FlyBase Gene Report: Dmel\ctrip

General Information

Symbol

Dmel\ctrip

Species

D. melanogaster

Name

circadian trip

Annotation Symbol

CG42574

Feature Type

protein_coding_gene

FlyBase ID

FBgn0260794

Gene Model Status

Current

Stock Availability

18 publicly available

Gene Snapshot

circadian trip (ctrip) encodes a HECT ubiquitin ligase that regulates the levels and circadian oscillations of the transcriptional activator encoded by Clk. It plays a role in the control of rest-activity rhythms. [Date last reviewed: 2019-03-07]

Other Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

82D5-82D6

Sequence location

3R:4,786,284..4,812,096 [-]

Recombination map

3-47.1

RefSeq locus

NT_033777 REGION:4786284..4812096

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (11 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables ubiquitin protein ligase activity

inferred from sequence or structural similarity with UniProtKB:Q14669

(assigned by UniProt )

(UniProt Curators, 2002-)

enables ubiquitin-protein transferase activity

inferred from sequence or structural similarity with HGNC:12306

(FlyBase Curators, 2008--)

enables zinc ion binding

inferred from electronic annotation with InterPro:IPR018123

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

Biological Process (6 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

involved_in positive regulation of circadian rhythm

inferred from mutant phenotype

(Lamaze et al., 2011)

involved_in positive regulation of protein catabolic process

inferred from mutant phenotype

(Lamaze et al., 2011)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

involved_in cellular response to DNA damage stimulus

inferred from biological aspect of ancestor with PANTHER:PTN000134292

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in negative regulation of histone H2A K63-linked ubiquitination

inferred from biological aspect of ancestor with PANTHER:PTN000134292

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in regulation of double-strand break repair

inferred from biological aspect of ancestor with PANTHER:PTN000134292

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in ubiquitin-dependent protein catabolic process

inferred from biological aspect of ancestor with PANTHER:PTN000134292

(assigned by GO_Central )

(Gaudet et al., 2011)

inferred from sequence or structural similarity with HGNC:12306

(FlyBase Curators, 2008--)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

located_in nuclear speck

inferred from biological aspect of ancestor with PANTHER:PTN000134292

(assigned by GO_Central )

(Gaudet et al., 2011)

located_in nucleus

inferred from sequence or structural similarity with HGNC:12306

(FlyBase Curators, 2008--)

Gene Group (FlyBase)

HECT UBIQUITIN LIGASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Group (FlyBase)

HECT UBIQUITIN LIGASES -: E3 (ubiquitin) ligases interact with both ubiquitin-E2 (ubiquitin-conjugating) enzymes and the target protein, transferring the ubiquitin from the E2 to the substrate. Members of the HECT family of E3 ubiquitin ligases are characterized by a C-terminal HECT domain. This catalytic domain forms an intermediate thioester bond with ubiquitin via a conserved Cys when transferring ubiquitin from the E2 to the target protein. (Adapted from FBrf0225009).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\ctrip for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.47

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Low-frequency RNA-Seq exon junction(s) not annotated.

Shares 5' UTR with upstream gene.

Gene model reviewed during 5.53

Sequence Ontology: Class of Gene

gene_with_edited_transcript

(Rodriguez et al., 2012, Graveley et al., 2011)

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

ctrip-RA

FBtr0301437

NM_141239

10589

3140

ctrip-RB

FBtr0303911

NM_001202241

10587

3140

ctrip-RC

FBtr0303912

NM_001202242

9366

2737

ctrip-RE

FBtr0303914

NM_001202244

9957

2930

ctrip-RF

FBtr0303915

NM_001202245

10759

3139

ctrip-RH

FBtr0303917

NM_001202247

9378

2737

ctrip-RI

FBtr0334902

NM_001202243

10136

2736

ctrip-RJ

FBtr0334903

NM_001202246

10831

2929

ctrip-RK

FBtr0344028

NM_001300232

10593

3111

ctrip-RL

FBtr0344029

NM_001300233

10631

2901

ctrip-RM

FBtr0344030

NM_001300234

9291

2708

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

ctrip-PA

FBpp0290652

336.6

3140

7.26

NP_649496

AAF52092

ctrip-PB

FBpp0292914

336.6

3140

7.26

NP_001189170

ADV37262

ctrip-PC

FBpp0292915

292.5

2737

6.72

NP_001189171

ADV37263

ctrip-PE

FBpp0292917

314.2

2930

6.99

NP_001189173

ADV37265

ctrip-PF

FBpp0292918

336.5

3139

7.26

NP_001189174

ADV37266

ctrip-PH

FBpp0292920

292.5

2737

6.72

NP_001189176

ADV37268

ctrip-PI

FBpp0306923

292.4

2736

6.72

NP_001189172

ADV37264

ctrip-PJ

FBpp0306924

314.1

2929

6.99

NP_001189175

ADV37267

ctrip-PK

FBpp0310477

333.7

3111

7.28

NP_001287161

AHN57160

ctrip-PL

FBpp0310478

311.3

2901

7.00

NP_001287162

AHN57161

ctrip-PM

FBpp0310479

289.6

2708

6.73

NP_001287163

AHN57162

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

3140 aa isoforms: ctrip-PA, ctrip-PB

2737 aa isoforms: ctrip-PC, ctrip-PH

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ctrip using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 13 -- 16

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

Reporter: P{GawB}1501

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

EH neurosecretory neuron

(Mirkovic et al., 2011)

third instar larval stage

prothoracic gland innervating neuron PG-LP

(Mirkovic et al., 2011)

larval Pdf neuron

(Mirkovic et al., 2011)

adult stage

adult Pdf neuron

(Mirkovic et al., 2011)

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\ctrip in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\ctrip

View exonic expression by tissue for Dmel\ctrip

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0260794

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0260794

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17735

Flygut - An atlas of the Drosophila adult midgut

FBgn0260794

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 12 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 9 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of ctrip

Transgenic constructs containing regulatory region of ctrip

Deletions and Duplications ( 2 )

Disrupted in

Df(3R)Exel6142

(Ryder, 2004.4.26)

Partially disrupted in

DF(3R)1501

(Lamaze et al., 2011)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal

lethal, with Scer\GAL4^pnr-MD237

ctrip^GD16533

lethal - all die before end of pupal stage, with Scer\GAL4^pnr-MD237

ctrip^GD8394

lethal - all die during P-stage, with Scer\GAL4^Mef2.PR

ctrip^GD16533

viable

ctrip^19F1

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

ctrip^GD9454

viable, with Scer\GAL4^Mef2.PR

ctrip^GD9454

viable, with Scer\GAL4^pnr-MD237

ctrip^GD9454

viable, with Scer\GAL4^tin.CΔ4

ctrip^GD9454

Other Phenotypes

Allele

circadian rhythm defective, with Scer\GAL4^P2.4.Pdf

circadian rhythm defective, with Scer\GAL4^P2.4.Pdf, ctrip^NIG.14656R

ctrip^NIG.17735R

circadian rhythm defective, with Scer\GAL4^P2.4.Pdf, ctrip^NIG.17735R

ctrip^NIG.14656R

circadian rhythm defective, with Scer\GAL4^tim.PE

circadian rhythm defective, with Scer\GAL4^tim.PE, ctrip^NIG.14656R

ctrip^NIG.17735R

circadian rhythm defective, with Scer\GAL4^tim.PE, ctrip^NIG.17735R

ctrip^NIG.14656R

locomotor rhythm defective, with Scer\GAL4^tim.PE

ctrip^miRNA.UAS

neuroanatomy defective | larval stage

ctrip^GD16533

some die during pupal stage, with Scer\GAL4^pnr-MD237

ctrip^GD8394

Phenotype manifest in

Allele

ganglion mother cell | larval stage

ctrip^GD16533

larval neuroblast | larval stage

ctrip^GD16533

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (38)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\TRIP12

10 of 15

Yes

3 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (35)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Trip12

9 of 15

Yes

2 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Rattus norvegicus (Norway rat) (29)

Rnor\Trip12

7 of 13

Yes

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Xenopus tropicalis (Western clawed frog) (26)

Xtro\trip12

10 of 12

Yes

Xtro\hectd1

2 of 12

Xtro\LOC101734904

2 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Danio rerio (Zebrafish) (40)

Drer\trip12

9 of 15

Yes

3 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Drer\si:ch211-281g13.4

1 of 15

Drer\si:ch211-281g13.5

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (10)

Cele\hecd-1

3 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

1 of 15

Arabidopsis thaliana (thale-cress) (2)

Atha\KAK

5 of 9

Yes

Atha\UPL4

4 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (5)

Scer\UFD4

8 of 15

Yes

1 of 15

1 of 15

1 of 15

1 of 15

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPAC12B10.01c

8 of 12

Yes

Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190093 )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila suzukii

Spotted wing Drosophila

Dsuz\DS10_00008599

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA30193

Drosophila persimilis

Dper\GL22220

Drosophila willistoni

Dwil\GK14424

Drosophila virilis

Dvir\GJ10115

Drosophila mojavensis

Dmoj\GI22511

Drosophila grimshawi

Dgri\GH17429

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500B5 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17011537

Glossina morsitans

Tsetse fly

Gmor\GMOY002668

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_12445

Mayetiola destructor

Hessian fly

Mdes\Mdes010120

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL017357

Anopheles darlingi

American malaria mosquito

Adar\ADAC009382

Anopheles gambiae

Malaria mosquito

Agam\AGAP001296

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ012812

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W00A8 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA007539

Danaus plexippus

Monarch butterfly

Dple\DPOGS204268-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL015203

Apis florea

Little honeybee

Aflo\2247287108

Apis mellifera

Western honey bee

Amel\LOC409382

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP25193

Bombus terrestris

Buff-tailed bumblebee

Bter\15216278

Linepithema humile

Argentine ant

Lhum\LH11940

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:001c97

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG006926

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_02693

Tribolium castaneum

Red flour beetle

Tcas\TC010408

Pediculus humanus

Human body louse

Phum\PHUM075960

Rhodnius prolixus

Kissing bug

Rpro\RPRC011284

Rhodnius prolixus

Kissing bug

Rpro\RPRC014638

Rhodnius prolixus

Kissing bug

Rpro\RPRC008389

Rhodnius prolixus

Kissing bug

Rpro\ctrip

Cimex lectularius

Bed bug

Clec\CLEC009803

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI009777

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_09932

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X00AI )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR005156

Stegodyphus mimosarum

African social velvet spider

Smim\KFM71329.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM64798.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur02g01880

Tetranychus urticae

Two-spotted spider mite

Turt\tetur02g01900

Tetranychus urticae

Two-spotted spider mite

Turt\tetur02g01940

Tetranychus urticae

Two-spotted spider mite

Turt\tetur02g01920

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_50916

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G00GQ )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-trip12

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_016715gn

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000022256

Ciona intestinalis

Vase tunicate

Cint\LOC100181389

Gallus gallus

Domestic chicken

Ggal\TRIP12

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (16)

Gene Symbol

Score

Source

Alignment

4 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

hyd

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

yki

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

TRIP12; thyroid hormone receptor interactor 12

model of Clark-Baraitser syndrome

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

TRIP12; thyroid hormone receptor interactor 12

10 of 15

604506

CLARK-BARAITSER SYNDROME; CLABARS

Clark-Baraitser syndrome

HECTD1; HECT domain E3 ubiquitin protein ligase 1

3 of 15

618649

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

65812

DroID - A comprehensive database of gene and protein interactions.

FBgn0260794

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

40596

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Ubiquitin mediated proteolysis

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Antigen processing: Ubiquitination & Proteasome degradation

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-47.1

Cytogenetic map

82D5-82D6

Sequence location

3R:4,786,284..4,812,096 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

82D5-82D6

Limits computationally determined from genome sequence between P{PZ}l(3)02733⁰²⁷³³ and P{EP}EP974

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-47.1

(FlyBase, 2016)

3-44.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (18)

Bloomington

21989

w¹¹¹⁸; P{EPg}ctrip^HP35916

44481

y¹ v¹; P{TRiP.HMC02371}attP40

31840

w¹¹¹⁸; P{EP}ctrip^G19129/TM6C, Sb¹

33435

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00322}attP2

56575

y¹ w^*; Mi{MIC}Hus1-like^MI11259 ctrip^MI11259

Kyoto

104350

w^*; P{GawB}Hus1-like^NP3036

VDRC

v50190

P{GD9454}v50190

v108546

P{KK100515}VIE-260B

v18304

w¹¹¹⁸ P{GD8394}v18304

v48052

w¹¹¹⁸; P{GD16533}v48052

v48117

w¹¹¹⁸; P{GD16533}v48117

v50189

w¹¹¹⁸; P{GD9454}v50189/TM3

More stocks available...

Genomic Clones (20)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (97)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0260794

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0260794

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40596

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: CG17735 CG14656

(FlyBase Genome Annotators, 2008)

Additional comments

Annotations CG17735 and CG14656 merged as CG42574 in release 5.16 of the genome annotation.

(FlyBase Genome Annotators, 2008)

Other Comments

Origin and Etymology

Discoverer

Etymology

Source for identity of: ctrip CG42574

(Lamaze et al., 2011)

Identification

External Crossreferences and Linkouts ( 70 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

40596

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0260794

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0260794

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17735

Flygut - An atlas of the Drosophila adult midgut

FBgn0260794

FlyMine - An integrated database for Drosophila genomics

FBgn0260794

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

40596

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC010408

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG42574

modMine - A data warehouse for the modENCODE project

FBgn0260794

Linkouts

BioGRID - A database of protein and genetic interactions.

65812

DroID - A comprehensive database of gene and protein interactions.

FBgn0260794

DRSC - Results frm RNAi screens

FBgn0260794

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

FBgn0260794

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

40596

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Ubiquitin mediated proteolysis

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Antigen processing: Ubiquitination & Proteasome degradation

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

CG14656

(Ashwal-Fluss et al., 2014, Yano et al., 2012, Buszczak et al., 2007, Zhang et al., 2007)

CG17735

(Lou et al., 2017, Christis and Munro, 2012, Du et al., 2011, Lamaze et al., 2011, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Peschel et al., 2009, Hoopfer et al., 2008, Sathyanarayanan et al., 2008)

CG42574

(Çiçek et al., 2016, Hosono et al., 2015, Sen et al., 2013, Lamaze et al., 2011, Ni et al., 2010.12.1, FlyBase Genome Annotators, 2008)

CTRIP

(Tataroglu and Emery, 2015)

CTRIP/TRIP12

(Greenblatt and Spradling, 2018)

Ctrip

(Pamudurti et al., 2020)

ctrip

(Rajpurohit et al., 2018, Ketosugbo et al., 2017, Stessman et al., 2017, Gene Disruption Project members, 2016-, Aradska et al., 2015, Gene Disruption Project members, 2015-, Rodriguez et al., 2012, Lamaze et al., 2011)

Name Synonyms

CG14656

CG17735

circadian trip

(Lamaze et al., 2011)

Secondary FlyBase IDs

FBgn0037277
FBgn0037278

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (66)

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