Gene Dmel\Mlp60A

60A-60B

(Stronach et al., 1994)

Experimentally Determined Recombination Data

Location

(Arber, 1994.8.22, Beckerle, 1995.9.9)

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\Mlp60A for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene merge based on protein alignment (BLASTX) data

Gene merge based on EST/cDNA data

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

Mlp60A-RB

FBtr0299697

NM_001144278

2057

486

Mlp60A-RE

FBtr0299696

NM_176255

437

Additional Transcript Data & Comments

Reported size (kB)

0.5 (northern blot)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

Mlp60A-PB

FBpp0288975

53.0

486

8.18

NP_001137750

ACL83203

Mlp60A-PE

FBpp0288974

10.0

8.33

NP_788435

AAF47158

Additional Polypeptide Data & Comments

Reported size (kDa)

92 (aa)

9 (kD)

Comments

External Data

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, LIM-type (IPR001781)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

P53777

UniProtKB/TrEMBL

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 17

somatic mesoderm

visceral mesoderm

embryonic stage 16

embryonic/larval somatic muscle

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

pharyngeal muscle

embryonic stage -- adult stage

embryonic stage 14 -- 17

visceral mesoderm

somatic mesoderm

Additional Descriptive Data

Mlp60A transcripts are first detected by northern blot analysis in 8-12hr embryos, peak in 16-24hr embryos, are present in low levels in larvae, show a second peak of expression in pupae, and persist in adults. They are detected by in situ hybridization starting in embryonic stage 14 in the growing syncytial myotubes. They are present in the completed pattern of somatic muscles in stage 16 embryos where they are distributed throughout the mature myotubes. Transcripts are also expressed in the visceral mesoderm and the pharyngeal muscle.

Mlp60A transcripts are detected from stage 13 in the developing muscles of the somatic and visceral mesoderm, subsequent to the formation of muscle precursor cells.

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage

embryonic/larval visceral muscle

embryonic/larval somatic muscle

pharyngeal muscle

embryonic stage 16

embryonic/larval visceral muscle

(Stronach et al., 1999)

embryonic/larval somatic muscle

(Stronach et al., 1999)

pharyngeal muscle

(Stronach et al., 1999)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Mlp60A protein is detected beginning in stage 14 embryos in somatic, visceral and pharyngeal muscles. Protein is found throughout the myotube. Mlp60A protein appears to associate with linear cytoplasmic elements in the muscle cell syncytium that are thought to be the sarcomeric actin filament network.

(The modENCODE Consortium, 2010)

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0259209

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	max expr for FBgn0259209
	Very low expression bin max
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
[download data (TSV)]

Guide to modENCODE expression level colors
	No expression (0 - 0)
	Extremely low expression (1 - 10)
	Very low expression (11 - 100)
	Low expression (101 - 400)
	Moderate expression (401 - 1400)
	Moderately high expression (1401 - 4000)
	High expression (4001 - 10000)
	Very high expression (10001 - 100000)
	Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0259209 expression level
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		3543
embryo 14-16hr		19786
embryo 16-18hr		37481
embryo 18-20hr		46357
embryo 20-22hr		38718
embryo 22-24hr		31288
larva L1		31004
larva L2		20781
larva L3 12hr old		24948
larva L3 puffstage 1-2		16879
larva L3 puffstage 3-6		5551
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		17191
pupae 3d postWPP		44810
pupae 4d postWPP		33496
adult male 01day		15575
adult male 05day		8369
adult male 30day		6121
adult female 01day		14563
adult female 05day		2421
adult female 30day		2506
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

Linear, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(146)
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		(192)
embryo 08-10hr		(497)
embryo 10-12hr		(1872)
embryo 12-14hr		(3543)
embryo 14-16hr		(19786)
embryo 16-18hr		(37481)
embryo 18-20hr		(46357)
embryo 20-22hr		(38718)
embryo 22-24hr		(31288)
larva L1		(31004)
larva L2		(20781)
larva L3 12hr old		(24948)
larva L3 puffstage 1-2		(16879)
larva L3 puffstage 3-6		(5551)
larva L3 puffstage 7-9		(2402)
white prepupae new		(707)
white prepupae 12hr		(1426)
white prepupae 24hr		(1415)
pupae 2d postWPP		(17191)
pupae 3d postWPP		(44810)
pupae 4d postWPP		(33496)
adult male 01day		(15575)
adult male 05day		(8369)
adult male 30day		(6121)
adult female 01day		(14563)
adult female 05day		(2421)
adult female 30day		(2506)
Expression Level Scale		None Extremely low Very low Low

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		(1872)
embryo 12-14hr		(3543)
embryo 14-16hr		(19786)
embryo 16-18hr		(37481)
embryo 18-20hr		(46357)
embryo 20-22hr		(38718)
embryo 22-24hr		(31288)
larva L1		(31004)
larva L2		(20781)
larva L3 12hr old		(24948)
larva L3 puffstage 1-2		(16879)
larva L3 puffstage 3-6		(5551)
larva L3 puffstage 7-9		(2402)
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		(17191)
pupae 3d postWPP		(44810)
pupae 4d postWPP		(33496)
adult male 01day		(15575)
adult male 05day		(8369)
adult male 30day		(6121)
adult female 01day		(14563)
adult female 05day		(2421)
adult female 30day		(2506)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		3543
embryo 14-16hr		(19786)
embryo 16-18hr		(37481)
embryo 18-20hr		(46357)
embryo 20-22hr		(38718)
embryo 22-24hr		(31288)
larva L1		(31004)
larva L2		(20781)
larva L3 12hr old		(24948)
larva L3 puffstage 1-2		(16879)
larva L3 puffstage 3-6		5551
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		(17191)
pupae 3d postWPP		(44810)
pupae 4d postWPP		(33496)
adult male 01day		(15575)
adult male 05day		8369
adult male 30day		6121
adult female 01day		(14563)
adult female 05day		2421
adult female 30day		2506
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		3543
embryo 14-16hr		19786
embryo 16-18hr		37481
embryo 18-20hr		46357
embryo 20-22hr		38718
embryo 22-24hr		31288
larva L1		31004
larva L2		20781
larva L3 12hr old		24948
larva L3 puffstage 1-2		16879
larva L3 puffstage 3-6		5551
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		17191
pupae 3d postWPP		44810
pupae 4d postWPP		33496
adult male 01day		15575
adult male 05day		8369
adult male 30day		6121
adult female 01day		14563
adult female 05day		2421
adult female 30day		2506
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to maximum FBgn0259209 expression level
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		3543
embryo 14-16hr		19786
embryo 16-18hr		37481
embryo 18-20hr		46357
embryo 20-22hr		38718
embryo 22-24hr		31288
larva L1		31004
larva L2		20781
larva L3 12hr old		24948
larva L3 puffstage 1-2		16879
larva L3 puffstage 3-6		5551
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		17191
pupae 3d postWPP		44810
pupae 4d postWPP		33496
adult male 01day		15575
adult male 05day		8369
adult male 30day		6121
adult female 01day		14563
adult female 05day		2421
adult female 30day		2506
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		(146)
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		(192)
embryo 08-10hr		(497)
embryo 10-12hr		(1872)
embryo 12-14hr		(3543)
embryo 14-16hr		(19786)
embryo 16-18hr		(37481)
embryo 18-20hr		(46357)
embryo 20-22hr		(38718)
embryo 22-24hr		(31288)
larva L1		(31004)
larva L2		(20781)
larva L3 12hr old		(24948)
larva L3 puffstage 1-2		(16879)
larva L3 puffstage 3-6		(5551)
larva L3 puffstage 7-9		(2402)
white prepupae new		(707)
white prepupae 12hr		(1426)
white prepupae 24hr		(1415)
pupae 2d postWPP		(17191)
pupae 3d postWPP		(44810)
pupae 4d postWPP		(33496)
adult male 01day		(15575)
adult male 05day		(8369)
adult male 30day		(6121)
adult female 01day		(14563)
adult female 05day		(2421)
adult female 30day		(2506)
Expression Level Scale		None Extremely low Very low Low

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		(3543)
embryo 14-16hr		(19786)
embryo 16-18hr		(37481)
embryo 18-20hr		(46357)
embryo 20-22hr		(38718)
embryo 22-24hr		(31288)
larva L1		(31004)
larva L2		(20781)
larva L3 12hr old		(24948)
larva L3 puffstage 1-2		(16879)
larva L3 puffstage 3-6		(5551)
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		(17191)
pupae 3d postWPP		(44810)
pupae 4d postWPP		(33496)
adult male 01day		(15575)
adult male 05day		(8369)
adult male 30day		(6121)
adult female 01day		(14563)
adult female 05day		2421
adult female 30day		(2506)
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		3543
embryo 14-16hr		19786
embryo 16-18hr		(37481)
embryo 18-20hr		(46357)
embryo 20-22hr		(38718)
embryo 22-24hr		(31288)
larva L1		(31004)
larva L2		(20781)
larva L3 12hr old		(24948)
larva L3 puffstage 1-2		16879
larva L3 puffstage 3-6		5551
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		17191
pupae 3d postWPP		(44810)
pupae 4d postWPP		(33496)
adult male 01day		15575
adult male 05day		8369
adult male 30day		6121
adult female 01day		14563
adult female 05day		2421
adult female 30day		2506
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		146
embryo 02-04hr		53
embryo 04-06hr		61
embryo 06-08hr		192
embryo 08-10hr		497
embryo 10-12hr		1872
embryo 12-14hr		3543
embryo 14-16hr		19786
embryo 16-18hr		37481
embryo 18-20hr		46357
embryo 20-22hr		38718
embryo 22-24hr		31288
larva L1		31004
larva L2		20781
larva L3 12hr old		24948
larva L3 puffstage 1-2		16879
larva L3 puffstage 3-6		5551
larva L3 puffstage 7-9		2402
white prepupae new		707
white prepupae 12hr		1426
white prepupae 24hr		1415
pupae 2d postWPP		17191
pupae 3d postWPP		44810
pupae 4d postWPP		33496
adult male 01day		15575
adult male 05day		8369
adult male 30day		6121
adult female 01day		14563
adult female 05day		2421
adult female 30day		2506
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

FlyAtlas Anatomical Expression Data for FBgn0259209

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	max expr for FBgn0259209
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult crop, larval/adult midgut, larval/adult hindgut, adult heart, larval trachea, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval Malpighian tubules, adult fat body, adult female reproductive system, adult testis.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (1000 - 25000)

Heatmap
Tissue		Expression Level
Larval Central Nervous System		no informative data
Larval Midgut		no informative data
Larval Hindgut		no informative data
Larval Malpighian Tubules		no informative data
Larval Fat Body
Larval Salivary Gland		no informative data
Larval Trachea		no informative data
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		no informative data
Adult Brain		no informative data
Adult Thoracic-Abdominal Ganglion		no informative data
Adult Crop		no informative data
Adult Midgut		no informative data
Adult Hindgut		no informative data
Adult Malpighian Tubules		no informative data
Adult Fat Body		no informative data
Adult Salivary Gland
Adult Heart		no informative data
Adult VirginFemale Spermatheca		no informative data
Adult InseminatedFemale Spermatheca		no informative data
Adult Ovary		no informative data
Adult Testis		no informative data
Adult Male Accessory Gland		no informative data
Adult Carcass		no informative data

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

mE2_34_mRNA_expression_cluster_18

External Data & Images

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0259209

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG30179-RA;CG30174-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

Phenotype manifest in

Allele

Classical Alleles ( 2 )

For All Classical Alleles Show

Allele of Mlp60A	Class	Mutagen	Stocks	Known lesion
Mlp60A^G5733		P-element activity	1	--
Mlp60A^G7762		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Mlp60A	Mutagen	Stocks	Known lesion
Mlp60A^GD13576	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
Mlp60A^GD15072	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
Mlp60A^GD12919	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Mlp60A^JF03313	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Mlp60A^KK110175	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Mlp60A^KK110600	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Mlp60A^KK112356	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes

Aneuploid Aberrations

Disrupted in

Df(2R)Exel6081

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EP}Mlp60A^G5733

P{EP}Mlp60A^G7762

Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )

Terms Based on Experimental Evidence ( 3 terms )

Molecular Function ( 0 terms)

Biological Process

CV term

muscle tissue development

References

inferred from expression pattern

Cellular Component

CV term

References

colocalizes_with
actin cytoskeleton

inferred from direct assay

nucleus

inferred from direct assay

(Arber and Caroni, 1996)

Terms Based on Predictions or Assertions ( 4 terms )

Molecular Function

CV term

(FlyBase Curators et al., 2004-)

References

zinc ion binding

inferred from electronic annotation with InterPro:IPR001781

non-traceable author statement

Biological Process

CV term

regulation of striated muscle tissue development

References

non-traceable author statement

Cellular Component

CV term

References

cytoplasm

non-traceable author statement

nucleus

non-traceable author statement

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

Mlp60A allele

Gene

References

External Data

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0259209

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

37853

Orthologs

Genome-wide drosophilid orthologs

Dana\GF11369

Dere\GG22934

Dere\GG22935

Dere\GG22937

Dgri\GH21720

Dmoj\GI20682

Dper\GL11662

Dper\GL11663

Dpse\GA24805

Dsec\GM18301

Dsim\GD11833

Dsim\GD11834

Dsim\GD15459

Dvir\GJ20431

Dwil\GK21388

Dyak\GE14374

Dyak\GE14375

Dyak\Mlp60A

Curated drosophilid orthologs

Dpse\GA15703

Dpse\GA17323

Dyak\Mlp60A

y¹ v¹; P{TRiP.JF03313}attP2

InParanoid A subset of ortholog calls from InParanoid.

•

15575
Batrachochytrium dendrobatidis (chytrid fungus)
80283
Phytophthora ramorum (sudden oak death pathogen)

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

•

Stocks & Reagents

Stocks Listed in FlyBase ( 11 )

Bloomington

29381

27185

y¹ w^*; P{EP}Mlp60A^G5733

27970

y¹ w^*; P{EP}Mlp60A^G7762

v101898

v102399

v102757

v23511

w¹¹¹⁸; P{GD13576}v23511

v23512

w¹¹¹⁸; P{GD13576}v23512

v26836

w¹¹¹⁸; P{GD12919}v26836

v45060

w¹¹¹⁸; P{GD15072}v45060

v45058

w¹¹¹⁸; P{GD15072}v45058/TM3

Genomic Clones ( 1 )

BACR27M17

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 74 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

DRSC - Results from RNAi screens.

•

FBgn0259209

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

Antibody Information

polyclonal

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for identity of: Mlp60A CG3220

(Wang, 1999.11)

Source for database merge of

Source for merge of: Mlp60A BcDNA:RE14544

(FlyBase, 1996-)

Source for merge of: Mlp60A BcDNA:RH74176

(FlyBase, 1996-)

Source for merge of: Mlp60A CG30174 CG30179

Additional comments

Annotations CG33149, CG30174 and CG30179 merged as CG42309 in release 5.9 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003, FlyBase, 1996-)

Source for merge of Mlp60A BcDNA:RH74176 was a shared cDNA (date:030728).

Source for merge of Mlp60A BcDNA:RE14544 was a shared cDNA (date:030728).

(FlyBase, 1996-)

Other Comments

Protein has a single LIM domain and is expressed in the muscle.

(Stronach, 1996.2.12)

Mlp60A protein is identified and developmental expression pattern determined. Results reveal a striking conservation of sequence, timing of gene expression, tissue distribution of gene products and subcellular localisation among LIM proteins of vertebrates and invertebrates.

During embryogenesis Mlp60A expression is associated with developing muscles of the visceral and somatic mesoderm subsequent to the formation of muscle precursor cells.

(Keleman et al., 2009.8.5)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

37853

UniProtKB/Swiss-Prot

•

P53777

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, LIM-type (IPR001781)

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0259209

DRSC - Results from RNAi screens.

•

FBgn0259209

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0259209

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG30179-RA;CG30174-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0259209

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

InParanoid A subset of ortholog calls from InParanoid.

•

15575
Batrachochytrium dendrobatidis (chytrid fungus)
80283
Phytophthora ramorum (sudden oak death pathogen)

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

•

/cytoskel/muslimp1.htm

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

37853

modMine - Data generated by the modENCODE project.

•

FBgn0259209

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

•

Synonyms & Secondary IDs ( 19 )

Reported As

Symbol Synonym

BcDNA:RE14544

BcDNA:RH74176

CG3220

(Whitfield, 2001.2.19, Whitfield, 2000.12.19, )

CG30174

CG30179

(Keleman et al., 2009.8.5)

CG33149

(Keleman et al., 2009.8.5, Perkins et al., 2009, Cammarato et al., 2011)

CG42309

(Weiskirchen and Gunther, 2003, Arber et al., 1994)

DLim-2

DmLIM-2

(Stronach et al., 1996, Stronach et al., 1995, Stronach et al., 1994, )

DMlp1

DMLP1

(Lin et al., 1997, Arber and Caroni, 1996)

dMlp60A

(Weiskirchen and Gunther, 2003)

MLP

MLP1

(Arber, 1994.8.22)

Mlp1

Mlp60A

(Clark et al., 2007, Montana and Littleton, 2006, Sandmann et al., 2006, Junion et al., 2007, Bulchand et al., 2010)

Name Synonym

CG30174

CG30179

CG42309

(Sandmann et al., 2006, Cammarato et al., 2011)

Muscle LIM protein 60A

(Bulchand et al., 2010)

Muscle LIM protein at 60A

Muscle-specific LIM protein at 60A