FlyBase Gene Report: Dmel\NimC1

General Information

Symbol

Dmel\NimC1

Species

D. melanogaster

Name

Nimrod C1

Annotation Symbol

CG8942

Feature Type

protein_coding_gene

FlyBase ID

FBgn0259896

Gene Model Status

Current

Stock Availability

7 publicly available

Gene Summary

EGF-like repeat transmembrane protein located on phagocytic cells - mediates resistence to bacteria (Interactive Fly, NimC1 )

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

P1, BG:DS00180.10 , nimrod

Key Links

Genomic Location

Cytogenetic map

34E5-34E5

Sequence location

2L:13,973,158..13,976,769 [-]

Recombination map

2-50

RefSeq locus

NT_033779 REGION:13973158..13976769

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (5 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (0 terms)

Biological Process (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in defense response to bacterium

inferred from mutant phenotype

(Hashimoto et al., 2009)

involved_in phagocytosis

inferred from mutant phenotype

(Hashimoto et al., 2009, Kurucz et al., 2007)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in immune response

inferred from biological aspect of ancestor with PANTHER:PTN001171370

(GO Reference Genome Project, 2011-)

involved_in phagocytosis

inferred from biological aspect of ancestor with PANTHER:PTN001171370

(GO Reference Genome Project, 2011-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in plasma membrane

inferred from direct assay

(Kurucz et al., 2007)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in membrane

inferred from sequence model

(Kurucz et al., 2007)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN004653852

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

NIMROD-TYPE RECEPTORS

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

NIMROD-TYPE RECEPTORS -: The Nimrod family of genes is characterised by the presence of NIM repeats, closely related to the EGF-repeat. They encode proteins which are secreted or integral to the plasma membrane. The Nimrod genes have been linked to the innate immune response and some members of this family have been shown to act as receptors for bacterial or apoptic cell phagocytosis. (Adapted from FBrf0212245).

Summary (Interactive Fly)

EGF-like repeat transmembrane protein located on phagocytic cells - mediates resistence to bacteria

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\NimC1 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry M9PBB4)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.42

Gene model reviewed during 5.52

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

NimC1-RA

FBtr0080615

NM_135849

2054

620

NimC1-RB

FBtr0310075

NM_001273524

2038

622

NimC1-RC

FBtr0343644

NM_001298992

2999

622

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

NimC1-PA

FBpp0080188

68.0

620

4.96

FBpp0301776

67.9

622

5.08

FBpp0310237

67.9

622

5.08

M9PBB4

NP_001285921

AHN54435

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

622 aa isoforms: NimC1-PB, NimC1-PC

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\NimC1 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.89

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

hemocyte

(Kurucz et al., 2007)

embryonic/larval lymph gland

(Kurucz et al., 2007)

embryonic/larval plasmatocyte

(Kurucz et al., 2007)

third instar larval stage

embryonic/larval plasmatocyte

(Fuwa et al., 2015, Sinenko et al., 2009)

cortical zone of lymph gland primary lobe

(Sinenko et al., 2009)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

western blot

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

hemocyte

(Kurucz et al., 2007)

Additional Descriptive Data

nimC1 protein is expressed circulating plasmatocytes at all larval stages. nimC1 is additionally expressed in larval lymph glands, sessile and circulating hemocytes, and mitotically active hemocytes. Hemocytes expressing nimC1 phagocytose bacteria and produce antimicrobial peptides. nimC1 is not expressed in embryonic hemocytes, or in cells with lamellocyte morphology.

(Kurucz et al., 2007)

Marker for

cortical zone of lymph gland primary lobe

(Sinenko et al., 2009)

embryonic/larval plasmatocyte

(Lőrincz et al., 2016, Fuwa et al., 2015, Sinenko et al., 2009)

Subcellular Localization

CV Term

Evidence

References

located_in plasma membrane

inferred from direct assay

(Kurucz et al., 2007)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\NimC1 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\NimC1

View exonic expression by tissue for Dmel\NimC1

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0259896

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34816/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0259896

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0259896

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0259896

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8942

Flygut - An atlas of the Drosophila adult midgut

FBgn0259896

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 3 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of NimC1

Transgenic constructs containing regulatory region of NimC1

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Inferred from location ( 7 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

viable, with Scer\GAL4^tin.CΔ4

Other Phenotypes

Allele

abnormal immune response, with Scer\GAL4^He.PZ

NimC1^RNAi.UAS

abnormal immune response, with Scer\GAL4^Hml.Δ

NimC1^RNAi.UAS

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

NimC1^GD2623

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (32)

Hsap\MEGF10

2 of 14

Yes

Hsap\MEGF11

2 of 14

Yes

Hsap\SCARF1

2 of 14

Yes

Hsap\STAB1

2 of 14

Yes

Hsap\STAB2

2 of 14

Yes

Hsap\CCBE1

1 of 14

Hsap\DKK1

1 of 14

Yes

Hsap\DKK2

1 of 14

Yes

Hsap\DKK3

1 of 14

Yes

Hsap\DKK4

1 of 14

Yes

Hsap\DLL1

1 of 14

Hsap\ESM1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Hsap\WIF1

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (20)

Rnor\Megf10

2 of 14

Yes

Rnor\Dkk1

1 of 14

Yes

Rnor\Dkk2

1 of 14

Yes

Rnor\Dkk3

1 of 14

Yes

Rnor\Dkk4

1 of 14

Yes

Rnor\Dner

1 of 14

Rnor\Esm1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (27)

Mmus\Megf10

2 of 14

Yes

Mmus\Megf11

2 of 14

Yes

Mmus\Pear1

2 of 14

Yes

Mmus\Ccbe1

1 of 14

Mmus\Dkk1

1 of 14

Yes

Mmus\Dkk2

1 of 14

Yes

Mmus\Dkk3

1 of 14

Yes

Mmus\Dkk4

1 of 14

Yes

Mmus\Dner

1 of 14

Mmus\Egfem1

1 of 14

Mmus\Egfl6

1 of 14

Yes

Mmus\Esm1

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (11)

Xtro\adgre2

1 of 13

Yes

Xtro\dlc

1 of 13

Yes

Xtro\egf

1 of 13

Yes

Xtro\fat1

1 of 13

Yes

Xtro\hmcn1

1 of 13

Yes

Xtro\jag1

1 of 13

Yes

Xtro\LOC101730707

1 of 13

Yes

Xtro\megf10

1 of 13

Yes

Xtro\pear1

1 of 13

Yes

Xtro\tnn

1 of 13

Yes

Xtro\vwce

1 of 13

Yes

Danio rerio (Zebrafish) (25)

Drer\megf11

2 of 14

Yes

Drer\ccbe1

1 of 14

Drer\dkk1a

1 of 14

Yes

Drer\dkk1b

1 of 14

Yes

Drer\dkk2

1 of 14

Yes

Drer\dkk3b

1 of 14

Yes

Drer\egfl6

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (43)

Cele\F07H5.8

4 of 14

Yes

Cele\F35A5.4

4 of 14

Yes

Cele\pqn-13

2 of 14

Yes

Cele\abu-1

1 of 14

Yes

Cele\abu-2

1 of 14

Yes

Cele\abu-4

1 of 14

Yes

Cele\abu-5

1 of 14

Yes

Cele\abu-6

1 of 14

Yes

Cele\abu-7

1 of 14

Yes

Cele\abu-8

1 of 14

Yes

Cele\abu-9

1 of 14

Yes

Cele\abu-10

1 of 14

Yes

Cele\abu-15

1 of 14

Yes

Cele\C53B7.2

1 of 14

Yes

Cele\ced-1

1 of 14

Cele\cpg-24

1 of 14

Yes

Cele\D1044.7

1 of 14

Cele\dsl-1

1 of 14

Yes

Cele\dsl-2

1 of 14

Yes

Cele\dsl-5

1 of 14

Yes

Cele\dsl-6

1 of 14

Yes

Cele\dsl-7

1 of 14

Yes

Cele\F46B3.15

1 of 14

Yes

Cele\F56B3.2

1 of 14

Cele\fbn-1

1 of 14

Cele\lag-2

1 of 14

Yes

Cele\M03F4.6

1 of 14

Cele\M195.2

1 of 14

Yes

Cele\pqn-2

1 of 14

Yes

Cele\pqn-25

1 of 14

Cele\pqn-54

1 of 14

Yes

Cele\pqn-57

1 of 14

Yes

Cele\pqn-71

1 of 14

Yes

Cele\pqn-76

1 of 14

Yes

Cele\pqn-78

1 of 14

Yes

Cele\pqn-79

1 of 14

Yes

Cele\pqn-90

1 of 14

Yes

Cele\pqn-91

1 of 14

Yes

Cele\sdz-23

1 of 14

Yes

Cele\T01D3.1

1 of 14

Cele\ten-1

1 of 14

Cele\Y5H2A.4

1 of 14

Yes

Cele\Y64G10A.7

1 of 14

Anopheles gambiae (African malaria mosquito) (13)

Agam\AgaP_AGAP009763

4 of 12

Yes

3 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:NimC1. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (22)

5 of 13

5 of 13

5 of 13

4 of 13

4 of 13

4 of 13

4 of 13

4 of 13

4 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

dpy

1 of 13

frac

1 of 13

Sgs4

1 of 13

shf

1 of 13

Ten-a

1 of 13

Ten-m

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

RNA-protein

Physical Interaction

Assay

References

NimC1 - Arc1

anti bait coimmunoprecipitation, full identification by RNA sequencing, quantitative reverse transcription pcr

(Xiao et al., 2023)

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

60845

DroID - A comprehensive database of gene and protein interactions.

FBgn0259896

MIST (protein-protein) - An integrated Molecular Interaction Database

34816

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

Class of Gene

gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-50

Cytogenetic map

34E5-34E5

Sequence location

2L:13,973,158..13,976,769 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

34E5-34E5

Limits computationally determined from genome sequence between P{lacW}Sos^k05224&P{lacW}RpII33^k05605 and P{lacW}l(2)34Fa^k00811&P{PZ}wb⁰⁹⁴³⁷

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-50

(FlyBase, 2016)

2-45.3

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

25787

y¹ v¹; P{TRiP.JF01793}attP2

59190

y¹ w^*; Mi{MIC}NimC1^MI13732

NIG-Fly

8942R-3

P{NIG.8942R}3

2LG-1449

y² VhaAC39-1^cho-1 v¹; P{U6-NimC1.NIG.sgRNA}attP40/CyO

VDRC

v105799

P{KK110957}VIE-260B

v1031

w¹¹¹⁸; P{GD127}v1031

v342770

P{hsFLP}1, y1 w1118; P{HD_CFD01765}attP40/CyO-GFP

Genomic Clones (17)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (3)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

LP05465

Other clones

FI17857

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0259896

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

IP14207

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0259896

Antibody Information

Laboratory Generated Antibodies

monoclonal

(Kurucz et al., 2007)

Commercially Available Antibodies

Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

S2 cells transfected with dsRNA made from templates generated with primers directed against this gene show normal levels of phagocytosis of bacteria.

(Kocks et al., 2005)

Silencing of nimrod by dsRNS-mediated interference resulted in a reduction of phagocytosis of FITC labeled Staphylococcus aureus bacteria. Ectopic expression of nimrod in negative cell lines resulted in a dramatic increase of phagocytosis of both FITC labeled Staphylococcus aureus and E. coli bacteria.

(Kurucz et al., 2005)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: nimC1 CG8942

(Kurucz et al., 2007)

Source for identity of: NimC1 nimC1

(FlyBase, 2009-)

Nomenclature comments

Etymology

The "nimrod" gene cluster is dubbed after Nimrod, the biblical "mighty hunter before the Lord" (Genesis 10), who according to Gesta Hungarorum was also the ancestor of all Hungarians (Kezai Simon, Gesta Hunnorum et Hungarorum A.D. 1282).

(Kurucz et al., 2007)

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

BG:DS00180.10

(Giot et al., 2003, Parra et al., 2000, Ashburner et al., 1999, Ashburner et al., 1999, Ashburner et al., 1999.10.12)

CG8942

(National Institute of Genetics Fly Stocks, 2022-, Okuda et al., 2016, Palu and Thummel, 2016, Japanese National Institute of Genetics, 2012.5.21, Wertheim et al., 2011, Fernández-Ayala et al., 2010, Schirling et al., 2010, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15, Bhutkar et al., 2008, Kwon et al., 2008, Ranade et al., 2008, Junion et al., 2007, Kurucz et al., 2007, Betz and Darnell, 2006, Dierick and Greenspan, 2006, Tolhuis et al., 2006, Kocks et al., 2005, Rehwinkel et al., 2005)

CT25688

(Hynes and Zhao, 2000)

Nim

(Cordero et al., 2010)

NimC

(Obbard et al., 2009)

NimC1

(Dolgikh et al., 2025, Hirooka et al., 2025, Hersperger et al., 2024, Krejčová et al., 2024, Monticelli et al., 2024, Salminen et al., 2024, Tsap et al., 2024, Cai et al., 2023, Chen et al., 2023, Khalili et al., 2023, Krejčová et al., 2023, Voutyraki et al., 2023, Hultmark and Andó, 2022, Kharrat et al., 2022, Liegeois and Ferrandon, 2022, Shrivastava et al., 2022, Cattenoz et al., 2021, Csordás et al., 2021, Girard et al., 2021, Madi et al., 2021, Mohr et al., 2021, Petrignani et al., 2021, Cho et al., 2020, Lu et al., 2020, Park et al., 2020, Araki et al., 2019, Kurelac et al., 2019, Melcarne et al., 2019, Melcarne et al., 2019, Paddibhatla et al., 2019, Hao et al., 2018, Yu et al., 2018, Lőrincz et al., 2016, Parsons and Foley, 2016, Vanha-Aho et al., 2015, Vlisidou and Wood, 2015, Woodcock et al., 2015, Evans et al., 2014, Honti et al., 2014, Wang et al., 2014, Honti et al., 2013, Shravage et al., 2013, Bras et al., 2012, Longworth et al., 2012, Fauvarque and Williams, 2011, Hyrsl et al., 2011, Avet-Rochex et al., 2010, Cordero et al., 2010, Honti et al., 2010, Márkus et al., 2009, Somogyi et al., 2008, Kurucz et al., 2007)

Nimrod C1

(Ramond et al., 2020)

(Yu et al., 2021, Khadilkar et al., 2020, Khadilkar et al., 2014, Avet-Rochex et al., 2010, Cordero et al., 2010, Kurucz et al., 2007)

nimC1

(Xiao et al., 2023, Kopp and Park, 2019, Aradska et al., 2015, Izutsu et al., 2012, Bernard et al., 2010, Somogyi et al., 2010, Charroux and Royet, 2009, Ye et al., 2009, Pastor-Pareja et al., 2008, Kurucz et al., 2007, Sackton et al., 2007)

nimrod

nimrod C1

(Sciambra and Chtarbanova, 2021)

Name Synonyms

CG8942

Nimrod C1

(Parsons and Foley, 2016, Kounatidis and Ligoxygakis, 2012, Cordero et al., 2010)

NimrodC1

(Marcetteau et al., 2025, Shravage et al., 2013)

nimrod

(Sinenko et al., 2010, Charroux and Royet, 2009, Kurucz et al., 2005)

nimrod C1

(Radyuk et al., 2012, Hashimoto et al., 2009, Kurucz et al., 2007, Sackton et al., 2007)

nimrodC1

(Ou et al., 2011, Charroux and Royet, 2009)

Secondary FlyBase IDs

FBgn0028545
FBgn0027847
FBgn0083073

Datasets (0)

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External Crossreferences and Linkouts ( 44 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

34816

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

M9PBB4

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

M9PBB4

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0259896

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

34816/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0259896

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0259896

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG8942

MARRVEL_MODEL - MARRVEL (model organism gene)

34816

Linkouts

BioGRID - A database of protein and genetic interactions.

60845

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0259896

DroID - A comprehensive database of gene and protein interactions.

FBgn0259896

DRSC - Results frm RNAi screens

FBgn0259896

Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0259896

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0259896

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8942

Flygut - An atlas of the Drosophila adult midgut

FBgn0259896

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

34816

References (134)

The following external sites may use different assemblies or annotations than FlyBase.

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