Gene model reviewed during 5.49
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\clos using the Feature Mapper tool.
clos protein is first detected in early egg chambers in the presumptive oocyte. As egg chambers matured, it became stronger and was found at the periphery of the oocyte. Staining was observed in a finger-like pattern associated with microvilli formed by the oocyte plasma membrane.
GBrowse - Visual display of RNA-Seq signalsView Dmel\clos in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: clos CG42600
Annotations CG12928 and CG34364 merged as CG42600 in release 5.19 of the genome annotation.
FlyBase curator comment: Correspondence with author Ventura revealed that 'closca' corresponds to CG34364 and CG12928.
Annotations CG12927, CG1863 and CG33479 merged as CG34364 in release 5.2 of the genome annotation.
The gene is named "closca", the Catalan word for "eggshell" since mutant females lay eggs that collapse after deposition.