General Information Symbol Dmel\ CG42507Species D. melanogaster Name Annotation symbol CG42507 Feature type protein_coding_gene FlyBase ID FBgn0260233 Gene Model Status Current Stock availability 1 publicly
available Genomic Location Chromosome (arm) 3L Recombination map Cytogenetic map 70F4-70F4 Sequence location 3L:14,741,029..14,751,062 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG42507 (FBgn0260233). It is a protein_coding_gene from
Drosophila melanogaster . Its
molecular function is unknown. The
biological processes in which it is involved are not known.
2 alleles are reported . No phenotypic data is available. It has
2 annotated transcripts and
2 annotated polypeptides . Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages. This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene. The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult thoracico-abdominal ganglion, larval/adult salivary gland, larval trachea, adult ovary, larval carcass. Gene sequence location is
3L:14741029..14751062 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.46
gene_with_dicistronic_mRNA ; SO:0000722
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Comment: reported as muscle system primordium
Comment: reported as muscle system primordium
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
184
central nervous system, pupae P8
59
head, virgin 1-day female
45
head, virgin 4-day female
49
head, virgin 20-day female
32
head, mated 1-day female
44
head, mated 4-day female
56
head, mated 20-day female
31
head, mated 1-day male
63
head, mated 4-day male
61
head, mated 20-day male
66
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
35
fat body, pupae P8
49
carcass, larvae L3 wandering
86
carcass, 1-day adult
29
carcass, 4-day adult
38
carcass, 20-day adult
31
ovary, virgin 4-day female
66
ovary, mated 4-day female
90
testis, mated 4-day male
44
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(105)
central nervous system, larvae L3
(184)
central nervous system, pupae P8
(59)
head, virgin 1-day female
(45)
head, virgin 4-day female
(49)
head, virgin 20-day female
(32)
head, mated 1-day female
(44)
head, mated 4-day female
(56)
head, mated 20-day female
(31)
head, mated 1-day male
(63)
head, mated 4-day male
(61)
head, mated 20-day male
(66)
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
(35)
fat body, pupae P8
(49)
carcass, larvae L3 wandering
(86)
carcass, 1-day adult
(29)
carcass, 4-day adult
(38)
carcass, 20-day adult
(31)
ovary, virgin 4-day female
(66)
ovary, mated 4-day female
(90)
testis, mated 4-day male
(44)
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
(184)
central nervous system, pupae P8
59
head, virgin 1-day female
45
head, virgin 4-day female
49
head, virgin 20-day female
32
head, mated 1-day female
44
head, mated 4-day female
56
head, mated 20-day female
31
head, mated 1-day male
63
head, mated 4-day male
61
head, mated 20-day male
66
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
35
fat body, pupae P8
49
carcass, larvae L3 wandering
86
carcass, 1-day adult
29
carcass, 4-day adult
38
carcass, 20-day adult
31
ovary, virgin 4-day female
66
ovary, mated 4-day female
90
testis, mated 4-day male
44
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
184
central nervous system, pupae P8
59
head, virgin 1-day female
45
head, virgin 4-day female
49
head, virgin 20-day female
32
head, mated 1-day female
44
head, mated 4-day female
56
head, mated 20-day female
31
head, mated 1-day male
63
head, mated 4-day male
61
head, mated 20-day male
66
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
35
fat body, pupae P8
49
carcass, larvae L3 wandering
86
carcass, 1-day adult
29
carcass, 4-day adult
38
carcass, 20-day adult
31
ovary, virgin 4-day female
66
ovary, mated 4-day female
90
testis, mated 4-day male
44
accessory gland, mated 4-day male
20
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
184
central nervous system, pupae P8
59
head, virgin 1-day female
45
head, virgin 4-day female
49
head, virgin 20-day female
32
head, mated 1-day female
44
head, mated 4-day female
56
head, mated 20-day female
31
head, mated 1-day male
63
head, mated 4-day male
61
head, mated 20-day male
66
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
35
fat body, pupae P8
49
carcass, larvae L3 wandering
86
carcass, 1-day adult
29
carcass, 4-day adult
38
carcass, 20-day adult
31
ovary, virgin 4-day female
66
ovary, mated 4-day female
90
testis, mated 4-day male
44
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(105)
central nervous system, larvae L3
(184)
central nervous system, pupae P8
(59)
head, virgin 1-day female
(45)
head, virgin 4-day female
(49)
head, virgin 20-day female
32
head, mated 1-day female
(44)
head, mated 4-day female
(56)
head, mated 20-day female
31
head, mated 1-day male
(63)
head, mated 4-day male
(61)
head, mated 20-day male
(66)
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
(35)
fat body, pupae P8
(49)
carcass, larvae L3 wandering
(86)
carcass, 1-day adult
29
carcass, 4-day adult
(38)
carcass, 20-day adult
31
ovary, virgin 4-day female
(66)
ovary, mated 4-day female
(90)
testis, mated 4-day male
(44)
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
(184)
central nervous system, pupae P8
59
head, virgin 1-day female
45
head, virgin 4-day female
49
head, virgin 20-day female
32
head, mated 1-day female
44
head, mated 4-day female
56
head, mated 20-day female
31
head, mated 1-day male
63
head, mated 4-day male
61
head, mated 20-day male
66
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
35
fat body, pupae P8
49
carcass, larvae L3 wandering
86
carcass, 1-day adult
29
carcass, 4-day adult
38
carcass, 20-day adult
31
ovary, virgin 4-day female
66
ovary, mated 4-day female
90
testis, mated 4-day male
44
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
105
central nervous system, larvae L3
184
central nervous system, pupae P8
59
head, virgin 1-day female
45
head, virgin 4-day female
49
head, virgin 20-day female
32
head, mated 1-day female
44
head, mated 4-day female
56
head, mated 20-day female
31
head, mated 1-day male
63
head, mated 4-day male
61
head, mated 20-day male
66
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
21
digestive system, larvae L3 wandering
23
digestive system, 1-day adult
18
digestive system, 4-day adult
22
digestive system, 20-day adult
18
fat body, larvae L3 wandering
16
fat body, white prepupae
35
fat body, pupae P8
49
carcass, larvae L3 wandering
86
carcass, 1-day adult
29
carcass, 4-day adult
38
carcass, 20-day adult
31
ovary, virgin 4-day female
66
ovary, mated 4-day female
90
testis, mated 4-day male
44
accessory gland, mated 4-day male
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
81
embryo 04-06hr
69
embryo 06-08hr
116
embryo 08-10hr
95
embryo 10-12hr
110
embryo 12-14hr
90
embryo 14-16hr
80
embryo 16-18hr
54
embryo 18-20hr
47
embryo 20-22hr
39
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
33
larva L3 puffstage 7-9
33
white prepupae new
34
white prepupae 12hr
35
white prepupae 24hr
53
pupae 2d postWPP
36
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
33
adult female 05day
28
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(45)
embryo 02-04hr
(81)
embryo 04-06hr
(69)
embryo 06-08hr
(116)
embryo 08-10hr
(95)
embryo 10-12hr
(110)
embryo 12-14hr
(90)
embryo 14-16hr
(80)
embryo 16-18hr
(54)
embryo 18-20hr
(47)
embryo 20-22hr
(39)
embryo 22-24hr
(31)
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
(33)
larva L3 puffstage 7-9
(33)
white prepupae new
(34)
white prepupae 12hr
(35)
white prepupae 24hr
(53)
pupae 2d postWPP
(36)
pupae 3d postWPP
(27)
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
(32)
adult female 01day
(33)
adult female 05day
(28)
adult female 30day
(31)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
81
embryo 04-06hr
69
embryo 06-08hr
(116)
embryo 08-10hr
95
embryo 10-12hr
(110)
embryo 12-14hr
90
embryo 14-16hr
80
embryo 16-18hr
54
embryo 18-20hr
47
embryo 20-22hr
39
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
33
larva L3 puffstage 7-9
33
white prepupae new
34
white prepupae 12hr
35
white prepupae 24hr
53
pupae 2d postWPP
36
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
33
adult female 05day
28
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
81
embryo 04-06hr
69
embryo 06-08hr
116
embryo 08-10hr
95
embryo 10-12hr
110
embryo 12-14hr
90
embryo 14-16hr
80
embryo 16-18hr
54
embryo 18-20hr
47
embryo 20-22hr
39
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
33
larva L3 puffstage 7-9
33
white prepupae new
34
white prepupae 12hr
35
white prepupae 24hr
53
pupae 2d postWPP
36
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
33
adult female 05day
28
adult female 30day
31
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
81
embryo 04-06hr
69
embryo 06-08hr
116
embryo 08-10hr
95
embryo 10-12hr
110
embryo 12-14hr
90
embryo 14-16hr
80
embryo 16-18hr
54
embryo 18-20hr
47
embryo 20-22hr
39
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
33
larva L3 puffstage 7-9
33
white prepupae new
34
white prepupae 12hr
35
white prepupae 24hr
53
pupae 2d postWPP
36
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
33
adult female 05day
28
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(45)
embryo 02-04hr
(81)
embryo 04-06hr
(69)
embryo 06-08hr
(116)
embryo 08-10hr
(95)
embryo 10-12hr
(110)
embryo 12-14hr
(90)
embryo 14-16hr
(80)
embryo 16-18hr
(54)
embryo 18-20hr
(47)
embryo 20-22hr
(39)
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
(33)
larva L3 puffstage 7-9
(33)
white prepupae new
(34)
white prepupae 12hr
(35)
white prepupae 24hr
(53)
pupae 2d postWPP
(36)
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
(33)
adult female 05day
28
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
81
embryo 04-06hr
69
embryo 06-08hr
116
embryo 08-10hr
95
embryo 10-12hr
110
embryo 12-14hr
90
embryo 14-16hr
80
embryo 16-18hr
54
embryo 18-20hr
47
embryo 20-22hr
39
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
33
larva L3 puffstage 7-9
33
white prepupae new
34
white prepupae 12hr
35
white prepupae 24hr
53
pupae 2d postWPP
36
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
33
adult female 05day
28
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
45
embryo 02-04hr
81
embryo 04-06hr
69
embryo 06-08hr
116
embryo 08-10hr
95
embryo 10-12hr
110
embryo 12-14hr
90
embryo 14-16hr
80
embryo 16-18hr
54
embryo 18-20hr
47
embryo 20-22hr
39
embryo 22-24hr
31
larva L1
23
larva L2
24
larva L3 12hr old
18
larva L3 puffstage 1-2
19
larva L3 puffstage 3-6
33
larva L3 puffstage 7-9
33
white prepupae new
34
white prepupae 12hr
35
white prepupae 24hr
53
pupae 2d postWPP
36
pupae 3d postWPP
27
pupae 4d postWPP
23
adult male 01day
23
adult male 05day
26
adult male 30day
32
adult female 01day
33
adult female 05day
28
adult female 30day
31
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
91
Schneider line 2 Sg4
65
embryonic 1182-4H
66
embryonic GM2
40
embryonic Kc167
15
embryonic S1
90
embryonic S3
70
leg disc CME L1
89
wing disc CME-W2
37
wing disc ML-DmD8
57
wing disc ML-DmD9
102
wing disc ML-DmD16-c3
88
wing disc ML-DmD21
154
wing disc ML-DmD32
67
haltere disc ML-DmD17-c3
92
eye-antennal disc ML-DmD11
54
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
71
CNS ML-DmBG2-c2
46
tumorous blood cells mbn2
41
ovary fGS/OSS
245
ovary OSC
74
ovary OSS
86
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(91)
Schneider line 2 Sg4
(65)
embryonic 1182-4H
(66)
embryonic GM2
(40)
embryonic Kc167
15
embryonic S1
(90)
embryonic S3
(70)
leg disc CME L1
(89)
wing disc CME-W2
(37)
wing disc ML-DmD8
(57)
wing disc ML-DmD9
(102)
wing disc ML-DmD16-c3
(88)
wing disc ML-DmD21
(154)
wing disc ML-DmD32
(67)
haltere disc ML-DmD17-c3
(92)
eye-antennal disc ML-DmD11
(54)
antennal disc ML-DmD20-c5
(34)
mixed discs ML-DmD4-c1
(85)
CNS ML-DmBG1-c1
(71)
CNS ML-DmBG2-c2
(46)
tumorous blood cells mbn2
(41)
ovary fGS/OSS
(245)
ovary OSC
(74)
ovary OSS
(86)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
91
Schneider line 2 Sg4
65
embryonic 1182-4H
66
embryonic GM2
40
embryonic Kc167
15
embryonic S1
90
embryonic S3
70
leg disc CME L1
89
wing disc CME-W2
37
wing disc ML-DmD8
57
wing disc ML-DmD9
102
wing disc ML-DmD16-c3
88
wing disc ML-DmD21
(154)
wing disc ML-DmD32
67
haltere disc ML-DmD17-c3
92
eye-antennal disc ML-DmD11
54
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
71
CNS ML-DmBG2-c2
46
tumorous blood cells mbn2
41
ovary fGS/OSS
(245)
ovary OSC
74
ovary OSS
86
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
91
Schneider line 2 Sg4
65
embryonic 1182-4H
66
embryonic GM2
40
embryonic Kc167
15
embryonic S1
90
embryonic S3
70
leg disc CME L1
89
wing disc CME-W2
37
wing disc ML-DmD8
57
wing disc ML-DmD9
102
wing disc ML-DmD16-c3
88
wing disc ML-DmD21
154
wing disc ML-DmD32
67
haltere disc ML-DmD17-c3
92
eye-antennal disc ML-DmD11
54
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
71
CNS ML-DmBG2-c2
46
tumorous blood cells mbn2
41
ovary fGS/OSS
245
ovary OSC
74
ovary OSS
86
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
91
Schneider line 2 Sg4
65
embryonic 1182-4H
66
embryonic GM2
40
embryonic Kc167
15
embryonic S1
90
embryonic S3
70
leg disc CME L1
89
wing disc CME-W2
37
wing disc ML-DmD8
57
wing disc ML-DmD9
102
wing disc ML-DmD16-c3
88
wing disc ML-DmD21
154
wing disc ML-DmD32
67
haltere disc ML-DmD17-c3
92
eye-antennal disc ML-DmD11
54
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
71
CNS ML-DmBG2-c2
46
tumorous blood cells mbn2
41
ovary fGS/OSS
245
ovary OSC
74
ovary OSS
86
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(91)
Schneider line 2 Sg4
(65)
embryonic 1182-4H
(66)
embryonic GM2
(40)
embryonic Kc167
15
embryonic S1
(90)
embryonic S3
(70)
leg disc CME L1
(89)
wing disc CME-W2
(37)
wing disc ML-DmD8
(57)
wing disc ML-DmD9
(102)
wing disc ML-DmD16-c3
(88)
wing disc ML-DmD21
(154)
wing disc ML-DmD32
(67)
haltere disc ML-DmD17-c3
(92)
eye-antennal disc ML-DmD11
(54)
antennal disc ML-DmD20-c5
(34)
mixed discs ML-DmD4-c1
(85)
CNS ML-DmBG1-c1
(71)
CNS ML-DmBG2-c2
(46)
tumorous blood cells mbn2
(41)
ovary fGS/OSS
(245)
ovary OSC
(74)
ovary OSS
(86)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
91
Schneider line 2 Sg4
65
embryonic 1182-4H
66
embryonic GM2
40
embryonic Kc167
15
embryonic S1
90
embryonic S3
70
leg disc CME L1
89
wing disc CME-W2
37
wing disc ML-DmD8
57
wing disc ML-DmD9
102
wing disc ML-DmD16-c3
88
wing disc ML-DmD21
(154)
wing disc ML-DmD32
67
haltere disc ML-DmD17-c3
92
eye-antennal disc ML-DmD11
54
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
71
CNS ML-DmBG2-c2
46
tumorous blood cells mbn2
41
ovary fGS/OSS
(245)
ovary OSC
74
ovary OSS
86
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
91
Schneider line 2 Sg4
65
embryonic 1182-4H
66
embryonic GM2
40
embryonic Kc167
15
embryonic S1
90
embryonic S3
70
leg disc CME L1
89
wing disc CME-W2
37
wing disc ML-DmD8
57
wing disc ML-DmD9
102
wing disc ML-DmD16-c3
88
wing disc ML-DmD21
154
wing disc ML-DmD32
67
haltere disc ML-DmD17-c3
92
eye-antennal disc ML-DmD11
54
antennal disc ML-DmD20-c5
34
mixed discs ML-DmD4-c1
85
CNS ML-DmBG1-c1
71
CNS ML-DmBG2-c2
46
tumorous blood cells mbn2
41
ovary fGS/OSS
245
ovary OSC
74
ovary OSS
86
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
94
cold shock, 4-day adult
66
heat shock, 4-day adult
44
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
45
Cadmium 100 mM 48 hrs, 4-day adult
77
Copper 0.5 mM 12 hrs, larvae L3
63
Copper 15 mM 48 hrs, 4-day adult
47
Zinc 5 mM 12 hrs, larvae L3
55
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
64
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
72
Caffeine 25 mg/ml 48 hrs, 4-day adult
78
Paraquat 5 mM 48 hrs, 4-day adult
65
Paraquat 10 mM 48 hrs, 4-day adult
57
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(94)
cold shock, 4-day adult
(66)
heat shock, 4-day adult
(44)
Cadmium 50 mM 6 hrs, larvae L3
(28)
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
(45)
Cadmium 100 mM 48 hrs, 4-day adult
(77)
Copper 0.5 mM 12 hrs, larvae L3
(63)
Copper 15 mM 48 hrs, 4-day adult
(47)
Zinc 5 mM 12 hrs, larvae L3
(55)
Zinc 4.5 mM 48 hrs, 4-day adult
(56)
Ethanol 2.5% 3 hrs, larvae L3
(64)
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(72)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(78)
Paraquat 5 mM 48 hrs, 4-day adult
(65)
Paraquat 10 mM 48 hrs, 4-day adult
(57)
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
94
cold shock, 4-day adult
66
heat shock, 4-day adult
44
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
45
Cadmium 100 mM 48 hrs, 4-day adult
77
Copper 0.5 mM 12 hrs, larvae L3
63
Copper 15 mM 48 hrs, 4-day adult
47
Zinc 5 mM 12 hrs, larvae L3
55
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
64
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
72
Caffeine 25 mg/ml 48 hrs, 4-day adult
78
Paraquat 5 mM 48 hrs, 4-day adult
65
Paraquat 10 mM 48 hrs, 4-day adult
57
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
94
cold shock, 4-day adult
66
heat shock, 4-day adult
44
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
45
Cadmium 100 mM 48 hrs, 4-day adult
77
Copper 0.5 mM 12 hrs, larvae L3
63
Copper 15 mM 48 hrs, 4-day adult
47
Zinc 5 mM 12 hrs, larvae L3
55
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
64
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
72
Caffeine 25 mg/ml 48 hrs, 4-day adult
78
Paraquat 5 mM 48 hrs, 4-day adult
65
Paraquat 10 mM 48 hrs, 4-day adult
57
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
94
cold shock, 4-day adult
66
heat shock, 4-day adult
44
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
45
Cadmium 100 mM 48 hrs, 4-day adult
77
Copper 0.5 mM 12 hrs, larvae L3
63
Copper 15 mM 48 hrs, 4-day adult
47
Zinc 5 mM 12 hrs, larvae L3
55
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
64
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
72
Caffeine 25 mg/ml 48 hrs, 4-day adult
78
Paraquat 5 mM 48 hrs, 4-day adult
65
Paraquat 10 mM 48 hrs, 4-day adult
57
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(94)
cold shock, 4-day adult
(66)
heat shock, 4-day adult
(44)
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
(45)
Cadmium 100 mM 48 hrs, 4-day adult
(77)
Copper 0.5 mM 12 hrs, larvae L3
(63)
Copper 15 mM 48 hrs, 4-day adult
(47)
Zinc 5 mM 12 hrs, larvae L3
(55)
Zinc 4.5 mM 48 hrs, 4-day adult
(56)
Ethanol 2.5% 3 hrs, larvae L3
(64)
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(72)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(78)
Paraquat 5 mM 48 hrs, 4-day adult
(65)
Paraquat 10 mM 48 hrs, 4-day adult
(57)
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
94
cold shock, 4-day adult
66
heat shock, 4-day adult
44
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
45
Cadmium 100 mM 48 hrs, 4-day adult
77
Copper 0.5 mM 12 hrs, larvae L3
63
Copper 15 mM 48 hrs, 4-day adult
47
Zinc 5 mM 12 hrs, larvae L3
55
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
64
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
72
Caffeine 25 mg/ml 48 hrs, 4-day adult
78
Paraquat 5 mM 48 hrs, 4-day adult
65
Paraquat 10 mM 48 hrs, 4-day adult
57
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
94
cold shock, 4-day adult
66
heat shock, 4-day adult
44
Cadmium 50 mM 6 hrs, larvae L3
28
Cadmium 50 mM 12 hrs, larvae L3
19
Cadmium 50 mM 48 hrs, 4-day adult
45
Cadmium 100 mM 48 hrs, 4-day adult
77
Copper 0.5 mM 12 hrs, larvae L3
63
Copper 15 mM 48 hrs, 4-day adult
47
Zinc 5 mM 12 hrs, larvae L3
55
Zinc 4.5 mM 48 hrs, 4-day adult
56
Ethanol 2.5% 3 hrs, larvae L3
64
Ethanol 5% 3 hrs, larvae L3
20
Ethanol 10% 3 hrs, larvae L3
26
Caffeine 1.5 mg/ml 4 hrs, larvae L3
20
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
72
Caffeine 25 mg/ml 48 hrs, 4-day adult
78
Paraquat 5 mM 48 hrs, 4-day adult
65
Paraquat 10 mM 48 hrs, 4-day adult
57
Rotenone 2 μg 12 hrs, larvae L3
20
Rotenone 8 μg 12 hrs, larvae L3
23
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 2 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 0 ) For All Alleles Carried on Transgenic
Constructs Show Allele of
CG42507 Class Mutagen Stocks Known lesion
Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 0 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 0 terms ) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A comprehensive database of gene and protein interactions.
Orthologs
OrthoDB Orthologs (7)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG6JDHTK )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (0)
based on analysis using Dmel annotation version 4.3
Stocks & Reagents Stocks Listed in FlyBase ( 1 )Bloomington Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 111 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments One or more of the processed transcripts for this gene contain(s) two non-overlapping open reading frames (ORFs). The non-overlapping ORFs are represented by
Trl and
CG42507 .
Other Comments New annotation (CG42507) in release 5.13 of the genome annotation.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 1 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 8 )Supplementary material Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Personal communication to FlyBase Bellen, 2012.9.7, set1005.xmlset1005.xml [FBrf0219418] Brody, 2009.03, Possible annotation changes flagged by EvoPrintingPossible annotation changes flagged by EvoPrinting [FBrf0207435] Myrick et al., 2008.12.2, Alignment of P{wHy} collection to current genome.Alignment of P{wHy} collection to current genome. [FBrf0206273] FlyBase analysis FlyBase Genome Annotators, 2008, Changes affecting gene model number or type in release 5.13 of the annotated D.melanogaster genome.Changes affecting gene model number or type in release 5.13 of the annotated D.melanogaster genome. [FBrf0205930] FlyBase, 1992-, FlyBase curation.FlyBase curation. [FBrf0105495] Website Fisher et al., 2012, BDGP insitu homepageBDGP insitu homepage [FBrf0219073]