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Gene Dmel\p120ctn

General Information
Symbol	Dmel\p120ctn	Species	D. melanogaster
Name	Adherens junction protein p120	Annotation symbol	CG17484
Feature type	protein_coding_gene	FlyBase ID	FBgn0260799
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	p120, p120ctn, dP120ctn, Dp120ctn
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	41B1-41B1	Sequence location	2R:482,798..496,995 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Adherens junction protein p120 is referred to in FlyBase by the symbol Dmel\p120ctn (CG17484, FBgn0260799). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding. There is experimental evidence that it is involved in the biological process: adherens junction maintenance; cell adhesion; compound eye morphogenesis. 15 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; stage 14 embryo; inter-ommatidial cell; embryonic leading edge cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo; Armadillo-like helical; Armadillo-type fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval hindgut, larval fat body, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult spermathecae, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635501_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of p120ctn. Gene sequence location is 2R:482798..496995.
External Summaries
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN40704 BKN33572 HFA07753
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 41B1-41B1
Experimentally Determined Cytological Location
Cytogenetic map Notes References 41C-41C   (determined by in situ hybridisation)   (Myster et al., 2004) 41C1-41C6   h46   (Drosophila Heterochromatin Genome Project, 2004) 41C-41C   (determined by in situ hybridisation)   (Myster et al., 2003) 41A-41C     (Cavallo, 2000.1.3)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\p120ctn for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) p120ctn-RA FBtr0111114  NM_001042979   2678   781 p120ctn-RB FBtr0111113  NM_001042978   2958   767
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein p120ctn-PA   FBpp0110406   86.8   781   6.90     NP_001036444   EAA45985 p120ctn-PB   FBpp0110405   85.3   767   6.76     NP_001036443   ABI31015
Additional Polypeptide Data & Comments
Reported size (kDa)	781 (aa); 88 (kD observed); 87 (kD predicted) (Myster et al., 2003)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Armadillo (IPR000225) Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201250   AA201830   AA202435   AA202534   AA246780   AA263534   AA390418   AA392872   AA538850   AA539155   AA539735   AA540781   AA695465   AA696279   AA950212   AABU01002769 EAA45985   AE013599 ABI31015   AF220496 AAF33245   AI514636   AW941533   AY069321 AAL39466   AY075408   BI164206   BI164839   BI164858   BI164918   BI165246   BI166151   BI169636   BI170123   BI170423   BI170990   BI171931   BI212927   BI214427   BI216320   BI227471   BI228045   BI233105   BI233115   BI236483   BI236658   BI236665   BI241636   BI356909   BI357298   BI357421   BI367428   BI367848   BI368718   BI368962   BI369931   BI370955   BI374177   BI374326   BI375120   BI482403   BI483720   BI484874   BI578826   BP549147   BP549148   BP549204   BP549205   BP553220   BT044597   CA805717   CA805928   CK131583   CO152754   CO154184   CO179209   CO179343   CO179365   CO184448   CO185391   CO185521   CO187838   CO188930   CO195696   CO196406   CO262947   CO262952   CO270965   CO271375   CO276922   CO277690   CO278345   CO278700   CO291427   CO291431   CO291897   CO291899   CO291901   CO291903   CO291905   CO291906   CO291907   CO291908   CO291909   CO291910   CO291911   CO291912   CO293167   CO293170   CO293222   CO293458   CO297434   CO299352   CO299935   CO300382   CO302315   CO303148   CO303191   CO305515   CO309323   CO309740   CO311205   CO311208   CO313753   CO314671   CO320583   CO320992   CO321011   CO321549   CO323225   CO326879   CO327326   CO327817   CO328397   CO330770   CO330860   CO331514   CO332127   CO332347   CO334075   CO337754   CO340157   CO340181   AE013599 EAA45985   EC057294   EC059194   EC061580   EC062969   EC063716   EC068255   EC069862   EC069867   EC070395   EC077385   EC078889   EC079686   EC082056   EC087342   EC089125   EC089168   EC090385   EC196512   EC199711   EC200864   EC205133   EC205457   EC206819   EC208129   EC212617   EC213314   EC214317   EC217088   EC217089   EC218719   EC220007   EC220217   EC221541   EC225203   EC228157   EC228860   EC230332   EC231300   EC231696   EC232207   EC233187   EC234396   EC235705   EC239474   EC239736   EC242301   EC242606   EC243461   EC244483   EC247105   EC247692   EC255419   EC255717   EC255807   EC260298   EC265383   EC265554   EC267037   EV578620   EV579139   GH945027   GH946386   GH947930   GH948243   GH950808   GH950824   GH951515   GH959001   GH963540   GH967972   GH968955   GH970082   GH970258   GH970930   GH976050   GH977299   GH980578   GH980852   GH982679   GH983894
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7PLI0 Q8T0H3 Q9NHP1 Q0E9Q5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage   posterior embryonic/larval midgut   (Myster et al., 2003) presumptive embryonic/larval central nervous system   (Myster et al., 2003) embryonic foregut   (Myster et al., 2003) anterior embryonic/larval midgut   (Myster et al., 2003) embryonic hindgut   (Myster et al., 2003) organism | ubiquitous   (Myster et al., 2003) midgut constriction   (Myster et al., 2003)
Additional Descriptive Data
	p120ctn transcripts are expressed in all cells during embryogenesis. Elevated levels are observed in several tissues, many of which are undergoing morphogenetic movements including the invaginating posterior midgut, CNS, migrating anterior and posterior midguts, foregut, hindgut, and cells in the midgut constriction. (Myster et al., 2003)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
immunolocalization Stage Tissue/Position (including subcellular localization) Reference embryonic stage   presumptive embryonic/larval tracheal system   (Myster et al., 2003) presumptive embryonic/larval central nervous system | restricted   (Myster et al., 2003) embryonic sensory system   (Myster et al., 2003) presumptive embryonic/larval peripheral nervous system | restricted   (Myster et al., 2003) embryonic stage & larval stage   neuron   • axon (Myster et al., 2003) embryonic stage 4 -- 9     • spindle (Myster et al., 2003)   • centrosome (Myster et al., 2003) embryonic stage 10 -- 17   embryonic/larval midgut primordium   • cell-cell adherens junction (Myster et al., 2003) embryonic epidermis   • cell-cell adherens junction (Myster et al., 2003) larval stage   ganglion mother cell   (Myster et al., 2003) embryonic/larval brain | restricted   (Myster et al., 2003) morphogenetic furrow | anterior to   (Myster et al., 2003) neuroblast   (Myster et al., 2003) eye disc   (Myster et al., 2003) morphogenetic furrow   (Myster et al., 2003) oogenesis   border follicle cell   • cell-cell adherens junction (Myster et al., 2003) germline cell   • cell-cell adherens junction (Myster et al., 2003) follicle cell   • cell-cell adherens junction (Myster et al., 2003)
Additional Descriptive Data
	In ovaries, p120ctn protein accumulates in the adherens junctions of epithelial follicle cells, at junctions between migrating border cells, and weakly in junctions between germ cells. In embryos, p120ctn protein accumulates at cell-cell adherens junctions in the epidermis and gut. The protein is present throughout embryogenesis, though the levels are lower in early embryonic stages than those of other core adherens junctions proteins such as arm protein and shg protein. p120ctn protein also accumulates in a variety of other tissues as observed in some cases by GFP staining. These include trachea, axons of the CNS, and sensory structures of the PNS. In eye imaginal discs, p120ctn protein localizes at cell-cell boundaries anterior to the morphogenetic furrow and at elevated levels where differentiating cells abut one another. In larval brains, @p120ctn localizes to cell-cell boundaries between nuroblasts, to GMCs, and to axons emerging from neuroblast progeny. (Myster et al., 2003)
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0260799    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0260799 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0260799 expression level Developmental Stage   Expression Level embryo 00-02hr    3676 embryo 02-04hr    5272 embryo 04-06hr    4956 embryo 06-08hr    3756 embryo 08-10hr    5551 embryo 10-12hr    5871 embryo 12-14hr    6715 embryo 14-16hr    1802 embryo 16-18hr    3077 embryo 18-20hr    1533 embryo 20-22hr    2719 embryo 22-24hr    3993 larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6    1639 larva L3 puffstage 7-9    3213 white prepupae new    3543 white prepupae 12hr    3407 white prepupae 24hr    3381 pupae 2d postWPP    3036 pupae 3d postWPP    2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day    2603 adult female 30day    2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3676) embryo 02-04hr  (5272) embryo 04-06hr  (4956) embryo 06-08hr  (3756) embryo 08-10hr  (5551) embryo 10-12hr  (5871) embryo 12-14hr  (6715) embryo 14-16hr  (1802) embryo 16-18hr  (3077) embryo 18-20hr  (1533) embryo 20-22hr  (2719) embryo 22-24hr  (3993) larva L1  (938) larva L2  (1079) larva L3 12hr old  (656) larva L3 puffstage 1-2  (922) larva L3 puffstage 3-6  (1639) larva L3 puffstage 7-9  (3213) white prepupae new  (3543) white prepupae 12hr  (3407) white prepupae 24hr  (3381) pupae 2d postWPP  (3036) pupae 3d postWPP  (2034) pupae 4d postWPP  (677) adult male 01day  (1191) adult male 05day  (813) adult male 30day  (580) adult female 01day  (786) adult female 05day  (2603) adult female 30day  (2013) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3676) embryo 02-04hr  (5272) embryo 04-06hr  (4956) embryo 06-08hr  (3756) embryo 08-10hr  (5551) embryo 10-12hr  (5871) embryo 12-14hr  (6715) embryo 14-16hr  (1802) embryo 16-18hr  (3077) embryo 18-20hr  (1533) embryo 20-22hr  (2719) embryo 22-24hr  (3993) larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6  (1639) larva L3 puffstage 7-9  (3213) white prepupae new  (3543) white prepupae 12hr  (3407) white prepupae 24hr  (3381) pupae 2d postWPP  (3036) pupae 3d postWPP  (2034) pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day  (2603) adult female 30day  (2013) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3676 embryo 02-04hr    5272 embryo 04-06hr    4956 embryo 06-08hr    3756 embryo 08-10hr    5551 embryo 10-12hr    5871 embryo 12-14hr    6715 embryo 14-16hr    1802 embryo 16-18hr    3077 embryo 18-20hr    1533 embryo 20-22hr    2719 embryo 22-24hr    3993 larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6    1639 larva L3 puffstage 7-9    3213 white prepupae new    3543 white prepupae 12hr    3407 white prepupae 24hr    3381 pupae 2d postWPP    3036 pupae 3d postWPP    2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day    2603 adult female 30day    2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3676 embryo 02-04hr    5272 embryo 04-06hr    4956 embryo 06-08hr    3756 embryo 08-10hr    5551 embryo 10-12hr    5871 embryo 12-14hr    6715 embryo 14-16hr    1802 embryo 16-18hr    3077 embryo 18-20hr    1533 embryo 20-22hr    2719 embryo 22-24hr    3993 larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6    1639 larva L3 puffstage 7-9    3213 white prepupae new    3543 white prepupae 12hr    3407 white prepupae 24hr    3381 pupae 2d postWPP    3036 pupae 3d postWPP    2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day    2603 adult female 30day    2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0260799 expression level Developmental Stage   Expression Level embryo 00-02hr    3676 embryo 02-04hr    5272 embryo 04-06hr    4956 embryo 06-08hr    3756 embryo 08-10hr    5551 embryo 10-12hr    5871 embryo 12-14hr    6715 embryo 14-16hr    1802 embryo 16-18hr    3077 embryo 18-20hr    1533 embryo 20-22hr    2719 embryo 22-24hr    3993 larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6    1639 larva L3 puffstage 7-9    3213 white prepupae new    3543 white prepupae 12hr    3407 white prepupae 24hr    3381 pupae 2d postWPP    3036 pupae 3d postWPP    2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day    2603 adult female 30day    2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3676) embryo 02-04hr  (5272) embryo 04-06hr  (4956) embryo 06-08hr  (3756) embryo 08-10hr  (5551) embryo 10-12hr  (5871) embryo 12-14hr  (6715) embryo 14-16hr  (1802) embryo 16-18hr  (3077) embryo 18-20hr  (1533) embryo 20-22hr  (2719) embryo 22-24hr  (3993) larva L1  (938) larva L2  (1079) larva L3 12hr old  (656) larva L3 puffstage 1-2  (922) larva L3 puffstage 3-6  (1639) larva L3 puffstage 7-9  (3213) white prepupae new  (3543) white prepupae 12hr  (3407) white prepupae 24hr  (3381) pupae 2d postWPP  (3036) pupae 3d postWPP  (2034) pupae 4d postWPP  (677) adult male 01day  (1191) adult male 05day  (813) adult male 30day  (580) adult female 01day  (786) adult female 05day  (2603) adult female 30day  (2013) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3676) embryo 02-04hr  (5272) embryo 04-06hr  (4956) embryo 06-08hr  (3756) embryo 08-10hr  (5551) embryo 10-12hr  (5871) embryo 12-14hr  (6715) embryo 14-16hr  1802 embryo 16-18hr  (3077) embryo 18-20hr  1533 embryo 20-22hr  (2719) embryo 22-24hr  (3993) larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6  1639 larva L3 puffstage 7-9  (3213) white prepupae new  (3543) white prepupae 12hr  (3407) white prepupae 24hr  (3381) pupae 2d postWPP  (3036) pupae 3d postWPP  2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day  (2603) adult female 30day  2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3676 embryo 02-04hr    5272 embryo 04-06hr    4956 embryo 06-08hr    3756 embryo 08-10hr    5551 embryo 10-12hr    5871 embryo 12-14hr    6715 embryo 14-16hr    1802 embryo 16-18hr    3077 embryo 18-20hr    1533 embryo 20-22hr    2719 embryo 22-24hr    3993 larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6    1639 larva L3 puffstage 7-9    3213 white prepupae new    3543 white prepupae 12hr    3407 white prepupae 24hr    3381 pupae 2d postWPP    3036 pupae 3d postWPP    2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day    2603 adult female 30day    2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3676 embryo 02-04hr    5272 embryo 04-06hr    4956 embryo 06-08hr    3756 embryo 08-10hr    5551 embryo 10-12hr    5871 embryo 12-14hr    6715 embryo 14-16hr    1802 embryo 16-18hr    3077 embryo 18-20hr    1533 embryo 20-22hr    2719 embryo 22-24hr    3993 larva L1    938 larva L2    1079 larva L3 12hr old    656 larva L3 puffstage 1-2    922 larva L3 puffstage 3-6    1639 larva L3 puffstage 7-9    3213 white prepupae new    3543 white prepupae 12hr    3407 white prepupae 24hr    3381 pupae 2d postWPP    3036 pupae 3d postWPP    2034 pupae 4d postWPP    677 adult male 01day    1191 adult male 05day    813 adult male 30day    580 adult female 01day    786 adult female 05day    2603 adult female 30day    2013 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0260799    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0260799 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval hindgut, larval fat body, larval trachea, adult ovary. Expression at moderate levels in the following post-embryonic organs or tissues: adult crop, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult spermathecae, adult male reproductive system, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0260799 expression level Tissue   Expression Level Larval Central Nervous System    1104.6 Larval Midgut    258.6 Larval Hindgut    599.5 Larval Malpighian Tubules    407.2 Larval Fat Body    697.2 Larval Salivary Gland    308.8 Larval Trachea    621.25 Larval Carcass    396.55 Adult Head    781 Adult Eye    1675.05 Adult Brain    1059.6 Adult Thoracic-Abdominal Ganglion    1209.8 Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary    794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1104.6) Larval Midgut    258.6 Larval Hindgut  (599.5) Larval Malpighian Tubules    407.2 Larval Fat Body  (697.2) Larval Salivary Gland    308.8 Larval Trachea  (621.25) Larval Carcass    396.55 Adult Head  (781) Adult Eye  (1675.05) Adult Brain  (1059.6) Adult Thoracic-Abdominal Ganglion  (1209.8) Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary  (794.3) Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  (1104.6) Larval Midgut    258.6 Larval Hindgut    599.5 Larval Malpighian Tubules    407.2 Larval Fat Body    697.2 Larval Salivary Gland    308.8 Larval Trachea    621.25 Larval Carcass    396.55 Adult Head    781 Adult Eye  (1675.05) Adult Brain  1059.6 Adult Thoracic-Abdominal Ganglion  (1209.8) Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary    794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1104.6 Larval Midgut    258.6 Larval Hindgut    599.5 Larval Malpighian Tubules    407.2 Larval Fat Body    697.2 Larval Salivary Gland    308.8 Larval Trachea    621.25 Larval Carcass    396.55 Adult Head    781 Adult Eye    1675.05 Adult Brain    1059.6 Adult Thoracic-Abdominal Ganglion    1209.8 Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary    794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0260799 expression level Tissue   Expression Level Larval Central Nervous System    1104.6 Larval Midgut    258.6 Larval Hindgut    599.5 Larval Malpighian Tubules    407.2 Larval Fat Body    697.2 Larval Salivary Gland    308.8 Larval Trachea    621.25 Larval Carcass    396.55 Adult Head    781 Adult Eye    1675.05 Adult Brain    1059.6 Adult Thoracic-Abdominal Ganglion    1209.8 Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary    794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (1104.6) Larval Midgut    258.6 Larval Hindgut  599.5 Larval Malpighian Tubules    407.2 Larval Fat Body  697.2 Larval Salivary Gland    308.8 Larval Trachea  621.25 Larval Carcass    396.55 Adult Head  781 Adult Eye  (1675.05) Adult Brain  (1059.6) Adult Thoracic-Abdominal Ganglion  (1209.8) Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary  794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System  1104.6 Larval Midgut    258.6 Larval Hindgut    599.5 Larval Malpighian Tubules    407.2 Larval Fat Body    697.2 Larval Salivary Gland    308.8 Larval Trachea    621.25 Larval Carcass    396.55 Adult Head    781 Adult Eye  1675.05 Adult Brain  1059.6 Adult Thoracic-Abdominal Ganglion  1209.8 Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary    794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1104.6 Larval Midgut    258.6 Larval Hindgut    599.5 Larval Malpighian Tubules    407.2 Larval Fat Body    697.2 Larval Salivary Gland    308.8 Larval Trachea    621.25 Larval Carcass    396.55 Adult Head    781 Adult Eye    1675.05 Adult Brain    1059.6 Adult Thoracic-Abdominal Ganglion    1209.8 Adult Crop    440.8 Adult Midgut    212.8 Adult Hindgut    367.4 Adult Malpighian Tubules    153.5 Adult Fat Body    259.4 Adult Salivary Gland    147.3 Adult Heart    333.425 Adult VirginFemale Spermatheca    415.3 Adult InseminatedFemale Spermatheca    436.8 Adult Ovary    794.3 Adult Testis    165.2 Adult Male Accessory Gland    153.5 Adult Carcass    220.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    781   NA  Eye    1675.05   NA  Brain    1059.6   1104.6  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1209.8   NA  Crop    440.8   258.6  Midgut    212.8   599.5  Hindgut    367.4   407.2  Malpighian Tubules    153.5   697.2  Fat Body    259.4   308.8  Salivary Gland    147.3   NA  Heart    333.425   621.25  Trachea    NA   NA  VirginFemale Spermatheca    415.3   NA  InseminatedFemale Spermatheca    436.8   NA  Ovary    794.3   NA  Testis    165.2   NA  Male Accessory Gland    153.5   396.55  Carcass    220.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0260799
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | partially, with Scer\GAL4Act5C.PI p120ctnScer\UAS.P\T.cMa viable p120ctn308 p120ctndsRNA.cFa Sterility Allele fertile p120ctn308 Other Phenotypes Allele cell shape defective p120ctn308 developmental rate defective p120ctn308 neuroanatomy defective p120ctn308 Phenotype manifest in Allele dorsal closure embryo p120ctn308 embryonic leading edge cell p120ctn308 inter-ommatidial cell p120ctn308 stage 14 embryo, with p120ctna.cMa p120ctncMa stage 14 embryo, with p120ctncMa p120ctna.cMa tertiary pigment cell | supernumerary p120ctn308
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of p120ctn Class Mutagen Stocks Known lesion p120ctn308 amorphic allele - genetic evidence, loss of function allele P-element activity 1 Yes p120ctnMB06056 1 --
Alleles Carried on Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Allele of p120ctn Class Mutagen Stocks Known lesion p120ctnUbi-p63E.T:Avic\GFP in vitro construct - coding region fusion in vitro construct - regulatory fusion 2 Yes p120ctnKK113572 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes p120ctnScer\UAS.T:Avic\GFP in vitro construct - coding region fusion in vitro construct - regulatory fusion 1 Yes p120ctn2200.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes p120ctn700.Scer\UAS.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes p120ctna.cMa in vitro construct - RNAi 0 Yes p120ctncMa in vitro construct - RNAi 0 Yes p120ctndsRNA.cFa in vitro construct - RNAi 0 Yes p120ctndsRNA.Scer\UAS in vitro construct - regulatory fusion 0 Yes p120ctnScer\UAS.cFa 0 -- p120ctnScer\UAS.P\T.cMa in vitro construct - regulatory fusion 0 Yes p120ctnScer\UAS.T:Hsap\MYC in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes p120ctnUbi-p63E.T:Hsap\MYC in vitro construct - coding region fusion in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)244 (Larson et al., 2008, Myster et al., 2004, Myster et al., 2004) Df(2R)247 (Myster et al., 2004, Myster et al., 2004) Df(2R)M41A2 (Myster et al., 2004, Myster et al., 2004, Coulthard et al., 2010) Df(2R)M41A4 (Myster et al., 2004) Df(2R)M41A8 (Myster et al., 2004, Myster et al., 2004) Df(2R)M41A10 (Myster et al., 2004, Myster et al., 2004) Df(2R)NC13 (Myster et al., 2004) Df(2R)NC50 (Myster et al., 2004) Df(2R)NC68 (Myster et al., 2004) Df(2R)NC125 (Myster et al., 2004) Df(2R)NC167 (Myster et al., 2004) Df(2R)NC191 (Myster et al., 2004) Df(2R)NC202 (Myster et al., 2004) Df(2R)NC218 (Myster et al., 2004) Df(2R)NC228 (Myster et al., 2004) Df(2R)Nipped-D (Myster et al., 2004, Myster et al., 2004)
Not disrupted in	Df(2R)34-2 (Coulthard et al., 2010) Df(2R)Dark2 (Myster et al., 2004) Df(2R)nap1 (Myster et al., 2004) Df(2R)NC32 (Myster et al., 2004) Df(2R)NC73 (Myster et al., 2004) Df(2R)NC98 (Myster et al., 2004) Df(2R)NC168 (Myster et al., 2004) Df(2R)NC195 (Myster et al., 2004) Df(2R)NC207 (Myster et al., 2004) Df(2R)NC219 (Myster et al., 2004) Df(2R)NC1198 (Myster et al., 2004)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK113572} NA P{UAS-p120ctn.700.dsRNA} NA P{UAS-p120ctn.2200.dsRNA} NA P{UAS-p120ctn.F} NA P{UAS-p120ctn.HA} NA P{UAS-p120ctn.myc} NA P{UAS-p120ctn.ΔC.GFP} NA P{UASp-p120ctn.M} NA characterization construct P{Ubi-p63E-p120ctn.myc} NA P{Ubi-p63E-p120ctn.ΔC.GFP} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{SUPor-P}KG01086 NA insertion of enhancer trap binary system Mi{ET1}p120ctnMB06056 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 6 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
adherens junction maintenance inferred from mutant phenotype (Larson et al., 2008) cell adhesion inferred from genetic interaction with arm AND inferred from genetic interaction with shg (Myster et al., 2003) compound eye morphogenesis inferred from genetic interaction with Rho1 (Larson et al., 2008) inferred from genetic interaction with shg (Larson et al., 2008) inferred from mutant phenotype (Larson et al., 2008)
Cellular Component
CV term Evidence References
adherens junction inferred from direct assay AND inferred from physical interaction with arm AND inferred from physical interaction with shg (Myster et al., 2003) centrosome inferred from direct assay (Myster et al., 2003) cytoplasm inferred from direct assay (Myster et al., 2003)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011989, InterPro:IPR016024 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
adherens junction inferred from sequence or structural similarity (Cavallo et al., 1996)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions p120ctn allele Gene References p120ctn308 arm (Myster et al., 2003) shg (Myster et al., 2003) p120ctnScer\UAS.P\T.cMa Rho1 (Magie et al., 2002)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 78268 DroID - A comprehensive database of gene and protein interactions. • FBgn0260799 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 3355143
Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL005461-PA Aedes aegypti (mosquito) XP_391862.3 Apis mellifera (honey bee) XP_001943784.1 Acyrthosiphon pisum (pea aphid) 244427 Branchiostoma floridae (lancelet) BGIBMGA005731-PA Bombyx mori (silk worm) ENSBTAP00000041323 Bos taurus (bovine) ENSCAFP00000014680 Canis familiaris (dog) CAGL0M03355g Candida glabrata (haploid yeast) ENSCINP00000018587 Ciona intestinalis (sea squirt) CPIJ005144 Culex pipens (mosquito) ENSCPOP00000016210 Cavia porcellus (guinea pig) RP36557 Caenorhabditis remanei (nematode) ENSCSAVP00000018915 Ciona savignyi (sedentary tunicate) 327969 Daphnia pulex (daphnia) ENSDARP00000081704 Danio rerio (zebra fish) ENSECAP00000015621 Equus caballus (horse) ENSGACP00000017200 Gymnopilus aculeatus (mushroom) ENSGALP00000036312 Gallus gallus (chicken) 191187 Hypsipyla robusta (cedar shoot borer) ENSP00000263207 Homo sapiens (human) ISCW015271-PA Ixodes scapularis (deer tick) KLLA0A11286g Kluyveromyces lactis (yeast) 114795 Lottia gigantea (owl limpet) ENSMODP00000003021 Monodelphis domestica (gray opossum) ENSMMUP00000022560 Macaca mulatta (rhesus monkey) ENSMUSP00000111281 Mus musculus (house mouse) 50978 Nematostella vectensis (starlet anemone) XP_001603430.1 Nasonia vitripennis (wasp) ENSOANP00000018378 Ornithorynchus anatinus (platypus) ENSORLP00000002327 Oryzias latipes (japanese killifish) PHUM004493-PA Pediculus humanus (human body louse) ENSPPYP00000012927 Pongo pygmaeus (orangutan) ENSPTRP00000024233 Pan troglodytes (chimpanzee) ENSRNOP00000002585 Rattus norvegicus (norway rat) Smp_042340 Schistosoma mansoni (trematode parasite) 13097 Trichoplax adhaerens (metazoa) XP_968711.2 Tribolium castaneum (red flour beetle) ENSTNIP00000009132 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000004883 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000013844 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10667 LH22593 ISCW015271 FBgn0223368 JGI_V11_327969 FBgn0141607 FBgn0129183 CPIJ005144 BGIBMGA005731 ACYPI008244 GB30504 GB30128 GB19511 AGAP011273 AAEL005461 PB24624 PHUM236350 GLEAN_01464
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	6664 p120ctn308 25237 w1118; Mi{ET1}p120ctnMB06056 7192 y1 w*; P{UAS-p120ctn.ΔC.GFP}S2 7191 y1 w*; P{Ubi-p63E-p120ctn.ΔC.GFP}L2/CyO 7190 y1 w*; P{Ubi-p63E-p120ctn.ΔC.GFP}M3/TM3, Sb1
VDRC	v103063 P{KK113572}VIE-260B
Genomic Clones ( 1 )
	BACR15A11 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 204 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD03740 LD33274 RE55335
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM02869 GM05437 LD02245 LD02621 LD04185 LD05720 LD06635 LD09338 LD12011 LD17247 LD18054 LD18474 LD20593 LD30173 LD46176 LP11508 RE03834 RE04589 RE04616 RE04688 RE05092 RE06183 RE10873 RE11481 RE11864 RE12631 RE13832 RE18196 RE20232 RE23414 RE24528 RE25461 RE29384 RE29396 RE32542 RE32744 RE32753 RE38754 RE43192 RE43733 RE43906 RE53191 RE53705 RE54735 RE55028 RE56273 RE57743 RE61704 RE61882 RE62855 RE65090 RE66644 RE68054 RE72756
Other clones	1077 17879 18102 35865 47406 53992 61062 66427 72982 73031 73547 74261 81754 83043 84411 100963 119319 146171 155832 156638 191551 192687 193273 214277.46 214321.9 214385.43 214505.34 273075 274719 275399 283444 473620 523229 569602 CK01.6A.C6 CK01.14A.C6 CK01.52B.H11 CK01.74D.E6 CK01.75C.E6 CK01.75C.F11 CK01.96B.D8 CK01.103C.C5 CK01.103C.E5 CK01.106C.E4 CK01.114A.C6 CK01.115B.A10 CK01.123B.C8 CK01.123D.E12 CK01.132D.C3 CK01.168B.F5 Dmel_dig_001975_0706_0427 Dmel_dig_018181_0612_0728 EC28108 EC40792 EK004126 EK009008 EK009907 EK033935 EK042430 EK058751 EK059151 EK059222 EK079303 EK079311 EK086911 EK086919 EK101210 EK103223 EK122413 EK125829 EK129831 EK131162 EK175140 EK176939 EK178058 EK183902 EK185913 EK190002 EK198701 EK198705 EK198709 EK198713 EK198717 EK198721 EK198725 EK198729 EK198733 EK198737 EK198741 EK198745 EK201956 EK201963 EK202162 EK202947 EK216957 EK217341 EK219019 EK223740 EK223743 EK234007 EK237412 EK240307 EK240506 EK248851 EK286358 EK290110 EK290131 EK296139 EK296325 EK300026 EK302553 EK303223 EK308822 EN00349 EN03655 EN15232 EP04907 EP06801 EP08101 EP09133 EP10122 EP10148 ESG0119b.B21_F06 ESG0120b.B21_E03 FGM003H09 FGM004C03 FGM223C06 RP004016943 RP004163661 RP004165331 RP004168132 RP004201095 RP004203553 RP004204982 RP004218238 RP004220449 RP004235678 RP004237641 RP004239470 RP004297280 RP004329085 RP004420414 RP004429383 RP004432045 RP004448126 RP004460728 RP004513781
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0260799 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3355143
Antibody Information
	polyclonal (Myster et al., 2003)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: p120ctn CG17484 (Peifer, 2000.4.6) Source for merge of: p120ctn δ-catenin (FlyBase, 1992-)
Additional comments
Other Comments
	Not an essential gene. (Myster et al., 2004) Df(2R)244 deletion mutants for this gene are viable and fertile. (Myster et al., 2004) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) p120ctn interacts with the juxtamembrane region of shg. Overall orientation not stated: Stlk+ p120ctn+ P{SUPor-P}KG01086? CG17486+ (Myster et al., 2003) p120ctn seems to encode an important positive modulator of cell adhesion though not itself an essential core component of the adherens junction. (Myster et al., 2003) A single member of the p120/δ-catenin family (p120ctn) is encoded in the D.melanogaster genome. (Pacquelet et al., 2003) The interaction of shg with p120ctn is not required for shg function in vivo. (Pacquelet et al., 2003) Identified by PCR based on homology to the vertebrate homologs. (Cavallo et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001042978 NM_001042979 RefSeq (Proteins) • NP_001036443 NP_001036444 DDBJ / EMBL / GenBank • AA201830 AABU01002769 AAF33245 AAL39466 ABI31015 AF220496 AW941533 AY069321 EAA45985 Entrez Gene - A searchable database of RefSeq genes. • 3355143 UniProtKB/TrEMBL • Q0E9Q5 Q7PLI0 Q8T0H3 Q9NHP1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Armadillo (IPR000225) Armadillo-like helical (IPR011989) Armadillo-type fold (IPR016024)
Linkouts
	BioGRID - A database of protein and genetic interactions • 78268 DroID - A comprehensive database of gene and protein interactions. • FBgn0260799 DRSC - Results from RNAi screens. • FBgn0260799 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0260799 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0260799 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 3355143 InParanoid A subset of ortholog calls from InParanoid. • AAEL005461-PA Aedes aegypti (mosquito) XP_391862.3 Apis mellifera (honey bee) XP_001943784.1 Acyrthosiphon pisum (pea aphid) 244427 Branchiostoma floridae (lancelet) BGIBMGA005731-PA Bombyx mori (silk worm) ENSBTAP00000041323 Bos taurus (bovine) ENSCAFP00000014680 Canis familiaris (dog) CAGL0M03355g Candida glabrata (haploid yeast) ENSCINP00000018587 Ciona intestinalis (sea squirt) CPIJ005144 Culex pipens (mosquito) ENSCPOP00000016210 Cavia porcellus (guinea pig) RP36557 Caenorhabditis remanei (nematode) ENSCSAVP00000018915 Ciona savignyi (sedentary tunicate) 327969 Daphnia pulex (daphnia) ENSDARP00000081704 Danio rerio (zebra fish) ENSECAP00000015621 Equus caballus (horse) ENSGACP00000017200 Gymnopilus aculeatus (mushroom) ENSGALP00000036312 Gallus gallus (chicken) 191187 Hypsipyla robusta (cedar shoot borer) ENSP00000263207 Homo sapiens (human) ISCW015271-PA Ixodes scapularis (deer tick) KLLA0A11286g Kluyveromyces lactis (yeast) 114795 Lottia gigantea (owl limpet) ENSMODP00000003021 Monodelphis domestica (gray opossum) ENSMMUP00000022560 Macaca mulatta (rhesus monkey) ENSMUSP00000111281 Mus musculus (house mouse) 50978 Nematostella vectensis (starlet anemone) XP_001603430.1 Nasonia vitripennis (wasp) ENSOANP00000018378 Ornithorynchus anatinus (platypus) ENSORLP00000002327 Oryzias latipes (japanese killifish) PHUM004493-PA Pediculus humanus (human body louse) ENSPPYP00000012927 Pongo pygmaeus (orangutan) ENSPTRP00000024233 Pan troglodytes (chimpanzee) ENSRNOP00000002585 Rattus norvegicus (norway rat) Smp_042340 Schistosoma mansoni (trematode parasite) 13097 Trichoplax adhaerens (metazoa) XP_968711.2 Tribolium castaneum (red flour beetle) ENSTNIP00000009132 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000004883 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000013844 Xenopus tropicalis (frog) Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution • /genebrief/adherins_p120.htm InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 3355143 modMine - Data generated by the modENCODE project. • FBgn0260799 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10667 LH22593 ISCW015271 FBgn0223368 JGI_V11_327969 FBgn0141607 FBgn0129183 CPIJ005144 BGIBMGA005731 ACYPI008244 GB30504 GB30128 GB19511 AGAP011273 AAEL005461 PB24624 PHUM236350 GLEAN_01464
Synonyms & Secondary IDs ( 14 )
Reported As
Symbol Synonym	CG17484 (Peifer, 2000.4.6, Keleman et al., 2009.8.5) Dp120ctn (Tepass et al., 2001, Tepass, 1999) dP120ctn (Vidal et al., 2006) Dp120ctn (Kowalczyk and Moses, 2002, Myster et al., 2001, Cavallo et al., 1999) p120 (Marygold et al., 2005, Lee et al., 2003, Fox et al., 2004, Bain et al., 2004, Shimada et al., 2006, Tikhmyanova et al., 2010) P120 (Thiery, 2003) p120ctn (Jacinto et al., 2002, Magie and Parkhurst, 2003, Martin and Wood, 2002, Magie et al., 2002, Magie and Parkhurst, 2001, Kosik et al., 2005, Tepass and Harris, 2007) P120-catenin (Vidal et al., 2006) p120ctn (Rossi et al., 2007, Li et al., 2005, Yasuhara and Wakimoto, 2008, Larson et al., 2008, Spresser et al., 2008, Coulthard et al., 2010, Tikhmyanova et al., 2010, Di Stefano et al., 2011)
Name Synonym	Adherens junction protein p120 (Cavallo et al., 1996, ) Adherens-junction-protein-p120   p120 catenin (Visnyei et al., 2003) p120catenin (Fox et al., 2005, Li et al., 2005) P120-Catenin (Larson et al., 2008)
Secondary FlyBase IDs
	FBan0017484 FBgn0015587 FBgn0032995 FBgn0041583
References ( 59 )
Generate a list of	All references relating to this gene ( 59 )
List References by type	Research paper  ( 22 ) Supplementary material  ( 3 ) Review  ( 10 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 13 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 3 )
	Di Stefano et al., 2011, Genes Dev. 25(1): 17--28 Functional antagonism between histone H3K4 demethylases in vivo. [FBrf0212709] Coulthard et al., 2010, Genetics 185(2): 479--495 Essential loci in centromeric heterochromatin of Drosophila melanogaster. I: the right arm of chromosome 2. [FBrf0211235] Tikhmyanova et al., 2010, PLoS ONE 5(8): e12369 Dcas supports cell polarization and cell-cell adhesion complexes in development. [FBrf0211678] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...