αE5, DmαE5, Est-C
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\α-Est5 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\α-Est5 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Eleven putative esterase genes from the region containing the α-esterase cluster are cloned.
No difference in allele fixed in lines selected over 700 generations for high (negative) and low (positive) geotaxis.
Presumably one of α-Est1 to α-Est10, but precise relationship not determined.
Protein product identified as EST9 isozyme.
Allelic frequencies have been determined between European and African populations. African populations show a greater genetic diversity, as measured by the number of alleles found. Within each geographic group there is a homogeneity of allele frequencies.
Specifies EST-C, the next-to-most rapidly migrating of six anodally migrating esterases detectable with α-napthyl acetate and Fast Blue BB following starch gel electrophoresis. Enzyme a monomer. Putative null alleles homozygous viable, consistent with failure to find lethal complementation group within the interval.