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Gene Dmel\mei-38

General Information
Symbol	Dmel\mei-38	Species	D. melanogaster
Name	meiotic 38	Annotation symbol	CG14781
Feature type	protein_coding_gene	FlyBase ID	FBgn0260986
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	2B1-2B1	Sequence location	X:1,371,127..1,372,515 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene meiotic 38 is referred to in FlyBase by the symbol Dmel\mei-38 (CG14781, FBgn0260986). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; reciprocal meiotic recombination; female meiosis; mitotic spindle elongation; distributive segregation; homologous chromosome segregation; mitotic spindle organization; meiotic spindle organization. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1640362_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mei-38. Gene sequence location is X:1371127..1372515.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN46169 HFA18564 BKN25547
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 2B1-2B1   Limits computationally determined from genome sequence between P{EP}futschEP1419 and P{EP}brEP1515
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mei-38 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mei-38-RA FBtr0070258  NM_130566   1302   325
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mei-38-PA   FBpp0070248   37.0   325   8.48     NP_569922   AAF45636
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263757   AA390428   AA696934   AA816545   AA941666   AA942053   AE014298 AAF45636   AI455958   AI515213   AL031027 CAB41537   AY089578 AAL90316   BG637735   BI169844   BI170226   BI239504   BI636759   BT044309   CO290848   CO291506   CO333827   EC200777   EC207883   EC228360   EC235421   EC240289   EV581329   EV589401   FD585620   FD585724   FD586017   FD587257   FD587326   FD587364
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8SXL0 Q9W584 Q9XZT3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0260986    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0260986 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0260986 expression level Developmental Stage   Expression Level embryo 00-02hr    7848 embryo 02-04hr    4413 embryo 04-06hr    4641 embryo 06-08hr    3623 embryo 08-10hr    2553 embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day    2788 adult female 30day    3270 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (7848) embryo 02-04hr  (4413) embryo 04-06hr  (4641) embryo 06-08hr  (3623) embryo 08-10hr  (2553) embryo 10-12hr  (1352) embryo 12-14hr  (626) embryo 14-16hr  (589) embryo 16-18hr  (342) embryo 18-20hr  (263) embryo 20-22hr  (283) embryo 22-24hr  (314) larva L1    62 larva L2  (112) larva L3 12hr old  (158) larva L3 puffstage 1-2  (346) larva L3 puffstage 3-6  (439) larva L3 puffstage 7-9  (454) white prepupae new  (395) white prepupae 12hr  (854) white prepupae 24hr  (562) pupae 2d postWPP  (233) pupae 3d postWPP  (110) pupae 4d postWPP  (214) adult male 01day    83 adult male 05day  (157) adult male 30day  (153) adult female 01day  (1232) adult female 05day  (2788) adult female 30day  (3270) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (7848) embryo 02-04hr  (4413) embryo 04-06hr  (4641) embryo 06-08hr  (3623) embryo 08-10hr  (2553) embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day  (2788) adult female 30day  (3270) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7848 embryo 02-04hr    4413 embryo 04-06hr    4641 embryo 06-08hr    3623 embryo 08-10hr    2553 embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day    2788 adult female 30day    3270 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7848 embryo 02-04hr    4413 embryo 04-06hr    4641 embryo 06-08hr    3623 embryo 08-10hr    2553 embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day    2788 adult female 30day    3270 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0260986 expression level Developmental Stage   Expression Level embryo 00-02hr    7848 embryo 02-04hr    4413 embryo 04-06hr    4641 embryo 06-08hr    3623 embryo 08-10hr    2553 embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day    2788 adult female 30day    3270 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (7848) embryo 02-04hr  (4413) embryo 04-06hr  (4641) embryo 06-08hr  (3623) embryo 08-10hr  (2553) embryo 10-12hr  (1352) embryo 12-14hr  (626) embryo 14-16hr  (589) embryo 16-18hr  (342) embryo 18-20hr  (263) embryo 20-22hr  (283) embryo 22-24hr  (314) larva L1    62 larva L2  112 larva L3 12hr old  (158) larva L3 puffstage 1-2  (346) larva L3 puffstage 3-6  (439) larva L3 puffstage 7-9  (454) white prepupae new  (395) white prepupae 12hr  (854) white prepupae 24hr  (562) pupae 2d postWPP  (233) pupae 3d postWPP  110 pupae 4d postWPP  (214) adult male 01day    83 adult male 05day  (157) adult male 30day  (153) adult female 01day  (1232) adult female 05day  (2788) adult female 30day  (3270) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (7848) embryo 02-04hr  (4413) embryo 04-06hr  (4641) embryo 06-08hr  (3623) embryo 08-10hr  (2553) embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day  (2788) adult female 30day  (3270) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    7848 embryo 02-04hr    4413 embryo 04-06hr    4641 embryo 06-08hr    3623 embryo 08-10hr    2553 embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day    2788 adult female 30day    3270 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    7848 embryo 02-04hr    4413 embryo 04-06hr    4641 embryo 06-08hr    3623 embryo 08-10hr    2553 embryo 10-12hr    1352 embryo 12-14hr    626 embryo 14-16hr    589 embryo 16-18hr    342 embryo 18-20hr    263 embryo 20-22hr    283 embryo 22-24hr    314 larva L1    62 larva L2    112 larva L3 12hr old    158 larva L3 puffstage 1-2    346 larva L3 puffstage 3-6    439 larva L3 puffstage 7-9    454 white prepupae new    395 white prepupae 12hr    854 white prepupae 24hr    562 pupae 2d postWPP    233 pupae 3d postWPP    110 pupae 4d postWPP    214 adult male 01day    83 adult male 05day    157 adult male 30day    153 adult female 01day    1232 adult female 05day    2788 adult female 30day    3270 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0260986    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0260986 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0260986 expression level Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0260986 expression level Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    81.625 Larval Midgut    1.8 Larval Hindgut    2.6 Larval Malpighian Tubules    8.8 Larval Fat Body    4.1 Larval Salivary Gland    1.4 Larval Trachea    23.8 Larval Carcass    3.675 Adult Head    0.7 Adult Eye    2.975 Adult Brain    2 Adult Thoracic-Abdominal Ganglion    1 Adult Crop    0.9 Adult Midgut    1.4 Adult Hindgut    1.4 Adult Malpighian Tubules    1.1 Adult Fat Body    1.4 Adult Salivary Gland    9.9 Adult Heart    3.05 Adult VirginFemale Spermatheca    1.7 Adult InseminatedFemale Spermatheca    1 Adult Ovary    188 Adult Testis no informative data Adult Male Accessory Gland    1.2 Adult Carcass    4.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis no informative data Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    0.7   NA  Eye    2.975   NA  Brain    2   81.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1   NA  Crop    0.9   1.8  Midgut    1.4   2.6  Hindgut    1.4   8.8  Malpighian Tubules    1.1   4.1  Fat Body    1.4   1.4  Salivary Gland    9.9   NA  Heart    3.05   23.8  Trachea    NA   NA  VirginFemale Spermatheca    1.7   NA  InseminatedFemale Spermatheca    1   NA  Ovary    188   NA  Testis    no informative data   NA  Male Accessory Gland    1.2   3.675  Carcass    4.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0260986
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele karyosome & oocyte mei-381 spindle microtubule & larval brain mei-381 spindle microtubule & oocyte mei-381 spindle pole & larval brain mei-381 spindle pole & oocyte mei-381
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of mei-38 Class Mutagen Stocks Known lesion mei-381 amorphic allele - genetic evidence 1 Yes mei-38G17201 P-element activity 1 -- mei-38J23 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mei-38 Class Mutagen Stocks Known lesion mei-38GD8439 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes mei-38MtnA.N.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes mei-38Scer\UAS.P\T.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6227 (Ryder, 2004.4.26, Wu et al., 2008) Df(1)S39 (Wu et al., 2008)
Not disrupted in	Df(1)Exel8196 (Wu et al., 2008) Df(1)FDD-0225927 (Wu et al., 2008, Wu et al., 2008)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{UASp-mei-38.HA} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{GT1}BG02601BG02601 NA insertion of mobile activating element P{EP}mei-38G17201 NA
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 12 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
distributive segregation inferred from genetic interaction with mei-218 (Wu et al., 2008) inferred from mutant phenotype (Wu et al., 2008) female meiosis inferred from mutant phenotype (Wu et al., 2008) female meiosis chromosome segregation inferred from mutant phenotype (Baker and Carpenter, 1972) homologous chromosome segregation inferred from mutant phenotype (Wu et al., 2008) meiotic spindle organization inferred from mutant phenotype (Wu et al., 2008) mitotic spindle elongation inferred from mutant phenotype (Goshima et al., 2007) mitotic spindle organization inferred from mutant phenotype (Wu et al., 2008) reciprocal meiotic recombination inferred from mutant phenotype (Baker and Carpenter, 1972)
Cellular Component
CV term Evidence References
kinetochore microtubule inferred from direct assay (Wu et al., 2008) polar microtubule inferred from direct assay (Wu et al., 2008) colocalizes_with spindle inferred from direct assay (Goshima et al., 2007) NOT spindle midzone inferred from direct assay (Wu et al., 2008)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mei-38 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0260986
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20913 Dere\GG12862 Dgri\GH17950 Dmoj\GI16488 Dper\GL14260 Dpse\GA22721 Dsec\GM19145 Dvir\GJ16033 Dwil\GK16093 Dyak\GE16693
Curated drosophilid orthologs	Dpse\GA13241
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL008088-PA Aedes aegypti (mosquito) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0234190 FBgn0218095 FBgn0203218 FBgn0174047 FBgn0244124 FBgn0151865 FBgn0139236 FBgn0125418 FBgn0105137 FBgn0097918
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	33298 P{EP}mei-38G17201 w* 4881 y1 mei-381/C(1)DX, y1 f1/Dp(1;Y)y+; svspa-pol
VDRC	v51805 w1118; P{GD8439}v51805 v51804 w1118; P{GD8439}v51804/CyO
Genomic Clones ( 1 )
	BACR09H15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 29 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE11134
Other clones	FI07204
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM08731 LD07037 LD08719 LD26064 LD27014 LD35696 LD46943 RE11617 RE35995 SD18572
Other clones	65265 70041 282451 CK01.2A.H12 CK01.97A.F8 Dmel_dig_017089_0656_2619 Dmel_neb_010785_0354_2699 EK075353 EK197527 EK308115 LD02045 RM03407 RM03607 RM03707 RM03807 RM04007 RM04107
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0260986 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31104 5657453
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: ssp1 CG14781 (Goshima et al., 2007)
Source for database merge of	Source for merge of: mei-38 ssp1 (Wu et al., 2008)
Additional comments
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene results in aberrantly short spindles when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130566 RefSeq (Proteins) • NP_569922 DDBJ / EMBL / GenBank • AA816545 AAF45636 AAL90316 AL031027 AY089578 BG637735 BI169844 CAB41537 Entrez Gene - A searchable database of RefSeq genes. • 31104 UniProtKB/TrEMBL • Q8SXL0 Q9W584 Q9XZT3
Other Crossreferences
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0260986 DRSC - Results from RNAi screens. • FBgn0260986 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0260986 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0260986 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31104 5657453 InParanoid A subset of ortholog calls from InParanoid. • AAEL008088-PA Aedes aegypti (mosquito) modMine - Data generated by the modENCODE project. • FBgn0260986 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0234190 FBgn0218095 FBgn0203218 FBgn0174047 FBgn0244124 FBgn0151865 FBgn0139236 FBgn0125418 FBgn0105137 FBgn0097918
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	CG14781 (Goshima et al., 2007, Sambandan et al., 2006, Somma et al., 2008, Wu et al., 2008, Sousa-Neves and Rosas, 2010) EG:80H7.11 (Benos et al., 2001, ) mei-38 (Baker and Carpenter, 1972, Wu et al., 2008, Sousa-Neves and Rosas, 2010) ssp1   Ssp1 (Goshima et al., 2007)
Name Synonym	CG14781 (Somma et al., 2008) mei-38   meiotic 38   short spindle 1
Secondary FlyBase IDs
	FBgn0016035 FBgn0026871
References ( 16 )
Research paper	Sousa-Neves and Rosas, 2010, PLoS ONE 5(5): e10485 An analysis of genetic changes during the divergence of Drosophila species. [FBrf0210766] Somma et al., 2008, PLoS Genet. 4(7): e1000126 Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. [FBrf0206064] Wu et al., 2008, Genetics 180(1): 61--72 mei-38 is required for chromosome segregation during meiosis in Drosophila females. [FBrf0206885] Sambandan et al., 2006, Genetics 174(3): 1349--1363 Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. [FBrf0192106] Benos et al., 2001, Genome Res. 11(5): 710--730 From First Base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies. [FBrf0135823] Baker and Carpenter, 1972, Genetics 71: 255--286 Genetic analysis of sex chromosomal meiotic mutants in Drosophila melanogaster. [FBrf0023919]
Supplementary material	Goshima et al., 2007, Science 316(5823): Supporting online material for Genes required for mitotic spindle assembly in Drosophila S2 cells. [FBrf0200397]
Review	McKim et al., 2002, A. Rev. Genet. 36: 205--232 Meiotic recombination and chromosome segregation in Drosophila females. [FBrf0151729] Hawley et al., 1993, A. Rev. Genet. 27: 281--317 Meiotic segregation in Drosophila melanogaster females: molecules, mechanisms, and myths. [FBrf0068520]
Personal communication to FlyBase	Bellen, 2010.12.22, GE836.xml GE836.xml [FBrf0212684] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Benos, 2000.12.13, FlyBase error report on Wed Dec 13 14:35:56 2000. FlyBase error report on Wed Dec 13 14:35:56 2000. [FBrf0133222] Carpenter, 1998.11.24, Info on Adelaide Carpenter's stocks. Info on Adelaide Carpenter's stocks. [FBrf0106081]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]