Gene Dmel\mp

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Laminin G domain (IPR001791)

Collagen triple helix repeat (IPR008160)

Collagenase NC10/endostatin (IPR010515)

C-type lectin-like (IPR016186)

C-type lectin fold (IPR016187)

Concanavalin A-like lectin/glucanases superfamily (IPR008985)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

(The modENCODE Consortium, 2010, Graveley et al., 2011)

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at high levels in the following post-embryonic organs or tissues: adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval central nervous system, larval hindgut, adult heart, larval trachea, adult testis, larval carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		57
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		(57)
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		57
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		57
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		57
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		(57)
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		57
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		5
central nervous system, larvae L3		8
central nervous system, pupae P8		57
head, virgin 1-day female		7
head, virgin 4-day female		6
head, virgin 20-day female		5
head, mated 1-day female		6
head, mated 4-day female		5
head, mated 20-day female		5
head, mated 1-day male		10
head, mated 4-day male		9
head, mated 20-day male		11
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		3
digestive system, 1-day adult		0
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		11
carcass, larvae L3 wandering		13
carcass, 1-day adult		3
carcass, 4-day adult		3
carcass, 20-day adult		2
ovary, virgin 4-day female		2
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		0
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		7
embryo 16-18hr		20
embryo 18-20hr		23
embryo 20-22hr		14
embryo 22-24hr		15
larva L1		14
larva L2		6
larva L3 12hr old		6
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		6
larva L3 puffstage 7-9		10
white prepupae new		18
white prepupae 12hr		25
white prepupae 24hr		17
pupae 2d postWPP		21
pupae 3d postWPP		19
pupae 4d postWPP		11
adult male 01day		8
adult male 05day		5
adult male 30day		5
adult female 01day		6
adult female 05day		2
adult female 30day		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		0
embryonic 1182-4H		0
embryonic GM2		8
embryonic Kc167		1
embryonic S1		0
embryonic S3		2
leg disc CME L1		0
wing disc CME-W2		0
wing disc ML-DmD8		1
wing disc ML-DmD9		0
wing disc ML-DmD16-c3		1
wing disc ML-DmD21		0
wing disc ML-DmD32		0
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		1
antennal disc ML-DmD20-c5		0
mixed discs ML-DmD4-c1		4
CNS ML-DmBG1-c1		9
CNS ML-DmBG2-c2		9
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		4
heat shock, 4-day adult		2
Cadmium 50 mM 6 hrs, larvae L3		2
Cadmium 50 mM 12 hrs, larvae L3		2
Cadmium 50 mM 48 hrs, 4-day adult		2
Cadmium 100 mM 48 hrs, 4-day adult		2
Copper 0.5 mM 12 hrs, larvae L3		2
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		2
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		2
Ethanol 5% 3 hrs, larvae L3		3
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		2
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		2
Caffeine 25 mg/ml 48 hrs, 4-day adult		3
Paraquat 5 mM 48 hrs, 4-day adult		3
Paraquat 10 mM 48 hrs, 4-day adult		5
Rotenone 2 μg 12 hrs, larvae L3		2
Rotenone 8 μg 12 hrs, larvae L3		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

External Data & Images

developmental rate defective

BDGP expression data

•

GH14382

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0260660

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

viable, with Scer\GAL4^pnr-MD237

Sterility

Allele

fertile

Other Phenotypes

Allele

body color defective, with Scer\GAL4^pnr-MD237

mp^GD6041

neuroanatomy defective | embryonic stage

neuroanatomy defective | embryonic stage, with Scer\GAL4^how-24B

mp^{ES.Scer\UAS.T:SS-wg}

touch sensitivity defective | larval stage

visible

mp^f07253

visible, with Scer\GAL4^pnr-MD237

mp^GD6041

visible (with mp^f03008)

mp^f07253

visible (with mp^f07253)

mp^f03008

Phenotype manifest in

Allele

chordotonal organ

mp^f07253

embryonic/larval fat body

intersegmental nerve, with Scer\GAL4^how-24B

mp^{ES.Scer\UAS.T:SS-wg}

intersegmental nerve branch ISNb of A1-7

intersegmental nerve branch ISNb of A1-7, with Scer\GAL4^how-24B

mp^{ES.Scer\UAS.T:SS-wg}

lipid particle

mesothoracic tergum, with Scer\GAL4^pnr-MD237

mp^GD6041

presumptive embryonic/larval nervous system, with Scer\GAL4^how-24B

mp^{ES.Scer\UAS.T:SS-wg}

tergite

tergite (with mp^f03008)

mp^f07253

tergite (with mp^f07253)

mp^f03008

trichogen cell, with Scer\GAL4^pnr-MD237

mp^GD6041

wing vein

mp^f07253

wing vein (with mp^f03008)

mp^f07253

wing vein (with mp^f07253)

mp^f03008

Classical Alleles ( 9 )

For All Classical Alleles Show

Allele of mp	Mutagen	Stocks	Known lesion
mp^f07253	piggyBac transposase	2	--
mp^c01251		1	--
mp^DG37705	P-element activity	1	--
mp^f03008	piggyBac transposase	1	--
mp^MB01109		1	--
mp^MB08228		1	--
mp^MI04509		1	--
mp^ΔC12-25	FLPase	0	Yes
mp^ΔN4-11	FLPase	0	Yes

Alleles Carried on Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Allele of mp	Mutagen	Stocks	Known lesion
mp^GD6041	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
mp^GD12529	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mp^JF02929	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mp^KK103713	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mp^KK108613	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mp^{3hNC1.Scer\UAS}	in vitro construct - regulatory fusion	0	Yes
mp^{ES.Scer\UAS.T:SS-wg}	in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
mp^{NC1.Scer\UAS.T:SS-wg}	in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
mp^NIG.8647R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

Mi{MIC}mp^MI04509

P{wHy}mp^DG37705

PBac{PB3.WH3}mp^ΔC12-25

PBac{PB}mp^c01251

PBac{WH}mp^f03008

PBac{WH}mp^f07253

insertion of enhancer trap binary system

Mi{ET1}mp^MB01109

Mi{ET1}mp^MB08228

insertion of mobile activating element

PBac{WHr}mp^ΔN4-11

Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )

Terms Based on Experimental Evidence ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

motor neuron axon guidance

References

inferred from mutant phenotype

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 5 terms )

Molecular Function

CV term

structural molecule activity

References

carbohydrate binding

inferred from sequence or structural similarity with Lectin-galC1

(Tanji et al., 2006)

inferred from electronic annotation with InterPro:IPR003129, InterPro:IPR010515

(FlyBase Curators et al., 2004-)

Biological Process

CV term

(FlyBase Curators et al., 2004-)

References

cell adhesion

inferred from electronic annotation with InterPro:IPR003129, InterPro:IPR010515

Cellular Component

CV term

(FlyBase Curators et al., 2004-)

References

collagen

inferred from sequence or structural similarity

(Hynes and Zhao, 2000)

extracellular matrix

inferred from electronic annotation with InterPro:IPR010515

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

mp allele

Gene

References

External Data

y¹ v¹; P{TRiP.JF02929}attP2

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0260660

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

38769

Orthologs

OrthoDB Orthologs (54) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG65MNR2

Dipteran inclusive ortholog search

EOG6V9V02

Insect inclusive ortholog search

EOG66DJZ2

Arthropod inclusive ortholog search

EOG6VT4CH

Metazoa inclusive ortholog search

EOG67DP8M

Orthologs in Drosophila Species (EOG65MNR2)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA23588

Drosophila persimilis

Dper\GL25020

Drosophila willistoni

Dwil\GK16646

Drosophila virilis

Dvir\GJ13132

Drosophila mojavensis

Dmoj\GI12990

Drosophila grimshawi

Dgri\GH15385

Orthologs in non-Drosophila Dipterans (EOG6V9V02)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL002256

Anopheles gambiae

Malaria mosquito

Agam\AGAP006516

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ005619

Orthologs in non-Dipteran Insects (EOG66DJZ2)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB47258

Apis mellifera

Western honey bee

Amel\GB47257

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG014386

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH19932

Atta cephalotes

Leafcutter ant

Acep\ACEP22246

Atta cephalotes

Leafcutter ant

Acep\ACEP22249

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO15871

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL16893

Linepithema humile

Argentine ant

Lhum\LH25877

Linepithema humile

Argentine ant

Lhum\LH20456

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB23443

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB23441

Solenopsis invicta

Red fire ant

Sinv\SINV21629

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI27470

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI49091

Bombyx mori

Silkmoth

Bmor\BGIBMGA012062

Bombyx mori

Silkmoth

Bmor\BGIBMGA012067

Pediculus humanus

Human body louse

Phum\PHUM321580

Tribolium castaneum

Red flour beetle

Tcas\TC003787

Tribolium castaneum

Red flour beetle

Tcas\TC003786

Orthologs in non-Insect Arthropods (EOG6VT4CH)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\Serpind1

Daphnia pulex

Water flea

Dpux\accD

Daphnia pulex

Water flea

Dpux\JGI_V11_48458

Orthologs in non-Arthropod Metazoa (EOG67DP8M)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\cle-1

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_025559gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_000142gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_012707gn

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_026786gn

Danio rerio

Zebrafish

Drer\col18a1

Danio rerio

Zebrafish

Drer\col15a1b

Xenopus tropicalis

Western clawed frog

Xtro\col18a1-prov

Gallus gallus

Domestic chicken

Ggal\COL15A1

Gallus gallus

Domestic chicken

Ggal\COL18A1

Mus musculus

House mouse

Mmus\Col15a1

Mus musculus

House mouse

Mmus\ENSMUSG00000001435

Rattus norvegicus

Norway rat

Rnor\ENSRNOG00000001229

Rattus norvegicus

Norway rat

Rnor\ENSRNOG00000039197

Homo sapiens

Human

Hsap\COL15A1

Homo sapiens

Human

Hsap\ENSG00000182871

Human Orthologs (2)

Gene

OMIM

HGNC

Hsap\COL15A1

Hsap\ENSG00000182871

AAA Orthologs (22) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila simulans

Drosophila sechellia

Drosophila sechellia

Drosophila erecta

Drosophila erecta

Drosophila yakuba

Drosophila yakuba

Drosophila ananassae

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA21236

Drosophila pseudoobscura pseudoobscura

Dpse\GA23588

Drosophila persimilis

Dper\GL25019

Drosophila persimilis

Dper\GL25020

Drosophila willistoni

Dwil\GK16645

Drosophila willistoni

Dwil\GK16646

Drosophila virilis

Dvir\GJ13131

Drosophila virilis

Dvir\GJ13132

Drosophila mojavensis

Dmoj\GI12989

Drosophila mojavensis

Dmoj\GI12990

Drosophila grimshawi

Dgri\GH15384

Drosophila grimshawi

Dgri\GH15385

Stocks & Reagents

Stocks Listed in FlyBase ( 14 )

Bloomington

19062

w¹¹¹⁸; PBac{WH}mp^f07253

25289

w¹¹¹⁸; Mi{ET1}mp^MB08228

28299

37696

y¹ w^*; Mi{MIC}mp^MI04509

v100846

v107319

v38188

w¹¹¹⁸; P{GD6041}v38188

v38189

w¹¹¹⁸; P{GD6041}v38189

v35431

w¹¹¹⁸; P{GD12529}v35431

More stocks available...

Genomic Clones ( 1 )

BACR21K18

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 48 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

DRSC - Results from RNAi screens.

•

FBgn0260660

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

38769

Antibody Information

polyclonal

(Momota et al., 2011)

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for identity of: mp CG42543

(FlyBase Genome Annotators, 2002-2003)

Source for database merge of

Source for merge of: CG8645 CG14822

Source for merge of: CG33171 CG8647

(FlyBase Genome Annotators, 2009)

Additional comments

Annotations CG33171 and CG8647 merged as CG42543 in release 5.15 of the genome annotation.

(FlyBase Genome Annotators, 2009)

Annotations CG8645 and CG14822 merged as CG33171 in release 3 of the genome annotation.

(FlyBase Genome Annotators, 2002-2003)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

RefSeq (Proteins)

•

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

38769

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Laminin G domain (IPR001791)

Collagen triple helix repeat (IPR008160)

Collagenase NC10/endostatin (IPR010515)

C-type lectin-like (IPR016186)

C-type lectin fold (IPR016187)

Concanavalin A-like lectin/glucanases superfamily (IPR008985)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

GH14382

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0260660

DRSC - Results from RNAi screens.

•

FBgn0260660

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0260660

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0260660

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

38769

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

38769

modMine - Data generated by the modENCODE project.

•

FBgn0260660

Synonyms & Secondary IDs ( 11 )

Reported As

Symbol Synonym

CG8645

(Sano et al., 2005)

CG8647

(Momota et al., 2011, Meyer and Moussian, 2009, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)

CG14822

CG33171

(Momota et al., 2011, Tanji et al., 2006, Kwon et al., 2008, Meyer and Moussian, 2009, Keleman et al., 2009.8.5, Perkins et al., 2009, Cammarato et al., 2011)

CG42543

(FlyBase Genome Annotators, 2009, Gilliland et al., 2009)

COL18A1

(Grossman et al., 2011)

CT14872

(Hynes and Zhao, 2000)

Dmp

(Momota et al., 2011, Kaushik et al., 2012)

Name Synonym

CG8647

CG33171

Collagen-like

(Sano et al., 2005)

multiplexin