FB2020_06, released Dec 22, 2020

Gene: Dmel\α-Est5

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General Information
Symbol
Dmel\α-Est5
Species
D. melanogaster
Name
α-Esterase-5
Annotation Symbol
CG1089
Feature Type
protein_coding_gene
FlyBase ID
FBgn0261393
Gene Model Status
Current
Stock Availability
10 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Also Known As

αE5, DmαE5, Est-C

Key Links
Genomic Location
Cytogenetic map
84D9-84D5
Sequence location
3R:7,533,496..7,536,390 [-]
Recombination map

3-48

RefSeq locus
NT_033777 REGION:7533496..7536390
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (1 term)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables carboxylic ester hydrolase activity
inferred from direct assay
(Birner-Gruenberger et al., 2012, Campbell et al., 2003)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (0 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
OTHER CARBOXYLESTERASES -
OTHER CARBOXYLESTERASES are carboxylesterases that do not fall into any other major carboxylesterase group.
S9 NON-PEPTIDASE HOMOLOGS -
S9 non-peptidase homologs are similar in amino acid sequence to S9 serine peptidases but lack one or more of the expected catalytic residues. (Adapted from FBrf0239469.)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
Est-C
Specifies EST-C (EC 3.1.1.1), the next-to-most rapidly migrating of six anodally migrating esterases detectable with α-napthyl acetate and Fast Blue BB following starch gel electrophoresis. Enzyme a monomer. Putative null alleles homozygous viable, consistent with failure to find lethal complementation group within the interval.
Gene Model and Products
Number of Transcripts
2
Number of Unique Polypeptides
2

Please see the JBrowse view of Dmel\α-Est5 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.49

Sequence Ontology: Class of Gene
gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
α-Est5-RA
FBtr0081547
NM_079541
1754
542
α-Est5-RB
FBtr0307274
NM_001260036
2490
543
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
α-Est5-PA
FBpp0081071
61.4
542
6.08
NP_524265
AAF54006
α-Est5-PB
FBpp0298275
61.5
543
6.08
NP_001246965
AFH06284
Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\α-Est5 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\α-Est5 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 19 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of α-Est5
Transgenic constructs containing regulatory region of α-Est5
Deletions and Duplications ( 14 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
electrophoretic variant
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (18)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\CES1
5 of 15
Yes
No
Hsap\CES2
5 of 15
Yes
No
Hsap\CES3
5 of 15
Yes
No
Hsap\CES4A
5 of 15
Yes
No
Hsap\CES5A
5 of 15
Yes
No
Hsap\ACHE
4 of 15
No
No
1  
Hsap\BCHE
3 of 15
No
No
1  
Hsap\CEL
3 of 15
No
No
Hsap\NLGN1
3 of 15
No
No
1  
Hsap\NLGN2
3 of 15
No
No
Hsap\NLGN3
3 of 15
No
No
Hsap\NLGN4X
3 of 15
No
No
Hsap\TG
3 of 15
No
No
Hsap\LOC107987423
2 of 15
No
Yes
Hsap\NLGN4Y
2 of 15
No
No
Hsap\CD74
1 of 15
No
Yes
Hsap\NID1
1 of 15
No
No
Hsap\NID2
1 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (33)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Ces1a
5 of 15
Yes
No
Mmus\Ces1b
5 of 15
Yes
No
Mmus\Ces1c
5 of 15
Yes
No
Mmus\Ces1d
5 of 15
Yes
No
Mmus\Ces1e
5 of 15
Yes
No
Mmus\Ces1g
5 of 15
Yes
No
Mmus\Ces2a
5 of 15
Yes
No
Mmus\Ces2b
5 of 15
Yes
No
Mmus\Ces2e
5 of 15
Yes
No
Mmus\Ces2f
5 of 15
Yes
No
Mmus\Ces2g
5 of 15
Yes
No
Mmus\Ces2h
5 of 15
Yes
No
Mmus\Ces3a
5 of 15
Yes
No
Mmus\Ces3b
5 of 15
Yes
No
Mmus\Ces5a
5 of 15
Yes
No
Mmus\Ache
4 of 15
No
No
Mmus\Ces1f
4 of 15
No
No
Mmus\Ces1h
4 of 15
No
No
Mmus\Ces2c
4 of 15
No
No
Mmus\Ces4a
4 of 15
No
No
Mmus\Bche
3 of 15
No
No
Mmus\Nlgn1
3 of 15
No
No
Mmus\Nlgn2
3 of 15
No
No
Mmus\Nlgn3
3 of 15
No
No
Mmus\Tg
3 of 15
No
No
Mmus\Cel
2 of 15
No
No
Mmus\Adck5
1 of 15
No
No
Mmus\Cd74
1 of 15
No
Yes
Mmus\Clspn
1 of 15
No
No
Mmus\Gm2399
1 of 15
No
Yes
Mmus\Nid1
1 of 15
No
No
Mmus\Nid2
1 of 15
No
No
Mmus\Plekhg5
1 of 15
No
No
Rattus norvegicus (Norway rat) (37)
Rnor\Ces1a
6 of 13
Yes
No
Rnor\Ces1f
6 of 13
Yes
No
Rnor\Ces2g
6 of 13
Yes
No
Rnor\Ces2h
6 of 13
Yes
No
Rnor\Ces4a
6 of 13
Yes
No
Rnor\Ces5a
6 of 13
Yes
No
Rnor\Ces1c
5 of 13
No
No
Rnor\Ces1d
5 of 13
No
Yes
Rnor\Ces2i
5 of 13
No
No
Rnor\Ces2a
4 of 13
No
No
Rnor\Ces2e
4 of 13
No
No
Rnor\Ces2j
4 of 13
No
No
Rnor\Ces2
4 of 13
No
Yes
Rnor\LOC679149
4 of 13
No
No
Rnor\LOC100910040
4 of 13
No
Yes
Rnor\Bche
3 of 13
No
No
Rnor\Cel
3 of 13
No
No
Rnor\Ces1e
3 of 13
No
No
Rnor\Ces2c
3 of 13
No
No
Rnor\Nlgn2
3 of 13
No
No
Rnor\Nlgn3
3 of 13
No
No
Rnor\Tg
3 of 13
No
Yes
Rnor\Ache
2 of 13
No
No
Rnor\Ces3a
2 of 13
No
Yes
Rnor\Cesl1
2 of 13
No
No
Rnor\LOC688542
2 of 13
No
Yes
Rnor\LOC102548129
2 of 13
No
Yes
Rnor\Nlgn1
2 of 13
No
No
Rnor\Cd74
1 of 13
No
Yes
Rnor\LOC291863
1 of 13
No
Yes
Rnor\LOC679356
1 of 13
No
Yes
Rnor\LOC679368
1 of 13
No
Yes
Rnor\LOC100365112
1 of 13
No
Yes
Rnor\LOC102557406
1 of 13
No
Yes
Rnor\LOC108348093
1 of 13
No
Yes
Rnor\Nid1
1 of 13
No
No
Rnor\Nid2
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (22)
Xtro\ache
4 of 12
Yes
No
Xtro\ces2
4 of 12
Yes
No
Xtro\ces3
4 of 12
Yes
No
Xtro\LOC100494782
4 of 12
Yes
No
Xtro\bche
3 of 12
No
No
Xtro\cel
3 of 12
No
No
Xtro\nlgn2
3 of 12
No
No
Xtro\nlgn3
3 of 12
No
No
Xtro\nlgn4x
3 of 12
No
No
Xtro\tg
3 of 12
No
Yes
Xtro\bche
2 of 12
No
No
Xtro\ces1
2 of 12
No
Yes
Xtro\ces5a
2 of 12
No
Yes
Xtro\LOC100493652
2 of 12
No
Yes
Xtro\LOC100493819
2 of 12
No
Yes
Xtro\LOC100493994
2 of 12
No
Yes
Xtro\LOC100494295
2 of 12
No
Yes
Xtro\cd74
1 of 12
No
Yes
Xtro\LOC100492444
1 of 12
No
Yes
Xtro\nid1
1 of 12
No
No
Xtro\nid2
1 of 12
No
No
Xtro\nlgn1
1 of 12
No
No
Danio rerio (Zebrafish) (21)
Drer\ces2
5 of 15
Yes
No
Drer\ces3
5 of 15
Yes
No
Drer\ache
4 of 15
No
No
Drer\LOC100334697
4 of 15
No
No
Drer\si:dkey-30c15.17
4 of 15
No
Yes
Drer\cel.1
3 of 15
No
No
Drer\cel.2
3 of 15
No
No
Drer\nlgn1
3 of 15
No
No
Drer\nlgn2a
3 of 15
No
No
Drer\nlgn2b
3 of 15
No
No
Drer\nlgn3a
3 of 15
No
No
Drer\nlgn3b
3 of 15
No
No
Drer\nlgn4xa
3 of 15
No
No
Drer\nlgn4xb
3 of 15
No
No
Drer\si:ch211-71n6.4
3 of 15
No
No
Drer\si:ch211-93f2.1
3 of 15
No
No
Drer\tg
3 of 15
No
Yes
Drer\cd74a
1 of 15
No
Yes
Drer\nid1a
1 of 15
No
No
Drer\nid2a
1 of 15
No
No
Drer\si:dkey-193c22.1
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (47)
Cele\F07C4.12
9 of 15
Yes
Yes
Cele\F15A8.6
8 of 15
No
No
Cele\F56C11.6
8 of 15
No
Yes
Cele\K11G9.3
8 of 15
No
Yes
Cele\Y71H2AM.13
8 of 15
No
Yes
Cele\C52A10.1
7 of 15
No
Yes
Cele\F13H6.3
7 of 15
No
Yes
Cele\K11G9.2
7 of 15
No
Yes
Cele\B0238.7
6 of 15
No
Yes
Cele\K11G9.1
6 of 15
No
No
Cele\T28C12.4
6 of 15
No
No
Cele\B0238.1
5 of 15
No
No
Cele\C52A10.2
5 of 15
No
No
Cele\T07H6.1
5 of 15
No
No
Cele\ace-3
4 of 15
No
No
Cele\ace-4
4 of 15
No
No
Cele\C01B10.4
4 of 15
No
No
Cele\C01B10.10
4 of 15
No
No
Cele\C17H12.4
4 of 15
No
Yes
Cele\C23H4.3
4 of 15
No
No
Cele\C23H4.7
4 of 15
No
No
Cele\C42D4.2
4 of 15
No
No
Cele\cest-1
4 of 15
No
No
Cele\ges-1
4 of 15
No
No
Cele\K07C11.4
4 of 15
No
No
Cele\R173.3
4 of 15
No
No
Cele\T02B5.3
4 of 15
No
No
Cele\T22D1.11
4 of 15
No
No
Cele\ZC376.1
4 of 15
No
No
Cele\ZC376.2
4 of 15
No
No
Cele\ZC376.3
4 of 15
No
No
Cele\ace-1
3 of 15
No
No
Cele\ace-2
3 of 15
No
No
Cele\C23H4.2
3 of 15
No
No
Cele\C23H4.4
3 of 15
No
No
Cele\E01G6.3
3 of 15
No
No
Cele\F55F3.2
3 of 15
No
No
Cele\glit-1
3 of 15
No
No
Cele\T28C12.5
3 of 15
No
No
Cele\W02B12.4
3 of 15
No
No
Cele\F13H6.4
2 of 15
No
No
Cele\nlg-1
2 of 15
No
No
Cele\Y75B8A.3
2 of 15
No
No
Cele\ZK994.1
2 of 15
No
No
Cele\B0238.13
1 of 15
No
No
Cele\nid-1
1 of 15
No
No
Cele\Y71G12B.28
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (18)
Atha\AT1G19190
1 of 9
Yes
Yes
Atha\AT1G47480
1 of 9
Yes
Yes
Atha\AT1G49640
1 of 9
Yes
No
Atha\AT1G49650
1 of 9
Yes
Yes
Atha\AT1G68620
1 of 9
Yes
Yes
Atha\AT2G03550
1 of 9
Yes
No
Atha\AT2G45600
1 of 9
Yes
Yes
Atha\AT2G45610
1 of 9
Yes
Yes
Atha\AT5G06570
1 of 9
Yes
Yes
Atha\CXE5
1 of 9
Yes
Yes
Atha\CXE12
1 of 9
Yes
Yes
Atha\CXE13
1 of 9
Yes
Yes
Atha\CXE17
1 of 9
Yes
Yes
Atha\CXE18
1 of 9
Yes
Yes
Atha\CXE20
1 of 9
Yes
Yes
Atha\GID1A
1 of 9
Yes
Yes
Atha\GID1B
1 of 9
Yes
Yes
Atha\GID1C
1 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPCC417.12
3 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG0919021A )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00012110
Drosophila simulans
Dsim\GD19472
Drosophila sechellia
Dsec\GM10471
Drosophila erecta
Dere\GG25094
Drosophila yakuba
Dyak\GE24932
Drosophila yakuba
Dyak\GE25781
Drosophila yakuba
Dyak\GE15090
Drosophila ananassae
Dana\GF17295
Drosophila pseudoobscura pseudoobscura
Dpse\GA26214
Drosophila persimilis
Dper\GL12167
Drosophila willistoni
Dwil\GK11073
Drosophila willistoni
Dwil\GK11072
Drosophila willistoni
Dwil\GK11071
Drosophila virilis
Dvir\GJ10229
Drosophila mojavensis
Dmoj\GI23476
Drosophila grimshawi
Dgri\GH19267
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150099 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17026891
Musca domestica
House fly
Mdoa\17015757
Musca domestica
House fly
Mdoa\17015756
Musca domestica
House fly
Mdoa\17026890
Musca domestica
House fly
Mdoa\17015750
Musca domestica
House fly
Mdoa\17024402
Musca domestica
House fly
Mdoa\17021328
Musca domestica
House fly
Mdoa\17015754
Musca domestica
House fly
Mdoa\17013908
Musca domestica
House fly
Mdoa\17026892
Musca domestica
House fly
Mdoa\17021327
Musca domestica
House fly
Mdoa\17015751
Musca domestica
House fly
Mdoa\17015755
Musca domestica
House fly
Mdoa\17024408
Musca domestica
House fly
Mdoa\17021329
Glossina morsitans
Tsetse fly
Gmor\GMOY008971
Glossina morsitans
Tsetse fly
Gmor\GMOY008974
Glossina morsitans
Tsetse fly
Gmor\GMOY002162
Glossina morsitans
Tsetse fly
Gmor\GMOY008391
Glossina morsitans
Tsetse fly
Gmor\GMOY008972
Glossina morsitans
Tsetse fly
Gmor\GMOY008970
Glossina morsitans
Tsetse fly
Gmor\GMOY008973
Glossina morsitans
Tsetse fly
Gmor\GMOY002161
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_14079
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00588
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00585
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00586
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00587
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_00589
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_14080
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_12453
Mayetiola destructor
Hessian fly
Mdes\Mdes012289
Mayetiola destructor
Hessian fly
Mdes\Mdes014024
Mayetiola destructor
Hessian fly
Mdes\Mdes005459
Mayetiola destructor
Hessian fly
Mdes\Mdes008364
Mayetiola destructor
Hessian fly
Mdes\Mdes008205
Mayetiola destructor
Hessian fly
Mdes\Mdes008362
Mayetiola destructor
Hessian fly
Mdes\Mdes012787
Mayetiola destructor
Hessian fly
Mdes\Mdes000948
Mayetiola destructor
Hessian fly
Mdes\Mdes010235
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEJHE3F
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEAE3B
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL015578
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEAE6A
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL005123
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEJHE1O
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEJHE4F
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL005200
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEAE3O
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL015602
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEJHE2F
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL015264
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEAE1A
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEAE3A
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL010389
Aedes aegypti
Yellow fever mosquito
Aaeg\CCEAE1B
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL017071
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL012509
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL013543
Anopheles darlingi
American malaria mosquito
Adar\ADAC007930
Anopheles darlingi
American malaria mosquito
Adar\ADAC001540
Anopheles darlingi
American malaria mosquito
Adar\ADAC007723
Anopheles darlingi
American malaria mosquito
Adar\ADAC010310
Anopheles darlingi
American malaria mosquito
Adar\ADAC008552
Anopheles darlingi
American malaria mosquito
Adar\ADAC009156
Anopheles darlingi
American malaria mosquito
Adar\ADAC007716
Anopheles darlingi
American malaria mosquito
Adar\ADAC007929
Anopheles darlingi
American malaria mosquito
Adar\ADAC005448
Anopheles darlingi
American malaria mosquito
Adar\ADAC007136
Anopheles darlingi
American malaria mosquito
Adar\ADAC005454
Anopheles darlingi
American malaria mosquito
Adar\ADAC009160
Anopheles darlingi
American malaria mosquito
Adar\ADAC005450
Anopheles darlingi
American malaria mosquito
Adar\ADAC005449
Anopheles darlingi
American malaria mosquito
Adar\ADAC007137
Anopheles darlingi
American malaria mosquito
Adar\ADAC009159
Anopheles gambiae
Malaria mosquito
Agam\COEAE5G
Anopheles gambiae
Malaria mosquito
Agam\COEAE2G
Anopheles gambiae
Malaria mosquito
Agam\COEJHE1E
Anopheles gambiae
Malaria mosquito
Agam\COEAE7G
Anopheles gambiae
Malaria mosquito
Agam\COEAE3D
Anopheles gambiae
Malaria mosquito
Agam\COEAE2E
Anopheles gambiae
Malaria mosquito
Agam\COEJHE3E
Anopheles gambiae
Malaria mosquito
Agam\COEAE3G
Anopheles gambiae
Malaria mosquito
Agam\COEJHE4F
Anopheles gambiae
Malaria mosquito
Agam\AGAP006227
Anopheles gambiae
Malaria mosquito
Agam\COEAE6G
Anopheles gambiae
Malaria mosquito
Agam\COEJHE4E
Anopheles gambiae
Malaria mosquito
Agam\COEAE2F
Anopheles gambiae
Malaria mosquito
Agam\COEAE8O
Anopheles gambiae
Malaria mosquito
Agam\COEBE3C
Anopheles gambiae
Malaria mosquito
Agam\COEBE2C
Anopheles gambiae
Malaria mosquito
Agam\COEJHE5E
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ013175
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016341
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ007829
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ007824
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ013917
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ002073
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016337
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ007825
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016338
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016340
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ013918
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ007826
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ007828
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ000045
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ000047
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ002074
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ004752
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ006908
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ016336
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W022L )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA009544
Bombyx mori
Silkmoth
Bmor\BGIBMGA004683
Bombyx mori
Silkmoth
Bmor\BGIBMGA010328
Bombyx mori
Silkmoth
Bmor\BGIBMGA014599
Bombyx mori
Silkmoth
Bmor\BGIBMGA011218
Bombyx mori
Silkmoth
Bmor\BGIBMGA007547
Bombyx mori
Silkmoth
Bmor\BGIBMGA003517
Bombyx mori
Silkmoth
Bmor\BGIBMGA001964
Bombyx mori
Silkmoth
Bmor\BGIBMGA010988
Bombyx mori
Silkmoth
Bmor\BGIBMGA007546
Bombyx mori
Silkmoth
Bmor\BGIBMGA013812
Bombyx mori
Silkmoth
Bmor\BGIBMGA010969
Danaus plexippus
Monarch butterfly
Dple\DPOGS209311-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211427-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS201802-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS215579-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS203350-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS208493-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS201956-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS215929-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS201957-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211393-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS211843-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL002341
Heliconius melpomene
Postman butterfly
Hmel\HMEL013381
Heliconius melpomene
Postman butterfly
Hmel\HMEL002573
Heliconius melpomene
Postman butterfly
Hmel\HMEL003326
Heliconius melpomene
Postman butterfly
Hmel\HMEL010712
Heliconius melpomene
Postman butterfly
Hmel\HMEL014427
Heliconius melpomene
Postman butterfly
Hmel\HMEL009236
Heliconius melpomene
Postman butterfly
Hmel\HMEL009240
Heliconius melpomene
Postman butterfly
Hmel\HMEL017328
Heliconius melpomene
Postman butterfly
Hmel\HMEL014187
Heliconius melpomene
Postman butterfly
Hmel\HMEL005882
Heliconius melpomene
Postman butterfly
Hmel\HMEL008764
Heliconius melpomene
Postman butterfly
Hmel\HMEL017092
Heliconius melpomene
Postman butterfly
Hmel\HMEL002060
Heliconius melpomene
Postman butterfly
Hmel\HMEL007950
Apis florea
Little honeybee
Aflo\2147528995
Apis florea
Little honeybee
Aflo\2147635299
Apis florea
Little honeybee
Aflo\2809221348
Apis florea
Little honeybee
Aflo\2246293060
Apis mellifera
Western honey bee
Amel\LOC409801
Apis mellifera
Western honey bee
Amel\GB46514
Apis mellifera
Western honey bee
Amel\GB46515
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP16132
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP15500
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP15499
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP15498
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP22081
Bombus terrestris
Buff-tailed bumblebee
Bter\15214369
Bombus terrestris
Buff-tailed bumblebee
Bter\15204934
Bombus terrestris
Buff-tailed bumblebee
Bter\15204935
Bombus terrestris
Buff-tailed bumblebee
Bter\15209836
Bombus terrestris
Buff-tailed bumblebee
Bter\15204936
Linepithema humile
Argentine ant
Lhum\LH13030
Linepithema humile
Argentine ant
Lhum\LH13031
Linepithema humile
Argentine ant
Lhum\LH13032
Linepithema humile
Argentine ant
Lhum\LH25422
Linepithema humile
Argentine ant
Lhum\LH13028
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0014ab
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00315a
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG006390
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001170
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG016422
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001268
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG016419
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG016108
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005427
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG016421
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005428
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG016111
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001271
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001270
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001269
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11765
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04068
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_11836
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_03565
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_07466
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_01818
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_00292
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_01523
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_07465
Tribolium castaneum
Red flour beetle
Tcas\TC009692
Tribolium castaneum
Red flour beetle
Tcas\TC014687
Tribolium castaneum
Red flour beetle
Tcas\TC033339
Tribolium castaneum
Red flour beetle
Tcas\TC009691
Tribolium castaneum
Red flour beetle
Tcas\TC013193
Tribolium castaneum
Red flour beetle
Tcas\TC006241
Tribolium castaneum
Red flour beetle
Tcas\TC031257
Tribolium castaneum
Red flour beetle
Tcas\TC034086
Tribolium castaneum
Red flour beetle
Tcas\GLEAN_07922
Tribolium castaneum
Red flour beetle
Tcas\TC033627
Tribolium castaneum
Red flour beetle
Tcas\Est-6
Tribolium castaneum
Red flour beetle
Tcas\TC009698
Pediculus humanus
Human body louse
Phum\PHUM569560
Rhodnius prolixus
Kissing bug
Rpro\RPRC001592
Rhodnius prolixus
Kissing bug
Rpro\RPRC007702
Cimex lectularius
Bed bug
Clec\CLEC011785
Cimex lectularius
Bed bug
Clec\CLEC011781
Cimex lectularius
Bed bug
Clec\CLEC011778
Cimex lectularius
Bed bug
Clec\CLEC004611
Cimex lectularius
Bed bug
Clec\CLEC000398
Cimex lectularius
Bed bug
Clec\CLEC011704
Cimex lectularius
Bed bug
Clec\CLEC011782
Cimex lectularius
Bed bug
Clec\CLEC011708
Cimex lectularius
Bed bug
Clec\CLEC011702
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI005798
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006990
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI070239
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI069596
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI065364
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003067
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI084883
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI009024
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006386
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001181
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI56647
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI071719
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02226
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02219
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_02228
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_01720
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_00356
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_12960
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0203 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR003942
Ixodes scapularis
Black-legged tick
Isca\ISCW003278
Ixodes scapularis
Black-legged tick
Isca\ISCW022870
Ixodes scapularis
Black-legged tick
Isca\ISCW007849
Ixodes scapularis
Black-legged tick
Isca\ISCW022253
Ixodes scapularis
Black-legged tick
Isca\ISCW020819
Ixodes scapularis
Black-legged tick
Isca\ISCW024894
Ixodes scapularis
Black-legged tick
Isca\ISCW022245
Ixodes scapularis
Black-legged tick
Isca\ISCW023612
Ixodes scapularis
Black-legged tick
Isca\ISCW020830
Ixodes scapularis
Black-legged tick
Isca\ISCW020831
Ixodes scapularis
Black-legged tick
Isca\ISCW013353
Ixodes scapularis
Black-legged tick
Isca\ISCW022961
Ixodes scapularis
Black-legged tick
Isca\ISCW023613
Ixodes scapularis
Black-legged tick
Isca\ISCW020833
Ixodes scapularis
Black-legged tick
Isca\ISCW006206
Ixodes scapularis
Black-legged tick
Isca\ISCW017638
Ixodes scapularis
Black-legged tick
Isca\ISCW024395
Ixodes scapularis
Black-legged tick
Isca\ISCW020835
Ixodes scapularis
Black-legged tick
Isca\ISCW021542
Ixodes scapularis
Black-legged tick
Isca\ISCW005431
Ixodes scapularis
Black-legged tick
Isca\ISCW004315
Ixodes scapularis
Black-legged tick
Isca\ISCW014411
Ixodes scapularis
Black-legged tick
Isca\ISCW022244
Ixodes scapularis
Black-legged tick
Isca\ISCW022252
Ixodes scapularis
Black-legged tick
Isca\ISCW023611
Ixodes scapularis
Black-legged tick
Isca\ISCW012483
Ixodes scapularis
Black-legged tick
Isca\ISCW020832
Ixodes scapularis
Black-legged tick
Isca\ISCW009205
Ixodes scapularis
Black-legged tick
Isca\ISCW021541
Ixodes scapularis
Black-legged tick
Isca\ISCW024448
Ixodes scapularis
Black-legged tick
Isca\ISCW023610
Ixodes scapularis
Black-legged tick
Isca\ISCW020825
Ixodes scapularis
Black-legged tick
Isca\ISCW006896
Ixodes scapularis
Black-legged tick
Isca\ISCW020821
Ixodes scapularis
Black-legged tick
Isca\ISCW006617
Ixodes scapularis
Black-legged tick
Isca\ISCW022251
Ixodes scapularis
Black-legged tick
Isca\ISCW001837
Ixodes scapularis
Black-legged tick
Isca\ISCW020837
Ixodes scapularis
Black-legged tick
Isca\ISCW001079
Ixodes scapularis
Black-legged tick
Isca\ISCW007848
Ixodes scapularis
Black-legged tick
Isca\ISCW006205
Ixodes scapularis
Black-legged tick
Isca\ISCW003637
Ixodes scapularis
Black-legged tick
Isca\ISCW001748
Stegodyphus mimosarum
African social velvet spider
Smim\KFM57104.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM71196.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM64737.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM73380.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM64053.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur20g03250
Tetranychus urticae
Two-spotted spider mite
Turt\tetur17g00350
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g03150
Tetranychus urticae
Two-spotted spider mite
Turt\tetur17g00080
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g14170
Tetranychus urticae
Two-spotted spider mite
Turt\tetur24g01310
Tetranychus urticae
Two-spotted spider mite
Turt\tetur06g03330
Tetranychus urticae
Two-spotted spider mite
Turt\tetur31g00250
Tetranychus urticae
Two-spotted spider mite
Turt\tetur29g00820
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g05770
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g05760
Tetranychus urticae
Two-spotted spider mite
Turt\tetur16g02410
Tetranychus urticae
Two-spotted spider mite
Turt\tetur29g00970
Tetranychus urticae
Two-spotted spider mite
Turt\tetur10g05290
Tetranychus urticae
Two-spotted spider mite
Turt\tetur26g01130
Tetranychus urticae
Two-spotted spider mite
Turt\tetur17g00750
Tetranychus urticae
Two-spotted spider mite
Turt\tetur01g08680
Tetranychus urticae
Two-spotted spider mite
Turt\tetur16g02380
Tetranychus urticae
Two-spotted spider mite
Turt\tetur04g06770
Tetranychus urticae
Two-spotted spider mite
Turt\tetur207g00010
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g06373
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g01560
Tetranychus urticae
Two-spotted spider mite
Turt\tetur16g02390
Tetranychus urticae
Two-spotted spider mite
Turt\tetur25g00710
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g01710
Tetranychus urticae
Two-spotted spider mite
Turt\tetur29g00930
Tetranychus urticae
Two-spotted spider mite
Turt\tetur17g00090
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g01570
Tetranychus urticae
Two-spotted spider mite
Turt\tetur17g00300
Tetranychus urticae
Two-spotted spider mite
Turt\tetur309g00020
Tetranychus urticae
Two-spotted spider mite
Turt\tetur37g00590
Tetranychus urticae
Two-spotted spider mite
Turt\tetur30g01290
Tetranychus urticae
Two-spotted spider mite
Turt\tetur16g02420
Tetranychus urticae
Two-spotted spider mite
Turt\tetur24g02580
Tetranychus urticae
Two-spotted spider mite
Turt\tetur03g02700
Tetranychus urticae
Two-spotted spider mite
Turt\tetur29g00940
Tetranychus urticae
Two-spotted spider mite
Turt\tetur11g01500
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_192973
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_53255
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_305141
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_105042
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_312876
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_105048
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_305140
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G02UA )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\SPU_002970gn
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000020037
Ciona intestinalis
Vase tunicate
Cint\LOC100179034
Ciona intestinalis
Vase tunicate
Cint\LOC100181357
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (36)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
α-Est1
7 of 10
α-Est2
7 of 10
α-Est4
7 of 10
α-Est6
7 of 10
α-Est7
7 of 10
α-Est10
7 of 10
gas
7 of 10
α-Est3
6 of 10
α-Est9
6 of 10
CG3841
6 of 10
CG9287
6 of 10
α-Est8
5 of 10
CG4382
5 of 10
CG4757
5 of 10
CG9289
5 of 10
Est-6
5 of 10
Est-P
5 of 10
Est-Q
5 of 10
Glt
5 of 10
Jhedup
5 of 10
Jhe
5 of 10
Ace
4 of 10
CG6414
4 of 10
CG10175
4 of 10
clt
4 of 10
CG5397
3 of 10
CG10339
3 of 10
CG12869
3 of 10
Gli
3 of 10
Nlg3
3 of 10
Nrt
3 of 10
Nlg1
2 of 10
Nlg2
2 of 10
Nlg4
2 of 10
CG30095
1 of 10
Ndg
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CES1; carboxylesterase 1
    5 of 15
    114835
      CES2; carboxylesterase 2
      5 of 15
      605278
          CES3; carboxylesterase 3
          5 of 15
          605279
              CES4A; carboxylesterase 4A
              5 of 15
                  CES5A; carboxylesterase 5A
                  5 of 15
                  618678
                      ACHE; acetylcholinesterase (Cartwright blood group)
                      4 of 15
                      100740
                         
                        BCHE; butyrylcholinesterase
                        3 of 15
                        177400
                           
                          CEL; carboxyl ester lipase
                          3 of 15
                          114840
                          NLGN1; neuroligin 1
                          3 of 15
                          600568
                             
                            NLGN2; neuroligin 2
                            3 of 15
                            606479
                                NLGN3; neuroligin 3
                                3 of 15
                                300336
                                  NLGN4X; neuroligin 4 X-linked
                                  3 of 15
                                  300427
                                    TG; thyroglobulin
                                    3 of 15
                                    188450
                                      Functional Complementation Data
                                      Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                      Interactions
                                      Summary of Physical Interactions
                                      esyN Network Diagram
                                      Show neighbor-neighbor interactions:
                                      Select Layout:
                                      Legend:
                                      Protein
                                      RNA
                                      Selected Interactor(s)
                                      Interactions Browser
                                      View in Interactions Browser
                                      Please see the Physical Interaction reports below for full details
                                      protein-protein
                                      Physical Interaction
                                      Assay
                                      References
                                      α-Est5 - CG7737
                                      experimental knowledge based
                                      (Guruharsha et al., 2011)
                                      α-Est5 - HIP-R
                                      experimental knowledge based
                                      (Guruharsha et al., 2011)
                                      Summary of Genetic Interactions
                                      esyN Network Diagram
                                      Starting gene(s)
                                      Interaction type
                                      Interacting gene(s)
                                      Reference
                                      Starting gene(s)
                                      Interaction type
                                      Interacting gene(s)
                                      Reference
                                      External Data
                                      Linkouts
                                      DroID - A comprehensive database of gene and protein interactions.
                                      MIST (protein-protein) - An integrated Molecular Interaction Database
                                      Pathways
                                      Signaling Pathways (FlyBase)
                                      Metabolic Pathways
                                      External Data
                                      Linkouts
                                      Genomic Location and Detailed Mapping Data
                                      Chromosome (arm)
                                      3R
                                      Recombination map

                                      3-48

                                      Cytogenetic map
                                      84D9-84D5
                                      Sequence location
                                      3R:7,533,496..7,536,390 [-]
                                      FlyBase Computed Cytological Location
                                      Cytogenetic map
                                      Evidence for location
                                      84D9-84D5
                                      Limits computationally determined from genome sequence between P{EP}EP3060EP3060 and P{PZ}grn05930; Left limit from complementation mapping relative to rn (citation unavailable) Right limit from non-inclusion within Df(3R)D7 (citation unavailable)
                                      Experimentally Determined Cytological Location
                                      Cytogenetic map
                                      Notes
                                      References
                                      84D3-84D10
                                      (Robin, 1996.3.11)
                                      84D3-84D10
                                      (determined by in situ hybridisation)
                                      (Russell et al., 1996)
                                      84D3-84E2
                                      (determined by in situ hybridisation)
                                      (Oakeshott et al., 1993)
                                      Experimentally Determined Recombination Data
                                      Location

                                      3-48

                                      (FlyBase, 2016)

                                      3-44.3

                                      (Comeron et al., 2012)

                                      3-

                                      (Robin, 1996.3.11, Choudhary et al., 1992)

                                      3-47.7

                                      (Ohnishi and Voelker, 1982)
                                      Left of (cM)
                                      (Ohnishi and Voelker, 1982, Ohnishi and Voelker, 1979)
                                      Right of (cM)
                                      Notes

                                      The distance between Est-C and Fdh is estimated to be 0.0058 +/- 0.0022.

                                      (Mukai and Voelker, 1977)
                                      Stocks and Reagents
                                      Stocks (10)
                                      Genomic Clones (17)
                                       

                                      Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                                      cDNA Clones (10)
                                       

                                      Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                                      cDNA clones, fully sequenced
                                      BDGP DGC clones
                                      Other clones
                                      Drosophila Genomics Resource Center cDNA clones

                                      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                      cDNA Clones, End Sequenced (ESTs)
                                      BDGP DGC clones
                                      Other clones
                                      RNAi and Array Information
                                      Linkouts
                                      DRSC - Results frm RNAi screens
                                      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                      Antibody Information
                                      Laboratory Generated Antibodies
                                       
                                      Commercially Available Antibodies
                                       
                                      Other Information
                                      Relationship to Other Genes
                                      Source for database identify of

                                      Source for identity of: α-Est5 CG1089

                                      (Zhong, 1999.11)
                                      Source for database merge of

                                      Source for merge of: α-Est5 Est-C

                                      (Campbell et al., 2003)
                                      Additional comments
                                      Other Comments

                                      Eleven putative esterase genes from the region containing the α-esterase cluster are cloned.

                                      (Russell et al., 1996)

                                      Corresponds to Est-9 of FBrf0053202.

                                      (Oakeshott et al., 1993)

                                      Gramoxone has no mutagenic effect on the genetic background of Est-C.

                                      (el Abidin Salam et al., 1993)

                                      No difference in allele fixed in lines selected over 700 generations for high (negative) and low (positive) geotaxis.

                                      (Stoltenberg et al., 1992)

                                      Presumably one of α-Est1 to α-Est10, but precise relationship not determined.

                                      (Healy et al., 1991)

                                      Protein product identified as EST9 isozyme.

                                      (Healy et al., 1991)

                                      Allelic frequencies have been determined between European and African populations. African populations show a greater genetic diversity, as measured by the number of alleles found. Within each geographic group there is a homogeneity of allele frequencies.

                                      (David, 1982)

                                      No linkage disequilibrium has been detected between Gpdh, Mdh1, Adh, Hex-C, Est-C or Fdh.

                                      (Mukai and Voelker, 1977)

                                      Specifies EST-C, the next-to-most rapidly migrating of six anodally migrating esterases detectable with α-napthyl acetate and Fast Blue BB following starch gel electrophoresis. Enzyme a monomer. Putative null alleles homozygous viable, consistent with failure to find lethal complementation group within the interval.

                                      Origin and Etymology
                                      Discoverer
                                      Etymology
                                      Identification
                                      External Crossreferences and Linkouts ( 39 )
                                      Sequence Crossreferences
                                      NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                      GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                      RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                      UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                                      Other crossreferences
                                      BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                                      Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                      Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                      Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                      Flygut - An atlas of the Drosophila adult midgut
                                      FlyMine - An integrated database for Drosophila genomics
                                      GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                      InterPro - A database of protein families, domains and functional sites
                                      KEGG Genes - Molecular building blocks of life in the genomic space.
                                      modMine - A data warehouse for the modENCODE project
                                      Linkouts
                                      DPiM - Drosophila Protein interaction map
                                      DroID - A comprehensive database of gene and protein interactions.
                                      DRSC - Results frm RNAi screens
                                      FLIGHT - Cell culture data for RNAi and other high-throughput technologies
                                      MIST (protein-protein) - An integrated Molecular Interaction Database
                                      Synonyms and Secondary IDs (18)
                                      Datasets (0)
                                      Study focus (0)
                                      Experimental Role
                                      Project
                                      Project Type
                                      Title
                                      References (63)