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Gene Dmel\sgl

General Information
Symbol	Dmel\sgl	Species	D. melanogaster
Name	sugarless	Annotation symbol	CG10072
Feature type	protein_coding_gene	FlyBase ID	FBgn0261445
Gene Model Status	Current	Stock availability	22 publicly available
Also Known As	kiwi, ska, UDPGDH, UDP-GlcDH
Genomic Location
Chromosome (arm)	3L	Recombination map	3-22.2
Cytogenetic map	65D4-65D5	Sequence location	3L:6,952,647..6,957,902 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene sugarless is referred to in FlyBase by the symbol Dmel\sgl (CG10072, FBgn0261445). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: UDP-glucose 6-dehydrogenase activity. There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; olfactory behavior; mushroom body development; segment polarity determination. 41 alleles are reported. The phenotypes of these alleles are annotated with: organ system; organ system subdivision; multicellular structure; adult segment; tracheal system; acellular anatomical structure; portion of tissue; adult; sense organ; imaginal precursor. It has one annotated transcript and one annotated polypeptide. Protein features are: 6-phosphogluconate dehydrogenase, C-terminal-like; Cytochrome c1, transmembrane anchor, C-terminal; NAD(P)-binding domain; Nucleotide sugar dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, adult heart, larval fat body, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1629352_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of sgl. Gene sequence location is 3L:6952647..6957902.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Carreira et al., 2011, BMC Dev. Biol. 11: 32 Jumbo-Lucioni et al., 2010, BMC Genomics 11: 297 Sotillos et al., 2010, Dev. Biol. 340(2): 571--582 Zwarts et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(41): 17070--17075 Sequence features BKN45363
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 65D4-65D5   Limits computationally determined from genome sequence between P{lacW}l(3)L4060L4060 and P{PZ}corn04202
Experimentally Determined Cytological Location
Cytogenetic map Notes References 65D-65D   (determined by in situ hybridisation)   (Weber, 2005) 64A-64A     (Haerry, 1997.6.11) 65D4-65D5     (Haecker, 1997.6.17) 65D4-65D6     (Benevolenskaya, 1997.4.25) 65D4-65D5   (determined by in situ hybridisation)   (Spradling et al., 1999) 65D4-65D5   (determined by in situ hybridisation)   (Perrimon et al., 1996) 65D4-65D5   65D4--6   (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location	3-22.2
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\sgl for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	DGC clone GH20839 appears problematic: incomplete CDS
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) sgl-RA FBtr0076938  NM_057632   2326   476
Additional Transcript Data & Comments
Reported size (kB)	2.4 (northern blot) (Binari et al., 1997) 2.3 (northern blot) (Haerry et al., 1997, Hacker et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein sgl-PA   FBpp0076647   52.9   476   6.08     NP_476980   AAF50631
Additional Polypeptide Data & Comments
Reported size (kDa)	476 (aa); 53 (kD predicted) (Haerry et al., 1997) 476 (aa) (Hacker et al., 1997, Binari et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • UDP-glucose/GDP-mannose dehydrogenase, N-terminal (IPR001732) 6-phosphogluconate dehydrogenase, C-terminal-like (IPR008927) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (IPR014026) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (IPR014027) NAD(P)-binding domain (IPR016040) Nucleotide sugar dehydrogenase (IPR017476) Cytochrome c1, transmembrane anchor, C-terminal (IPR021157)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263466   AA942506   AE014296 AAF50631   AC004351   AF000570 AAB58714   AF001310 AAC97125   AF001311 AAC97126   AF001312 AAC97126   AF007870 AAB63208   AF009013 AAB63462   AI386687   AI389619   AI389629   AI531405   AI532838   AI534636   AI542954   AQ073032   AW940795   AY052137 AAK93561   AY060756 AAL28304   BF506270   BG636332   BG636500   BH023800   BI173218   BI213106   BI215771   BI227563   BI229247   BI232980   BI234541   BI236081   BI238950   BI239137   BI239447   BI242548   BI366981   BI367630   BI376170   BI376185   BI487254   BI487256   BI581132   BI581134   BI581142   BI618799   BI638056   BI638065   BI638066   CL632150   CO155139   CO156601   CO176841   CO185988   CO194249   CO194713   CO287999   CO290084   CO303457   CO304944   CO320913   CO323387   CO323388   CO333432   CO336327   CO337972   CZ468344   CZ468448   CZ468449   CZ473071   CZ476906   EC058137   EC060267   EC070291   EC090747   EC204783   EC223614   EC226391   EC229247   EC235083   EC235174   EC237760   EC250159   EC262323   EC263837   EV583326   FE862640   FE862674   FE863157   FE863197   FE863226   G00549
UniProtKB/Swiss-Prot	O02373
UniProtKB/TrEMBL	Q95SJ7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
No Assay Recorded Stage Tissue/Position (including subcellular localization) Reference embryonic stage     (Hacker et al., 1997) in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage | early     (Haerry et al., 1997) embryonic stage 1 -- 3   organism | ubiquitous   (Binari et al., 1997) extended germ band stage   mesoderm   (Haerry et al., 1997) embryonic stage 9 -- 14   amnioserosa | presumptive   (Binari et al., 1997) embryonic stage 10 -- 17   cephalic furrow | surrounding   (Binari et al., 1997) embryonic stage 13   embryonic/larval midgut   (Haerry et al., 1997) embryonic stage 16 -- 17   embryonic/larval proventriculus   (Haerry et al., 1997) embryonic/larval hindgut   (Haerry et al., 1997) embryonic stage 17   embryonic/larval pharynx   (Haerry et al., 1997) third instar larval stage   morphogenetic furrow   (Haerry et al., 1997) imaginal disc   (Haerry et al., 1997)
Additional Descriptive Data
	sgl transcript is found in the early embryo. After germ band extension, signal is more intense in the mesoderm. After germ band retraction, sgl is expressed in the midgut. After dorsal closure, sgl expression is detected in the pharynx and hindgut. sgl is detected ubiquitously in most third instar larval imaginal discs. Low levels of sgl are detected in the eye imaginal disc, with the highest concentration found in the morphogenetic furrow. (Haerry et al., 1997) sgl transcript is distributed uniformly in the embryo before stage 4. By stage 9, sgl expression has become restricted to the areas surrounding the cephalic furrow, and the presumptive amnioserosa. Expression in the amnioserosa persists at least until stage 14 of embryogenesis. (Binari et al., 1997) sgl is expressed both maternally and ubiquitously throughout embryonic development. (Hacker et al., 1997)
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0261445    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0261445 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0261445 expression level Developmental Stage   Expression Level embryo 00-02hr    4355 embryo 02-04hr    3426 embryo 04-06hr    2871 embryo 06-08hr    3691 embryo 08-10hr    3894 embryo 10-12hr    4590 embryo 12-14hr    3615 embryo 14-16hr    4258 embryo 16-18hr    3992 embryo 18-20hr    4742 embryo 20-22hr    3454 embryo 22-24hr    3654 larva L1    2540 larva L2    2999 larva L3 12hr old    1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6    1931 larva L3 puffstage 7-9    4459 white prepupae new    5839 white prepupae 12hr    1650 white prepupae 24hr    1909 pupae 2d postWPP    1868 pupae 3d postWPP    1671 pupae 4d postWPP    1770 adult male 01day    1452 adult male 05day    1700 adult male 30day    2040 adult female 01day    3031 adult female 05day    3232 adult female 30day    3319 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4355) embryo 02-04hr  (3426) embryo 04-06hr  (2871) embryo 06-08hr  (3691) embryo 08-10hr  (3894) embryo 10-12hr  (4590) embryo 12-14hr  (3615) embryo 14-16hr  (4258) embryo 16-18hr  (3992) embryo 18-20hr  (4742) embryo 20-22hr  (3454) embryo 22-24hr  (3654) larva L1  (2540) larva L2  (2999) larva L3 12hr old  (1736) larva L3 puffstage 1-2  (1235) larva L3 puffstage 3-6  (1931) larva L3 puffstage 7-9  (4459) white prepupae new  (5839) white prepupae 12hr  (1650) white prepupae 24hr  (1909) pupae 2d postWPP  (1868) pupae 3d postWPP  (1671) pupae 4d postWPP  (1770) adult male 01day  (1452) adult male 05day  (1700) adult male 30day  (2040) adult female 01day  (3031) adult female 05day  (3232) adult female 30day  (3319) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4355) embryo 02-04hr  (3426) embryo 04-06hr  (2871) embryo 06-08hr  (3691) embryo 08-10hr  (3894) embryo 10-12hr  (4590) embryo 12-14hr  (3615) embryo 14-16hr  (4258) embryo 16-18hr  (3992) embryo 18-20hr  (4742) embryo 20-22hr  (3454) embryo 22-24hr  (3654) larva L1  (2540) larva L2  (2999) larva L3 12hr old  (1736) larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6  (1931) larva L3 puffstage 7-9  (4459) white prepupae new  (5839) white prepupae 12hr  (1650) white prepupae 24hr  (1909) pupae 2d postWPP  (1868) pupae 3d postWPP  (1671) pupae 4d postWPP  (1770) adult male 01day  1452 adult male 05day  (1700) adult male 30day  (2040) adult female 01day  (3031) adult female 05day  (3232) adult female 30day  (3319) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4355 embryo 02-04hr    3426 embryo 04-06hr    2871 embryo 06-08hr    3691 embryo 08-10hr    3894 embryo 10-12hr    4590 embryo 12-14hr    3615 embryo 14-16hr    4258 embryo 16-18hr    3992 embryo 18-20hr    4742 embryo 20-22hr    3454 embryo 22-24hr    3654 larva L1    2540 larva L2    2999 larva L3 12hr old    1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6    1931 larva L3 puffstage 7-9    4459 white prepupae new    5839 white prepupae 12hr    1650 white prepupae 24hr    1909 pupae 2d postWPP    1868 pupae 3d postWPP    1671 pupae 4d postWPP    1770 adult male 01day    1452 adult male 05day    1700 adult male 30day    2040 adult female 01day    3031 adult female 05day    3232 adult female 30day    3319 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4355 embryo 02-04hr    3426 embryo 04-06hr    2871 embryo 06-08hr    3691 embryo 08-10hr    3894 embryo 10-12hr    4590 embryo 12-14hr    3615 embryo 14-16hr    4258 embryo 16-18hr    3992 embryo 18-20hr    4742 embryo 20-22hr    3454 embryo 22-24hr    3654 larva L1    2540 larva L2    2999 larva L3 12hr old    1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6    1931 larva L3 puffstage 7-9    4459 white prepupae new    5839 white prepupae 12hr    1650 white prepupae 24hr    1909 pupae 2d postWPP    1868 pupae 3d postWPP    1671 pupae 4d postWPP    1770 adult male 01day    1452 adult male 05day    1700 adult male 30day    2040 adult female 01day    3031 adult female 05day    3232 adult female 30day    3319 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0261445 expression level Developmental Stage   Expression Level embryo 00-02hr    4355 embryo 02-04hr    3426 embryo 04-06hr    2871 embryo 06-08hr    3691 embryo 08-10hr    3894 embryo 10-12hr    4590 embryo 12-14hr    3615 embryo 14-16hr    4258 embryo 16-18hr    3992 embryo 18-20hr    4742 embryo 20-22hr    3454 embryo 22-24hr    3654 larva L1    2540 larva L2    2999 larva L3 12hr old    1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6    1931 larva L3 puffstage 7-9    4459 white prepupae new    5839 white prepupae 12hr    1650 white prepupae 24hr    1909 pupae 2d postWPP    1868 pupae 3d postWPP    1671 pupae 4d postWPP    1770 adult male 01day    1452 adult male 05day    1700 adult male 30day    2040 adult female 01day    3031 adult female 05day    3232 adult female 30day    3319 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4355) embryo 02-04hr  (3426) embryo 04-06hr  (2871) embryo 06-08hr  (3691) embryo 08-10hr  (3894) embryo 10-12hr  (4590) embryo 12-14hr  (3615) embryo 14-16hr  (4258) embryo 16-18hr  (3992) embryo 18-20hr  (4742) embryo 20-22hr  (3454) embryo 22-24hr  (3654) larva L1  (2540) larva L2  (2999) larva L3 12hr old  (1736) larva L3 puffstage 1-2  (1235) larva L3 puffstage 3-6  (1931) larva L3 puffstage 7-9  (4459) white prepupae new  (5839) white prepupae 12hr  (1650) white prepupae 24hr  (1909) pupae 2d postWPP  (1868) pupae 3d postWPP  (1671) pupae 4d postWPP  (1770) adult male 01day  (1452) adult male 05day  (1700) adult male 30day  (2040) adult female 01day  (3031) adult female 05day  (3232) adult female 30day  (3319) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4355) embryo 02-04hr  (3426) embryo 04-06hr  (2871) embryo 06-08hr  (3691) embryo 08-10hr  (3894) embryo 10-12hr  (4590) embryo 12-14hr  (3615) embryo 14-16hr  (4258) embryo 16-18hr  (3992) embryo 18-20hr  (4742) embryo 20-22hr  (3454) embryo 22-24hr  (3654) larva L1  (2540) larva L2  (2999) larva L3 12hr old  1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6  1931 larva L3 puffstage 7-9  (4459) white prepupae new  (5839) white prepupae 12hr  1650 white prepupae 24hr  1909 pupae 2d postWPP  1868 pupae 3d postWPP  1671 pupae 4d postWPP  1770 adult male 01day  1452 adult male 05day  1700 adult male 30day  2040 adult female 01day  (3031) adult female 05day  (3232) adult female 30day  (3319) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4355 embryo 02-04hr    3426 embryo 04-06hr    2871 embryo 06-08hr    3691 embryo 08-10hr    3894 embryo 10-12hr    4590 embryo 12-14hr    3615 embryo 14-16hr    4258 embryo 16-18hr    3992 embryo 18-20hr    4742 embryo 20-22hr    3454 embryo 22-24hr    3654 larva L1    2540 larva L2    2999 larva L3 12hr old    1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6    1931 larva L3 puffstage 7-9    4459 white prepupae new    5839 white prepupae 12hr    1650 white prepupae 24hr    1909 pupae 2d postWPP    1868 pupae 3d postWPP    1671 pupae 4d postWPP    1770 adult male 01day    1452 adult male 05day    1700 adult male 30day    2040 adult female 01day    3031 adult female 05day    3232 adult female 30day    3319 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4355 embryo 02-04hr    3426 embryo 04-06hr    2871 embryo 06-08hr    3691 embryo 08-10hr    3894 embryo 10-12hr    4590 embryo 12-14hr    3615 embryo 14-16hr    4258 embryo 16-18hr    3992 embryo 18-20hr    4742 embryo 20-22hr    3454 embryo 22-24hr    3654 larva L1    2540 larva L2    2999 larva L3 12hr old    1736 larva L3 puffstage 1-2    1235 larva L3 puffstage 3-6    1931 larva L3 puffstage 7-9    4459 white prepupae new    5839 white prepupae 12hr    1650 white prepupae 24hr    1909 pupae 2d postWPP    1868 pupae 3d postWPP    1671 pupae 4d postWPP    1770 adult male 01day    1452 adult male 05day    1700 adult male 30day    2040 adult female 01day    3031 adult female 05day    3232 adult female 30day    3319 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0261445    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0261445 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult salivary gland. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult hindgut, adult heart, larval fat body, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0261445 expression level Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut    1275.7 Larval Hindgut    835.7 Larval Malpighian Tubules    1408.7 Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut    861.6 Adult Hindgut    366.3 Adult Malpighian Tubules    1633.8 Adult Fat Body    86.7 Adult Salivary Gland    3806.2 Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut  (1275.7) Larval Hindgut  (835.7) Larval Malpighian Tubules  (1408.7) Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut  (861.6) Adult Hindgut    366.3 Adult Malpighian Tubules  (1633.8) Adult Fat Body    86.7 Adult Salivary Gland  (3806.2) Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut  (1275.7) Larval Hindgut    835.7 Larval Malpighian Tubules  (1408.7) Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut    861.6 Adult Hindgut    366.3 Adult Malpighian Tubules  (1633.8) Adult Fat Body    86.7 Adult Salivary Gland  (3806.2) Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut    1275.7 Larval Hindgut    835.7 Larval Malpighian Tubules    1408.7 Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut    861.6 Adult Hindgut    366.3 Adult Malpighian Tubules    1633.8 Adult Fat Body    86.7 Adult Salivary Gland    3806.2 Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0261445 expression level Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut    1275.7 Larval Hindgut    835.7 Larval Malpighian Tubules    1408.7 Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut    861.6 Adult Hindgut    366.3 Adult Malpighian Tubules    1633.8 Adult Fat Body    86.7 Adult Salivary Gland    3806.2 Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut  (1275.7) Larval Hindgut  (835.7) Larval Malpighian Tubules  (1408.7) Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut  (861.6) Adult Hindgut    366.3 Adult Malpighian Tubules  (1633.8) Adult Fat Body    86.7 Adult Salivary Gland  (3806.2) Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut  1275.7 Larval Hindgut    835.7 Larval Malpighian Tubules  1408.7 Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut    861.6 Adult Hindgut    366.3 Adult Malpighian Tubules  1633.8 Adult Fat Body    86.7 Adult Salivary Gland  (3806.2) Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    354.625 Larval Midgut    1275.7 Larval Hindgut    835.7 Larval Malpighian Tubules    1408.7 Larval Fat Body    321.3 Larval Salivary Gland    14.2 Larval Trachea    135.075 Larval Carcass    228.125 Adult Head    190.6 Adult Eye    168.725 Adult Brain    287.2 Adult Thoracic-Abdominal Ganglion    295.9 Adult Crop    290.3 Adult Midgut    861.6 Adult Hindgut    366.3 Adult Malpighian Tubules    1633.8 Adult Fat Body    86.7 Adult Salivary Gland    3806.2 Adult Heart    198.95 Adult VirginFemale Spermatheca    465 Adult InseminatedFemale Spermatheca    437.9 Adult Ovary    422.3 Adult Testis    38.3 Adult Male Accessory Gland    124.2 Adult Carcass    98.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    190.6   NA  Eye    168.725   NA  Brain    287.2   354.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    295.9   NA  Crop    290.3   1275.7  Midgut    861.6   835.7  Hindgut    366.3   1408.7  Malpighian Tubules    1633.8   321.3  Fat Body    86.7   14.2  Salivary Gland    3806.2   NA  Heart    198.95   135.075  Trachea    NA   NA  VirginFemale Spermatheca    465   NA  InseminatedFemale Spermatheca    437.9   NA  Ovary    422.3   NA  Testis    38.3   NA  Male Accessory Gland    124.2   228.125  Carcass    98.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0261445
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | embryonic stage | partially | rescuable maternal effect sgl08310 lethal | larval stage | recessive sgl08310 lethal | partially | recessive | rescuable maternal effect | segment polarity expression pattern sgl08310 lethal | recessive sgl08310 sgl10503 sglA31 sglj3E11 sglN71 sglSG9 semi-lethal sgl05007 semi-lethal | recessive sgl05007 viable sglCB05101 sglEY04671 sglW27 viable, with Scer\GAL4pnr-MD237 sglGD14861 Sterility Allele fertile sglEY04671 Other Phenotypes Allele behavior defective | recessive sglBG01214 chemical resistant, with Scer\GAL4da.G32 sglUY771 visible | somatic clone sgl08310 wild-type sgl51b sglUbi-p63E.PH Phenotype manifest in Allele cuticle sgl08310 denticle belt sgl08310 denticle belt | germline clone sgl08310 embryo | germline clone | segment polarity expression pattern sgl08310 embryonic/first instar larval cuticle sgl08310 embryonic/first instar larval cuticle | dorsal sgl08310 embryonic/first instar larval cuticle | germline clone sgl08310 embryonic/larval dorsal trunk sgl08310 embryonic/larval ganglionic branch sgl08310 embryonic/larval lateral trunk sgl08310 embryonic/larval tracheal system sgl08310 embryonic/larval tracheal system | germline clone sgl08310 embryonic Malpighian tubule | germline clone sgl08310 eye-antennal disc sglA31 sglSG9 imaginal disc | larval stage sglSG9 imaginal disc | P-stage sglSG9 macrochaeta sglBG01914 mesoderm | germline clone sgl08310 midgut constriction 2 | germline clone sgl08310 mushroom body alpha'-lobe sglBG01214 mushroom body alpha-lobe sglBG01214 mushroom body beta'-lobe sglBG01214 mushroom body beta-lobe sglBG01214 segment | ventral sgl08310 stomodeal invagination | germline clone sgl08310 wing sglW27 wing | somatic clone sgl08310 wing margin bristle | somatic clone sgl08310
Classical Alleles ( 36 )
For All Classical Alleles Show
Allele of sgl Class Mutagen Stocks Known lesion sglA31 ethyl methanesulfonate 2 -- sglBG02666 P-element activity 2 -- sgl08310 loss of function allele P-element activity 1 Yes sgl5-HA-1090 1 -- sgl5-HA-1091 1 -- sgl5-HA-1209 1 -- sgl5-HA-1605 1 -- sglc02874 1 -- sglc02940 piggyBac transposase 1 -- sglCB-6278-3 1 -- sgld02925 P-element activity 1 -- sgld09725 P-element activity 1 -- sglEY04671 P-element activity 1 -- sglNP2030 1 -- sglNP3616 1 -- sglNP6660 1 -- sglSG9 hypomorphic allele - genetic evidence ethyl methanesulfonate 1 -- sglUM-8091-3 1 -- sglUY771 P-element activity 1 Yes sgl05007 P-element activity 0 Yes sgl10503 P-element activity 0 Yes sglBG01214 0 -- sglBG01914 P-element activity 0 Yes sglc03125 piggyBac transposase 0 -- sglCB05101 P-element activity 0 Yes sgld05356 0 -- sglEP3579 P-element activity 0 -- sglEX34 X ray 0 -- sglG126 P-element activity 0 Yes sglj3E11 P-element activity 0 -- sglN71 ethyl methanesulfonate 0 -- sglNP4753 0 -- sgls2466a P-element activity 0 -- sglunspecified 0 -- sglW27 P-element activity 0 Yes sglXAJ36 X ray 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of sgl Class Mutagen Stocks Known lesion sglGD14861 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes sgl51b in vitro construct - genomic fragment 0 Yes sgldsRNA.cLa in vitro construct - RNAi 0 Yes sglfl.cHa in vitro construct 0 Yes sglUbi-p63E.PH in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)BSC27 (Deal et al., 2002.12.17) Df(3L)vvl7247-Mis12 (Sotillos et al., 2010) Df(3L)W5.4 (Hacker et al., 1997, Anderson et al., 1995, Benevolenskaya et al., 1998)
Not disrupted in	Df(3L)XAS96 (Anderson et al., 1995) Df(3L)XBB70 (Anderson et al., 1995) Df(3L)ZN47 (BDGP Project Members, 1994-1999, Spradling et al., 1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14861} NA characterization construct P{ubi-ska} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}sglEP3579 NA P{EPgy2}sglEY04671 NA P{Mae-UAS.6.11}sglUY771 NA P{XP}sgld02925 NA P{XP}sgld05356 NA P{XP}sgld09725 NA miscellaneous insertions P{Ecol\lacO.256x.w}P2.5 NA P{GT1}sglBG01214 NA P{GT1}sglBG01914 NA P{GT1}sglBG02666 NA P{PTT-GB}sglCB05101 NA P{PTT-GB}sglG126 NA P{RS3}sglCB-6278-3 NA P{RS3}sglUM-8091-3 NA P{RS5}sgl5-HA-1090 NA P{RS5}sgl5-HA-1091 NA P{RS5}sgl5-HA-1209 NA P{RS5}sgl5-HA-1605 NA PBac{PB}sglc02874 NA PBac{PB}sglc02940 NA PBac{PB}sglc03125 NA insertion of enhancer trap binary system P{GawB}sglNP2030 No P{GawB}sglNP3616 No P{GawB}sglNP4753 No P{GawB}sglNP6660 No insertion of enhancer trap P{lacW}sglj3E11 No P{lacW}sgls2466a No P{lacW}sglW27 No P{PZ}sgl05007 No P{PZ}sgl08310 No P{PZ}sgl10503 No
Gene Ontology: Function, Process & Cellular Component ( 19 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
inter-male aggressive behavior inferred from mutant phenotype (Edwards et al., 2009) mushroom body development inferred from mutant phenotype (Edwards et al., 2009) olfactory behavior inferred from mutant phenotype (Sambandan et al., 2006) segment polarity determination inferred from mutant phenotype (Perrimon et al., 1996, Zhu et al., 2005)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 15 terms )
Molecular Function
CV term Evidence References
NAD binding inferred from electronic annotation with InterPro:IPR001732, InterPro:IPR014026, InterPro:IPR014027, InterPro:IPR017476 (FlyBase Curators et al., 2004-) UDP-glucose 6-dehydrogenase activity inferred from sequence or structural similarity (Lin et al., 1997) inferred from sequence or structural similarity with EMBL:AB013732 (FlyBase, 1992-) non-traceable author statement (Haerry et al., 1997, Benevolenskaya, 1997.4.25) traceable author statement (Ghabrial et al., 2003)
Biological Process
CV term Evidence References
cell surface receptor linked signaling pathway non-traceable author statement (Cripps and Olson, 2002) chondroitin sulfate biosynthetic process traceable author statement (Nybakken and Perrimon, 2002) epithelial cell migration, open tracheal system traceable author statement (Affolter and Shilo, 2000) fibroblast growth factor receptor signaling pathway traceable author statement (Ghabrial et al., 2003) glycosaminoglycan biosynthetic process non-traceable author statement (Swiss-Prot Project Members, 1998.12.15) heart development non-traceable author statement (Nybakken and Perrimon, 2002) heparan sulfate proteoglycan biosynthetic process traceable author statement (Park et al., 2000, Ghabrial et al., 2003) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process non-traceable author statement (Perrimon and Bernfield, 2000) mesoderm migration involved in gastrulation traceable author statement (Cripps and Olson, 2002) oxidation-reduction process inferred from electronic annotation with InterPro:IPR001732, InterPro:IPR008927, InterPro:IPR014026, InterPro:IPR014027, InterPro:IPR017476 (FlyBase Curators et al., 2004-) primary branching, open tracheal system traceable author statement (Ghabrial et al., 2003) smoothened signaling pathway traceable author statement (Nybakken and Perrimon, 2002) Wnt receptor signaling pathway traceable author statement (Nybakken and Perrimon, 2002)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene (Sambandan et al., 2006) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions sgl allele Gene References sgl05007 w (Benevolenskaya et al., 1998) wg (Moline et al., 2000) sgl08310 bnl (Lin et al., 1999) dally (Tsuda et al., 1999) dsh (Haerry et al., 1997) htl (Lin et al., 1999) sglN71 dally (Tsuda et al., 1999) sglSG9 dsh (Haerry et al., 1997) unspecified hh (Benevolenskaya et al., 1998) wg (Haerry et al., 1997, Benevolenskaya et al., 1998)
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0261445 DroID - A comprehensive database of gene and protein interactions. • FBgn0261445 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38760
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10882 Dere\GG15016 Dgri\GH16103 Dmoj\GI12367 Dper\GL15063 Dpse\GA10050 Dsec\GM13805 Dsim\GD13103 Dvir\GJ12259 Dwil\GK17198 Dyak\GE20458
Curated drosophilid orthologs	Dpse\GA10050
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18892 NV17389 LH21840 ISCW009911 FBgn0237773 FBgn0219197 FBgn0199509 FBgn0184825 FBgn0168736 JGI_V11_306816 FBgn0070109 FBgn0152667 FBgn0135124 FBgn0123574 FBgn0107270 FBgn0087922 CPIJ002992 BGIBMGA012188 ACYPI008175 GB15000 AGAP006532 AAEL011242 PHUM527160 GLEAN_03239
Stocks & Reagents
Stocks Listed in FlyBase ( 22 )
Harvard	- P{XP}sgld02925 - P{XP}sgld09725 - PBac{PB}sglc02874 - PBac{PB}sglc02940
Kyoto	113374 w*; P{GawB}sglNP3616 124016 w1118; P{RS3}sglCB-6278-3 124333 w1118; P{RS3}sglUM-8091-3 125063 w1118; P{RS5}sgl5-HA-1090 125064 w1118; P{RS5}sgl5-HA-1091 125142 w1118; P{RS5}sgl5-HA-1209 125292 w1118; P{RS5}sgl5-HA-1605
VDRC	v29434 w1118; P{GD14861}v29434
	More stocks available...
Genomic Clones ( 1 )
	BACR14L10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 74 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH20839 SD09476
Other clones	DPiM_SD09476
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08708 GH16851 GH20852 LD07210 LD26758 RE15984 RE18433 RE22374 RE24647 RE26991 RE29240 RE30257 RE32078 RE35326 RE35545 RE35932 RE39921 RE52639 RE53433 RE59261 RE63712 RE69708 RE70358 RE72716 RE72868 RE73287 RH49714 SD02427 SD04469 SD07557 SD14229 SD18355 SD19013 SD19037
Other clones	5206 63579 63643 64893 124458 147814 172621 183960 281561 524468 557743 CK01.22B.G7 CK01.63C.G3 CK01.93D.F11 Dmel_dig_018700_0627_2811 EC37692 EC39092 EK014903 EK051326 EK067509 EK073024 EK190351 EK190352 EK241607 EK246760 EK288749 EK306926 EN05442 EN08402 EN12320 EN15706 RM05425 RM06125 RM06225 RM06425 RM06525 SD13971
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0261445 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38760
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: sgl CG10072 (Gabrielian, 1999.11)
Source for database merge of	Source for merge of: sgl BG01214 (Edwards et al., 2009)
Additional comments	"kiwi" has been used as a valid symbol for FBgn0020295 and as a synonym for sgl, FBgn0010851.
Other Comments
	Loss of both maternal and zygotic sgl function results in profound defects in mesoderm and tracheal cell migration in the embryo. (Lin et al., 1999) The levels of glycosaminoglycans (in which sgl plays a role) are rate limiting for cell-cell signalling pathways such as those of wg and hh, which mediate changes in gene expression. (Benevolenskaya et al., 1998) Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland. (Harvie et al., 1998) sgl has been cloned and sequenced. sgl encodes UDP-glucose dehydrogenase and is required for efficient wg function. (Binari et al., 1997) sgl mutations impair signaling by wg protein. (Hacker et al., 1997) sgl mutants lack UDP-glucose dehydrogenase activity. (Haerry et al., 1997) sgl mutants lack glycosaminoglycan chains on proteoglycans. (Haerry et al., 1997) Identified by a P-element mutation with a cuticle phenotype similar to that of wg null alleles. (Lin et al., 1997) The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation. (Perrimon et al., 1996)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_057632 RefSeq (Proteins) • NP_476980 DDBJ / EMBL / GenBank • AA263466 AAB58714 AAB63208 AAB63462 AAC97125 AAC97126 AAF50631 AAK93561 AAL28304 AC004351 AF000570 AF001310 AF001311 AF001312 AF007870 AF009013 AI389619 AI542954 AQ073032 AW940795 AY052137 AY060756 BH023800 CL632150 CZ468344 CZ468448 CZ468449 CZ473071 CZ476906 G00549 Entrez Gene - A searchable database of RefSeq genes. • 38760 UniProtKB/Swiss-Prot • O02373 UniProtKB/TrEMBL • Q95SJ7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • UDP-glucose/GDP-mannose dehydrogenase, N-terminal (IPR001732) 6-phosphogluconate dehydrogenase, C-terminal-like (IPR008927) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (IPR014026) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (IPR014027) NAD(P)-binding domain (IPR016040) Nucleotide sugar dehydrogenase (IPR017476) Cytochrome c1, transmembrane anchor, C-terminal (IPR021157)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0261445 DroID - A comprehensive database of gene and protein interactions. • FBgn0261445 DRSC - Results from RNAi screens. • FBgn0261445 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0261445 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0261445 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38760 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38760 modMine - Data generated by the modENCODE project. • FBgn0261445 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB18892 NV17389 LH21840 ISCW009911 FBgn0237773 FBgn0219197 FBgn0199509 FBgn0184825 FBgn0168736 JGI_V11_306816 FBgn0070109 FBgn0152667 FBgn0135124 FBgn0123574 FBgn0107270 FBgn0087922 CPIJ002992 BGIBMGA012188 ACYPI008175 GB15000 AGAP006532 AAEL011242 PHUM527160 GLEAN_03239
Synonyms & Secondary IDs ( 24 )
Reported As
Symbol Synonym	8310 (Harvie et al., 1998) BG01214 (Sambandan et al., 2006) CG10072 (Norga et al., 2003, Monnier et al., 2002, Krejcí et al., 2009) kiwi (Wilson, 2004, Princivalle and de Agostini, 2002, Manoukian, 1997.4.22, Dale, 1998, Binari et al., 1997, ) l(3)65CEd   l(3)05007   l(3)08310   l(3)10503   l(3)SG9 (Lindsley and Zimm, 1992, ) sgl (Jordan et al., 2005, Buszczak et al., 2007, Zhu et al., 2007, Liebl et al., 2006, Lujan et al., 2008, Bornemann et al., 2008, Krejcí et al., 2009, Gim et al., 2001, Morozova et al., 2007, Yan et al., 2010) Sgl (Jumbo-Lucioni et al., 2010) ska (Princivalle and de Agostini, 2002, Haerry, 1997.6.11, Dale, 1998, Haerry et al., 1997, Haerry et al., 1997, ) sl (Lin et al., 1997) UDPGDH (Heslip et al., 2001, Heslip and Marsh, 2000, Benevolenskaya, 1997.4.25, Benevolenskaya, 1997.4.25, ) UDP-GlcDH (Scanga et al., 2001, Scanga and Manoukian, 1999) unnamed (Perrimon, 1997) XIII (Anderson et al., 1995)
Name Synonym	Distal W5.4 Group XIII (Anderson et al., 1995) kiwi (Cumberledge and Reichsman, 1997) lethal(3)SG9   sugarless (Jordan et al., 2005, Strigini and Cohen, 2000, Lin et al., 1997, Sambandan et al., 2006, Lujan et al., 2008, Torroja et al., 2005, Bornemann et al., 2008, Krejcí et al., 2009, Mensch et al., 2008, Edwards et al., 2009, Morozova et al., 2007, Yan et al., 2010) Sugarless (Gim et al., 2001) suppenkasper (Cumberledge and Reichsman, 1997, Wilson, 2004, Princivalle and de Agostini, 2002, Haerry et al., 1997, Haerry et al., 1997, ) UDP-glucose 6-dehydrogenase   UDP-glucose dehydrogenase (Nohynek et al., 1999)
Secondary FlyBase IDs
	FBgn0002456 FBgn0010851 FBgn0010929 FBgn0015500 FBgn0086381
References ( 114 )
Generate a list of	All references relating to this gene ( 114 )
List References by type	Research paper  ( 42 ) Supplementary material  ( 2 ) Review  ( 29 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 16 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 5 ) Book  ( 1 ) Curated genome annotation  ( 2 ) Computer file  ( 4 ) Protein sequence record  ( 1 ) Automatic genome annotation  ( 1 ) Letter  ( 1 )
Recent research papers ( 6 )
	Carreira et al., 2011, BMC Dev. Biol. 11: 32 Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273] Morozova et al., 2011, Genetics 187(4): 1193--1205 Transcriptional networks for alcohol sensitivity in Drosophila melanogaster. [FBrf0214377] Zwarts et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(41): 17070--17075 Complex genetic architecture of Drosophila aggressive behavior. [FBrf0216413] Jumbo-Lucioni et al., 2010, BMC Genomics 11: 297 Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. [FBrf0210956] Sotillos et al., 2010, Dev. Biol. 340(2): 571--582 An efficient approach to isolate STAT regulated enhancers uncovers STAT92E fundamental role in Drosophila tracheal development. [FBrf0210508] Yan et al., 2010, Development 137(12): 2033--2044 The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development. [FBrf0210906] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...