p52, Tfb2, Dmp52, marionnette, nc16
Gene model reviewed during 5.45
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mrn using the Feature Mapper tool.
Maternally deposited mrn transcripts are observed in early embryos. In later embryos, expression is highest in proliferating cells of the nervous system, Malpighian tubules and midgut. During larval stages, mrn transcripts are observed in restricted regions of the imaginal discs and are especially high in the wing pouch region of the wing disc and in the morphogenetic furrow in the eye disc.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mrn in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Tfb2 CG7764
Source for merge of Tfb2 anon-WO0118547.648 was sequence comparison ( date:051113 ).
Recessive larval lethal. Individuals heterozygous for certain combinations of alleles reach late third instar but do not pupate; they have small discs and small brains. The original allele nc16, is associated with a dominant enhancer of the βTub85Dn -tubulin mutation, suggesting a role for the gene in microtubule function. The dominant enhancer and the lethal mutation associated with nc16 were not separated in 82 recombinants between Ly and th. None of the other alleles are dominant enhancers of βTub85Dn (Robertson and Fuller, unpublished).