Gene model reviewed during 5.49
Gene model reviewed during 5.55
Component of the ribosome quality control complex (RQC), composed of at least the E3 ubiquitin ligase l(3)76BDr/LTN1 and Clbn/NEMF. The complex probably also contains TCF25 as well as TER94/VCP and its ubiquitin-binding cofactors. RQC forms a stable complex with 60S ribosomal subunits (By similarity). Interacts (via its C-terminus) with pros (via its homeobox) (PubMed:16103875). Interacts (via its N-terminus) with emb (PubMed:16103875).
The N-terminal domain contains a nuclear export signal. The C-terminal domain may interact with cargo proteins.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Clbn using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Clbn in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Clbn CG11847