αE5, DmαE5, Est-C
Please see the JBrowse view of Dmel\α-Est5 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.49
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\α-Est5 using the Feature Mapper tool.
Comment: maternally deposited
GBrowse - Visual display of RNA-Seq signals
View Dmel\α-Est5 in GBrowse 23-48
3-44.3
3-47.7
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: α-Est5 CG1089
Source for merge of: α-Est5 Est-C
Eleven putative esterase genes from the region containing the α-esterase cluster are cloned.
Corresponds to Est-9 of FBrf0053202.
Gramoxone has no mutagenic effect on the genetic background of Est-C.
No difference in allele fixed in lines selected over 700 generations for high (negative) and low (positive) geotaxis.
Presumably one of α-Est1 to α-Est10, but precise relationship not determined.
Protein product identified as EST9 isozyme.
Allelic frequencies have been determined between European and African populations. African populations show a greater genetic diversity, as measured by the number of alleles found. Within each geographic group there is a homogeneity of allele frequencies.
Specifies EST-C, the next-to-most rapidly migrating of six anodally migrating esterases detectable with α-napthyl acetate and Fast Blue BB following starch gel electrophoresis. Enzyme a monomer. Putative null alleles homozygous viable, consistent with failure to find lethal complementation group within the interval.