kiwi, suppenkasper, ska, UDPGDH, BG01214
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\sgl using the Feature Mapper tool.
sgl transcript is distributed uniformly in the embryo before stage 4. By stage 9, sgl expression has become restricted to the areas surrounding the cephalic furrow, and the presumptive amnioserosa. Expression in the amnioserosa persists at least until stage 14 of embryogenesis.
sgl is expressed both maternally and ubiquitously throughout embryonic development.
sgl transcript is found in the early embryo. After germ band extension, signal is more intense in the mesoderm. After germ band retraction, sgl is expressed in the midgut. After dorsal closure, sgl expression is detected in the pharynx and hindgut. sgl is detected ubiquitously in most third instar larval imaginal discs. Low levels of sgl are detected in the eye imaginal disc, with the highest concentration found in the morphogenetic furrow.
GBrowse - Visual display of RNA-Seq signalsView Dmel\sgl in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Loss of both maternal and zygotic sgl function results in profound defects in mesoderm and tracheal cell migration in the embryo.
Identification: Enhancer trap expression pattern survey for loci expressed in the ring gland.