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Gene Dmel\sxc

General Information
Symbol	Dmel\sxc	Species	D. melanogaster
Name	super sex combs	Annotation symbol	CG10392
Feature type	protein_coding_gene	FlyBase ID	FBgn0261403
Gene Model Status	Current	Stock availability	7 publicly available
Also Known As	Ogt, sxc/Ogt, l(2)NC130, l(2)02637
Genomic Location
Chromosome (arm)	2R	Recombination map	2-55.3
Cytogenetic map	41C1-41C2	Sequence location	2R:1,194,756..1,216,986 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene super sex combs is referred to in FlyBase by the symbol Dmel\sxc (CG10392, FBgn0261403). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: acetylglucosaminyltransferase activity. There is experimental evidence that it is involved in the biological process: protein glycosylation; wing disc development. 15 alleles are reported. The phenotypes of these alleles are annotated with: larval abdominal segment; multicellular structure; adult segment; thoracic segment; organ system subdivision; organ system; anatomical structure; larval abdominal segment 3; prothoracic segment; larval abdominal segment A1-7. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval hindgut, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, larval fat body, adult ovary, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626219_s_at completely aligns to an exonic region common to each of the 3 FlyBase-annotated transcript isoforms of sxc. Gene sequence location is 2R:1194756..1216986.
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	sxc: super sex combs (P.W. Ingham) Homozygous adults exhibit homeotic transformation of antenna to first leg, of second and third legs to first leg, of wing to haltere, and of abdominal segments A1, A4, and A5 to A2, A5, and A6, respectively. Homozygotes derived from homozygous female germ line exhibit transformation of larval thoracic and abdominal segments toward A8.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features BKN22189 HFA04911
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 41C1-41C2   Left limit from inclusion within Df(2R)M41A4 (citation unavailable) Right limit from inclusion within Df(2R)M41A4 (citation unavailable)
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	2-55.3
Left of (cM)
Right of (cM)	pr
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sxc for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Transposon inserted in intron <new comment>DGC clone LD16758 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sxc-RA FBtr0086085  NM_165426   3530   1059 sxc-RB FBtr0086084  NM_078896   3521   1059 sxc-RC FBtr0086086  NM_165427   3585   1059
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sxc-PA   FBpp0085421   118.6   1059   7.16     NP_724406   AAG22338 sxc-PB   FBpp0085420   118.6   1059   7.16     NP_523620   AAF57338 sxc-PC   FBpp0085422   118.6   1059   7.16     NP_724407   AAG22339
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Tetratricopeptide-like helical (IPR011990) Tetratricopeptide repeat-containing (IPR013026) Tetratricopeptide repeat (IPR019734) Tetratricopeptide TPR-1 (IPR001440)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA438669   AA438806   AA439659   AA441494   AA536259   AA536422   AA539129   AA695112   AA695736   AA695874   AA801699   AA816524   AE013599 AAF57338   AE013599 AAG22338   AE013599 AAG22339   AF145622 AAD38597   AF217788 AAF32311   AI064003   AI401949   AI546681   AW942428   AY061225 AAL28773   BG636411   BG641238   BI212404   BI229932   BI354949   BI356118   BI356865   BI365039   BI370366   BI370693   BI482725   BI483392   BI486649   BI612965   BI624268   BI631365   BI640325   BP554231   BT032865   CO178812   CO181217   CO182693   CO185016   CO187341   CO189088   CO195896   CO264013   CO264113   CO266044   CO268029   CO268160   CO269419   CO269676   CO274575   CO280135   CO280399   CO282773   CO283262   CO289835   CO292766   CO294142   CO303851   CO308184   CO317397   CO318662   CO324228   CO324235   CO325133   CO327884   CO328974   CO337594   CO339994   CO340777   DN154021   EC057178   EC060848   EC063441   EC073475   EC074681   EC075269   EC077988   EC081179   EC089075   EC197110   EC199001   EC199261   EC204368   EC206246   EC208683   EC210631   EC212050   EC217902   EC220168   EC222302   EC229843   EC232622   EC233827   EC234088   EC235606   EC244169   EC246979   EC255785   EC257710   EC262455   EV578945   EV581839   EV584260   EV590406   FE862756   FE862788   FE862825   FE862842   FE862843   FE862886   FE862933   FE863121   FE863129   FE863341   FE863353   FE863380   FE863384   GH738908   GH739025   GH739090   GH739240   GH739242   GH739620   GH739711   GH740007   GH740137   GH740150   GH740309   GH740534   GH740615   GH740663   GH740792   GH740987   GH741089   GH741409   GH741473   GH741499   GH741600   GH741995   GH742137   GH742241   GH742262   GH742555   GH742624   GH742671   GH742783   GH742847   GH743189   GH743190   GH743194   GH743270   GH743399   GH743527   GH743567   GH743629   GH743764   GH743832   GH743910   GH744008   GH744195   GH744310   GH744343   GH744368   GH744705   GH744756   GH744848   GH745012   GH745359   GH745588   GH745624   GH745694   GH745703   GH745721   GH745738   GH746125   GH746268   GH746479   GH746574   GH746733   GH746898   GH747111   GH747115   GH747198   GH747253   GH747572   GH761444   GH761524   GH761527   GH761616   GH761903   GH761927   GH762434   GH762659   GH762853   GH762938   GH763139   GH763396   GH763482   GH763484   GH763567   GH763715   GH764045   GH764234   GH764330   GH764431   GH764492   GH764630   GH764670   GH764999   GH765149   GH765150   GH765373   GH765438   GH765463   GH765530   GH765539   GH765560   GH765912   GH766007   GH766241   GH766292   GH766324   GH766415   GH766494   GH766555   GH766578   GH767016   GH767062   GH767258   GH767455   GH767482   GH767865   GH768397   GH768518   GH768610   GH768957   GH769289   GH769292   GH769302   GH769340   GH769371   GH769550   GH769579   GH769787   GH769791   GH769825   GH769879   GH769892   GH769893   GH779314   GH779812   GH780456   GH782363   GH794995   GH805976   GH845226   GH872666   GH907970   GH910629   GH918945   GH929039   GH933067   GH937821
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95RP9 Q9Y148 Q7KJA9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0261403    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0261403 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0261403 expression level Developmental Stage   Expression Level embryo 00-02hr    2785 embryo 02-04hr    4398 embryo 04-06hr    3715 embryo 06-08hr    3026 embryo 08-10hr    4272 embryo 10-12hr    4610 embryo 12-14hr    5516 embryo 14-16hr    1498 embryo 16-18hr    3065 embryo 18-20hr    1930 embryo 20-22hr    3012 embryo 22-24hr    4177 larva L1    1301 larva L2    1794 larva L3 12hr old    1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6    1699 larva L3 puffstage 7-9    2857 white prepupae new    2795 white prepupae 12hr    2020 white prepupae 24hr    1911 pupae 2d postWPP    2045 pupae 3d postWPP    2143 pupae 4d postWPP    907 adult male 01day    1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day    2632 adult female 30day    2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2785) embryo 02-04hr  (4398) embryo 04-06hr  (3715) embryo 06-08hr  (3026) embryo 08-10hr  (4272) embryo 10-12hr  (4610) embryo 12-14hr  (5516) embryo 14-16hr  (1498) embryo 16-18hr  (3065) embryo 18-20hr  (1930) embryo 20-22hr  (3012) embryo 22-24hr  (4177) larva L1  (1301) larva L2  (1794) larva L3 12hr old  (1477) larva L3 puffstage 1-2  (1367) larva L3 puffstage 3-6  (1699) larva L3 puffstage 7-9  (2857) white prepupae new  (2795) white prepupae 12hr  (2020) white prepupae 24hr  (1911) pupae 2d postWPP  (2045) pupae 3d postWPP  (2143) pupae 4d postWPP  (907) adult male 01day  (1697) adult male 05day  (1082) adult male 30day  (652) adult female 01day  (1066) adult female 05day  (2632) adult female 30day  (2075) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2785) embryo 02-04hr  (4398) embryo 04-06hr  (3715) embryo 06-08hr  (3026) embryo 08-10hr  (4272) embryo 10-12hr  (4610) embryo 12-14hr  (5516) embryo 14-16hr  1498 embryo 16-18hr  (3065) embryo 18-20hr  (1930) embryo 20-22hr  (3012) embryo 22-24hr  (4177) larva L1    1301 larva L2  (1794) larva L3 12hr old  1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6  (1699) larva L3 puffstage 7-9  (2857) white prepupae new  (2795) white prepupae 12hr  (2020) white prepupae 24hr  (1911) pupae 2d postWPP  (2045) pupae 3d postWPP  (2143) pupae 4d postWPP    907 adult male 01day  (1697) adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day  (2632) adult female 30day  (2075) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2785 embryo 02-04hr    4398 embryo 04-06hr    3715 embryo 06-08hr    3026 embryo 08-10hr    4272 embryo 10-12hr    4610 embryo 12-14hr    5516 embryo 14-16hr    1498 embryo 16-18hr    3065 embryo 18-20hr    1930 embryo 20-22hr    3012 embryo 22-24hr    4177 larva L1    1301 larva L2    1794 larva L3 12hr old    1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6    1699 larva L3 puffstage 7-9    2857 white prepupae new    2795 white prepupae 12hr    2020 white prepupae 24hr    1911 pupae 2d postWPP    2045 pupae 3d postWPP    2143 pupae 4d postWPP    907 adult male 01day    1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day    2632 adult female 30day    2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2785 embryo 02-04hr    4398 embryo 04-06hr    3715 embryo 06-08hr    3026 embryo 08-10hr    4272 embryo 10-12hr    4610 embryo 12-14hr    5516 embryo 14-16hr    1498 embryo 16-18hr    3065 embryo 18-20hr    1930 embryo 20-22hr    3012 embryo 22-24hr    4177 larva L1    1301 larva L2    1794 larva L3 12hr old    1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6    1699 larva L3 puffstage 7-9    2857 white prepupae new    2795 white prepupae 12hr    2020 white prepupae 24hr    1911 pupae 2d postWPP    2045 pupae 3d postWPP    2143 pupae 4d postWPP    907 adult male 01day    1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day    2632 adult female 30day    2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0261403 expression level Developmental Stage   Expression Level embryo 00-02hr    2785 embryo 02-04hr    4398 embryo 04-06hr    3715 embryo 06-08hr    3026 embryo 08-10hr    4272 embryo 10-12hr    4610 embryo 12-14hr    5516 embryo 14-16hr    1498 embryo 16-18hr    3065 embryo 18-20hr    1930 embryo 20-22hr    3012 embryo 22-24hr    4177 larva L1    1301 larva L2    1794 larva L3 12hr old    1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6    1699 larva L3 puffstage 7-9    2857 white prepupae new    2795 white prepupae 12hr    2020 white prepupae 24hr    1911 pupae 2d postWPP    2045 pupae 3d postWPP    2143 pupae 4d postWPP    907 adult male 01day    1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day    2632 adult female 30day    2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2785) embryo 02-04hr  (4398) embryo 04-06hr  (3715) embryo 06-08hr  (3026) embryo 08-10hr  (4272) embryo 10-12hr  (4610) embryo 12-14hr  (5516) embryo 14-16hr  (1498) embryo 16-18hr  (3065) embryo 18-20hr  (1930) embryo 20-22hr  (3012) embryo 22-24hr  (4177) larva L1  (1301) larva L2  (1794) larva L3 12hr old  (1477) larva L3 puffstage 1-2  (1367) larva L3 puffstage 3-6  (1699) larva L3 puffstage 7-9  (2857) white prepupae new  (2795) white prepupae 12hr  (2020) white prepupae 24hr  (1911) pupae 2d postWPP  (2045) pupae 3d postWPP  (2143) pupae 4d postWPP  (907) adult male 01day  (1697) adult male 05day  (1082) adult male 30day  (652) adult female 01day  (1066) adult female 05day  (2632) adult female 30day  (2075) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2785) embryo 02-04hr  (4398) embryo 04-06hr  (3715) embryo 06-08hr  (3026) embryo 08-10hr  (4272) embryo 10-12hr  (4610) embryo 12-14hr  (5516) embryo 14-16hr  1498 embryo 16-18hr  (3065) embryo 18-20hr  1930 embryo 20-22hr  (3012) embryo 22-24hr  (4177) larva L1    1301 larva L2  1794 larva L3 12hr old  1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6  1699 larva L3 puffstage 7-9  (2857) white prepupae new  (2795) white prepupae 12hr  2020 white prepupae 24hr  1911 pupae 2d postWPP  2045 pupae 3d postWPP  2143 pupae 4d postWPP    907 adult male 01day  1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day  (2632) adult female 30day  2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2785 embryo 02-04hr    4398 embryo 04-06hr    3715 embryo 06-08hr    3026 embryo 08-10hr    4272 embryo 10-12hr    4610 embryo 12-14hr    5516 embryo 14-16hr    1498 embryo 16-18hr    3065 embryo 18-20hr    1930 embryo 20-22hr    3012 embryo 22-24hr    4177 larva L1    1301 larva L2    1794 larva L3 12hr old    1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6    1699 larva L3 puffstage 7-9    2857 white prepupae new    2795 white prepupae 12hr    2020 white prepupae 24hr    1911 pupae 2d postWPP    2045 pupae 3d postWPP    2143 pupae 4d postWPP    907 adult male 01day    1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day    2632 adult female 30day    2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2785 embryo 02-04hr    4398 embryo 04-06hr    3715 embryo 06-08hr    3026 embryo 08-10hr    4272 embryo 10-12hr    4610 embryo 12-14hr    5516 embryo 14-16hr    1498 embryo 16-18hr    3065 embryo 18-20hr    1930 embryo 20-22hr    3012 embryo 22-24hr    4177 larva L1    1301 larva L2    1794 larva L3 12hr old    1477 larva L3 puffstage 1-2    1367 larva L3 puffstage 3-6    1699 larva L3 puffstage 7-9    2857 white prepupae new    2795 white prepupae 12hr    2020 white prepupae 24hr    1911 pupae 2d postWPP    2045 pupae 3d postWPP    2143 pupae 4d postWPP    907 adult male 01day    1697 adult male 05day    1082 adult male 30day    652 adult female 01day    1066 adult female 05day    2632 adult female 30day    2075 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0261403    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0261403 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult eye, larval/adult central nervous system, adult crop, larval hindgut, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, larval/adult midgut, adult hindgut, larval/adult Malpighian tubules, larval fat body, adult ovary, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0261403 expression level Tissue   Expression Level Larval Central Nervous System    783.125 Larval Midgut    415.5 Larval Hindgut    566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland    601.2 Larval Trachea    611.75 Larval Carcass    703.4 Adult Head    393.1 Adult Eye    673.6 Adult Brain    660.2 Adult Thoracic-Abdominal Ganglion    813.2 Adult Crop    537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body    648.7 Adult Salivary Gland    601.5 Adult Heart    640.85 Adult VirginFemale Spermatheca    586.2 Adult InseminatedFemale Spermatheca    692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (783.125) Larval Midgut    415.5 Larval Hindgut  (566.5) Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland  (601.2) Larval Trachea  (611.75) Larval Carcass  (703.4) Adult Head    393.1 Adult Eye  (673.6) Adult Brain  (660.2) Adult Thoracic-Abdominal Ganglion  (813.2) Adult Crop  537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body  (648.7) Adult Salivary Gland  (601.5) Adult Heart  (640.85) Adult VirginFemale Spermatheca  (586.2) Adult InseminatedFemale Spermatheca  (692.4) Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    783.125 Larval Midgut    415.5 Larval Hindgut    566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland    601.2 Larval Trachea    611.75 Larval Carcass    703.4 Adult Head    393.1 Adult Eye    673.6 Adult Brain    660.2 Adult Thoracic-Abdominal Ganglion    813.2 Adult Crop    537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body    648.7 Adult Salivary Gland    601.5 Adult Heart    640.85 Adult VirginFemale Spermatheca    586.2 Adult InseminatedFemale Spermatheca    692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    783.125 Larval Midgut    415.5 Larval Hindgut    566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland    601.2 Larval Trachea    611.75 Larval Carcass    703.4 Adult Head    393.1 Adult Eye    673.6 Adult Brain    660.2 Adult Thoracic-Abdominal Ganglion    813.2 Adult Crop    537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body    648.7 Adult Salivary Gland    601.5 Adult Heart    640.85 Adult VirginFemale Spermatheca    586.2 Adult InseminatedFemale Spermatheca    692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0261403 expression level Tissue   Expression Level Larval Central Nervous System    783.125 Larval Midgut    415.5 Larval Hindgut    566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland    601.2 Larval Trachea    611.75 Larval Carcass    703.4 Adult Head    393.1 Adult Eye    673.6 Adult Brain    660.2 Adult Thoracic-Abdominal Ganglion    813.2 Adult Crop    537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body    648.7 Adult Salivary Gland    601.5 Adult Heart    640.85 Adult VirginFemale Spermatheca    586.2 Adult InseminatedFemale Spermatheca    692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  783.125 Larval Midgut    415.5 Larval Hindgut  566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland  601.2 Larval Trachea  611.75 Larval Carcass  703.4 Adult Head    393.1 Adult Eye  673.6 Adult Brain  660.2 Adult Thoracic-Abdominal Ganglion  813.2 Adult Crop  537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body  648.7 Adult Salivary Gland  601.5 Adult Heart  640.85 Adult VirginFemale Spermatheca  586.2 Adult InseminatedFemale Spermatheca  692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    783.125 Larval Midgut    415.5 Larval Hindgut    566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland    601.2 Larval Trachea    611.75 Larval Carcass    703.4 Adult Head    393.1 Adult Eye    673.6 Adult Brain    660.2 Adult Thoracic-Abdominal Ganglion    813.2 Adult Crop    537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body    648.7 Adult Salivary Gland    601.5 Adult Heart    640.85 Adult VirginFemale Spermatheca    586.2 Adult InseminatedFemale Spermatheca    692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    783.125 Larval Midgut    415.5 Larval Hindgut    566.5 Larval Malpighian Tubules    480.9 Larval Fat Body    301.8 Larval Salivary Gland    601.2 Larval Trachea    611.75 Larval Carcass    703.4 Adult Head    393.1 Adult Eye    673.6 Adult Brain    660.2 Adult Thoracic-Abdominal Ganglion    813.2 Adult Crop    537.4 Adult Midgut    329.9 Adult Hindgut    377.9 Adult Malpighian Tubules    332.7 Adult Fat Body    648.7 Adult Salivary Gland    601.5 Adult Heart    640.85 Adult VirginFemale Spermatheca    586.2 Adult InseminatedFemale Spermatheca    692.4 Adult Ovary    453.7 Adult Testis    67.7 Adult Male Accessory Gland    429 Adult Carcass    430.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    393.1   NA  Eye    673.6   NA  Brain    660.2   783.125  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    813.2   NA  Crop    537.4   415.5  Midgut    329.9   566.5  Hindgut    377.9   480.9  Malpighian Tubules    332.7   301.8  Fat Body    648.7   601.2  Salivary Gland    601.5   NA  Heart    640.85   611.75  Trachea    NA   NA  VirginFemale Spermatheca    586.2   NA  InseminatedFemale Spermatheca    692.4   NA  Ovary    453.7   NA  Testis    67.7   NA  Male Accessory Gland    429   703.4  Carcass    430.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0261403
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal sxc02637 lethal, with Scer\GAL4tub.PU sxcdsRNA.Sym.Scer\UAS sxcGD6968 lethal, with Scer\GAL4tub.PU, sxc3 sxcdsRNA.Sym.Scer\UAS lethal, with Scer\GAL4tub.PU, sxcdsRNA.Sym.Scer\UAS sxc3 lethal (with sxc3) sxc02637 lethal (with sxc02637) sxc3 lethal | larval stage | recessive sxc3 sxc4 lethal | pharate adult stage (with Df(2R)nap1) sxc7 lethal | pharate adult stage (with sxc1) sxc6 sxc7 lethal | pharate adult stage (with sxc3) sxc6 sxc7 lethal | pharate adult stage (with sxc4) sxc6 sxc7 lethal | pharate adult stage (with sxc5) sxc6 sxc7 lethal | pharate adult stage (with sxc6) sxc1 sxc3 sxc4 sxc5 lethal | pharate adult stage (with sxc7) sxc1 sxc3 sxc4 sxc5 lethal | recessive sxc6 sxc02637 sxcNC130 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 sxcGD6968 viable (with sxc1) sxc2 viable (with sxc2) sxc1 sxc3 sxc4 sxc5 sxc6 sxc7 viable (with sxc3) sxc2 viable (with sxc4) sxc2 viable (with sxc5) sxc2 viable (with sxc6) sxc2 viable (with sxc7) sxc2 Sterility Allele fertile (with sxc1) sxc2 fertile (with sxc2) sxc1 sxc3 sxc4 sxc5 sxc6 sxc7 fertile (with sxc3) sxc2 fertile (with sxc4) sxc2 fertile (with sxc5) sxc2 fertile (with sxc6) sxc2 fertile (with sxc7) sxc2 Other Phenotypes Allele large body | adult stage, with Scer\GAL4Ilp2.PR sxcScer\UAS.T:Hsap\MYC large body | third instar larval stage, with Scer\GAL4Ilp2.PR sxcScer\UAS.T:Hsap\MYC small body | adult stage, with Scer\GAL4Ilp2.PR sxcGD6968 small body | third instar larval stage, with Scer\GAL4Ilp2.PR sxcGD6968 visible, with Scer\GAL4pnr-MD237 sxcGD6968 Phenotype manifest in Allele abdominal segment 1 sxc1 abdominal segment 4 sxc1 abdominal segment 5 sxc1 antenna sxc1 larval abdominal segment 1 sxc1 larval abdominal segment 2 sxc1 larval abdominal segment 3 sxc1 larval abdominal segment 4 sxc1 larval abdominal segment 5 sxc1 larval abdominal segment 6 sxc1 larval abdominal segment 7 sxc1 larval mesothoracic segment sxc1 larval metathoracic segment sxc1 larval prothoracic segment sxc1 mesothoracic leg sxc1 mesothoracic tergum, with Scer\GAL4pnr-MD237 sxcGD6968 metathoracic leg sxc1 sex comb | ectopic, with Scer\GAL4tub.PU, sxc3 sxcdsRNA.Sym.Scer\UAS sex comb | ectopic, with Scer\GAL4tub.PU, sxcdsRNA.Sym.Scer\UAS sxc3 wing sxc1 wing (with sxc1) sxc2 wing (with sxc2) sxc7 sxc1 sxc6 sxc3 sxc4 sxc5 wing (with sxc3) sxc2 wing (with sxc4) sxc2 wing (with sxc5) sxc2 wing (with sxc6) sxc2 wing (with sxc7) sxc2 wing vein | ectopic, with Scer\GAL4tub.PU, sxc3/sxc02637 sxcScer\UAS.cSa wing vein | ectopic (with sxc3), with Scer\GAL4tub.PU, sxcScer\UAS.cSa sxc02637 wing vein | ectopic (with sxc02637), with Scer\GAL4tub.PU, sxcScer\UAS.cSa sxc3
Classical Alleles ( 10 )
For All Classical Alleles Show
Allele of sxc Class Mutagen Stocks Known lesion sxc1 amorphic allele - genetic evidence ethyl methanesulfonate 3 Yes sxc6 loss of function allele ethyl methanesulfonate 1 Yes sxcMI02286 1 -- sxc3 loss of function allele, amorphic allele - genetic evidence, hypomorphic allele - genetic evidence ethyl methanesulfonate 0 -- sxc4 amorphic allele - genetic evidence ethyl methanesulfonate 0 Yes sxc02637 0 Yes sxc2 X ray 0 Yes sxc5 ethyl methanesulfonate 0 Yes sxc7 loss of function allele 0 Yes sxcNC130 ethyl methanesulfonate 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sxc Class Mutagen Stocks Known lesion sxcGD6968 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes sxcdsRNA.Sym.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes sxcKK102123 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes sxcScer\UAS.cSa in vitro construct - regulatory fusion 0 Yes sxcScer\UAS.T:Hsap\MYC in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)M41A4 (Sinclair et al., 2009) Df(2R)M41A8 (Myster et al., 2004, Sinclair et al., 2009, Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009, Myster et al., 2004) Df(2R)nap1 (Myster et al., 2004, Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009) Df(2R)nap4 (Gambetta and Mueller, 2009.8.18) Df(2R)nap8 (Gambetta and Mueller, 2009.8.18) Df(2R)NC13 (Myster and Peifer, 2003.9.11, Myster et al., 2004) Df(2R)NC31 (Sinclair et al., 2009) Df(2R)NC32 (Myster et al., 2004, Myster and Peifer, 2003.9.11, Gambetta and Mueller, 2009.8.18) Df(2R)NC50 (Myster et al., 2004) Df(2R)NC68 (Myster et al., 2004) Df(2R)NC73 (Myster et al., 2004, Myster and Peifer, 2003.9.11) Df(2R)NC125 (Myster et al., 2004) Df(2R)NC167 (Myster et al., 2004) Df(2R)NC191 (Myster et al., 2004) Df(2R)NC202 (Myster et al., 2004) Df(2R)NC218 (Myster et al., 2004) Df(2R)NC228 (Myster et al., 2004, Myster and Peifer, 2003.9.11) Df(2R)Nipped-D263.3 (Sinclair et al., 2009)
Not disrupted in	Df(2R)244 (Myster et al., 2004) Df(2R)247 (Myster et al., 2004) Df(2R)Dark2 (Myster et al., 2004) Df(2R)M41A2 (Myster et al., 2004, Myster et al., 2004) Df(2R)M41A10 (Sinclair et al., 2009, Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009, Myster et al., 2004, Myster et al., 2004) Df(2R)nap11 (Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009) Df(2R)NC98 (Myster et al., 2004) Df(2R)NC168 (Myster et al., 2004) Df(2R)NC195 (Myster et al., 2004) Df(2R)NC207 (Myster et al., 2004) Df(2R)NC219 (Myster et al., 2004) Df(2R)NC1198 (Myster et al., 2004) Df(2R)Nipped-D (Myster et al., 2004, Myster et al., 2004)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{KK102123} NA P{Sym-UAS-sxc} NA P{UAS-sxc.Myc} NA P{UAS-sxc.S} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}sxcMI02286 NA Transpac{}sxc02637 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function
CV term Evidence References
acetylglucosaminyltransferase activity inferred from mutant phenotype (Sinclair et al., 2009)
Biological Process
CV term Evidence References
protein glycosylation inferred from mutant phenotype (Gambetta et al., 2009, Gambetta et al., 2009) wing disc development inferred from mutant phenotype (Gambetta et al., 2009)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011990 (FlyBase Curators et al., 2004-) transferase activity, transferring glycosyl groups non-traceable author statement (Rubenstein, 1999.12.20)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sxc allele Gene References sxc1 mxc (Saget et al., 1998) trx (Gildea et al., 2000) sxc3 Asx (Milne et al., 1999) sxc4 E(z) (Bajusz et al., 2001) unspecified ash1 (Gildea et al., 2000) Asx (Campbell et al., 1995) esc (Campbell et al., 1995) Pc (Campbell et al., 1995) Sce (Campbell et al., 1995)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61400 DroID - A comprehensive database of gene and protein interactions. • FBgn0261403 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35486
Orthologs
Genome-wide drosophilid orthologs	Dana\GF13981 Dere\GG16710 Dgri\GH21711 Dmoj\GI18858 Dper\GL13214 Dpse\GA29107 Dsec\GM11101 Dsim\GD17889 Dvir\GJ20442 Dwil\GK21381 Dyak\GE11251
Curated drosophilid orthologs
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17775 PB17773 PB17770 LH20126 ISCW016709 ISCW016010 ISCW011456 FBgn0229070 FBgn0223373 FBgn0207582 FBgn0189436 FBgn0178111 FBgn0166046 FBgn0250465 JGI_V11_324191 FBgn0249057 FBgn0150820 FBgn0141597 FBgn0129682 FBgn0129172 FBgn0108940 FBgn0091008 CPIJ004572 CPIJ004573 CPIJ004574 BGIBMGA011033 BGIBMGA000643 ACYPI006692 ACYPI004112 ACYPI002146 ACYPI001221 GB13441 AGAP006254 AAEL014746 AAEL012365 PHUM581590 GLEAN_03916
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	3058 sxc1 bw1 sp1/SM5 7182 sxc6 cn1 bw1/SM1 34307 y1 w*; Mi{MIC}sxcMI02286
Kyoto	106810 sxc1 bw1 sp1/SM5 101559 sxc1 bw1 sp1 / SM5
VDRC	v18610 w1118; P{GD6968}v18610 v18611 w1118; P{GD6968}v18611
Genomic Clones ( 3 )
	BACR02D22 BACR07H20 BACR32F22 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 261 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH04245 LD16758 SD06381
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM02155 GM03343 GM04396 GM04695 GM29014 LD02013 LD12990 LD13163 LD14283 LD16449 LD17029 LD17217 RE17491 RE27828 RE42179 RE43126 RE50258 RE56860 RE57412 RE65458 RE66283 RE70104 RH41991 RH60918 RH63802 SD10051 SD12533 SD14120 SD23151
Other clones	13061 28499 29300 34676 39002 39103 40226 42014 43460 45622 64763 64769 67526 71367 72150 74270 153451 161571 172613 214317.41 214505.35 569277 CK01.15D.H3 CK01.20B.G5 CK01.33B.E4 CK01.53A.H12 CK01.72D.F7 CK01.118B.G12 CK01.124B.E12 CK01.129A.H5 Dmel_dig_000783_0634_3755 Dmel_dig_004994_0697_1167 Dmel_dig_014246_0592_0859 Dmel_neb_013224_0363_2160 EC13808 EC23672 EC29135 EC42672 EK028350 EK042962 EK057624 EK072205 EK089960 EK090405 EK094452 EK095524 EK114516 EK137159 EK137522 EK144759 EK152713 EK153954 EK155048 EK161164 EK162727 EK193025 EK193033 EK195653 EK200923 EK206204 EK242951 EK256933 EK267919 EK273341 EK291760 EN14860 EP08212 EP09834 EP11328 FGM228G03 RM06648 RM06649 RM06748 RM06749 RM06849 RM06949 RM07048 RM07049 RM07148 RM07248 RM07249 RM07348 RM07349 RP01067 RP01080 RP01238 RP001000861 RP001003616 RP001004221 RP001004514 RP001004612 RP001004831 RP001004899 RP001005000 RP001005166 RP001005363 RP001005431 RP001005619 RP001005848 RP001006497 RP001006861 RP001007441 RP001008071 RP001008280 RP001009184 RP001009800 RP001011066 RP001011501 RP001011727 RP001011764 RP001012147 RP001012192 RP001012258 RP001012699 RP001015116 RP001015538 RP001015821 RP001015963 RP001016214 RP001017076 RP001017531 RP001018919 RP001018926 RP001019082 RP001019476 RP001020590 RP001020623 RP001021060 RP001021340 RP001022383 RP001022615 RP001022824 RP001022830 RP001023072 RP001023564 RP001023754 RP001023911 RP001024295 RP001024751 RP001024977 RP001025088 RP001025139 RP001025711 RP001025844 RP001026006 RP001026149 RP001026177 RP001026442 RP001026956 RP001027874 RP001028191 RP001028723 RP001029072 RP001031227 RP001031535 RP001031855 RP001032326 RP001032874 RP001033002 RP001033119 RP001033586 RP001033697 RP001034456 RP001034486 RP001036037 RP001037150 RP001037248 RP001038039 RP001038252 RP001038632 RP001038728 RP001038913 RP001039202 RP001039344 RP001039404 RP001039769 RP001039909 RP001040351 RP001041027 RP001041154 RP001042422 RP001042468 RP001042827 RP001042945 RP001043229 RP001043507 RP001043999 RP001044208 RP001044933 RP001045025 RP001045495 RP001045541 RP001046055 RP001046493 RP001046570 RP001046850 RP001046858 RP001047429 RP001047635 RP001047857 RP001047887 RP001047894 RP001050575 RP001050577 RP001050696 RP001052230 RP001052321 RP001052701 RP001053661 RP001054354 RP001054792 RP001055263 RP001055316 RP001055931 RP001056701 RP001056730 RP001056780 RP003021541 RP003135550 RP003171355 RP003269161 RP003278711 RP003302039 RP003319849 RP003431833 RP003500848 RP003553343 RP003569392 RP003608325
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0261403 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35486 45938
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Ogt BcDNA:GH04245 (Bayraktaroglu, 2000.8.7) Source for merge of: sxc l(2)NC130 (Gambetta et al., 2009) Source for merge of: sxc Ogt (Gambetta et al., 2009)
Additional comments	FlyBase Curator comment: Added "l(2)02637" symbol synonym to sxc as FBrf0209489 states that the lethality associated with the "l(2)02637" line is caused by a second lesion, the Transpac{}sxc[02637] insertion, in the sxc gene and not the P{PZ}L[02637] insertion in the L gene.
Other Comments
	Identification: During an EMS mutagenesis for lethal mutations uncovered by Df(2R)M41A8. (Myster et al., 2004) Mutant analysis demonstrates functional interactions between Pc, sxc and Asx in vivo. (Milne et al., 1999) In an effort to subdivide the Pc-group genes functionally, the phenotypes of adult flies heterozygous for every pairwise combination of Pc-group mutation were examined. Genetic interactions have been demonstrated between esc, Asx, E(Pc), Pcl, E(z) and sxc. Most duplications of Pc-group genes neither exhibit anterior transformations nor suppress the extra sex comb phenotype of Pc-group mutations, suggesting that not all Pc-group genes behave as predicted by the mass action model. (Campbell et al., 1995) Sections of the Scr regulatory region may be important for regulation of Scr by Polycomb- and trithorax-group genes. (Gindhart and Kaufman, 1995) The Pc group genes are negative regulators of homeotic genes. (McKeon and Brock, 1991)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078896 NM_165426 NM_165427 RefSeq (Proteins) • NP_523620 NP_724406 NP_724407 DDBJ / EMBL / GenBank • AA536259 AAD38597 AAF32311 AAF57338 AAF57338.1 AAG22338 AAG22338.1 AAG22339 AAG22339.1 AAL28773 AF145622 AF217788 AI064003 AI401949 AW942428 AY061225 Entrez Gene - A searchable database of RefSeq genes. • 35486 UniProtKB/TrEMBL • Q7KJA9 Q9Y148 Q95RP9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Tetratricopeptide-like helical (IPR011990) Tetratricopeptide repeat-containing (IPR013026) Tetratricopeptide repeat (IPR019734) Tetratricopeptide TPR-1 (IPR001440)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61400 DroID - A comprehensive database of gene and protein interactions. • FBgn0261403 DRSC - Results from RNAi screens. • FBgn0261403 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0261403 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0261403 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 35486 45938 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 35486 modMine - Data generated by the modENCODE project. • FBgn0261403 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17775 PB17773 PB17770 LH20126 ISCW016709 ISCW016010 ISCW011456 FBgn0229070 FBgn0223373 FBgn0207582 FBgn0189436 FBgn0178111 FBgn0166046 FBgn0250465 JGI_V11_324191 FBgn0249057 FBgn0150820 FBgn0141597 FBgn0129682 FBgn0129172 FBgn0108940 FBgn0091008 CPIJ004572 CPIJ004573 CPIJ004574 BGIBMGA011033 BGIBMGA000643 ACYPI006692 ACYPI004112 ACYPI002146 ACYPI001221 GB13441 AGAP006254 AAEL014746 AAEL012365 PHUM581590 GLEAN_03916
Synonyms & Secondary IDs ( 15 )
Reported As
Symbol Synonym	BcDNA:GH04245   CG10392 (Gambetta et al., 2009, Gambetta et al., 2009, Labourier et al., 2002, Rossi et al., 2007, Keleman et al., 2009.8.5) l(2)02637 (Jackle and Janning, 1998.8.10, Spradling et al., 1999) l(2)NC130 (Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009) Ogt (Gambetta et al., 2009, Badal et al., 2006, Stuart et al., 2007, Yasuhara and Wakimoto, 2008, Liu and Lehmann, 2008, Sinclair et al., 2009, Sinclair et al., 2009, Sekine et al., 2010) OGT (Jínek et al., 2004, Matsuura et al., 2008) P1201 (Dickson et al., 1995) sxc (Hirose et al., 2001, Gambetta et al., 2009, Gambetta and Mueller, 2009.8.18, Gambetta et al., 2009, Sinclair et al., 2009, Sinclair et al., 2009, Ashton-Beaucage et al., 2010) SXC (Schwartz and Pirrotta, 2007) Sxc (Gildea et al., 2000) sxc/Ogt (Gambetta et al., 2009, Gambetta and Mueller, 2009.8.18)
Name Synonym	lethal (2) NC130   O-glycosyltransferase (Rubenstein, 1999.12.20, Zhang et al., 2008) O-linked N-acetylglucosamine transferase (Gambetta et al., 2009) super sex combs (Gambetta et al., 2009, Sinclair et al., 2009)
Secondary FlyBase IDs
	FBan0010392 FBgn0003658 FBgn0027591 FBgn0040295 FBgn0067375 FBgn0261392
References ( 66 )
Generate a list of	All references relating to this gene ( 66 )
List References by type	Research paper  ( 39 ) Supplementary material  ( 5 ) Review  ( 7 ) Personal communication to FlyBase  ( 9 ) Abstract  ( 1 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Book  ( 1 ) Computer file  ( 1 ) Automatic genome annotation  ( 1 )
Recent research papers ( 2 )
	Ashton-Beaucage et al., 2010, Cell 143(2): 251--262 The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. [FBrf0212064] Sekine et al., 2010, J. Biol. Chem. 285(49): 38684--38691 Blocking O-Linked GlcNAc Cycling in Drosophila Insulin-producing Cells Perturbs Glucose-Insulin Homeostasis. [FBrf0212389] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...