General Information Symbol Dmel\ Xrp1Species D. melanogaster Name Annotation symbol CG17836 Feature type protein_coding_gene FlyBase ID FBgn0261113 Gene Model Status Current Stock availability 15 publicly
available Genomic Location Chromosome (arm) 3R Recombination map Cytogenetic map 91D3-91D5 Sequence location 3R:14,740,690..14,752,711 [+]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\Xrp1 (CG17836, FBgn0261113). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : protein dimerization activity. There is experimental evidence that it is involved in the
biological process : olfactory behavior; cellular process; chromosome organization; imaginal disc-derived wing morphogenesis; negative regulation of cell proliferation.
27 alleles are reported . The
phenotype of these alleles is annotated with: wing. It has
7 annotated transcripts and
7 annotated polypeptides .
Protein features are: AT hook, DNA-binding motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1632712_s_at completely aligns to an exonic region common to each of the 5 FlyBase-annotated transcript isoforms of Xrp1. Gene sequence location is
3R:14740690..14752711 .
User Contributed Data
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
91D3-91D5
(determined by in situ hybridisation)
91D3-91D5
(determined by in situ hybridisation)
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.47
Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: reported as anal pad specific anlage
Comment: reported as posterior spiracle specific anlage
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
1395.3
Larval Hindgut
1290.9
Larval Malpighian Tubules
2096.5
Larval Fat Body
718.4
Larval Salivary Gland
880.7
Larval Trachea
1692.75
Larval Carcass
1173.45
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
918.8
Adult Crop
1047.6
Adult Midgut
1682
Adult Hindgut
1151.8
Adult Malpighian Tubules
2995.2
Adult Fat Body
888
Adult Salivary Gland
889.5
Adult Heart
1334.375
Adult VirginFemale Spermatheca
1080.7
Adult InseminatedFemale Spermatheca
1099.4
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
1178.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
(1395.3)
Larval Hindgut
(1290.9)
Larval Malpighian Tubules
(2096.5)
Larval Fat Body
(718.4)
Larval Salivary Gland
(880.7)
Larval Trachea
(1692.75)
Larval Carcass
(1173.45)
Adult Head
(798.1)
Adult Eye
(654.7)
Adult Brain
(694.4)
Adult Thoracic-Abdominal Ganglion
(918.8)
Adult Crop
(1047.6)
Adult Midgut
(1682)
Adult Hindgut
(1151.8)
Adult Malpighian Tubules
(2995.2)
Adult Fat Body
(888)
Adult Salivary Gland
(889.5)
Adult Heart
(1334.375)
Adult VirginFemale Spermatheca
(1080.7)
Adult InseminatedFemale Spermatheca
(1099.4)
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
(617.8)
Adult Carcass
(1178.9)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
(1395.3)
Larval Hindgut
(1290.9)
Larval Malpighian Tubules
(2096.5)
Larval Fat Body
718.4
Larval Salivary Gland
880.7
Larval Trachea
(1692.75)
Larval Carcass
(1173.45)
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
918.8
Adult Crop
1047.6
Adult Midgut
(1682)
Adult Hindgut
(1151.8)
Adult Malpighian Tubules
(2995.2)
Adult Fat Body
888
Adult Salivary Gland
889.5
Adult Heart
(1334.375)
Adult VirginFemale Spermatheca
(1080.7)
Adult InseminatedFemale Spermatheca
(1099.4)
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
(1178.9)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
1395.3
Larval Hindgut
1290.9
Larval Malpighian Tubules
2096.5
Larval Fat Body
718.4
Larval Salivary Gland
880.7
Larval Trachea
1692.75
Larval Carcass
1173.45
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
918.8
Adult Crop
1047.6
Adult Midgut
1682
Adult Hindgut
1151.8
Adult Malpighian Tubules
2995.2
Adult Fat Body
888
Adult Salivary Gland
889.5
Adult Heart
1334.375
Adult VirginFemale Spermatheca
1080.7
Adult InseminatedFemale Spermatheca
1099.4
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
1178.9
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
1395.3
Larval Hindgut
1290.9
Larval Malpighian Tubules
2096.5
Larval Fat Body
718.4
Larval Salivary Gland
880.7
Larval Trachea
1692.75
Larval Carcass
1173.45
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
918.8
Adult Crop
1047.6
Adult Midgut
1682
Adult Hindgut
1151.8
Adult Malpighian Tubules
2995.2
Adult Fat Body
888
Adult Salivary Gland
889.5
Adult Heart
1334.375
Adult VirginFemale Spermatheca
1080.7
Adult InseminatedFemale Spermatheca
1099.4
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
1178.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
(1395.3)
Larval Hindgut
(1290.9)
Larval Malpighian Tubules
(2096.5)
Larval Fat Body
718.4
Larval Salivary Gland
(880.7)
Larval Trachea
(1692.75)
Larval Carcass
(1173.45)
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
(918.8)
Adult Crop
(1047.6)
Adult Midgut
(1682)
Adult Hindgut
(1151.8)
Adult Malpighian Tubules
(2995.2)
Adult Fat Body
(888)
Adult Salivary Gland
(889.5)
Adult Heart
(1334.375)
Adult VirginFemale Spermatheca
(1080.7)
Adult InseminatedFemale Spermatheca
(1099.4)
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
(1178.9)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
1395.3
Larval Hindgut
1290.9
Larval Malpighian Tubules
(2096.5)
Larval Fat Body
718.4
Larval Salivary Gland
880.7
Larval Trachea
1692.75
Larval Carcass
1173.45
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
918.8
Adult Crop
1047.6
Adult Midgut
1682
Adult Hindgut
1151.8
Adult Malpighian Tubules
(2995.2)
Adult Fat Body
888
Adult Salivary Gland
889.5
Adult Heart
1334.375
Adult VirginFemale Spermatheca
1080.7
Adult InseminatedFemale Spermatheca
1099.4
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
1178.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
530.35
Larval Midgut
1395.3
Larval Hindgut
1290.9
Larval Malpighian Tubules
2096.5
Larval Fat Body
718.4
Larval Salivary Gland
880.7
Larval Trachea
1692.75
Larval Carcass
1173.45
Adult Head
798.1
Adult Eye
654.7
Adult Brain
694.4
Adult Thoracic-Abdominal Ganglion
918.8
Adult Crop
1047.6
Adult Midgut
1682
Adult Hindgut
1151.8
Adult Malpighian Tubules
2995.2
Adult Fat Body
888
Adult Salivary Gland
889.5
Adult Heart
1334.375
Adult VirginFemale Spermatheca
1080.7
Adult InseminatedFemale Spermatheca
1099.4
Adult Ovary
79.4
Adult Testis
107.8
Adult Male Accessory Gland
617.8
Adult Carcass
1178.9
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
798.1
NA
Eye
654.7
NA
Brain
694.4
530.35
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
918.8
NA
Crop
1047.6
1395.3
Midgut
1682
1290.9
Hindgut
1151.8
2096.5
Malpighian Tubules
2995.2
718.4
Fat Body
888
880.7
Salivary Gland
889.5
NA
Heart
1334.375
1692.75
Trachea
NA
NA
VirginFemale Spermatheca
1080.7
NA
InseminatedFemale Spermatheca
1099.4
NA
Ovary
79.4
NA
Testis
107.8
NA
Male Accessory Gland
617.8
1173.45
Carcass
1178.9
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
168
central nervous system, larvae L3
119
central nervous system, pupae P8
69
head, virgin 1-day female
162
head, virgin 4-day female
173
head, virgin 20-day female
140
head, mated 1-day female
202
head, mated 4-day female
160
head, mated 20-day female
160
head, mated 1-day male
226
head, mated 4-day male
238
head, mated 20-day male
310
salivary gland, larvae L3 wandering
45
salivary gland, white prepupae
114
digestive system, larvae L3 wandering
255
digestive system, 1-day adult
415
digestive system, 4-day adult
578
digestive system, 20-day adult
457
fat body, larvae L3 wandering
450
fat body, white prepupae
352
fat body, pupae P8
120
carcass, larvae L3 wandering
196
carcass, 1-day adult
284
carcass, 4-day adult
305
carcass, 20-day adult
279
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
80
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(168)
central nervous system, larvae L3
(119)
central nervous system, pupae P8
(69)
head, virgin 1-day female
(162)
head, virgin 4-day female
(173)
head, virgin 20-day female
(140)
head, mated 1-day female
(202)
head, mated 4-day female
(160)
head, mated 20-day female
(160)
head, mated 1-day male
(226)
head, mated 4-day male
(238)
head, mated 20-day male
(310)
salivary gland, larvae L3 wandering
(45)
salivary gland, white prepupae
(114)
digestive system, larvae L3 wandering
(255)
digestive system, 1-day adult
(415)
digestive system, 4-day adult
(578)
digestive system, 20-day adult
(457)
fat body, larvae L3 wandering
(450)
fat body, white prepupae
(352)
fat body, pupae P8
(120)
carcass, larvae L3 wandering
(196)
carcass, 1-day adult
(284)
carcass, 4-day adult
(305)
carcass, 20-day adult
(279)
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
(28)
accessory gland, mated 4-day male
(80)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(168)
central nervous system, larvae L3
(119)
central nervous system, pupae P8
69
head, virgin 1-day female
(162)
head, virgin 4-day female
(173)
head, virgin 20-day female
(140)
head, mated 1-day female
(202)
head, mated 4-day female
(160)
head, mated 20-day female
(160)
head, mated 1-day male
(226)
head, mated 4-day male
(238)
head, mated 20-day male
(310)
salivary gland, larvae L3 wandering
45
salivary gland, white prepupae
(114)
digestive system, larvae L3 wandering
(255)
digestive system, 1-day adult
(415)
digestive system, 4-day adult
(578)
digestive system, 20-day adult
(457)
fat body, larvae L3 wandering
(450)
fat body, white prepupae
(352)
fat body, pupae P8
(120)
carcass, larvae L3 wandering
(196)
carcass, 1-day adult
(284)
carcass, 4-day adult
(305)
carcass, 20-day adult
(279)
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
80
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
168
central nervous system, larvae L3
119
central nervous system, pupae P8
69
head, virgin 1-day female
162
head, virgin 4-day female
173
head, virgin 20-day female
140
head, mated 1-day female
202
head, mated 4-day female
160
head, mated 20-day female
160
head, mated 1-day male
226
head, mated 4-day male
238
head, mated 20-day male
310
salivary gland, larvae L3 wandering
45
salivary gland, white prepupae
114
digestive system, larvae L3 wandering
255
digestive system, 1-day adult
415
digestive system, 4-day adult
578
digestive system, 20-day adult
457
fat body, larvae L3 wandering
450
fat body, white prepupae
352
fat body, pupae P8
120
carcass, larvae L3 wandering
196
carcass, 1-day adult
284
carcass, 4-day adult
305
carcass, 20-day adult
279
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
80
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
168
central nervous system, larvae L3
119
central nervous system, pupae P8
69
head, virgin 1-day female
162
head, virgin 4-day female
173
head, virgin 20-day female
140
head, mated 1-day female
202
head, mated 4-day female
160
head, mated 20-day female
160
head, mated 1-day male
226
head, mated 4-day male
238
head, mated 20-day male
310
salivary gland, larvae L3 wandering
45
salivary gland, white prepupae
114
digestive system, larvae L3 wandering
255
digestive system, 1-day adult
415
digestive system, 4-day adult
578
digestive system, 20-day adult
457
fat body, larvae L3 wandering
450
fat body, white prepupae
352
fat body, pupae P8
120
carcass, larvae L3 wandering
196
carcass, 1-day adult
284
carcass, 4-day adult
305
carcass, 20-day adult
279
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
80
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(168)
central nervous system, larvae L3
(119)
central nervous system, pupae P8
(69)
head, virgin 1-day female
(162)
head, virgin 4-day female
(173)
head, virgin 20-day female
(140)
head, mated 1-day female
(202)
head, mated 4-day female
(160)
head, mated 20-day female
(160)
head, mated 1-day male
(226)
head, mated 4-day male
(238)
head, mated 20-day male
(310)
salivary gland, larvae L3 wandering
(45)
salivary gland, white prepupae
(114)
digestive system, larvae L3 wandering
(255)
digestive system, 1-day adult
(415)
digestive system, 4-day adult
(578)
digestive system, 20-day adult
(457)
fat body, larvae L3 wandering
(450)
fat body, white prepupae
(352)
fat body, pupae P8
(120)
carcass, larvae L3 wandering
(196)
carcass, 1-day adult
(284)
carcass, 4-day adult
(305)
carcass, 20-day adult
(279)
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
(80)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(168)
central nervous system, larvae L3
119
central nervous system, pupae P8
69
head, virgin 1-day female
(162)
head, virgin 4-day female
(173)
head, virgin 20-day female
140
head, mated 1-day female
(202)
head, mated 4-day female
(160)
head, mated 20-day female
(160)
head, mated 1-day male
(226)
head, mated 4-day male
(238)
head, mated 20-day male
(310)
salivary gland, larvae L3 wandering
45
salivary gland, white prepupae
114
digestive system, larvae L3 wandering
(255)
digestive system, 1-day adult
(415)
digestive system, 4-day adult
(578)
digestive system, 20-day adult
(457)
fat body, larvae L3 wandering
(450)
fat body, white prepupae
(352)
fat body, pupae P8
120
carcass, larvae L3 wandering
(196)
carcass, 1-day adult
(284)
carcass, 4-day adult
(305)
carcass, 20-day adult
(279)
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
80
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
168
central nervous system, larvae L3
119
central nervous system, pupae P8
69
head, virgin 1-day female
162
head, virgin 4-day female
173
head, virgin 20-day female
140
head, mated 1-day female
202
head, mated 4-day female
160
head, mated 20-day female
160
head, mated 1-day male
226
head, mated 4-day male
238
head, mated 20-day male
310
salivary gland, larvae L3 wandering
45
salivary gland, white prepupae
114
digestive system, larvae L3 wandering
255
digestive system, 1-day adult
415
digestive system, 4-day adult
578
digestive system, 20-day adult
457
fat body, larvae L3 wandering
450
fat body, white prepupae
352
fat body, pupae P8
120
carcass, larvae L3 wandering
196
carcass, 1-day adult
284
carcass, 4-day adult
305
carcass, 20-day adult
279
ovary, virgin 4-day female
15
ovary, mated 4-day female
24
testis, mated 4-day male
28
accessory gland, mated 4-day male
80
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
36
embryo 12-14hr
48
embryo 14-16hr
60
embryo 16-18hr
83
embryo 18-20hr
114
embryo 20-22hr
181
embryo 22-24hr
187
larva L1
105
larva L2
94
larva L3 12hr old
100
larva L3 puffstage 1-2
82
larva L3 puffstage 3-6
90
larva L3 puffstage 7-9
72
white prepupae new
89
white prepupae 12hr
74
white prepupae 24hr
78
pupae 2d postWPP
66
pupae 3d postWPP
45
pupae 4d postWPP
49
adult male 01day
88
adult male 05day
98
adult male 30day
117
adult female 01day
63
adult female 05day
30
adult female 30day
37
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
(36)
embryo 12-14hr
(48)
embryo 14-16hr
(60)
embryo 16-18hr
(83)
embryo 18-20hr
(114)
embryo 20-22hr
(181)
embryo 22-24hr
(187)
larva L1
(105)
larva L2
(94)
larva L3 12hr old
(100)
larva L3 puffstage 1-2
(82)
larva L3 puffstage 3-6
(90)
larva L3 puffstage 7-9
(72)
white prepupae new
(89)
white prepupae 12hr
(74)
white prepupae 24hr
(78)
pupae 2d postWPP
(66)
pupae 3d postWPP
(45)
pupae 4d postWPP
(49)
adult male 01day
(88)
adult male 05day
(98)
adult male 30day
(117)
adult female 01day
(63)
adult female 05day
(30)
adult female 30day
(37)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
36
embryo 12-14hr
48
embryo 14-16hr
60
embryo 16-18hr
83
embryo 18-20hr
(114)
embryo 20-22hr
(181)
embryo 22-24hr
(187)
larva L1
105
larva L2
94
larva L3 12hr old
100
larva L3 puffstage 1-2
82
larva L3 puffstage 3-6
90
larva L3 puffstage 7-9
72
white prepupae new
89
white prepupae 12hr
74
white prepupae 24hr
78
pupae 2d postWPP
66
pupae 3d postWPP
45
pupae 4d postWPP
49
adult male 01day
88
adult male 05day
98
adult male 30day
(117)
adult female 01day
63
adult female 05day
30
adult female 30day
37
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
36
embryo 12-14hr
48
embryo 14-16hr
60
embryo 16-18hr
83
embryo 18-20hr
114
embryo 20-22hr
181
embryo 22-24hr
187
larva L1
105
larva L2
94
larva L3 12hr old
100
larva L3 puffstage 1-2
82
larva L3 puffstage 3-6
90
larva L3 puffstage 7-9
72
white prepupae new
89
white prepupae 12hr
74
white prepupae 24hr
78
pupae 2d postWPP
66
pupae 3d postWPP
45
pupae 4d postWPP
49
adult male 01day
88
adult male 05day
98
adult male 30day
117
adult female 01day
63
adult female 05day
30
adult female 30day
37
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
36
embryo 12-14hr
48
embryo 14-16hr
60
embryo 16-18hr
83
embryo 18-20hr
114
embryo 20-22hr
181
embryo 22-24hr
187
larva L1
105
larva L2
94
larva L3 12hr old
100
larva L3 puffstage 1-2
82
larva L3 puffstage 3-6
90
larva L3 puffstage 7-9
72
white prepupae new
89
white prepupae 12hr
74
white prepupae 24hr
78
pupae 2d postWPP
66
pupae 3d postWPP
45
pupae 4d postWPP
49
adult male 01day
88
adult male 05day
98
adult male 30day
117
adult female 01day
63
adult female 05day
30
adult female 30day
37
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
(36)
embryo 12-14hr
(48)
embryo 14-16hr
(60)
embryo 16-18hr
(83)
embryo 18-20hr
(114)
embryo 20-22hr
(181)
embryo 22-24hr
(187)
larva L1
(105)
larva L2
(94)
larva L3 12hr old
(100)
larva L3 puffstage 1-2
(82)
larva L3 puffstage 3-6
(90)
larva L3 puffstage 7-9
(72)
white prepupae new
(89)
white prepupae 12hr
(74)
white prepupae 24hr
(78)
pupae 2d postWPP
(66)
pupae 3d postWPP
(45)
pupae 4d postWPP
(49)
adult male 01day
(88)
adult male 05day
(98)
adult male 30day
(117)
adult female 01day
(63)
adult female 05day
30
adult female 30day
(37)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
36
embryo 12-14hr
48
embryo 14-16hr
60
embryo 16-18hr
83
embryo 18-20hr
114
embryo 20-22hr
(181)
embryo 22-24hr
(187)
larva L1
105
larva L2
94
larva L3 12hr old
100
larva L3 puffstage 1-2
82
larva L3 puffstage 3-6
90
larva L3 puffstage 7-9
72
white prepupae new
89
white prepupae 12hr
74
white prepupae 24hr
78
pupae 2d postWPP
66
pupae 3d postWPP
45
pupae 4d postWPP
49
adult male 01day
88
adult male 05day
98
adult male 30day
117
adult female 01day
63
adult female 05day
30
adult female 30day
37
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
1
embryo 02-04hr
2
embryo 04-06hr
2
embryo 06-08hr
7
embryo 08-10hr
14
embryo 10-12hr
36
embryo 12-14hr
48
embryo 14-16hr
60
embryo 16-18hr
83
embryo 18-20hr
114
embryo 20-22hr
181
embryo 22-24hr
187
larva L1
105
larva L2
94
larva L3 12hr old
100
larva L3 puffstage 1-2
82
larva L3 puffstage 3-6
90
larva L3 puffstage 7-9
72
white prepupae new
89
white prepupae 12hr
74
white prepupae 24hr
78
pupae 2d postWPP
66
pupae 3d postWPP
45
pupae 4d postWPP
49
adult male 01day
88
adult male 05day
98
adult male 30day
117
adult female 01day
63
adult female 05day
30
adult female 30day
37
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
426
Schneider line 2 Sg4
206
embryonic 1182-4H
788
embryonic GM2
754
embryonic Kc167
383
embryonic S1
813
embryonic S3
208
leg disc CME L1
615
wing disc CME-W2
349
wing disc ML-DmD8
530
wing disc ML-DmD9
870
wing disc ML-DmD16-c3
737
wing disc ML-DmD21
229
wing disc ML-DmD32
1062
haltere disc ML-DmD17-c3
183
eye-antennal disc ML-DmD11
486
antennal disc ML-DmD20-c5
241
mixed discs ML-DmD4-c1
646
CNS ML-DmBG1-c1
251
CNS ML-DmBG2-c2
336
tumorous blood cells mbn2
602
ovary fGS/OSS
612
ovary OSC
1607
ovary OSS
870
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(426)
Schneider line 2 Sg4
(206)
embryonic 1182-4H
(788)
embryonic GM2
(754)
embryonic Kc167
(383)
embryonic S1
(813)
embryonic S3
(208)
leg disc CME L1
(615)
wing disc CME-W2
(349)
wing disc ML-DmD8
(530)
wing disc ML-DmD9
(870)
wing disc ML-DmD16-c3
(737)
wing disc ML-DmD21
(229)
wing disc ML-DmD32
(1062)
haltere disc ML-DmD17-c3
(183)
eye-antennal disc ML-DmD11
(486)
antennal disc ML-DmD20-c5
(241)
mixed discs ML-DmD4-c1
(646)
CNS ML-DmBG1-c1
(251)
CNS ML-DmBG2-c2
(336)
tumorous blood cells mbn2
(602)
ovary fGS/OSS
(612)
ovary OSC
(1607)
ovary OSS
(870)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(426)
Schneider line 2 Sg4
(206)
embryonic 1182-4H
(788)
embryonic GM2
(754)
embryonic Kc167
(383)
embryonic S1
(813)
embryonic S3
(208)
leg disc CME L1
(615)
wing disc CME-W2
(349)
wing disc ML-DmD8
(530)
wing disc ML-DmD9
(870)
wing disc ML-DmD16-c3
(737)
wing disc ML-DmD21
(229)
wing disc ML-DmD32
(1062)
haltere disc ML-DmD17-c3
(183)
eye-antennal disc ML-DmD11
(486)
antennal disc ML-DmD20-c5
(241)
mixed discs ML-DmD4-c1
(646)
CNS ML-DmBG1-c1
(251)
CNS ML-DmBG2-c2
(336)
tumorous blood cells mbn2
(602)
ovary fGS/OSS
(612)
ovary OSC
(1607)
ovary OSS
(870)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
426
Schneider line 2 Sg4
206
embryonic 1182-4H
788
embryonic GM2
754
embryonic Kc167
383
embryonic S1
813
embryonic S3
208
leg disc CME L1
615
wing disc CME-W2
349
wing disc ML-DmD8
530
wing disc ML-DmD9
870
wing disc ML-DmD16-c3
737
wing disc ML-DmD21
229
wing disc ML-DmD32
1062
haltere disc ML-DmD17-c3
183
eye-antennal disc ML-DmD11
486
antennal disc ML-DmD20-c5
241
mixed discs ML-DmD4-c1
646
CNS ML-DmBG1-c1
251
CNS ML-DmBG2-c2
336
tumorous blood cells mbn2
602
ovary fGS/OSS
612
ovary OSC
1607
ovary OSS
870
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
426
Schneider line 2 Sg4
206
embryonic 1182-4H
788
embryonic GM2
754
embryonic Kc167
383
embryonic S1
813
embryonic S3
208
leg disc CME L1
615
wing disc CME-W2
349
wing disc ML-DmD8
530
wing disc ML-DmD9
870
wing disc ML-DmD16-c3
737
wing disc ML-DmD21
229
wing disc ML-DmD32
1062
haltere disc ML-DmD17-c3
183
eye-antennal disc ML-DmD11
486
antennal disc ML-DmD20-c5
241
mixed discs ML-DmD4-c1
646
CNS ML-DmBG1-c1
251
CNS ML-DmBG2-c2
336
tumorous blood cells mbn2
602
ovary fGS/OSS
612
ovary OSC
1607
ovary OSS
870
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(426)
Schneider line 2 Sg4
(206)
embryonic 1182-4H
(788)
embryonic GM2
(754)
embryonic Kc167
(383)
embryonic S1
(813)
embryonic S3
(208)
leg disc CME L1
(615)
wing disc CME-W2
(349)
wing disc ML-DmD8
(530)
wing disc ML-DmD9
(870)
wing disc ML-DmD16-c3
(737)
wing disc ML-DmD21
(229)
wing disc ML-DmD32
(1062)
haltere disc ML-DmD17-c3
(183)
eye-antennal disc ML-DmD11
(486)
antennal disc ML-DmD20-c5
(241)
mixed discs ML-DmD4-c1
(646)
CNS ML-DmBG1-c1
(251)
CNS ML-DmBG2-c2
(336)
tumorous blood cells mbn2
(602)
ovary fGS/OSS
(612)
ovary OSC
(1607)
ovary OSS
(870)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(426)
Schneider line 2 Sg4
(206)
embryonic 1182-4H
(788)
embryonic GM2
(754)
embryonic Kc167
(383)
embryonic S1
(813)
embryonic S3
(208)
leg disc CME L1
(615)
wing disc CME-W2
(349)
wing disc ML-DmD8
(530)
wing disc ML-DmD9
(870)
wing disc ML-DmD16-c3
(737)
wing disc ML-DmD21
(229)
wing disc ML-DmD32
(1062)
haltere disc ML-DmD17-c3
(183)
eye-antennal disc ML-DmD11
(486)
antennal disc ML-DmD20-c5
(241)
mixed discs ML-DmD4-c1
(646)
CNS ML-DmBG1-c1
(251)
CNS ML-DmBG2-c2
(336)
tumorous blood cells mbn2
(602)
ovary fGS/OSS
(612)
ovary OSC
(1607)
ovary OSS
(870)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
426
Schneider line 2 Sg4
206
embryonic 1182-4H
788
embryonic GM2
754
embryonic Kc167
383
embryonic S1
813
embryonic S3
208
leg disc CME L1
615
wing disc CME-W2
349
wing disc ML-DmD8
530
wing disc ML-DmD9
870
wing disc ML-DmD16-c3
737
wing disc ML-DmD21
229
wing disc ML-DmD32
1062
haltere disc ML-DmD17-c3
183
eye-antennal disc ML-DmD11
486
antennal disc ML-DmD20-c5
241
mixed discs ML-DmD4-c1
646
CNS ML-DmBG1-c1
251
CNS ML-DmBG2-c2
336
tumorous blood cells mbn2
602
ovary fGS/OSS
612
ovary OSC
1607
ovary OSS
870
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
229
cold shock, 4-day adult
180
heat shock, 4-day adult
167
Cadmium 50 mM 6 hrs, larvae L3
166
Cadmium 50 mM 12 hrs, larvae L3
131
Cadmium 50 mM 48 hrs, 4-day adult
318
Cadmium 100 mM 48 hrs, 4-day adult
411
Copper 0.5 mM 12 hrs, larvae L3
309
Copper 15 mM 48 hrs, 4-day adult
352
Zinc 5 mM 12 hrs, larvae L3
339
Zinc 4.5 mM 48 hrs, 4-day adult
407
Ethanol 2.5% 3 hrs, larvae L3
182
Ethanol 5% 3 hrs, larvae L3
269
Ethanol 10% 3 hrs, larvae L3
216
Caffeine 1.5 mg/ml 4 hrs, larvae L3
400
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
527
Caffeine 25 mg/ml 48 hrs, 4-day adult
304
Paraquat 5 mM 48 hrs, 4-day adult
244
Paraquat 10 mM 48 hrs, 4-day adult
439
Rotenone 2 μg 12 hrs, larvae L3
124
Rotenone 8 μg 12 hrs, larvae L3
136
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(229)
cold shock, 4-day adult
(180)
heat shock, 4-day adult
(167)
Cadmium 50 mM 6 hrs, larvae L3
(166)
Cadmium 50 mM 12 hrs, larvae L3
(131)
Cadmium 50 mM 48 hrs, 4-day adult
(318)
Cadmium 100 mM 48 hrs, 4-day adult
(411)
Copper 0.5 mM 12 hrs, larvae L3
(309)
Copper 15 mM 48 hrs, 4-day adult
(352)
Zinc 5 mM 12 hrs, larvae L3
(339)
Zinc 4.5 mM 48 hrs, 4-day adult
(407)
Ethanol 2.5% 3 hrs, larvae L3
(182)
Ethanol 5% 3 hrs, larvae L3
(269)
Ethanol 10% 3 hrs, larvae L3
(216)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(400)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(527)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(304)
Paraquat 5 mM 48 hrs, 4-day adult
(244)
Paraquat 10 mM 48 hrs, 4-day adult
(439)
Rotenone 2 μg 12 hrs, larvae L3
(124)
Rotenone 8 μg 12 hrs, larvae L3
(136)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
(229)
cold shock, 4-day adult
(180)
heat shock, 4-day adult
(167)
Cadmium 50 mM 6 hrs, larvae L3
(166)
Cadmium 50 mM 12 hrs, larvae L3
(131)
Cadmium 50 mM 48 hrs, 4-day adult
(318)
Cadmium 100 mM 48 hrs, 4-day adult
(411)
Copper 0.5 mM 12 hrs, larvae L3
(309)
Copper 15 mM 48 hrs, 4-day adult
(352)
Zinc 5 mM 12 hrs, larvae L3
(339)
Zinc 4.5 mM 48 hrs, 4-day adult
(407)
Ethanol 2.5% 3 hrs, larvae L3
(182)
Ethanol 5% 3 hrs, larvae L3
(269)
Ethanol 10% 3 hrs, larvae L3
(216)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(400)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(527)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(304)
Paraquat 5 mM 48 hrs, 4-day adult
(244)
Paraquat 10 mM 48 hrs, 4-day adult
(439)
Rotenone 2 μg 12 hrs, larvae L3
(124)
Rotenone 8 μg 12 hrs, larvae L3
(136)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
229
cold shock, 4-day adult
180
heat shock, 4-day adult
167
Cadmium 50 mM 6 hrs, larvae L3
166
Cadmium 50 mM 12 hrs, larvae L3
131
Cadmium 50 mM 48 hrs, 4-day adult
318
Cadmium 100 mM 48 hrs, 4-day adult
411
Copper 0.5 mM 12 hrs, larvae L3
309
Copper 15 mM 48 hrs, 4-day adult
352
Zinc 5 mM 12 hrs, larvae L3
339
Zinc 4.5 mM 48 hrs, 4-day adult
407
Ethanol 2.5% 3 hrs, larvae L3
182
Ethanol 5% 3 hrs, larvae L3
269
Ethanol 10% 3 hrs, larvae L3
216
Caffeine 1.5 mg/ml 4 hrs, larvae L3
400
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
527
Caffeine 25 mg/ml 48 hrs, 4-day adult
304
Paraquat 5 mM 48 hrs, 4-day adult
244
Paraquat 10 mM 48 hrs, 4-day adult
439
Rotenone 2 μg 12 hrs, larvae L3
124
Rotenone 8 μg 12 hrs, larvae L3
136
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
229
cold shock, 4-day adult
180
heat shock, 4-day adult
167
Cadmium 50 mM 6 hrs, larvae L3
166
Cadmium 50 mM 12 hrs, larvae L3
131
Cadmium 50 mM 48 hrs, 4-day adult
318
Cadmium 100 mM 48 hrs, 4-day adult
411
Copper 0.5 mM 12 hrs, larvae L3
309
Copper 15 mM 48 hrs, 4-day adult
352
Zinc 5 mM 12 hrs, larvae L3
339
Zinc 4.5 mM 48 hrs, 4-day adult
407
Ethanol 2.5% 3 hrs, larvae L3
182
Ethanol 5% 3 hrs, larvae L3
269
Ethanol 10% 3 hrs, larvae L3
216
Caffeine 1.5 mg/ml 4 hrs, larvae L3
400
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
527
Caffeine 25 mg/ml 48 hrs, 4-day adult
304
Paraquat 5 mM 48 hrs, 4-day adult
244
Paraquat 10 mM 48 hrs, 4-day adult
439
Rotenone 2 μg 12 hrs, larvae L3
124
Rotenone 8 μg 12 hrs, larvae L3
136
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
(229)
cold shock, 4-day adult
(180)
heat shock, 4-day adult
(167)
Cadmium 50 mM 6 hrs, larvae L3
(166)
Cadmium 50 mM 12 hrs, larvae L3
(131)
Cadmium 50 mM 48 hrs, 4-day adult
(318)
Cadmium 100 mM 48 hrs, 4-day adult
(411)
Copper 0.5 mM 12 hrs, larvae L3
(309)
Copper 15 mM 48 hrs, 4-day adult
(352)
Zinc 5 mM 12 hrs, larvae L3
(339)
Zinc 4.5 mM 48 hrs, 4-day adult
(407)
Ethanol 2.5% 3 hrs, larvae L3
(182)
Ethanol 5% 3 hrs, larvae L3
(269)
Ethanol 10% 3 hrs, larvae L3
(216)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(400)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(527)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(304)
Paraquat 5 mM 48 hrs, 4-day adult
(244)
Paraquat 10 mM 48 hrs, 4-day adult
(439)
Rotenone 2 μg 12 hrs, larvae L3
(124)
Rotenone 8 μg 12 hrs, larvae L3
(136)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
(229)
cold shock, 4-day adult
(180)
heat shock, 4-day adult
(167)
Cadmium 50 mM 6 hrs, larvae L3
(166)
Cadmium 50 mM 12 hrs, larvae L3
131
Cadmium 50 mM 48 hrs, 4-day adult
(318)
Cadmium 100 mM 48 hrs, 4-day adult
(411)
Copper 0.5 mM 12 hrs, larvae L3
(309)
Copper 15 mM 48 hrs, 4-day adult
(352)
Zinc 5 mM 12 hrs, larvae L3
(339)
Zinc 4.5 mM 48 hrs, 4-day adult
(407)
Ethanol 2.5% 3 hrs, larvae L3
(182)
Ethanol 5% 3 hrs, larvae L3
(269)
Ethanol 10% 3 hrs, larvae L3
(216)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(400)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(527)
Caffeine 25 mg/ml 48 hrs, 4-day adult
(304)
Paraquat 5 mM 48 hrs, 4-day adult
(244)
Paraquat 10 mM 48 hrs, 4-day adult
(439)
Rotenone 2 μg 12 hrs, larvae L3
124
Rotenone 8 μg 12 hrs, larvae L3
136
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
229
cold shock, 4-day adult
180
heat shock, 4-day adult
167
Cadmium 50 mM 6 hrs, larvae L3
166
Cadmium 50 mM 12 hrs, larvae L3
131
Cadmium 50 mM 48 hrs, 4-day adult
318
Cadmium 100 mM 48 hrs, 4-day adult
411
Copper 0.5 mM 12 hrs, larvae L3
309
Copper 15 mM 48 hrs, 4-day adult
352
Zinc 5 mM 12 hrs, larvae L3
339
Zinc 4.5 mM 48 hrs, 4-day adult
407
Ethanol 2.5% 3 hrs, larvae L3
182
Ethanol 5% 3 hrs, larvae L3
269
Ethanol 10% 3 hrs, larvae L3
216
Caffeine 1.5 mg/ml 4 hrs, larvae L3
400
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
527
Caffeine 25 mg/ml 48 hrs, 4-day adult
304
Paraquat 5 mM 48 hrs, 4-day adult
244
Paraquat 10 mM 48 hrs, 4-day adult
439
Rotenone 2 μg 12 hrs, larvae L3
124
Rotenone 8 μg 12 hrs, larvae L3
136
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 23 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 4 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Not disrupted in Partially disrupted in Transgenic Constructs & Insertions
Transgenic Constructs Insertions miscellaneous insertions
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
NA
insertion of enhancer trap binary system
insertion of enhancer trap
insertion of mobile activating element
Gene Ontology: Function, Process
& Cellular Component ( 7 unique terms ) Terms Based on
Experimental Evidence ( 5 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from direct assay
inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 2 terms ) Molecular Function inferred from sequence or structural similarity
Biological Process ( 0 terms) Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (12)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
No orthologs identified
Arthropod inclusive ortholog search
No orthologs identified
Metazoa inclusive ortholog search
No orthologs identified
Orthologs in Drosophila Species
(EOG6ZKK5Z )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 15 )Bloomington Harvard Kyoto VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 182 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Source for merge of: CG17836 anon-EST:Liang-2.44
Source for merge of: Xrp1 l(3)02515
Additional comments Other Comments RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 8 )Reported As Symbol Synonym CG17836
(
Sambandan et al., 2006 ,
Reiter et al., 2007 ,
Gruenewald et al., 2009 ,
Buszczak et al., 2007 ,
Baeg et al., 2007 ,
Brodsky et al., 2004 ,
Akdemir et al., 2007 ,
Minidorff et al., 2007 ,
FlyBase Curators, 2008 ,
Kankel et al., 2007 ,
Minidorff et al., 2007 ,
Carreira et al., 2009 ,
Keleman et al., 2009.8.5 ,
Zhou et al., 2008 ,
Ni et al., 2011.7.19 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym Secondary FlyBase
IDs FBgn0010781 FBgn0025952 FBgn0038661 References ( 44 )Generate a list of List References by type
Recent research papers ( 2 )
Takahashi et al., 2012, Evolution 66(9): 2878--2890Deficiency screening for genomic regions with effects on environmental sensitivity of the sensory bristles of Drosophila melanogaster. [FBrf0219405] Carreira et al., 2011, BMC Dev. Biol. 11: 32Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273]