Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\alc using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\alc in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
alc null mutants exhibit mortality at a range of developmental stages (from embryo to early pupa). Progressive degeneration of the optic lobe and the antennae is also observed, along with severe defects in phototaxis and negative geotaxis. Retinal sections show extensive vacuolization, disorganisation of ommatidial architecture, photoreceptor loss, and vesicular accumulations in the pigment cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Named alicorn (unicorn horn) for the 'horn' of semi-transparent deposit that accumulates over time on the antennae of adults whose eyes and antennae are homozygous for an 'alc' allele.