dmp
homolog of Collagen XV/XVIII, a matrix protein that can be proteolytically cleaved to release Endostatin, an antiangiogenesis signaling factor - required for normal calcium channel abundance, presynaptic calcium influx, and neurotransmitter release - functions in motor axon pathfinding
Please see the GBrowse view of Dmel\Mp or the JBrowse view of Dmel\Mp for information on other features
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merge of CG33171 and CG8647
Gene model reviewed during 5.41
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Mp using the Feature Mapper tool.
Mp expression is observed starting at embryonic stage 16 in the dorsal vessel, aorta, filzkorper, central nervous system, especially in the neuropil region. No isoform-specific expression was observed.
In late embryos, Mp is specifically localized at the heart lumen, but not at the cardioblast basal domain. The Mp antibody does not detect staining at the aorta domain, nor in the pair of ostia cells. Importantly, Mp was only detected in cardioblasts at the stage of tube formation, and not in earlier stages.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Mp in GBrowse 23-19
3-19
3-15.9
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
Source for identity of: mp CG42543
Source for identity of: Mp mp
Source for merge of: CG33171 CG8647
Source for merge of: CG8645 CG14822
Annotations CG33171 and CG8647 merged as CG42543 in release 5.15 of the genome annotation.
Annotations CG8645 and CG14822 merged as CG33171 in release 3 of the genome annotation.
