22C10, mAb22C10, mAb 22C10, MAP1B, EG:49E4.1
microtubule-associated protein regulating axon guidance - Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of Amyotrophic Lateral Sclerosis
Gene model reviewed during 5.53
Several minor light chains can be created with markedly different pIs.
Phosphorylated by SGG/GSK3. Phosphorylated by LRRK2 at the presynapse of neuromuscular junctions, which negatively regulates the activity controlling synaptic differentiation.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\futsch using the Feature Mapper tool.
Expressed in the vast majority of central and peripheral neurons.
Expression assayed at stages 9, 11, 13, and 17. Expression may be continuous between assayed stages in some tissues.
GBrowse - Visual display of RNA-Seq signalsView Dmel\futsch in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Annotations CG3064 and CG14772 merged as CG34387 in release 5.2 of the genome annotation.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
futsch is German for "gone".