dLsd1, Lsd1, Suvar(3)3, Su-var(3)3, Histone demethylase
homolog of the human LSD1 amine oxidase - demethylates H3K4me2 and H3K4me1 and facilitates subsequent H3K9 methylation by SU(VAR)3-9 - dictates the distinction between euchromatic and heterochromatic domains during early embryogenesis
Gene model reviewed during 5.43
Gene model reviewed during 5.45
Component of a complex that contains at least HDAC1/Rpd3, CoRest and Su(var)3-3/Hdm.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Su(var)3-3 using the Feature Mapper tool.
Su(var)3-3 is expressed uniformly throughout the developing wing in both vein and intervein cells in stage P7 pupal wings.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Su(var)3-3 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Hdm CG17149
Source for merge of: Su(var)3-3 Hdm
The "Su(var)3-3" gene was previously mistakenly merged with the CG17147 gene in FlyBase. This error has been corrected and CG17147 has been split out into a separate gene from Su(var)3-3. The "Su(var)3-3" gene actually corresponds to the "CG17149" annotation.
No additive effect of mutant alleles with mod alleles on suppression of position effect variegation at In(1)wm4.