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Gene Dmel\pds5

General Information
Symbol	Dmel\pds5	Species	D. melanogaster
Name		Annotation symbol	CG17509
Feature type	protein_coding_gene	FlyBase ID	FBgn0260012
Gene Model Status	Current	Stock availability	8 publicly available
Also Known As	dPds5
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	48D7-48D6	Sequence location	2R:7,915,484..7,921,230 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\pds5 (CG17509, FBgn0260012). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding. There is experimental evidence that it is involved in the biological process: chromosome segregation; sister chromatid cohesion; karyosome formation. 15 alleles are reported. The phenotypes of these alleles are annotated with: mitotic cohesin complex; salivary gland; trichogen cell; polytene chromosome; condensed chromosome; imaginal disc; embryonic/larval brain. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1623138_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of pds5. Gene sequence location is 2R:7915484..7921230.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA06670 BKN21976
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 48D7-48D6   Limits computationally determined from genome sequence between P{lacW}l(2)k06612k06612 and P{lacW}jebk05644; Left limit from in situ hybridisation (FBrf0067338) Right limit from in situ hybridisation (FBrf0067338)
Experimentally Determined Cytological Location
Cytogenetic map Notes References 48D5-48D6   (determined by in situ hybridisation)   (Spradling et al., 1999) 48D5-48D6     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\pds5 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone GH12788 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) pds5-RA FBtr0087974  NM_136875   4677   1218 pds5-RB FBtr0306062     4935   1218
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein pds5-PA   FBpp0087082   138.9   1218   7.68     NP_610719   AAF58593 pds5-PB   FBpp0297204   138.9   1218   7.68
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Armadillo-type fold (IPR016024) Armadillo-like helical (IPR011989)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263284   AA439547   AA697570   AA820330   AE013599 AAF58593   AI062649   AI064123   AI134891   AI135147   AI386679   AI530941   AI532316   AI532561   AI534657   AW940480   AX094059   AY058358 AAL13587   BF486377   BF493766   BG636450   BG636509   BG637099   BI172559   BI355367   BI362687   BI362872   BI638201   BI638672   BI641079   BP541005   BP546023   BT053744   CL527902   CO154189   CO177658   CO188724   CO189404   CO269750   CO271308   CO288619   CO295079   CO300569   CO312256   CO313971   CO316573   CO329862   CO335802   CO336828   CO342502   EC058179   EC064798   EC080644   EC214085   EC224800   EC229986   EC232091   EC246078   EC249849   EC250726   EC252317   EC260943   EC262266   EC266038
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95U25 A1Z8S6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0260012    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0260012 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0260012 expression level Developmental Stage   Expression Level embryo 00-02hr    3556 embryo 02-04hr    2206 embryo 04-06hr    2245 embryo 06-08hr    1766 embryo 08-10hr    1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day    2459 adult female 30day    2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3556) embryo 02-04hr  (2206) embryo 04-06hr  (2245) embryo 06-08hr  (1766) embryo 08-10hr  (1442) embryo 10-12hr  (998) embryo 12-14hr  (887) embryo 14-16hr  (618) embryo 16-18hr  (554) embryo 18-20hr  (508) embryo 20-22hr  (679) embryo 22-24hr  (838) larva L1  (797) larva L2  (661) larva L3 12hr old  (553) larva L3 puffstage 1-2  (531) larva L3 puffstage 3-6  (854) larva L3 puffstage 7-9  (1050) white prepupae new  (1057) white prepupae 12hr  (1118) white prepupae 24hr  (1202) pupae 2d postWPP  (800) pupae 3d postWPP  (502) pupae 4d postWPP  (476) adult male 01day  (541) adult male 05day  (600) adult male 30day  (570) adult female 01day  (1158) adult female 05day  (2459) adult female 30day  (2374) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3556) embryo 02-04hr  (2206) embryo 04-06hr  (2245) embryo 06-08hr  (1766) embryo 08-10hr  1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day  (2459) adult female 30day  (2374) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3556 embryo 02-04hr    2206 embryo 04-06hr    2245 embryo 06-08hr    1766 embryo 08-10hr    1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day    2459 adult female 30day    2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3556 embryo 02-04hr    2206 embryo 04-06hr    2245 embryo 06-08hr    1766 embryo 08-10hr    1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day    2459 adult female 30day    2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0260012 expression level Developmental Stage   Expression Level embryo 00-02hr    3556 embryo 02-04hr    2206 embryo 04-06hr    2245 embryo 06-08hr    1766 embryo 08-10hr    1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day    2459 adult female 30day    2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3556) embryo 02-04hr  (2206) embryo 04-06hr  (2245) embryo 06-08hr  (1766) embryo 08-10hr  (1442) embryo 10-12hr  (998) embryo 12-14hr  (887) embryo 14-16hr  (618) embryo 16-18hr  (554) embryo 18-20hr  (508) embryo 20-22hr  (679) embryo 22-24hr  (838) larva L1  (797) larva L2  (661) larva L3 12hr old  (553) larva L3 puffstage 1-2  (531) larva L3 puffstage 3-6  (854) larva L3 puffstage 7-9  (1050) white prepupae new  (1057) white prepupae 12hr  (1118) white prepupae 24hr  (1202) pupae 2d postWPP  (800) pupae 3d postWPP  (502) pupae 4d postWPP  (476) adult male 01day  (541) adult male 05day  (600) adult male 30day  (570) adult female 01day  (1158) adult female 05day  (2459) adult female 30day  (2374) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3556) embryo 02-04hr  2206 embryo 04-06hr  2245 embryo 06-08hr  1766 embryo 08-10hr  1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day  2459 adult female 30day  2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3556 embryo 02-04hr    2206 embryo 04-06hr    2245 embryo 06-08hr    1766 embryo 08-10hr    1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day    2459 adult female 30day    2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3556 embryo 02-04hr    2206 embryo 04-06hr    2245 embryo 06-08hr    1766 embryo 08-10hr    1442 embryo 10-12hr    998 embryo 12-14hr    887 embryo 14-16hr    618 embryo 16-18hr    554 embryo 18-20hr    508 embryo 20-22hr    679 embryo 22-24hr    838 larva L1    797 larva L2    661 larva L3 12hr old    553 larva L3 puffstage 1-2    531 larva L3 puffstage 3-6    854 larva L3 puffstage 7-9    1050 white prepupae new    1057 white prepupae 12hr    1118 white prepupae 24hr    1202 pupae 2d postWPP    800 pupae 3d postWPP    502 pupae 4d postWPP    476 adult male 01day    541 adult male 05day    600 adult male 30day    570 adult female 01day    1158 adult female 05day    2459 adult female 30day    2374 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0260012    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0260012 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0260012 expression level Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary    535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary  535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary    535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary    535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0260012 expression level Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary    535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary  535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary    535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    344.425 Larval Midgut    95.8 Larval Hindgut    138.4 Larval Malpighian Tubules    117.2 Larval Fat Body    101.7 Larval Salivary Gland    140.3 Larval Trachea    109.35 Larval Carcass    106.85 Adult Head    89.9 Adult Eye    67.025 Adult Brain    199.3 Adult Thoracic-Abdominal Ganglion    169.4 Adult Crop    156.5 Adult Midgut    89.9 Adult Hindgut    102.5 Adult Malpighian Tubules    66.4 Adult Fat Body    174 Adult Salivary Gland    111.9 Adult Heart    100.7 Adult VirginFemale Spermatheca    176.9 Adult InseminatedFemale Spermatheca    208.4 Adult Ovary    535 Adult Testis    48.8 Adult Male Accessory Gland    194 Adult Carcass    91.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    89.9   NA  Eye    67.025   NA  Brain    199.3   344.425  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    169.4   NA  Crop    156.5   95.8  Midgut    89.9   138.4  Hindgut    102.5   117.2  Malpighian Tubules    66.4   101.7  Fat Body    174   140.3  Salivary Gland    111.9   NA  Heart    100.7   109.35  Trachea    NA   NA  VirginFemale Spermatheca    176.9   NA  InseminatedFemale Spermatheca    208.4   NA  Ovary    535   NA  Testis    48.8   NA  Male Accessory Gland    194   106.85  Carcass    91.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_13
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0260012 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17509-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | recessive pds5k13312 lethal | third instar larval stage pds5e3 pds5e6 lethal | third instar larval stage (with pds5e3) pds5e6 lethal | third instar larval stage (with pds5e6) pds5e3 semi-lethal | recessive pds5k13312 viable pds5EY06473 viable, with Scer\GAL4pnr-MD237 pds5GD14795 Sterility Allele fertile pds5EY06473 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 pds5GD14795 Phenotype manifest in Allele chorion | germline clone pds51 pds52 pds53 pds54 pds55 pds56 pds57 pds58 condensed chromosome pds5e3 pds5e6 dorsal appendage | germline clone pds51 embryonic/larval brain pds5e3 pds5e6 embryonic/larval brain (with pds5e3) pds5e6 embryonic/larval brain (with pds5e6) pds5e3 imaginal disc pds5e3 pds5e6 imaginal disc (with pds5e3) pds5e6 imaginal disc (with pds5e6) pds5e3 karyosome | germline clone pds52 mitotic cohesin complex pds5e3 pds5e6 mitotic cohesin complex (with pds5e3) pds5e6 mitotic cohesin complex (with pds5e6) pds5e3 polytene chromosome pds5e3 pds5e6 salivary gland pds5e3 pds5e6 trichogen cell, with Scer\GAL4pnr-MD237 pds5GD14795
Classical Alleles ( 12 )
For All Classical Alleles Show
Allele of pds5 Class Mutagen Stocks Known lesion pds5k13312 P-element activity 2 -- pds5e3 Delta2-3 1 Yes pds5e6 Delta2-3 1 Yes pds5EY06473 P-element activity 1 -- pds51 ethyl methanesulfonate 0 -- pds52 ethyl methanesulfonate 0 -- pds53 ethyl methanesulfonate 0 -- pds54 ethyl methanesulfonate 0 -- pds55 ethyl methanesulfonate 0 -- pds56 ethyl methanesulfonate 0 -- pds57 ethyl methanesulfonate 0 -- pds58 ethyl methanesulfonate 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of pds5 Class Mutagen Stocks Known lesion pds5GD14795 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes pds5GL00479 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes pds5Chi.T:Avic\GFP-EGFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Not disrupted in	Df(2R)vg135 (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14795} NA P{TRiP.GL00479} NA characterization construct P{Chi-pds5-EGFP} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}pds5EY06473 NA insertion of enhancer trap P{lacW}pds5k13312 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
chromosome segregation inferred from mutant phenotype (Dorsett et al., 2005) karyosome formation inferred from mutant phenotype (Barbosa et al., 2007) sister chromatid cohesion inferred from mutant phenotype (Dorsett et al., 2005)
Cellular Component
CV term Evidence References
colocalizes_with cohesin complex inferred from direct assay (Gause et al., 2008) nucleus inferred from direct assay (Gause et al., 2008) polytene chromosome inferred from direct assay (Gause et al., 2008)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene (Garcia et al., 2007, ) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions pds5 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0260012 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36286
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12284 Dere\GG20237 Dgri\GH20852 Dper\GL10519 Dpse\GA14533 Dsec\GM21325 Dsim\GD10832 Dvir\GJ20678 Dwil\GK21335 Dyak\GE12396
Curated drosophilid orthologs	Dpse\GA14533
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL014212-PA Aedes aegypti (mosquito) AGAP010643-PA Anopheles gambiae (mosquito) XP_623860.1 Apis mellifera (honey bee) XP_001942856.1 Acyrthosiphon pisum (pea aphid) At5g47690.1 Arabidopsis thaliana (wall cress) 92704 Batrachochytrium dendrobatidis (chytrid fungus) 117138 Branchiostoma floridae (lancelet) 63712 Branchiostoma floridae (lancelet) XP_001895635.1 Brugia malayi (roundworm nematode) BGIBMGA004379-PA Bombyx mori (silk worm) ENSBTAP00000015410 Bos taurus (bovine) CAL0006191 Candida albicans (a form of yeast) CN03966 Caenorhabditis brenneri (small nematode) CBP19152 Caenorhabditis briggsae (nematode) CE33526 Caenorhabditis elegans (worm) ENSCAFP00000009540 Canis familiaris (dog) CAGL0J01507g Candida glabrata (haploid yeast) ENSCINP00000026055 Ciona intestinalis (sea squirt) JA11965 Caenorhabditis japonica (nematode) CMQ352C Cyanidioschyzon merolae (red alga) cn10267 Cryptococcus neoformans (yeast-like fungus) CPIJ007978 Culex pipens (mosquito) ENSCPOP00000010398 Cavia porcellus (guinea pig) 146572 Chlamidomonas reinhardtii (green alga) RP37614 Caenorhabditis remanei (nematode) ENSCSAVP00000004063 Ciona savignyi (sedentary tunicate) 19210 Capitella spl (polychaete worm) DDB0217729 Dictyostelium discoideum (amoeba) DEHA2F19646g Debaryomyces Hansenii (yeast) 57300 Daphnia pulex (daphnia) ENSDARP00000081680 Danio rerio (zebra fish) ENSECAP00000017592 Equus caballus (horse) ENSGACP00000027173 Gymnopilus aculeatus (mushroom) ENSGALP00000027519 Gallus gallus (chicken) 62692 Hypsipyla robusta (cedar shoot borer) ENSP00000383329 Homo sapiens (human) KLLA0F25806g Kluyveromyces lactis (yeast) 32239 Monocosta brevicollis (choanoflagellate) ENSMODP00000012039 Monodelphis domestica (gray opossum) ENSMMUP00000009451 Macaca mulatta (rhesus monkey) ENSMUSP00000016569 Mus musculus (house mouse) 157977 Nematostella vectensis (starlet anemone) XP_001602270.1 Nasonia vitripennis (wasp) ENSOANP00000024381 Ornithorynchus anatinus (platypus) ENSORLP00000004547 Oryzias latipes (japanese killifish) LOC_Os06g17840.1 Oryza sativa (asian rice) PHUM005102-PA Pediculus humanus (human body louse) 146270 Physcomitrella patens (moss) ENSPPYP00000006002 Pongo pygmaeus (orangutan) 76281 Phytophthora ramorum (sudden oak death pathogen) 157033 Phytophthora sojae (root rot pathogen) 254645 Populus trichocarpa (black cottonwood) ENSPTRP00000009824 Pan troglodytes (chimpanzee) ENSRNOP00000001464 Rattus norvegicus (norway rat) 4897322 Sorghum bicolor (sorghum) SPAC110.02 Schizosaccharomyces pombe (fission yeast) XP_790621.2 Strongylocentrotus purpuratus (purple sea urchin) 56191 Trichoplax adhaerens (metazoa) XP_968906.1 Tribolium castaneum (red flour beetle) ENSTNIP00000008169 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000031251 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000037051 Xenopus tropicalis (frog) YALI0E12969g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15121 NV15914 LH24198 FBgn0230141 FBgn0223327 FBgn0207816 FBgn0182595 FBgn0176206 JGI_V11_57300 FBgn0074561 FBgn0148129 FBgn0143691 FBgn0128314 FBgn0112428 FBgn0089321 CPIJ007978 BGIBMGA004379 ACYPI006488 GB14093 AGAP010643 AAEL014212 PHUM550980 GLEAN_09599
Stocks & Reagents
Stocks Listed in FlyBase ( 8 )
Bloomington	16725 y1 w67c23; P{EPgy2}pds5EY06473 11080 y1 w67c23; P{lacW}pds5k13312/CyO 26163 y1 w*; pds5e6/CyO-Df(2R)B80, y+ 35632 y1 sc* v1; P{TRiP.GL00479}attP2/TM3, Sb1 26162 y1 w*; pds5e3/CyO, P{GAL4-Kr.C}DC3, P{UAS-GFP.S65T}DC7
Kyoto	102866 y1 w67c23 ; P{lacW}pds5k13312 / CyO
VDRC	v36528 w1118 P{GD14795}v36528 v36527 w1118; P{GD14795}v36527
Genomic Clones ( 2 )
	BACR04E21 BACR14L19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 58 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH12788 RE40483
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02113 AT20658 GH01934 GH04388 GH12466 GH16841 GM30547 HL02802 LD06375 LD14143 LD23891 RE15083 RE47310 RE47549 SD01735 SD03779 SD04108 SD07592 SD14169 SD14240 SD14959 SD20434 SD21026 SD24205
Other clones	57722 81424 101351 108148 161556 191411 214511.26 523235 542747 561887 CK01.50D.D3 CK01.61D.E10 CK01.66D.C3 CK01.168A.H4 EK041714 EK044208 EK054010 EK069003 EK095805 EK102947 EK178619 EK208607 EK228259 EK234538 EK265316 EK294043 EN03661 EN11237 EN13324 EP15026 FGA009G07 FGH102A06
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0260012 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36286 47450
Antibody Information
	polyclonal (Gause et al., 2008)
Other Information
Discoverer
Etymology
	The gene is named "cohiba", after a brand of Cuban cigars, due to the mutant eggshell phenotype. (Barbosa et al., 2007)
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: pds5 CG17509 (Dorsett et al., 2005)
Source for database merge of	Source for merge of: CG17509 anon-WO0118547.183 (FlyBase, 1996-) Source for merge of: pds5 Pds5 l(2)k13312 (Barbosa et al., 2007)
Additional comments	Source for merge of CG17509 anon-WO0118547.183 was sequence comparison (date:051113). (FlyBase, 1996-)
Other Comments
	Area matching Drosophila ESTS AI064123 and AA263284 (inverted). (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136875 RefSeq (Proteins) • NP_610719 DDBJ / EMBL / GenBank • AA263284 AAF58593 AAL13587 AI064123 AI135147 AI532561 AW940480 AX094059 AY058358 CL527902 Entrez Gene - A searchable database of RefSeq genes. • 36286 UniProtKB/TrEMBL • A1Z8S6 Q95U25
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Armadillo-type fold (IPR016024) Armadillo-like helical (IPR011989)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0260012 DRSC - Results from RNAi screens. • FBgn0260012 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0260012 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17509-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0260012 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36286 47450 InParanoid A subset of ortholog calls from InParanoid. • AAEL014212-PA Aedes aegypti (mosquito) AGAP010643-PA Anopheles gambiae (mosquito) XP_623860.1 Apis mellifera (honey bee) XP_001942856.1 Acyrthosiphon pisum (pea aphid) At5g47690.1 Arabidopsis thaliana (wall cress) 92704 Batrachochytrium dendrobatidis (chytrid fungus) 117138 Branchiostoma floridae (lancelet) 63712 Branchiostoma floridae (lancelet) XP_001895635.1 Brugia malayi (roundworm nematode) BGIBMGA004379-PA Bombyx mori (silk worm) ENSBTAP00000015410 Bos taurus (bovine) CAL0006191 Candida albicans (a form of yeast) CN03966 Caenorhabditis brenneri (small nematode) CBP19152 Caenorhabditis briggsae (nematode) CE33526 Caenorhabditis elegans (worm) ENSCAFP00000009540 Canis familiaris (dog) CAGL0J01507g Candida glabrata (haploid yeast) ENSCINP00000026055 Ciona intestinalis (sea squirt) JA11965 Caenorhabditis japonica (nematode) CMQ352C Cyanidioschyzon merolae (red alga) cn10267 Cryptococcus neoformans (yeast-like fungus) CPIJ007978 Culex pipens (mosquito) ENSCPOP00000010398 Cavia porcellus (guinea pig) 146572 Chlamidomonas reinhardtii (green alga) RP37614 Caenorhabditis remanei (nematode) ENSCSAVP00000004063 Ciona savignyi (sedentary tunicate) 19210 Capitella spl (polychaete worm) DDB0217729 Dictyostelium discoideum (amoeba) DEHA2F19646g Debaryomyces Hansenii (yeast) 57300 Daphnia pulex (daphnia) ENSDARP00000081680 Danio rerio (zebra fish) ENSECAP00000017592 Equus caballus (horse) ENSGACP00000027173 Gymnopilus aculeatus (mushroom) ENSGALP00000027519 Gallus gallus (chicken) 62692 Hypsipyla robusta (cedar shoot borer) ENSP00000383329 Homo sapiens (human) KLLA0F25806g Kluyveromyces lactis (yeast) 32239 Monocosta brevicollis (choanoflagellate) ENSMODP00000012039 Monodelphis domestica (gray opossum) ENSMMUP00000009451 Macaca mulatta (rhesus monkey) ENSMUSP00000016569 Mus musculus (house mouse) 157977 Nematostella vectensis (starlet anemone) XP_001602270.1 Nasonia vitripennis (wasp) ENSOANP00000024381 Ornithorynchus anatinus (platypus) ENSORLP00000004547 Oryzias latipes (japanese killifish) LOC_Os06g17840.1 Oryza sativa (asian rice) PHUM005102-PA Pediculus humanus (human body louse) 146270 Physcomitrella patens (moss) ENSPPYP00000006002 Pongo pygmaeus (orangutan) 76281 Phytophthora ramorum (sudden oak death pathogen) 157033 Phytophthora sojae (root rot pathogen) 254645 Populus trichocarpa (black cottonwood) ENSPTRP00000009824 Pan troglodytes (chimpanzee) ENSRNOP00000001464 Rattus norvegicus (norway rat) 4897322 Sorghum bicolor (sorghum) SPAC110.02 Schizosaccharomyces pombe (fission yeast) XP_790621.2 Strongylocentrotus purpuratus (purple sea urchin) 56191 Trichoplax adhaerens (metazoa) XP_968906.1 Tribolium castaneum (red flour beetle) ENSTNIP00000008169 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000031251 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000037051 Xenopus tropicalis (frog) YALI0E12969g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36286 modMine - Data generated by the modENCODE project. • FBgn0260012 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB15121 NV15914 LH24198 FBgn0230141 FBgn0223327 FBgn0207816 FBgn0182595 FBgn0176206 JGI_V11_57300 FBgn0074561 FBgn0148129 FBgn0143691 FBgn0128314 FBgn0112428 FBgn0089321 CPIJ007978 BGIBMGA004379 ACYPI006488 GB14093 AGAP010643 AAEL014212 PHUM550980 GLEAN_09599
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	anon-WO0118547.183   CG17509 (Barbosa et al., 2007, Dorsett et al., 2005, Ogura et al., 2009, Gause et al., 2008, Ni et al., 2011.7.19) dPds5 (Barbosa et al., 2007, Garcia et al., 2007) l(2)k13312 (Barbosa et al., 2007, ) pds5 (Dorsett et al., 2005, Hallson et al., 2008, Gause et al., 2010) Pds5 (Gause et al., 2008)
Name Synonym	CG17509   cohiba (Garcia et al., 2007, Barbosa et al., 2007) lethal (2) k13312   pds5
Secondary FlyBase IDs
	FBgn0021887 FBgn0033676 FBgn0062185 FBgn0086756
References ( 20 )
Research paper	Gause et al., 2010, Mol. Cell. Biol. 30(20): 4940--4951 Dosage-sensitive regulation of Cohesin chromosome binding and dynamics by Nipped-B, Pds5, and Wapl. [FBrf0211896] Ogura et al., 2009, Radiat. Res. 171(1): 1--8 Reduction in Mutation Frequency by Very Low-Dose Gamma Irradiation of Drosophila melanogaster Germ Cells. [FBrf0206576] Gause et al., 2008, Chromosoma 117(1): 51--66 Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells. [FBrf0203143] Hallson et al., 2008, Proc. Natl. Acad. Sci. U.S.A. 105(34): 12405--12410 The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) protein. [FBrf0205879] Barbosa et al., 2007, Genetics 176(4): 1967--1977 A maternal screen for genes regulating Drosophila oocyte polarity uncovers new steps in meiotic progression. [FBrf0200974] Dorsett et al., 2005, Development 132(21): 4743--4753 Effects of sister chromatid cohesion proteins on cut gene expression during wing development in Drosophila. [FBrf0190284] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Conference report	Garcia et al., 2007, Fly 1(2): 125--131 Cell cycle regulation. [FBrf0200076]
Patent	Davies et al., 2001, World Patent 0118547: Essential genes and assays relating thereto. [FBrf0199103]
DNA/RNA sequence record	Davies, 2001.3.15, GenBank/EMBL/DDBJ: AX094059 Sequence 183 from Patent WO0118547. [FBrf0149872]
Computer file	Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078] BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]