kiwi, suppenkasper, ska, UDPGDH, UDP-GlcDH
Please see the JBrowse view of Dmel\sgl for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
2.4 (northern blot)
2.3 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
476 (aa)
476 (aa); 53 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sgl using the Feature Mapper tool.
Comment: maternally deposited
Comment: reported as plasmatocytes anlage
sgl is expressed both maternally and ubiquitously throughout embryonic development.
sgl transcript is found in the early embryo. After germ band extension, signal is more intense in the mesoderm. After germ band retraction, sgl is expressed in the midgut. After dorsal closure, sgl expression is detected in the pharynx and hindgut. sgl is detected ubiquitously in most third instar larval imaginal discs. Low levels of sgl are detected in the eye imaginal disc, with the highest concentration found in the morphogenetic furrow.
GBrowse - Visual display of RNA-Seq signals
View Dmel\sgl in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: sgl CG10072
Source for merge of: sgl BG01214
"kiwi" has been used as a valid symbol for FBgn0020295 and as a synonym for sgl, FBgn0010851.
Loss of both maternal and zygotic sgl function results in profound defects in mesoderm and tracheal cell migration in the embryo.
Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.
sgl mutants lack UDP-glucose dehydrogenase activity.
sgl mutants lack glycosaminoglycan chains on proteoglycans.
The autosomal "FLP-DFS" technique (using the P{ovoD1-18} P{FRT(whs)} P{hsFLP} chromosomes) has been used to identify the specific maternal effect phenotype for the zygotic lethal mutation.