Gene Dmel\mwh

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Diaphanous FH3 (IPR010472)

GTPase-binding/formin homology 3 (IPR014768)

Diaphanous GTPase-binding (IPR010473)

Armadillo-type fold (IPR016024)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9W0J2

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

pupal stage P7 -- pharate adult stage P15

wing hair

Comment:from 30 hours APF on

wing | restricted

Comment:from 30 hours APF on

Additional Descriptive Data

mwh protein was observed in wing cells after 30 hours APF. It was observed in an uneven zigzag staining pattern at the cell periphery and accumulates near adherens junctions. It accumulates in both growing and emerging wing hairs and accumulates preferentially in the proximal part of the hair and not in the base at that time. Later in hair morphogenesis (after 36 hr APF), it accumulates preferentially in the base of the hairs.

(The modENCODE Consortium, 2010)

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0260963

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	max expr for FBgn0260963
	Very low expression bin max
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages, during late pupal stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No expression (0 - 0)
	Extremely low expression (1 - 10)
	Very low expression (11 - 100)
	Low expression (101 - 400)
	Moderate expression (401 - 1400)
	Moderately high expression (1401 - 4000)
	High expression (4001 - 10000)
	Very high expression (10001 - 100000)
	Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0260963 expression level
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		3849
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High

Linear, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		(274)
embryo 08-10hr		(431)
embryo 10-12hr		(1203)
embryo 12-14hr		(2180)
embryo 14-16hr		(2423)
embryo 16-18hr		(612)
embryo 18-20hr		(402)
embryo 20-22hr		(130)
embryo 22-24hr		(131)
larva L1		(129)
larva L2		(1198)
larva L3 12hr old		(239)
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		(109)
white prepupae 12hr		(303)
white prepupae 24hr		(568)
pupae 2d postWPP		(3849)
pupae 3d postWPP		(615)
pupae 4d postWPP		(214)
adult male 01day		(289)
adult male 05day		(266)
adult male 30day		(292)
adult female 01day		(168)
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		(2180)
embryo 14-16hr		(2423)
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		(3849)
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		3849
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		3849
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to maximum FBgn0260963 expression level
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		3849
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High

log, scaled to Very low expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		(274)
embryo 08-10hr		(431)
embryo 10-12hr		(1203)
embryo 12-14hr		(2180)
embryo 14-16hr		(2423)
embryo 16-18hr		(612)
embryo 18-20hr		(402)
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		(1198)
larva L3 12hr old		(239)
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		(303)
white prepupae 24hr		(568)
pupae 2d postWPP		(3849)
pupae 3d postWPP		(615)
pupae 4d postWPP		(214)
adult male 01day		(289)
adult male 05day		(266)
adult male 30day		(292)
adult female 01day		(168)
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		(3849)
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		3849
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		20
embryo 02-04hr		26
embryo 04-06hr		43
embryo 06-08hr		274
embryo 08-10hr		431
embryo 10-12hr		1203
embryo 12-14hr		2180
embryo 14-16hr		2423
embryo 16-18hr		612
embryo 18-20hr		402
embryo 20-22hr		130
embryo 22-24hr		131
larva L1		129
larva L2		1198
larva L3 12hr old		239
larva L3 puffstage 1-2		66
larva L3 puffstage 3-6		47
larva L3 puffstage 7-9		78
white prepupae new		109
white prepupae 12hr		303
white prepupae 24hr		568
pupae 2d postWPP		3849
pupae 3d postWPP		615
pupae 4d postWPP		214
adult male 01day		289
adult male 05day		266
adult male 30day		292
adult female 01day		168
adult female 05day		47
adult female 30day		61
Expression Level Scale		None Extremely low Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

FlyAtlas Anatomical Expression Data for FBgn0260963

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	max expr for FBgn0260963
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0260963 expression level
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate High Very high

log, scaled to maximum FBgn0260963 expression level
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		0.825
Larval Midgut		no informative data
Larval Hindgut		5
Larval Malpighian Tubules		0.8
Larval Fat Body		2
Larval Salivary Gland		1.2
Larval Trachea		6.075
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye		75.275
Adult Brain		1
Adult Thoracic-Abdominal Ganglion		1.8
Adult Crop		1.6
Adult Midgut		no informative data
Adult Hindgut		1.3
Adult Malpighian Tubules		8.9
Adult Fat Body		3.7
Adult Salivary Gland		3.1
Adult Heart		3.15
Adult VirginFemale Spermatheca		3.1
Adult InseminatedFemale Spermatheca		1.2
Adult Ovary		0.7
Adult Testis		1.2
Adult Male Accessory Gland		no informative data
Adult Carcass		7.9
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut		no informative data
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass		no informative data
Adult Head		no informative data
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut		no informative data
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland		no informative data
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	no informative data
NA	Eye	75.275
NA	Brain	1
0.825	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	1.8
NA	Crop	1.6
no informative data	Midgut	no informative data
5	Hindgut	1.3
0.8	Malpighian Tubules	8.9
2	Fat Body	3.7
1.2	Salivary Gland	3.1
NA	Heart	3.15
6.075	Trachea	NA
NA	VirginFemale Spermatheca	3.1
NA	InseminatedFemale Spermatheca	1.2
NA	Ovary	0.7
NA	Testis	1.2
NA	Male Accessory Gland	no informative data
no informative data	Carcass	7.9

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

mE2_34_mRNA_expression_cluster_07

External Data & Images

planar polarity defective

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

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FBgn0260963

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

mwh¹

viable, with Scer\GAL4^pnr-MD237

mwh^GD8165

Other Phenotypes

Allele

body color defective, with Scer\GAL4^pnr-MD237

mwh^GD8165

planar polarity defective, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

planar polarity defective | cell autonomous | somatic clone

mwh¹

planar polarity defective | heat sensitive

mwh⁶

visible

mwh¹

visible, with Scer\GAL4^ap-md544

mwh^GD8165

visible, with Scer\GAL4^pnr-MD237

mwh^GD8165

visible, with Scer\GAL4^ptc-559.1

mwh^GD8165

visible, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

visible | adult stage | recessive | somatic clone

mwh^unspecified

visible | heat sensitive

visible | heat sensitive (with mwh¹)

mwh⁶

visible | heat sensitive (with mwh⁶)

mwh¹

visible | recessive

Phenotype manifest in

Allele

actin filament

mwh¹

denticle belt

mwh¹

mesothoracic tergum, with Scer\GAL4^pnr-MD237

mwh^GD8165

microchaeta

mwh¹

microchaeta & wing

mwh¹

trichogen cell, with Scer\GAL4^pnr-MD237

mwh^GD8165

trichome & adult head | dorsal | somatic clone

mwh^unspecified

wing | pupal stage

mwh¹

wing cell

mwh¹

wing hair

wing hair, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

wing hair | cell autonomous | somatic clone

mwh¹

wing hair | cell autonomous | somatic clone | supernumerary

mwh^unspecified

wing hair | heat sensitive

mwh⁶

wing hair | supernumerary

wing hair | supernumerary, with Scer\GAL4^ap-md544

mwh^GD8165

wing hair | supernumerary, with Scer\GAL4^ptc-559.1

mwh^GD8165

wing hair | supernumerary, with Scer\GAL4^ptc-559.1, Scer\GAL4^tub.PU

mwh^Scer\UAS.cYa

wing hair | supernumerary | heat sensitive

mwh⁶

wing hair | supernumerary | heat sensitive (with mwh¹)

mwh⁶

wing hair | supernumerary | heat sensitive (with mwh⁶)

mwh¹

Classical Alleles ( 11 )

For All Classical Alleles Show

Allele of mwh	Class	Mutagen	Stocks	Known lesion
mwh¹	amorphic allele - genetic evidence, loss of function allele	spontaneous	310	Yes
mwh²	loss of function allele		1	Yes
mwh^MB09358			1	--
mwh⁺			0	--
mwh³	loss of function allele		0	Yes
mwh⁴	loss of function allele		0	Yes
mwh⁵	loss of function allele		0	Yes
mwh⁶	hypomorphic allele - genetic evidence		0	Yes
mwh^RdeMed			0	--
mwh^semi		spontaneous	0	--
mwh^unspecified			0	--

Alleles Carried on Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Allele of mwh	Mutagen	Stocks	Known lesion
mwh^GD8165	in vitro construct - RNAi in vitro construct - regulatory fusion	3	Yes
mwh^HMS00180	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
mwh^{Act5C.T:Avic\GFP-EGFP}	FLPase	0	Yes
mwh^C.Scer\UAS	in vitro construct - regulatory fusion	0	Yes
mwh^{GBD.FH3.Scer\UAS.T:Ivir\HA1}	in vitro construct - regulatory fusion in vitro construct - coding region fusion	0	Yes
mwh^{Scer\FRT.Act5C.T:Avic\GFP-EGFP}	in vitro construct - regulatory fusion	0	Yes
mwh^Scer\UAS.cYa	in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Duplicated in

Dp(1;YS)sc^V1mwh⁺

Dp(3;Y;1)M1

(Garcia-Bellido and Ripoll, 1973)

Dp(3;Y;1)M2

(Garcia-Bellido and Ripoll, 1973)

Dp(3;Y;1)M3

(Garcia-Bellido and Ripoll, 1973)

T(Y;3)P6

Ts(Y;3Lt)P5

(Lewis, 1969)

Ts(YSt;3Lt)D8

(Smith et al., 1985)

Not duplicated in

Dp(3;4)h⁺44

(Ingham et al., 1985)

Ts(Y;3Lt)P3

(Lewis, 1969)

Not disrupted in

Df(3L)h-i22

(Ingham et al., 1985)

Tp(3;3)h^M3

(Ingham et al., 1985)

Disrupted in

In(3L)mwh¹

Partially disrupted in

In(3L)mwh¹

P{Act5C(FRT.polyA)EGFP-mwh}

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{TRiP.HMS00180}

P{UAS-mwh.C}

P{UAS-mwh.HA.GBD.FH3}

P{UAS-mwh.Y}

characterization construct

P{Act5C(-FRT)EGFP-mwh}

P{UAS-in::mwh.L}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap binary system

Mi{ET1}mwh^MB09358

Gene Ontology: Function, Process & Cellular Component ( 8 unique terms )

Terms Based on Experimental Evidence ( 4 terms )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

imaginal disc-derived wing hair organization

inferred from mutant phenotype

(Cong et al., 2001, Yan et al., 2008)

imaginal disc-derived wing hair site selection

inferred from mutant phenotype

imaginal disc-derived wing morphogenesis

inferred from mutant phenotype

(Cong et al., 2001)

negative regulation of actin filament polymerization

inferred from mutant phenotype

(FlyBase Curators et al., 2004-)

Cellular Component ( 0 terms)

Terms Based on Predictions or Assertions ( 4 terms )

Molecular Function

CV term

Evidence

References

actin binding

inferred from electronic annotation with InterPro:IPR010472, InterPro:IPR010473

Rho GTPase binding

inferred from electronic annotation with InterPro:IPR010473

(FlyBase Curators et al., 2004-)

Biological Process

CV term

Evidence

References

establishment of planar polarity

traceable author statement

(Mlodzik, 2002)

Wnt receptor signaling pathway

traceable author statement

(Cong et al., 2001)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

mwh allele

Gene

References

mwh¹

(Lee and Adler, 2002)

ultA

(Adler et al., 2000)

External Data

BioGRID - A database of protein and genetic interactions

•

63677

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0260963

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

38131

Orthologs

Genome-wide drosophilid orthologs

Dana\GF24439

Dere\GG14764

Dgri\GH15487

Dmoj\GI16764

Dper\GL16160

Dpse\GA12621

Dsec\GM14384

Dvir\GJ12509

Dwil\GK21125

Dyak\GE21127

Curated drosophilid orthologs

Dpse\GA12621

InParanoid A subset of ortholog calls from InParanoid.

•

AAEL008269-PA
Aedes aegypti (mosquito)
AGAP004761-PA
Anopheles gambiae (mosquito)
XP_393985.2
Apis mellifera (honey bee)
XP_001946564.1
Acyrthosiphon pisum (pea aphid)
BGIBMGA005540-PA
Bombyx mori (silk worm)
CPIJ014675
Culex pipens (mosquito)
326379
Daphnia pulex (daphnia)
ISCW020548-PA
Ixodes scapularis (deer tick)
PHUM006556-PA
Pediculus humanus (human body louse)
ENSPTRP00000054871
Pan troglodytes (chimpanzee)
XP_971593.1
Tribolium castaneum (red flour beetle)

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

Stocks & Reagents

Stocks Listed in FlyBase ( 316 )

Bloomington

549

mwh¹

677

y¹; mwh¹

5747

Dp(3;3)Cam37, mwh¹/TM1

2558

mwh¹ ry⁵⁰⁶ e¹

101704

105974

101892

108403

Dp(3;3)Cam37, mwh¹/TM1

107402

mwh¹ ry⁵⁰⁶ e¹

VDRC

v41513

w¹¹¹⁸; P{GD8165}v41513

v41514

w¹¹¹⁸; P{GD8165}v41514

v45265

w¹¹¹⁸; P{GD8165}v45265

More stocks available...

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 107 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

RE53394

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

(Strutt and Warrington, 2008, Yan et al., 2008)

DRSC - Results from RNAi screens.

•

FBgn0260963

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

Antibody Information

polyclonal

Other Information

Discoverer

di Pasquale, Dec. 1950.

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Source for merge of: mwh CG13913

Additional comments

Other Comments

mwh appears to function as a repressor of actin filament formation, restricting the production of actin-rich prehairs to distal cell edges in the pupal wing.

mwh has two temporally separate functions in wing development; early proximal mwh protein accumulation restricts hair initiation to the distal side of wing cells, while the later accumulation of mwh protein in the wing hair prevents the formation of ectopic secondary wing hairs.

(Guzman Rincon et al., 1998)

Functions downstream of fz for planar polarity in the wing.

(Lee and Adler, 2002)

mwh is epistatic to in and fy.

(Lee and Adler, 2002)

The genotoxicity of six insecticides has been analysed using the wing spot test.

(Osaba et al., 1999)

The wing spot test has been used to assay the antigenotoxicity of a number of compounds.

(Graf et al., 1998)

SMART is well suited for the determination of genotoxicity produced by in vivo nitrosation processes and for the study of their modulation by individual compounds or dietary complex mixtures.

The genotoxic effect of the essential oils of O.vulgare, C.capitata and S.thymbra is tested using the SMART assay: the oils do not show any mutagenic or recombinagenic activity.

(Karpouhtsis et al., 1998)

The genotoxic effect DEHP is tested using the SMART assay, results reveal DEHP does not have a genotoxic effect.

(Kawai, 1998)

The genotoxic effect of 4 inhibitors of DNA topoisomerases has been studied using the wing spot assay.

(Torres et al., 1998)

Ethanol reduces the mutagenic effect of γ-irradiation in SMART assay, mainly by decreasing the frequency of mitotic recombination.

(Zakharenko and Zakharov, 1998)

The genotoxic effect of integerrimine (ITR) are analysed using the wing spot test: ITR is genotoxic.

(Campesato et al., 1997)

Definitive denticle belt phenotypes (abnormal hairs and/or bristles) are foreshadowed by abnormal organisation of the actin cytoskeleton in embryonic epidermal cells.

(Dickinson and Thatcher, 1997)

Vicinal chloroalcohols are investigated for genotoxicity in the wing spot test (SMART): tested compounds are non-genotoxic in this in vivo assay.

(Frei and Wurgler, 1997)

Sodium azide is tested for somatic mutation and mitotic recombination induction in wing imaginal disc cells using the wing spot test. Sodium azide induces exclusively mitotic recombination in wing somatic cells after chronic exposure. This activity is reduced in the presence of high bioactivation capacity.

(Gonzalez-Cesar and Ramos-Morales, 1997)

The genotoxic effect PhIP is tested using the SMART assay, results reveal PhIP has a DNA-damaging activity.

(Kasai et al., 1997)

The mutagenic and/or carcinogenic activity of electromagnetic fields is estimated using the wing spot test in larvae, exposure causes a statistically significant enhancement of somatic recombination. Supplement of vitamin E suppresses this enhancement.

(Koana et al., 1997)

Wing spots in the SMART reveal enzyme-sulfhydryl blocking agents, such as MMTS and DPDS, are effective antimutagens in vivo.

(Nakamura et al., 1997)

The effect of chlorophyll on the genotoxic activity of 4-nitroquinoline 1-oxide has been studied using the wing spot test.

(Negishi et al., 1997)

The genotoxic effects of N-nitroso-N-methylurea (MNU) and acetone oxime (ACOX) are tested using the SMART test. The effect of Hsap\GST on the genotoxic effect is studied: flies carrying three or more copies of Hsap\GST are significantly more resistant to the genotoxic effect of ACOX.

(Ryskova et al., 1997)

SMART is used to test the genotoxic effect of fullerene C-60: only at the highest possible fullerene concentration a slight genotoxic effect was observed in wing cells.

(Zakharenko et al., 1997)

Only the maximum possible content of fullerene C₆₀ produces a slight genotoxic effect when using the SMART test.

(Zakharenko et al., 1997)

Assays of a series of compounds in the wing spot test indicates the single mwh spots appear most frequently, followed by less frequent twin spots and then the quite rare flr spots. Some compounds behave in this manner, others do not in that the frequency of single flr spots is equal to or exceeds that of twin spots.

(Zimmering et al., 1997)

The mwh/flr wing spot test has been used to assay four inhibitors of eukaryotic topoisomerases for genotoxic effects.

(Frei and Wurgler, 1996)

The spectrum of genotoxic events detected by the wing somatic mutation and recombination test (SMART) and the wⁱ eye spot test is different. The wⁱ eye spot test appears not to detect mitotic recombination the way the wing spot test does.

(Graf and Wuergler, 1996)

The genetic effects of exposure to a range of concentrations of alpha particles has been studied using the wing-spot test.

(Pimentel et al., 1996)

Six alkylating agents have been ranked as follows according to their genotoxic potency in the wing spot test: methyl methanesulfonate > mitomycin C > N-dimethylnitrosamine > chlorambucil ~ monocrotaline > N-diethylnitrosamine.

(Rodriguez-Arnaiz et al., 1996)

The mwh/flr wing spot test has been used to assay for genotoxic effects of griseofulvin.

(Tripathy et al., 1996)

The mwh/flr wing spot test has been used to assay for genotoxicity of tetracycline hydrochloride.

(Tripathy et al., 1996)

The genotoxicity of 6 phenazine and aminophenazine derivatives is assayed using the wing spot test in larvae, chemicals exhibit significant mutagenicity.

(Watanabe et al., 1996)

The relative biological effectiveness of ²⁵²Cf neutrons has been determined for two different types of somatic mutations, the wing-spot test (using mwh and flr) and reversion of eye-colour (using w).

(Yoshikawa et al., 1996)

Gamma ray induced somatic clones of wing cells demonstrates the level of induction of mwh-like structures consisting of two trichomes and of true mwh mutations is the same if the former are located on the wing surface. These twi-trichome structures must be taken into account when using the mwh type spots in the method of somatic mosaics of wing cells.

(Zakharenko and Zakharov, 1996)

Three assays (z-w, wⁱ and wing spot) are used to evaluate the genotoxic response of five chemicals classified as genotoxic non-carcinogens, chemicals significantly increase the frequency of mutant clones.

(Batiste-Alentorn et al., 1995)

The effects of 10 carcinogens on the wing spot test are evaluated.

(Batiste-Alentorn et al., 1995)

The mwh/flr wing spot test has been used to test for any genotoxic effects of tannic acid.

(Cunha et al., 1995)

The wing somatic mutation and recombination test (SMART) of larvae is used to evaluate the genotoxicity of three polycyclic aromatic hydrocarbons (PAHs) and three of their nitro derivatives, genotoxic activity can be detected in somatic cells.

(Delgado-Rodriguez et al., 1995)

In young larvae only a few but very large spots are induced by application of a mutagen in the wing spot test. In older larvae the frequency is considerably increased but the sizes are smaller. Practically no twin spots (result of mitotic recombination) are found in young or in very old larvae. Results demonstrate the optimal age of the larvae for mutagen treatment is 72 hours.

(Graf, 1995)

Wing spot test is used to evaluate the genotoxic effect of griseofulvin in somatic larval cells, griseofulvin is genotoxic in somatic cells.

(Inoue et al., 1995)

Genotoxic activity in vivo of the naturally occurring glucoside, cycasin, is assayed in the wing spot test.

(Kawai et al., 1995)

Ascorbic acid (vitamin C), when used as a pretreatment, protects against mutation/recombination induced by γ rays and chromium (VI) oxide in larvae in the wing spot test.

(Olvera et al., 1995)

The mwh/flr wing spot test has been used to assay the genotoxicity of aflatoxin B₁ and aflatoxin M₁.

(Shibahara et al., 1995)

Wing spot test reveals two triazine herbicides, terbutryn and terbuthylazin, are genotoxic in the wing primordia.

(Tripathy et al., 1995)

Wing spot test reveals the triazine herbicide, simazine, is genotoxic in the wing primordia.

(Tripathy et al., 1995)

The attached X and mwh/flr spot test system were used to demonstrate that ginseng and Salvia miltiorrhiza have inhibitory effects on the in vivo mutagenicity induced by N-methyl-N-nitro-N-nitrosoguanidine (MNNG) during spermatogenesis.

(Choi et al., 1994)

Arsenic acid has an inhibitory effect on the induction of wing spots by gamma irradiation or alkylating agents in a wing-spot assay.

(de la Rosa et al., 1994)

The wing spot test has been used to demonstrate that the somatic mutation and recombination test can be used for the genotoxic activity of alcoholic and non-alcoholic beverages.

(Graf et al., 1994)

The adenine derivatives, (R,S)-9-(2,3-dihydroxypropyl)adenine, D-eritadenine and 9-(2-phosphonylmethoxyethyl)adenine, are potent inducers of both single spots and twin spots in a wing-spot assay.

(Marec and Gelbic, 1994)

Wing spot tests rank the genotoxic effectiveness of a number of metal salts in the following order: CoCl₂> ZnCl₂> MoCl₃> (MnCl₂, NiCl₂).

(Ogawa et al., 1994)

Somatic mutation and recombination test (SMART) is used to determine the relevance of the in vitro effects induced by benzophenone-3: benzophenone-3 is not genotoxic.

(Robison et al., 1994)

Chloral hydrate is recombinogenic in the wing spot test.

(Zordan et al., 1994)

Wing-spot assay is used to evaluate the quantitative relationship between BaP-DNA adduct formation, determined by ³²P-postlabelling, and the induction of phenotypically mutant cells.

(Zordan et al., 1994)

High temperatures cause a small number of mwh spots in the wing-spot assay and cold temperatures yield much greater number of single spots.

(Katz and Foley, 1993)

The effect of chlorophyllin on the genotoxicity of chromium(VI) oxide in larvae transheterozygous for mwh and flr is assayed using the wing spot somatic test.

(Olvera et al., 1993)

The somatic mutation and recombination test (SMART) in wing cells of three day old larvae transheterozygous for mwh and flr is used to study the mutagenic potential of three benzo^cphenanthridine alkaloids with antileukemic properties as compared with that of two structurally related aromatic polycyclic hydrocarbons.

(Perez-Chiesa and Rodriguez, 1993)

The wing spot test is used to evaluate the genotoxicity of the antitumour indenoisoquinoline analogues of nitidine chloride and fagaronine chloride in larvae transheterozygous for mwh and flr, the analogues have a very weak genotoxic effect.

(Perez-Chiesa and Narvaez, 1993)

Wing spot tests indicate that 2,4-dichlorophenoxyacetic acid is genotoxic in the primordial wing cells of Drosophila.

(Tripathy et al., 1993)

The wing spot test has been used to demonstrate that atrazine is genitoxic to the wing disc cells and male germline cells.

(Tripathy et al., 1993)

Four antidepressants and one neuroleptic drug are tested for genotoxicity using the somatic mutation and recombination test (SMART) in wing cells of three day old larvae transheterozygous for mwh and flr, the compounds are genotoxic.

(van Schaik and Graf, 1993)

The genotoxicity of mitoxantrone has been assayed using the mwh-flr wing spot test.

(Frei et al., 1992)

The genotoxicity of p-dimethylaminoazobenzene has been analysed using the mwh-flr wing spot test.

(Graf et al., 1992)

Chromium(VI) oxide is highly genotoxic in the mwh-flr wing spot assay.

(Graf et al., 1992)

The wing spot test has been used to demonstrate that chloral hydrate is genitoxic to the wing disc cells and male germline cells.

(Patnaik et al., 1992)

The genotoxicity of chlorpyrifos (Durmet) has been assayed using the mwh-flr wing spot test.

(Patnaik and Tripathy, 1992)

The genotoxicity of tritiated water has been assayed using the mwh-flr wing spot test.

(Ribas et al., 1992)

The genotoxicity of furfural has been assayed using the mwh-flr wing spot test.

(Rodriguez-Arnaiz et al., 1992)

The genotoxicity of four herbicides (alachlor, atrazine, maleic hydrazide and paraquat) has been assayed using the mwh-flr wing spot test.

(Torres et al., 1992)

The mwh-flr wing spot test has been used to assay the genotoxicity of the insecticide Parryfos (monocrotophos).

(Tripathy and Patnaik, 1992)

Wild type allele of mwh is present on Dp(3;f)Th and displays mosaic expression on the wings.

(Wines and Henikoff, 1992)

The genotoxicity of irradiated cocoa has been assayed using the mwh-flr wing spot test.

(Zimmering et al., 1992)

Somatic mutation in hybrid dysgenic flies has been assayed using the mwh-flr wing spot test.

(Getz and van Schaik, 1991)

The genotoxicity of a series of N-nitrosamines has been assayed using the mwh-flr wing spot test.

(Negishi et al., 1991)

The mutagenicity of tepezcohuite has been assayed using the wing spot test.

(Pimentel et al., 1991)

The wing spot test has been used to assay the mutagenic activity of a number of polycyclic aromatic hydrocarbons.

(Sato et al., 1991)

Genotoxicity of acrolein is investigated using SMART, SCLT (sex chromosome loss test) and SLRLT (sex linked recessive lethal test). Acrolein is mutagenic in SLRLT when injected but not fed, SCLT does not reveal a clastogenic effect with acrolein and acrolein has a genotoxic effect in SMART.

(Sierra et al., 1991)

The mutagenic and recombinogenic activity of 3-beta-hydroxy-13-alpha-amino-13,17-seco-5-alpha-androstan-17-oic-13,17-lactam-p-bis-(2-chloroethyl) aminophenoxyacetate (NSC 294859) has been assayed using a wing somatic mutation and recombination test (SMART).

(Stephanou et al., 1991)

Acrylamide is both mutagenic and recombinogenic in wing disc cells and induces sex-linked recessive lethals.

(Tripathy et al., 1991)

Wing spot test (SMART) and sex-linked recessive lethal test (SLRLT) are used to test the mutagenicity of sumithion, a broad spectrum insecticide - compound is mutagenic in wing primordial cells and induces recombination at high doses.

(Tripathy and Patnaik, 1991)

SMART in wing cells is used to test genotoxicity of 5 tricyclic antidepressants, results implicate the nitrogen atom at position 5 in the 7-membered ring of the tricyclic molecule as being responsible for the genotoxic property of the compounds.

(van Schaik and Graf, 1991)

Genotoxicity of a chelating agent, nitrilotriacetic acid (NTA), is investigated using SMART. NTA is active in inducing mitotic recombination and possible aneuploidy in somatic cells.

(Zordan et al., 1991)

The effects of chemicals classified as non-carcinogens or unclassified, but known to have given one or more positive results, are tested using SMART. Also the sensitivity of SMART compared to SLRLT is tested.

(Eiche et al., 1990)

Genotoxicity of ethyl carbamate is tested using SMART: ethyl carbamate induces, in a dose-dependent manner, single as well as twin spots, indicating a recombinogenic activity.

(Frolich and Wurgler, 1990)

The effects of repair deficiency are studied by comparing the frequency of somatic mutation and mitotic recombination in repair proficient female progeny with that in excision repair defective male progeny. Nine chemical mutagens with various modes of action are tested in this way.

(Graf et al., 1990)

The genetic toxicity of six carcinogens and six non-carcinogens are tested using SMART: carcinogens are highly toxic and the non-carcinogens are non-genotoxic.

(Tripathy et al., 1990)

The genotoxic activity of a photochemical reaction mixture of 1,3-butadiene and nitrogen dioxide has been assayed using the wing spot test.

(Victorin et al., 1990)

SMART is used to assay the effects of NTA and EDTA in germ and somatic cell lines.

(Zordan et al., 1990)

Mutant alleles are useful as markers in clonal analysis.

(Lawrence et al., 1986)

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_138238

RefSeq (Proteins)

•

NP_612082

DDBJ / EMBL / GenBank

•

AAF47454

Entrez Gene - A searchable database of RefSeq genes.

•

38131

UniProtKB/TrEMBL

•

Q9W0J2

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Diaphanous FH3 (IPR010472)

GTPase-binding/formin homology 3 (IPR014768)

Diaphanous GTPase-binding (IPR010473)

Armadillo-type fold (IPR016024)

Linkouts

BioGRID - A database of protein and genetic interactions

•

63677

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0260963

DRSC - Results from RNAi screens.

•

FBgn0260963

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0260963

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0260963

FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways

•

450718

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

InParanoid A subset of ortholog calls from InParanoid.

•

AAEL008269-PA
Aedes aegypti (mosquito)
AGAP004761-PA
Anopheles gambiae (mosquito)
XP_393985.2
Apis mellifera (honey bee)
XP_001946564.1
Acyrthosiphon pisum (pea aphid)
BGIBMGA005540-PA
Bombyx mori (silk worm)
CPIJ014675
Culex pipens (mosquito)
326379
Daphnia pulex (daphnia)
ISCW020548-PA
Ixodes scapularis (deer tick)
PHUM006556-PA
Pediculus humanus (human body louse)
ENSPTRP00000054871
Pan troglodytes (chimpanzee)
XP_971593.1
Tribolium castaneum (red flour beetle)

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

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38131

modMine - Data generated by the modENCODE project.

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FBgn0260963

OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.

Synonyms & Secondary IDs ( 6 )

Reported As

Symbol Synonym

CG13913

(Staudt et al., 2005, Strutt and Warrington, 2008, Yan et al., 2008, Ni et al., 2011.7.19)

Name Synonym

CG13913

multiple wing hair

(Fanto and McNeill, 2004, Rajan et al., 2009, Taira et al., 2005, do Amaral et al., 2005, Cruces et al., 2009, Zakharenko and Perepelkina, 2009)

multiple wing hairs

(He and Adler, 2002, Goodman et al., 2006, Quaiser, 2006, Taylor and Adler, 2008, Hirano et al., 2009, Fang and Adler, 2010, Castro et al., 2008, Pataki et al., 2010, Lu et al., 2010, Romero-Jimenez et al., 2005, Heres-Pulido et al., 2008, Carmona et al., 2011)

multiple Wing Hairs

multiple-wing-hairs