(229)
Rotenone 8 μg 12 hrs, larvae L3		(361)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		98
cold shock, 4-day adult		68
heat shock, 4-day adult		(253)
Cadmium 50 mM 6 hrs, larvae L3		(300)
Cadmium 50 mM 12 hrs, larvae L3		70
Cadmium 50 mM 48 hrs, 4-day adult		(192)
Cadmium 100 mM 48 hrs, 4-day adult		130
Copper 0.5 mM 12 hrs, larvae L3		121
Copper 15 mM 48 hrs, 4-day adult		58
Zinc 5 mM 12 hrs, larvae L3		82
Zinc 4.5 mM 48 hrs, 4-day adult		83
Ethanol 2.5% 3 hrs, larvae L3		(238)
Ethanol 5% 3 hrs, larvae L3		(218)
Ethanol 10% 3 hrs, larvae L3		(264)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		142
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		118
Caffeine 25 mg/ml 48 hrs, 4-day adult		75
Paraquat 5 mM 48 hrs, 4-day adult		(232)
Paraquat 10 mM 48 hrs, 4-day adult		(294)
Rotenone 2 μg 12 hrs, larvae L3		(229)
Rotenone 8 μg 12 hrs, larvae L3		(361)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		98
cold shock, 4-day adult		68
heat shock, 4-day adult		253
Cadmium 50 mM 6 hrs, larvae L3		300
Cadmium 50 mM 12 hrs, larvae L3		70
Cadmium 50 mM 48 hrs, 4-day adult		192
Cadmium 100 mM 48 hrs, 4-day adult		130
Copper 0.5 mM 12 hrs, larvae L3		121
Copper 15 mM 48 hrs, 4-day adult		58
Zinc 5 mM 12 hrs, larvae L3		82
Zinc 4.5 mM 48 hrs, 4-day adult		83
Ethanol 2.5% 3 hrs, larvae L3		238
Ethanol 5% 3 hrs, larvae L3		218
Ethanol 10% 3 hrs, larvae L3		264
Caffeine 1.5 mg/ml 4 hrs, larvae L3		142
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		118
Caffeine 25 mg/ml 48 hrs, 4-day adult		75
Paraquat 5 mM 48 hrs, 4-day adult		232
Paraquat 10 mM 48 hrs, 4-day adult		294
Rotenone 2 μg 12 hrs, larvae L3		229
Rotenone 8 μg 12 hrs, larvae L3		361
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

AT02348

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0250814

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG4169

Stages(s) 9-10

Stages(s) 11-12

Stages(s) 13-16

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal

CG4169^GD11238

partially lethal - majority die | pupal stage, with Scer\GAL4^pnr-MD237

CG4169^GD11238

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

CG4169^GD11238

Phenotype manifest in

Allele

embryonic/larval brain | larval stage

CG4169^GD11238

mesothoracic tergum, with Scer\GAL4^pnr-MD237

CG4169^GD11238

trichogen cell, with Scer\GAL4^pnr-MD237

CG4169^GD11238

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG4169	Class	Mutagen	Stocks	Known lesion
CG4169^HP30793			1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG4169	Mutagen	Stocks	Known lesion
CG4169^GD11238	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG4169^KK108812	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG4169^NIG.4169R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes