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Gene Dmel\PMCA

General Information
Symbol	Dmel\PMCA	Species	D. melanogaster
Name	plasma membrane calcium ATPase	Annotation symbol	CG42314
Feature type	protein_coding_gene	FlyBase ID	FBgn0259214
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	CG2165, BEST:CK01140
Genomic Location
Chromosome (arm)	4	Recombination map
Cytogenetic map	102B5-102B5	Sequence location	4:349,442..379,526 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene plasma membrane calcium ATPase is referred to in FlyBase by the symbol Dmel\PMCA (CG42314, FBgn0259214). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: calcium-transporting ATPase activity. There is experimental evidence that it is involved in the biological process: cellular calcium ion homeostasis. 11 alleles are reported. No phenotypic data is available. It has 11 annotated transcripts and 11 annotated polypeptides. Protein features are: ATPase, P-type, cytoplasmic transduction domain A; ATPase, P-type cation-transporter, C-terminal; ATPase, P-type cation-transporter, N-terminal; ATPase, P-type phosphorylation site; ATPase, P-type, transmembrane domain; ATPase, P-type, ATPase-associated domain; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; ATPase, P-type, calcium-transporting, PMCA-type; ATPase, P-type, cytoplasmic domain N; HAD-like domain; Plasma membrane calcium transporter ATPase C-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 18-24 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult midgut, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland. Gene sequence location is 4:349442..379526.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood References Knowles-Barley, 2011.8.24, BrainTrap expression curation.
FB2012_01	References Rui et al., 2010, PLoS Genet. 6(11): e1001208 Sequence features HFA17114 HFA17154 BKN42380 HFA17113 BKN28105
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 102B5-102B5   Limits computationally determined from genome sequence between P{SUPor-P}CrkKG00336&P{SUPor-P}KG00711 and P{SUPor-P}KG02769
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\PMCA for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	No completely sequenced cDNA identifed. Assignment of alternative 5' and 3' ends to a particular transcript is hypothetical.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) PMCA-RI FBtr0300554  NM_166754   4134   1206 PMCA-RJ FBtr0300555  NM_001038714   4739   1255 PMCA-RK FBtr0300556  NM_001014688   4065   1183 PMCA-RL FBtr0300557  NM_166755   4068   1206 PMCA-RM FBtr0300558  NM_001014689   4599   1255 PMCA-RN FBtr0300559  NM_001014687   3856   1120 PMCA-RO FBtr0304046  NM_001201585   4084   1206 PMCA-RP FBtr0304047  NM_001201586   4032   1194 PMCA-RQ FBtr0304048  NM_001201587   4077   1187 PMCA-RR FBtr0304049  NM_001201588   4067   1210 PMCA-RS FBtr0304050  NM_001201589   5938   1255
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein PMCA-PI   FBpp0289781   132.9   1206   6.55     NP_726564   AAF59350 PMCA-PJ   FBpp0289782   138.7   1255   7.58     NP_001033803   ABC65829 PMCA-PK   FBpp0289783   130.4   1183   6.62     NP_001014688   AAX52514 PMCA-PL   FBpp0289784   132.9   1206   6.55     NP_726565   AAN06528 PMCA-PM   FBpp0289785   138.7   1255   7.58     NP_001014689   AAX52515 PMCA-PN   FBpp0289786   123.4   1120   6.68     NP_001014687   AAX52516 PMCA-PO   FBpp0293009   132.9   1206   6.55     NP_001188514   ADV37598 PMCA-PP   FBpp0293010   131.6   1194   6.35     NP_001188515   ADV37599 PMCA-PQ   FBpp0293011   130.8   1187   6.62     NP_001188516   ADV37600 PMCA-PR   FBpp0293012   133.3   1210   6.55     NP_001188517   ADV37601 PMCA-PS   FBpp0293013   138.7   1255   7.58     NP_001188518   ADV37602
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ATPase, P-type phosphorylation site (IPR018303) ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (IPR001757) ATPase, P-type cation-transporter, N-terminal (IPR004014) ATPase, P-type cation-transporter, C-terminal (IPR006068) ATPase, P-type, calcium-transporting, PMCA-type (IPR006408) ATPase, P-type, ATPase-associated domain (IPR008250) Plasma membrane calcium transporter ATPase C-terminal (IPR022141) HAD-like domain (IPR023214) ATPase, P-type, transmembrane domain (IPR023298) ATPase, P-type, cytoplasmic domain N (IPR023299) ATPase, P-type, cytoplasmic transduction domain A (IPR023300)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141084   AA141532   AA141681   AA141682   AA202486   AA440740   AA567525   AA697438   AA735469   AE014135 AAF59350   AE014135 AAN06528   AE014135 AAX52514   AE014135 AAX52515   AE014135 AAX52516   AE014135 ABC65829   AE014135 ADV37598   AE014135 ADV37599   AE014135 ADV37600   AE014135 ADV37601   AE014135 ADV37602   AI064194   AI064240   AI259435   AI292539   AI455135   AW941487   AY060934   BI213371   BI363153   BI363310   BI365659   BI481611   BI483915   BI569688   BI569868   BI570115   BI608195   BI620300   BI639053   BP545409   BP545410   BP547896   BP548324   BP556382   BP556383   BP556439   BP556440   BP556535   BP556536   BP559946   BP559947   BT011201   BT024963   CA804714   CO152726   CO176798   CO177925   CO178581   CO183669   CO185929   CO187464   CO187611   CO187930   CO189606   CO190487   CO192855   CO194824   CO195741   CO195914   CO196543   CO196547   CO262125   CO262423   CO262424   CO262525   CO262557   CO263181   CO263757   CO264208   CO265201   CO266886   CO267183   CO268136   CO268165   CO268465   CO268472   CO269608   CO269722   CO270985   CO271873   CO273302   CO274198   CO274227   CO275653   CO277196   CO278560   CO279087   CO279920   CO280716   CO281160   CO282871   CO284338   CO284898   CO285041   CO287857   CO288110   CO288520   CO289064   CO289136   CO290130   CO291154   CO291226   CO291339   CO291368   CO292282   CO292340   CO295204   CO296919   CO297984   CO298133   CO299152   CO299270   CO299682   CO300829   CO301535   CO302618   CO303074   CO304393   CO304650   CO304745   CO304756   CO305433   CO305460   CO306929   CO306944   CO308608   CO308613   CO309434   CO310963   CO311532   CO313505   CO313550   CO313555   CO313737   CO314920   CO319713   CO319796   CO320002   CO322024   CO322547   CO322834   CO322904   CO323955   CO325000   CO325240   CO326439   CO327068   CO328442   CO330264   CO330455   CO331688   CO332178   CO334110   CO341418   CO342162   CO342411   CO343294   CO343965   CO344003   CO344190   CO344256   CO345051   CO345063   CO345110   CO345173   CX309645   CX309646   CZ469074   CZ471184   CZ478772   EC057299   EC057535   EC059119   EC059276   EC059845   EC061207   EC062411   EC063414   EC064518   EC065203   EC065264   EC065272   EC065578   EC065973   EC066023   EC066160   EC066285   EC066524   EC067595   EC068226   EC068227   EC068318   EC069035   EC069132   EC069467   EC069745   EC070113   EC070737   EC076949   EC077707   EC078167   EC078956   EC079234   EC081163   EC082151   EC084410   EC085685   EC086732   EC089672   EC089844   EC194712   EC196114   EC196528   EC196568   EC196844   EC196936   EC198284   EC200114   EC200378   EC200847   EC201814   EC201924   EC203507   EC204548   EC204589   EC204926   EC207675   EC207984   EC208182   EC208209   EC208456   EC208457   EC210492   EC210736   EC212729   EC216824   EC217137   EC217223   EC219134   EC219302   EC220005   EC220494   EC221465   EC222573   EC222841   EC225173   EC226085   EC226112   EC226135   EC226257   EC227273   EC228000   EC229183   EC229474   EC230863   EC230928   EC231762   EC233338   EC234807   EC235036   EC235212   EC236164   EC237222   EC237715   EC239525   EC239674   EC241026   EC241978   EC242464   EC243248   EC243821   EC245249   EC245772   EC246108   EC246422   EC249099   EC249218   EC250279   EC252782   EC253693   EC253843   EC253934   EC254793   EC254854   EC255189   EC256074   EC257303   EC257446   EC257547   EC257558   EC257699   EC258635   EC260100   EC260784   EL883988   EL883989   EL884232   EL884233   ES694182
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	E6EK17 E6EK18 E6EK15 Q9V4C7 Q59DQ0 Q59DP8 Q59DP9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0259214    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0259214 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 18-24 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0259214 expression level Developmental Stage   Expression Level embryo 00-02hr    2654 embryo 02-04hr    4200 embryo 04-06hr    5134 embryo 06-08hr    3165 embryo 08-10hr    4441 embryo 10-12hr    3996 embryo 12-14hr    8171 embryo 14-16hr    3717 embryo 16-18hr    7068 embryo 18-20hr    5703 embryo 20-22hr    7002 embryo 22-24hr    10662 larva L1    5030 larva L2    5298 larva L3 12hr old    4724 larva L3 puffstage 1-2    2619 larva L3 puffstage 3-6    3315 larva L3 puffstage 7-9    4534 white prepupae new    4674 white prepupae 12hr    4087 white prepupae 24hr    4309 pupae 2d postWPP    5752 pupae 3d postWPP    9502 pupae 4d postWPP    3948 adult male 01day    5098 adult male 05day    3024 adult male 30day    2139 adult female 01day    2646 adult female 05day    3357 adult female 30day    2574 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2654) embryo 02-04hr  (4200) embryo 04-06hr  (5134) embryo 06-08hr  (3165) embryo 08-10hr  (4441) embryo 10-12hr  (3996) embryo 12-14hr  (8171) embryo 14-16hr  (3717) embryo 16-18hr  (7068) embryo 18-20hr  (5703) embryo 20-22hr  (7002) embryo 22-24hr  (10662) larva L1  (5030) larva L2  (5298) larva L3 12hr old  (4724) larva L3 puffstage 1-2  (2619) larva L3 puffstage 3-6  (3315) larva L3 puffstage 7-9  (4534) white prepupae new  (4674) white prepupae 12hr  (4087) white prepupae 24hr  (4309) pupae 2d postWPP  (5752) pupae 3d postWPP  (9502) pupae 4d postWPP  (3948) adult male 01day  (5098) adult male 05day  (3024) adult male 30day  (2139) adult female 01day  (2646) adult female 05day  (3357) adult female 30day  (2574) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2654) embryo 02-04hr  (4200) embryo 04-06hr  (5134) embryo 06-08hr  (3165) embryo 08-10hr  (4441) embryo 10-12hr  (3996) embryo 12-14hr  (8171) embryo 14-16hr  (3717) embryo 16-18hr  (7068) embryo 18-20hr  (5703) embryo 20-22hr  (7002) embryo 22-24hr  (10662) larva L1  (5030) larva L2  (5298) larva L3 12hr old  (4724) larva L3 puffstage 1-2  (2619) larva L3 puffstage 3-6  (3315) larva L3 puffstage 7-9  (4534) white prepupae new  (4674) white prepupae 12hr  (4087) white prepupae 24hr  (4309) pupae 2d postWPP  (5752) pupae 3d postWPP  (9502) pupae 4d postWPP  (3948) adult male 01day  (5098) adult male 05day  (3024) adult male 30day  (2139) adult female 01day  (2646) adult female 05day  (3357) adult female 30day  (2574) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2654 embryo 02-04hr    4200 embryo 04-06hr    5134 embryo 06-08hr    3165 embryo 08-10hr    4441 embryo 10-12hr    3996 embryo 12-14hr    8171 embryo 14-16hr    3717 embryo 16-18hr    7068 embryo 18-20hr    5703 embryo 20-22hr    7002 embryo 22-24hr  10662 larva L1    5030 larva L2    5298 larva L3 12hr old    4724 larva L3 puffstage 1-2    2619 larva L3 puffstage 3-6    3315 larva L3 puffstage 7-9    4534 white prepupae new    4674 white prepupae 12hr    4087 white prepupae 24hr    4309 pupae 2d postWPP    5752 pupae 3d postWPP    9502 pupae 4d postWPP    3948 adult male 01day    5098 adult male 05day    3024 adult male 30day    2139 adult female 01day    2646 adult female 05day    3357 adult female 30day    2574 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2654 embryo 02-04hr    4200 embryo 04-06hr    5134 embryo 06-08hr    3165 embryo 08-10hr    4441 embryo 10-12hr    3996 embryo 12-14hr    8171 embryo 14-16hr    3717 embryo 16-18hr    7068 embryo 18-20hr    5703 embryo 20-22hr    7002 embryo 22-24hr    10662 larva L1    5030 larva L2    5298 larva L3 12hr old    4724 larva L3 puffstage 1-2    2619 larva L3 puffstage 3-6    3315 larva L3 puffstage 7-9    4534 white prepupae new    4674 white prepupae 12hr    4087 white prepupae 24hr    4309 pupae 2d postWPP    5752 pupae 3d postWPP    9502 pupae 4d postWPP    3948 adult male 01day    5098 adult male 05day    3024 adult male 30day    2139 adult female 01day    2646 adult female 05day    3357 adult female 30day    2574 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0259214 expression level Developmental Stage   Expression Level embryo 00-02hr    2654 embryo 02-04hr    4200 embryo 04-06hr    5134 embryo 06-08hr    3165 embryo 08-10hr    4441 embryo 10-12hr    3996 embryo 12-14hr    8171 embryo 14-16hr    3717 embryo 16-18hr    7068 embryo 18-20hr    5703 embryo 20-22hr    7002 embryo 22-24hr    10662 larva L1    5030 larva L2    5298 larva L3 12hr old    4724 larva L3 puffstage 1-2    2619 larva L3 puffstage 3-6    3315 larva L3 puffstage 7-9    4534 white prepupae new    4674 white prepupae 12hr    4087 white prepupae 24hr    4309 pupae 2d postWPP    5752 pupae 3d postWPP    9502 pupae 4d postWPP    3948 adult male 01day    5098 adult male 05day    3024 adult male 30day    2139 adult female 01day    2646 adult female 05day    3357 adult female 30day    2574 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2654) embryo 02-04hr  (4200) embryo 04-06hr  (5134) embryo 06-08hr  (3165) embryo 08-10hr  (4441) embryo 10-12hr  (3996) embryo 12-14hr  (8171) embryo 14-16hr  (3717) embryo 16-18hr  (7068) embryo 18-20hr  (5703) embryo 20-22hr  (7002) embryo 22-24hr  (10662) larva L1  (5030) larva L2  (5298) larva L3 12hr old  (4724) larva L3 puffstage 1-2  (2619) larva L3 puffstage 3-6  (3315) larva L3 puffstage 7-9  (4534) white prepupae new  (4674) white prepupae 12hr  (4087) white prepupae 24hr  (4309) pupae 2d postWPP  (5752) pupae 3d postWPP  (9502) pupae 4d postWPP  (3948) adult male 01day  (5098) adult male 05day  (3024) adult male 30day  (2139) adult female 01day  (2646) adult female 05day  (3357) adult female 30day  (2574) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2654) embryo 02-04hr  (4200) embryo 04-06hr  (5134) embryo 06-08hr  (3165) embryo 08-10hr  (4441) embryo 10-12hr  (3996) embryo 12-14hr  (8171) embryo 14-16hr  (3717) embryo 16-18hr  (7068) embryo 18-20hr  (5703) embryo 20-22hr  (7002) embryo 22-24hr  (10662) larva L1  (5030) larva L2  (5298) larva L3 12hr old  (4724) larva L3 puffstage 1-2  (2619) larva L3 puffstage 3-6  (3315) larva L3 puffstage 7-9  (4534) white prepupae new  (4674) white prepupae 12hr  (4087) white prepupae 24hr  (4309) pupae 2d postWPP  (5752) pupae 3d postWPP  (9502) pupae 4d postWPP  (3948) adult male 01day  (5098) adult male 05day  (3024) adult male 30day  2139 adult female 01day  (2646) adult female 05day  (3357) adult female 30day  (2574) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2654 embryo 02-04hr    4200 embryo 04-06hr    5134 embryo 06-08hr    3165 embryo 08-10hr    4441 embryo 10-12hr    3996 embryo 12-14hr    8171 embryo 14-16hr    3717 embryo 16-18hr    7068 embryo 18-20hr    5703 embryo 20-22hr    7002 embryo 22-24hr  10662 larva L1    5030 larva L2    5298 larva L3 12hr old    4724 larva L3 puffstage 1-2    2619 larva L3 puffstage 3-6    3315 larva L3 puffstage 7-9    4534 white prepupae new    4674 white prepupae 12hr    4087 white prepupae 24hr    4309 pupae 2d postWPP    5752 pupae 3d postWPP    9502 pupae 4d postWPP    3948 adult male 01day    5098 adult male 05day    3024 adult male 30day    2139 adult female 01day    2646 adult female 05day    3357 adult female 30day    2574 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2654 embryo 02-04hr    4200 embryo 04-06hr    5134 embryo 06-08hr    3165 embryo 08-10hr    4441 embryo 10-12hr    3996 embryo 12-14hr    8171 embryo 14-16hr    3717 embryo 16-18hr    7068 embryo 18-20hr    5703 embryo 20-22hr    7002 embryo 22-24hr    10662 larva L1    5030 larva L2    5298 larva L3 12hr old    4724 larva L3 puffstage 1-2    2619 larva L3 puffstage 3-6    3315 larva L3 puffstage 7-9    4534 white prepupae new    4674 white prepupae 12hr    4087 white prepupae 24hr    4309 pupae 2d postWPP    5752 pupae 3d postWPP    9502 pupae 4d postWPP    3948 adult male 01day    5098 adult male 05day    3024 adult male 30day    2139 adult female 01day    2646 adult female 05day    3357 adult female 30day    2574 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0259214    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0259214 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult head, larval/adult central nervous system, adult crop, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, larval/adult midgut, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Heatmap Tissue   Expression Level Larval Central Nervous System no informative data Larval Midgut no informative data Larval Hindgut no informative data Larval Malpighian Tubules no informative data Larval Fat Body no informative data Larval Salivary Gland no informative data Larval Trachea no informative data Larval Carcass no informative data Adult Head no informative data Adult Eye no informative data Adult Brain no informative data Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut no informative data Adult Hindgut no informative data Adult Malpighian Tubules no informative data Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca no informative data Adult InseminatedFemale Spermatheca no informative data Adult Ovary no informative data Adult Testis no informative data Adult Male Accessory Gland no informative data Adult Carcass no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0259214 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • HDC16691;CG2165-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal PMCA6-M528 viable, with Scer\GAL4pnr-MD237 PMCAGD3152 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of PMCA Class Mutagen Stocks Known lesion PMCAc04208 piggyBac transposase 1 -- PMCAe00941 piggyBac transposase 1 -- PMCAMB01085 1 -- PMCA6-M528 0 -- PMCAc07034 piggyBac transposase 0 -- PMCACPTI001995 piggyBac transposase 0 Yes
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of PMCA Class Mutagen Stocks Known lesion PMCAGD3152 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PMCAJF01145 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PMCAKK108105 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PMCAdsRNA.cRa in vitro construct - RNAi 0 Yes PMCAKK116060 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(4)5-M244 (Sun et al., 2004) Df(4)5-M275 (Sun et al., 2004)
Partially duplicated in	Dp(4;4)2-M823 (Sun et al., 2004) Dp(4;4)4-M979 (Sun et al., 2004) Dp(4;4)4-M993 (Sun et al., 2004) Dp(4;4)6-M365 (Sun et al., 2004) Dp(4;4)6-M421 (Sun et al., 2004)
Duplicated in	Dp(4;4)5-M345 (Sun et al., 2004) Dp(4;4)6-M180 (Sun et al., 2004) Dp(4;4)6-M350 (Sun et al., 2004) Dp(4;4)6-M397 (Sun et al., 2004)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK116060} NA P{TRiP.JF01145} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{hsp26-pt-T}PMCA6-M528 NA PBac{681.P.FSVS-1}PMCACPTI001995 NA PBac{PB}PMCAc04208 NA PBac{PB}PMCAc07034 NA PBac{RB}PMCAe00941 NA insertion of enhancer trap binary system Mi{ET1}PMCAMB01085 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cellular calcium ion homeostasis inferred from mutant phenotype (Roos et al., 2005)
Cellular Component
CV term Evidence References
plasma membrane inferred from direct assay (Khanna et al., 2010)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR001757, InterPro:IPR006408, InterPro:IPR018303 (FlyBase Curators et al., 2004-) calcium-transporting ATPase activity inferred from sequence or structural similarity with UniProtKB:P11505 (FlyBase, 1992-) metal ion binding inferred from electronic annotation with InterPro:IPR008250 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
ATP biosynthetic process inferred from electronic annotation with InterPro:IPR006408 (FlyBase Curators et al., 2004-) calcium ion transmembrane transport inferred from electronic annotation with InterPro:IPR006408 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
plasma membrane inferred from sequence or structural similarity with UniProtKB:P11505 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions PMCA allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68621 DroID - A comprehensive database of gene and protein interactions. • FBgn0259214 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43787
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21692 Dere\GG16451 Dgri\GH23619 Dmoj\GI14056 Dper\GL18149 Dpse\GA22511 Dsec\GM26783 Dsim\GD24384 Dvir\GJ18346 Dwil\GK13713 Dyak\GE14517
Curated drosophilid orthologs	Dpse\GA15279
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL005561-PA Aedes aegypti (mosquito) AGAP010638-PA Anopheles gambiae (mosquito) XP_001945158.1 Acyrthosiphon pisum (pea aphid) At2g41560.1 Arabidopsis thaliana (wall cress) 35482 Batrachochytrium dendrobatidis (chytrid fungus) 110163 Branchiostoma floridae (lancelet) XP_001902371.1 Brugia malayi (roundworm nematode) BGIBMGA004534-PA Bombyx mori (silk worm) ENSBTAP00000000677 Bos taurus (bovine) CAL0000810 Candida albicans (a form of yeast) CN29319 Caenorhabditis brenneri (small nematode) CBP00914 Caenorhabditis briggsae (nematode) CE28373 Caenorhabditis elegans (worm) ENSCAFP00000007604 Canis familiaris (dog) CAGL0A00517g Candida glabrata (haploid yeast) ENSCINP00000006789 Ciona intestinalis (sea squirt) JA00949 Caenorhabditis japonica (nematode) CMQ379C Cyanidioschyzon merolae (red alga) cn04287 Cryptococcus neoformans (yeast-like fungus) CPIJ005742 Culex pipens (mosquito) ENSCPOP00000014003 Cavia porcellus (guinea pig) 128099 Chlamidomonas reinhardtii (green alga) RP38951 Caenorhabditis remanei (nematode) ENSCSAVP00000012320 Ciona savignyi (sedentary tunicate) 227483 Capitella spl (polychaete worm) DDB0214945 Dictyostelium discoideum (amoeba) DEHA2A09086g Debaryomyces Hansenii (yeast) 188575 Daphnia pulex (daphnia) ENSDARP00000072130 Danio rerio (zebra fish) ENSECAP00000021536 Equus caballus (horse) XP_650864 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000026079 Gymnopilus aculeatus (mushroom) ENSGALP00000018350 Gallus gallus (chicken) GL50803_32658 Giardia lamblia (flagellated protozoan) 107353 Hypsipyla robusta (cedar shoot borer) ENSP00000343886 Homo sapiens (human) ISCW010968-PA Ixodes scapularis (deer tick) KLLA0A08910g Kluyveromyces lactis (yeast) 186814 Lottia gigantea (owl limpet) LmjF17.0600 Leishmania major (virus) 9247 Monocosta brevicollis (choanoflagellate) ENSMODP00000012367 Monodelphis domestica (gray opossum) ENSMMUP00000030782 Macaca mulatta (rhesus monkey) ENSMUSP00000020107 Mus musculus (house mouse) 166011 Nematostella vectensis (starlet anemone) ENSOANP00000001063 Ornithorynchus anatinus (platypus) ENSORLP00000018317 Oryzias latipes (japanese killifish) LOC_Os03g10640.1 Oryza sativa (asian rice) 26194 Ostreococcus tauri (green alga) PHUM003685-PA Pediculus humanus (human body louse) PP14022 Pristionchus pacificus (nematode) 202276 Physcomitrella patens (moss) ENSPPYP00000015267 Pongo pygmaeus (orangutan) 78939 Phytophthora ramorum (sudden oak death pathogen) 108703 Phytophthora sojae (root rot pathogen) 259851 Populus trichocarpa (black cottonwood) ENSPTRP00000043371 Pan troglodytes (chimpanzee) ENSRNOP00000005491 Rattus norvegicus (norway rat) 4885617 Sorghum bicolor (sorghum) YGL006W Saccharomyces cerevisiae (budding yeast) Smp_137170 Schistosoma mansoni (trematode parasite) SPAPB2B4.04c Schizosaccharomyces pombe (fission yeast) NP_001028822.1 Strongylocentrotus purpuratus (purple sea urchin) 25320 Trichoplax adhaerens (metazoa) XP_966434.1 Tribolium castaneum (red flour beetle) Tc00.1047053509647.150 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000009500 Tetraodon nigroviridis (green spotted pufferfish) 264016 Thalassiosira pseudonana (marine diatom) ENSTRUP00000039996 Takifugu rubripes (pufferfish Takifugu) 3737.m00025 Tetrahymena thermophila (ciliate protozoa) 92349.m00292 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000007811 Xenopus tropicalis (frog) YALI0D04873g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50106 LH17220 ISCW010968 FBgn0232120 FBgn0215721 FBgn0205505 FBgn0195725 FBgn0181636 JGI_V11_188575 FBgn0243914 FBgn0155752 FBgn0136810 FBgn0131076 FBgn0108682 FBgn0098692 CPIJ005742 BGIBMGA004534 ACYPI007260 ACYPI006101 GB13865 AGAP010638 AAEL005561 PB21039 PHUM304650 GLEAN_01467
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	23306 y1; Mi{ET1}PMCAMB01085 31572 y1 v1; P{TRiP.JF01145}attP2
Harvard	- PBac{PB}PMCAc04208 - PBac{RB}PMCAe00941
VDRC	v101743 P{KK108105}VIE-260B v30203 w1118; P{GD3152}v30203
Genomic Clones ( 2 )
	BACR30L17 BACR33O09 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 274 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH04118 GM07606 IP15267
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH04478 GH04586 GH15464 HL01393 HL02469 LD15613 LP02848 RE18757 RE47903 RE48084 RE51026 RE64203 RE66879 RH01819 RH02039 RH02369 RH12375 RH51388 SD21493
Other clones	118 10506 15266 16808 18768 32238 34369 37084 41662 41782 46549 53345 53363 53535 56144 58043 58327 59723 59902 61977 62872 65342 66182 67145 74190 76003 79816 81843 83638 84163 100245 106542 107372 107520 119769 119976 121976 122748 122896 123280 125124 145380 145390 146337 147190 147229 149720 156031 156193 161711 164836 166193 173561 174258 175543 176171 192047 192552 193798 194403 194441 214249.9 214285.8 214311.8 214403.12 214405.15 214437.16 214447.17 214469.6 214473.8 214563.17 214565.1 214573.5 273879 274891 283694 473587 AM04011 CK01.13C.H10 CK01.14A.G1 CK01.16A.D3 CK01.31B.C10 CK01.32B.A6 CK01.32C.E3 CK01.36A.D11 CK01.38C.G2 CK01.59D.E4 CK01.68B.C5 CK01.72A.E7 CK01.83C.H11 CK01.84A.G4 CK01.85C.D6 CK01.89A.F1 CK01.89B.D9 CK01.93D.H1 CK01.96B.C4 CK01.98D.F3 CK01.99D.A12 CK01.101A.E9 CK01.101C.F12 CK01.101C.H2 CK01.104D.C7 CK01.105B.D12 CK01.105B.H12 CK01.107B.C2 CK01.113A.G10 CK01.116B.H2 CK01.117A.F9 CK01.123D.D10 CK01.124A.H4 CK01.130D.H4 CK01.132D.F4 CK01140 CK01914 CK02288 EC26122 EC34649 EC39280 EC40869 EC43527 EC252782 EC253693 EC257699 EK005505 EK005517 EK014461 EK029908 EK030812 EK034924 EK044707 EK048350 EK051027 EK054711 EK057120 EK066958 EK067747 EK068803 EK070021 EK070211 EK073129 EK076322 EK076736 EK077716 EK077956 EK084436 EK085316 EK085317 EK085646 EK085742 EK087712 EK089541 EK090241 EK090415 EK091536 EK091548 EK095154 EK095702 EK101254 EK105018 EK110426 EK113529 EK113605 EK118154 EK123301 EK130363 EK133517 EK136405 EK137962 EK141845 EK147841 EK149019 EK154662 EK156108 EK161515 EK165822 EK167429 EK168026 EK171046 EK171548 EK174635 EK174947 EK176325 EK179503 EK181338 EK184553 EK187029 EK188350 EK189031 EK189161 EK192034 EK195352 EK195918 EK199715 EK199858 EK208918 EK215426 EK217562 EK223050 EK225211 EK233124 EK233343 EK233351 EK233933 EK238401 EK239844 EK244562 EK245425 EK246030 EK246051 EK248606 EK248712 EK252816 EK252832 EK258837 EK258847 EK280119 EK280828 EK281706 EK294836 EK295320 EK301057 EK302710 EK308923 EN00313 EP03926 EP05711 EP09219 EP12418 EP14054 EP14854 EP16464 EP18432 EP18511 EP18826 EP18936 EP21211 EP21226 EP21333 EP21524 ESG0114d.B21_H02 FGC031B06 FGH121H01 FGH126D10 FGM303B10 FGM303E06 FGM304B02 FGM323G09 IP15367 IP15567 LD01981 LD21364 RC0-DL0001-140700-214-H07
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0259214 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43787 3885564
Antibody Information
	polyclonal (Lnenicka et al., 2006)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: CG34036 BP1021 (FlyBase Genome Annotators, 2005) Source for identity of: PMCA CG42314 (Lnenicka et al., 2006)
Source for database merge of	Source for merge of: BEST:CK01140 BEST:CK02288 CG2165 (Bayraktaroglu, 2000.11.2) Source for merge of: CG2165 CG34036 (FlyBase Genome Annotators, 2008)
Additional comments	Annotations CG2165 and CG34036 merged as CG42314 in release 5.9 of the genome annotation. (FlyBase Genome Annotators, 2008)
Other Comments
	New annotation (CG34036) in release 4.3 of the genome annotation. (FlyBase Genome Annotators, 2005) Identification: cDNA screen for secreted and transmembrane proteins expressed during embryogenesis. (Kopczynski et al., 1998)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_166754 NM_166755 NM_001014687 NM_001014688 NM_001014689 NM_001038714 NM_001201585 NM_001201586 NM_001201587 NM_001201588 NM_001201589 RefSeq (Proteins) • NP_726564 NP_726565 NP_001014687 NP_001014688 NP_001014689 NP_001033803 NP_001188514 NP_001188515 NP_001188516 NP_001188517 NP_001188518 DDBJ / EMBL / GenBank • AA141084 AA141681 AA141682 AA202486 AAF59350 AAF59350.1 AAF59350.2 AAN06528 AAN06528.1 AAN06528.2 AAX52514 AAX52515 AAX52516 ABC65829 ADV37598 ADV37599 ADV37600 ADV37601 ADV37602 AW941487 CX309645 CX309646 CZ469074 CZ471184 CZ478772 Entrez Gene - A searchable database of RefSeq genes. • 43787 UniProtKB/TrEMBL • E6EK15 E6EK17 E6EK18 Q9V4C7 Q59DP8 Q59DP9 Q59DQ0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ATPase, P-type phosphorylation site (IPR018303) ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (IPR001757) ATPase, P-type cation-transporter, N-terminal (IPR004014) ATPase, P-type cation-transporter, C-terminal (IPR006068) ATPase, P-type, calcium-transporting, PMCA-type (IPR006408) ATPase, P-type, ATPase-associated domain (IPR008250) Plasma membrane calcium transporter ATPase C-terminal (IPR022141) HAD-like domain (IPR023214) ATPase, P-type, transmembrane domain (IPR023298) ATPase, P-type, cytoplasmic domain N (IPR023299) ATPase, P-type, cytoplasmic transduction domain A (IPR023300)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68621 DroID - A comprehensive database of gene and protein interactions. • FBgn0259214 DRSC - Results from RNAi screens. • FBgn0259214 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0259214 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • HDC16691;CG2165-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0259214 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43787 3885564 InParanoid A subset of ortholog calls from InParanoid. • AAEL005561-PA Aedes aegypti (mosquito) AGAP010638-PA Anopheles gambiae (mosquito) XP_001945158.1 Acyrthosiphon pisum (pea aphid) At2g41560.1 Arabidopsis thaliana (wall cress) 35482 Batrachochytrium dendrobatidis (chytrid fungus) 110163 Branchiostoma floridae (lancelet) XP_001902371.1 Brugia malayi (roundworm nematode) BGIBMGA004534-PA Bombyx mori (silk worm) ENSBTAP00000000677 Bos taurus (bovine) CAL0000810 Candida albicans (a form of yeast) CN29319 Caenorhabditis brenneri (small nematode) CBP00914 Caenorhabditis briggsae (nematode) CE28373 Caenorhabditis elegans (worm) ENSCAFP00000007604 Canis familiaris (dog) CAGL0A00517g Candida glabrata (haploid yeast) ENSCINP00000006789 Ciona intestinalis (sea squirt) JA00949 Caenorhabditis japonica (nematode) CMQ379C Cyanidioschyzon merolae (red alga) cn04287 Cryptococcus neoformans (yeast-like fungus) CPIJ005742 Culex pipens (mosquito) ENSCPOP00000014003 Cavia porcellus (guinea pig) 128099 Chlamidomonas reinhardtii (green alga) RP38951 Caenorhabditis remanei (nematode) ENSCSAVP00000012320 Ciona savignyi (sedentary tunicate) 227483 Capitella spl (polychaete worm) DDB0214945 Dictyostelium discoideum (amoeba) DEHA2A09086g Debaryomyces Hansenii (yeast) 188575 Daphnia pulex (daphnia) ENSDARP00000072130 Danio rerio (zebra fish) ENSECAP00000021536 Equus caballus (horse) XP_650864 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000026079 Gymnopilus aculeatus (mushroom) ENSGALP00000018350 Gallus gallus (chicken) GL50803_32658 Giardia lamblia (flagellated protozoan) 107353 Hypsipyla robusta (cedar shoot borer) ENSP00000343886 Homo sapiens (human) ISCW010968-PA Ixodes scapularis (deer tick) KLLA0A08910g Kluyveromyces lactis (yeast) 186814 Lottia gigantea (owl limpet) LmjF17.0600 Leishmania major (virus) 9247 Monocosta brevicollis (choanoflagellate) ENSMODP00000012367 Monodelphis domestica (gray opossum) ENSMMUP00000030782 Macaca mulatta (rhesus monkey) ENSMUSP00000020107 Mus musculus (house mouse) 166011 Nematostella vectensis (starlet anemone) ENSOANP00000001063 Ornithorynchus anatinus (platypus) ENSORLP00000018317 Oryzias latipes (japanese killifish) LOC_Os03g10640.1 Oryza sativa (asian rice) 26194 Ostreococcus tauri (green alga) PHUM003685-PA Pediculus humanus (human body louse) PP14022 Pristionchus pacificus (nematode) 202276 Physcomitrella patens (moss) ENSPPYP00000015267 Pongo pygmaeus (orangutan) 78939 Phytophthora ramorum (sudden oak death pathogen) 108703 Phytophthora sojae (root rot pathogen) 259851 Populus trichocarpa (black cottonwood) ENSPTRP00000043371 Pan troglodytes (chimpanzee) ENSRNOP00000005491 Rattus norvegicus (norway rat) 4885617 Sorghum bicolor (sorghum) YGL006W Saccharomyces cerevisiae (budding yeast) Smp_137170 Schistosoma mansoni (trematode parasite) SPAPB2B4.04c Schizosaccharomyces pombe (fission yeast) NP_001028822.1 Strongylocentrotus purpuratus (purple sea urchin) 25320 Trichoplax adhaerens (metazoa) XP_966434.1 Tribolium castaneum (red flour beetle) Tc00.1047053509647.150 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000009500 Tetraodon nigroviridis (green spotted pufferfish) 264016 Thalassiosira pseudonana (marine diatom) ENSTRUP00000039996 Takifugu rubripes (pufferfish Takifugu) 3737.m00025 Tetrahymena thermophila (ciliate protozoa) 92349.m00292 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000007811 Xenopus tropicalis (frog) YALI0D04873g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 43787 modMine - Data generated by the modENCODE project. • FBgn0259214 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50106 LH17220 ISCW010968 FBgn0232120 FBgn0215721 FBgn0205505 FBgn0195725 FBgn0181636 JGI_V11_188575 FBgn0243914 FBgn0155752 FBgn0136810 FBgn0131076 FBgn0108682 FBgn0098692 CPIJ005742 BGIBMGA004534 ACYPI007260 ACYPI006101 GB13865 AGAP010638 AAEL005561 PB21039 PHUM304650 GLEAN_01467
Synonyms & Secondary IDs ( 12 )
Reported As
Symbol Synonym	BEST:CK (Sun et al., 2004) BEST:CK01140 (Giot et al., 2003, Sun et al., 2004) BEST:CK02288   BP1021 (Yandell et al., 2005, ) CG2165 (Roos et al., 2005, Riddle et al., 2008, Johansson et al., 2007, Bai et al., 2008, Keleman et al., 2009.8.5, Lnenicka et al., 2006, Khanna et al., 2010, Cammarato et al., 2011) CG34036 (Keleman et al., 2009.8.5) CG42314 (FlyBase Genome Annotators, 2008, Khanna et al., 2010, Ni et al., 2008) CK02288 (Kopczynski et al., 1998) PMCA (Ashton-Beaucage et al., 2010, Cammarato et al., 2011, Rui et al., 2010) unnamed (Yandell et al., 2005)
Name Synonym	CG2165   CG34036   plasma membrane Ca2+ ATPase (Lnenicka et al., 2006) plasma membrane calcium ATPase
Secondary FlyBase IDs
	FBgn0025688 FBgn0025704 FBgn0039903 FBgn0054036 FBgn0082885
References ( 39 )
Generate a list of	All references relating to this gene ( 39 )
List References by type	Research paper  ( 14 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 3 ) Computer file  ( 4 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 3 )
	Cammarato et al., 2011, PLoS ONE 6(4): e18497 A Mighty Small Heart: The Cardiac Proteome of Adult Drosophila melanogaster. [FBrf0213610] Ashton-Beaucage et al., 2010, Cell 143(2): 251--262 The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. [FBrf0212064] Rui et al., 2010, PLoS Genet. 6(11): e1001208 Sarcomere formation occurs by the assembly of multiple latent protein complexes. [FBrf0212444] Show all research papers ...