FlyBase Gene Report: Dmel\Vps15

General Information

Symbol

Dmel\Vps15

Species

D. melanogaster

Name

Vacuolar protein sorting 15

Annotation Symbol

CG9746

Feature Type

protein_coding_gene

FlyBase ID

FBgn0260935

Gene Model Status

Current

Stock Availability

7 publicly available

Gene Summary

Vacuolar protein sorting 15 (Vps15) encodes a serine/threonine protein kinase that is a core component of the Vps34/class III PI3-Kinase complex. It is required for the production of PI3P and influences multiple vesicle trafficking pathways, including autophagy and endocytosis. [Date last reviewed: 2019-03-21] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

ird1, immune response deficient 1, immune response-deficient 1

Key Links

Genomic Location

Cytogenetic map

85D1-85D2

Sequence location

3R:9,240,757..9,245,869 [-]

Recombination map

3-48

RefSeq locus

NT_033777 REGION:9240757..9245869

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Help me choose

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (18 terms)

Molecular Function (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables ATP binding

inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290

(assigned by InterPro )

(FlyBase Curators et al., 2004-)

enables protein serine/threonine kinase activity

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

inferred from sequence or structural similarity with SGD:S000000301

(FlyBase Curators, 2008-)

Biological Process (12 terms)

Terms Based on Experimental Evidence (8 terms)

CV Term

Evidence

References

involved_in autophagy

inferred from mutant phenotype

(Xu et al., 2015, Juhász et al., 2008)

inferred from genetic interaction with FLYBASE:Pi3K59F; FB:FBgn0015277

(Juhász et al., 2008)

involved_in cellular response to amino acid starvation

inferred from mutant phenotype

(Wu et al., 2007)

involved_in epithelial structure maintenance

inferred from genetic interaction with FLYBASE:Lkb1; FB:FBgn0038167

(O'Farrell et al., 2017)

involved_in establishment or maintenance of cell polarity

inferred from genetic interaction with FLYBASE:Lkb1; FB:FBgn0038167

(O'Farrell et al., 2017)

involved_in larval midgut cell programmed cell death

inferred from mutant phenotype

(Xu et al., 2015)

involved_in macroautophagy

inferred from mutant phenotype

(Lindmo et al., 2008)

involved_in neuron remodeling

inferred from mutant phenotype

(Issman-Zecharya and Schuldiner, 2014)

involved_in regulation of antimicrobial peptide production

inferred from mutant phenotype

(Wu et al., 2007)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

involved_in autophagy of peroxisome

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in late endosome to vacuole transport

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in macroautophagy

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in protein phosphorylation

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

inferred from sequence or structural similarity with SGD:S000000301

(FlyBase Curators, 2008-)

involved_in protein targeting to vacuole

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

part_of phosphatidylinositol 3-kinase complex, class III, type I

inferred from direct assay

(Juhász et al., 2008)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

is_active_in late endosome

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

is_active_in nucleus-vacuole junction

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

part_of phosphatidylinositol 3-kinase complex, class III, type II

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

part_of phosphatidylinositol 3-kinase complex, class III, type I

inferred from biological aspect of ancestor with PANTHER:PTN000426471

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

AUTOPHAGY-SPECIFIC PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX

OTHER CONVENTIONAL PROTEIN KINASE DOMAIN KINASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

AUTOPHAGY-SPECIFIC PHOSPHATIDYLINOSITOL 3-KINASE COMPLEX -: The autophagy-specific phosphatidylinositol 3-kinase complex generates PI3-phosphate (PI3P) at the PAS (phagophore assembly site/preautophagosomal structure). (Adapted from FBrf0219844 and PMID:23999079).
OTHER CONVENTIONAL PROTEIN KINASE DOMAIN KINASES -: The group of 'other conventional protein kinase domain kinases' consists of kinases with a conventional eukaryotic protein kinase domain that do not fit into any of the other major groups. This grouping is described in FBrf0201870.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Vps15 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure New Section

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VHH2)

If you don't see the viewer to the right, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Comments on Gene Model

Gene model reviewed during 5.46

Sequence Ontology: Class of Gene

gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Vps15-RA

FBtr0081986

NM_141611

4239

1342

Vps15-RB

FBtr0301246

NM_001170094

2967

851

Vps15-RC

FBtr0333666

NM_001275476

2835

861

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

Vps15-PA

FBpp0081466

148.6

1342

6.80

NP_649868

AAF54342

Vps15-PB

FBpp0290464

95.9

851

6.71

NP_001163565

ACZ94862

Vps15-PC

FBpp0305822

97.1

861

6.58

NP_001262405

AGB95787

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Vps15 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

ird1_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

part_of phosphatidylinositol 3-kinase complex, class III, type I

inferred from direct assay

(Juhász et al., 2008)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Vps15 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Vps15

View exonic expression by tissue for Dmel\Vps15

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

41096/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0260935

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037663

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0260935

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9746

Flygut - An atlas of the Drosophila adult midgut

FBgn0260935

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 9 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Vps15

Transgenic constructs containing regulatory region of Vps15

Aberrations (Deficiencies and Duplications) ( 4 )

Inferred from experimentation ( 4 )

Gene disrupted in

Df(3R)Δvps15

(Lindmo et al., 2008)

Df(3R)Exel6152

(Ryder, 2004.4.26)

Gene partially disrupted in

Df(3R)D1^4A

(Weiler and Chatterjee, 2009)

Df(3R)D1^70-7

(Weiler and Chatterjee, 2009)

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal (with Df(3R)Δvps15)

Vps15⁵

lethal | recessive

Vps15^unspecified

Sterility

Allele

female semi-sterile, with Scer\GAL4^nos.PG, Scer\GAL4^VP16.nos.UTR, Scer\GAL4^VP16.otu

Vps15^HMS00908

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

Vps15^HMS04454

Other Phenotypes

Allele

abnormal cell polarity | somatic clone

Vps15⁵

abnormal immune response (with Vps15¹)

Vps15⁵

abnormal immune response (with Vps15⁵)

Vps15¹

abnormal immune response | recessive

Vps15^unspecified

abnormal neuroanatomy | adult stage | somatic clone

Vps15⁵

abnormal size | P-stage, with Scer\GAL4^NP0001

Vps15^HMS00908

abnormal starvation stress response | larval stage, with Scer\GAL4^Cg.PU

Vps15^HMS00908

decreased cell death | P-stage, with Scer\GAL4^NP0001

Vps15^HMS00908

decreased cell growth (with Vps15¹)

Vps15⁵

decreased cell growth (with Vps15⁵)

Vps15¹

melanotic mass phenotype

Vps15^unspecified

Phenotype manifest in

Allele

autophagosome | somatic clone

Vps15³

embryonic/larval fat body (with Vps15¹)

Vps15⁵

embryonic/larval fat body (with Vps15⁵)

Vps15¹

embryonic/larval fat body | larval stage, with Scer\GAL4^Cg.PU

Vps15^HMS00908

embryonic/larval midgut | P-stage, with Scer\GAL4^NP0001

Vps15^HMS00908

eye-antennal disc | larval stage | somatic clone

Vps15⁵

fat body | somatic clone

Vps15³

follicle cell | somatic clone

Vps15⁵

gamma Kenyon cell | adult stage | somatic clone

Vps15⁵

gastric caecum | P-stage, with Scer\GAL4^NP0001

Vps15^HMS00908

imaginal disc epithelial cell | somatic clone

Vps15⁵

melanotic mass

Vps15^unspecified

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\PIK3R4

15 of 15

Yes

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Pik3r4

14 of 15

Yes

Rattus norvegicus (Norway rat) (1)

Rnor\Pik3r4

13 of 13

Yes

Xenopus tropicalis (Western clawed frog) (1)

Xtro\pik3r4

3 of 12

Yes

Danio rerio (Zebrafish) (1)

Drer\pik3r4

11 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (1)

Cele\vps-15

14 of 15

Yes

Arabidopsis thaliana (thale-cress) (1)

Atha\VPS15

9 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (1)

Scer\VPS15

13 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\ppk19

10 of 12

Yes

Other Organism Orthologs (via OrthoDB)

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (0)

No records found.

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

PIK3R4; phosphoinositide-3-kinase regulatory subunit 4

15 of 15

602610

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Vps15 - Rab5

pull down, peptide massfingerprinting

(Gillingham et al., 2014, Gillingham et al., 2014)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Vps15

suppressible

Lkb1

(O'Farrell et al., 2017)

Ras85D|Vps15

suppressible

Lkb1

(O'Farrell et al., 2017)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Ras85D

enhanceable

Vps15

(O'Farrell et al., 2017)

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0260935

MIST (protein-protein) - An integrated Molecular Interaction Database

Vps15

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0260935

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-48

Cytogenetic map

85D1-85D2

Sequence location

3R:9,240,757..9,245,869 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

85D1-85D2

Limits computationally determined from genome sequence between P{EP}D1^EP473 and P{PZ}Aats-trp⁰³⁵⁵⁹

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

3-48

(FlyBase, 2016)

3-46.0

(Comeron et al., 2012)

(Wu et al., 2001)

Left of (cM)

(Wu et al., 2001)

Right of (cM)

P{EP}D1^EP473

(Wu et al., 2007)

(Wu et al., 2001)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

35209

y¹ sc^* v¹ sev²¹; P{TRiP.GL00085}attP2

83822

y¹ sc^* v¹ sev²¹; P{TKO.GS04506}attP40

34092

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00908}attP2

57011

y¹ sc^* v¹ sev²¹; P{TRiP.HMS04454}attP40

42118

y¹ w^*; Mi{MIC}Vps15^MI05805/TM3, Sb¹ Ser¹

VDRC

v110706

P{KK101889}VIE-260B

v341008

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00009}attP40/CyO-GFP

Genomic Clones (16)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (66)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

FI23917

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0260935

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

GH05641

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0260935

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

41096

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: Vps15 ird1

(FlyBase, 2009-)

Source for database merge of

Source for merge of: ird1 CG9746

(Wu et al., 2007)

Additional comments

Renamed from the placeholder symbol 'ird1' to 'Vps15', which is a well-used synonym and more informative.

(FlyBase, 2009-)

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

Identification: as a mutation that fails to induce expression of Ecol\lacZ^Dpt.PR normally in response to infection. 2 alleles have been obtained.

(Wu et al., 2001)

Components of the immune response are identified in a screen for the failure to induce a Dpt (an antibacterial peptide) Ecol\lacZ reporter gene.

(Wu and Anderson, 1998)

Mutants are impaired in their induction of Dpt, but show distinct regulation of the two transcription factors, dl and Dif, implicated in the immune response.

(Wu and Anderson, 1998)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 59 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

41096

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VHH2

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VHH2

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0260935

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

41096/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0260935

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

ird1_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0037663

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0260935

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG9746

Flygut - An atlas of the Drosophila adult midgut

FBgn0260935

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0260935

FlyMine - An integrated database for Drosophila genomics

FBgn0260935

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

41096

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC012433

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG9746

MARRVEL_MODEL - MARRVEL (model organism gene)

41096

modMine - A data warehouse for the modENCODE project

FBgn0260935

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

E1JIG3

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0260935

DRSC - Results frm RNAi screens

FBgn0260935

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

MIST (protein-protein) - An integrated Molecular Interaction Database

Vps15

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (13)

Reported As

Symbol Synonym

CG9746

(Érdi et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Ni et al., 2011.7.19, Arancio et al., 2010, Ni et al., 2010.12.1, Wendler et al., 2010, Abe et al., 2009, Jiang et al., 2009, Keleman et al., 2009.8.5, Weiler and Chatterjee, 2009, Lindmo et al., 2008, Weiler, 2007, Wu et al., 2007, Molnar et al., 2006, Birch-Machin et al., 2005, Rehmsmeier et al., 2004)

FBgn0260935

(Im and Lazzaro, 2018)

Ird1

(Im and Lazzaro, 2018, Faisal et al., 2014, Juhász et al., 2008)

VPS15

(Denton et al., 2015)

dVps15

(Abe et al., 2009)

ird

(Wasserman, 2000)

ird1

(Denton et al., 2020, Banerjee et al., 2019, O'Keefe and Denton, 2018, Kuleesha et al., 2016, Schmid et al., 2016, Xu et al., 2015, Sopko et al., 2014, Moy and Cherry, 2013, Érdi et al., 2012, Powis and Macdougall, 2011, Zirin and Perrimon, 2010, Wu et al., 2007)

p150

(Abe et al., 2009)

vps15

(Issman-Zecharya and Schuldiner, 2014, Lindmo et al., 2008)

Name Synonyms

CG9746

Vacuolar protein sorting 15

immune response deficient 1

(Faisal et al., 2014, Wu and Anderson, 1998)

immune response-deficient 1

(Lindmo et al., 2008, Wu et al., 2007)

Secondary FlyBase IDs