Ogt, O-GlcNAc transferase, l(2)NC130, l(2)02637, sxc/Ogt
Please see the JBrowse view of Dmel\sxc for information on other features
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Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.47
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sxc using the Feature Mapper tool.
Comment: maternally deposited
GBrowse - Visual display of RNA-Seq signals
View Dmel\sxc in GBrowse 22-55
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Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: sxc l(2)NC130
Source for merge of: Ogt BcDNA:GH04245
Source for merge of: sxc Ogt
FlyBase Curator comment: Added "l(2)02637" symbol synonym to sxc as FBrf0209489 states that the lethality associated with the "l(2)02637" line is caused by a second lesion, the Transpac{}sxc02637 insertion, in the sxc gene and not the P{PZ}L02637 insertion in the L gene.
Identification: During an EMS mutagenesis for lethal mutations uncovered by Df(2R)M41A8.
In an effort to subdivide the Pc-group genes functionally, the phenotypes of adult flies heterozygous for every pairwise combination of Pc-group mutation were examined. Genetic interactions have been demonstrated between esc, Asx, E(Pc), Pcl, E(z) and sxc. Most duplications of Pc-group genes neither exhibit anterior transformations nor suppress the extra sex comb phenotype of Pc-group mutations, suggesting that not all Pc-group genes behave as predicted by the mass action model.
The Pc group genes are negative regulators of homeotic genes.