CAP, acu, l(2)06955, act up, cyclase-associated protein
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\capt using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\capt in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: BcDNA:LD24380 CG5061
Annotations CG5061 and CG5074 merged as CG33979 in release 4.3 of the genome annotation.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
dsRNA made from templates generated with primers directed against this gene is tested in an RNAi screen for effects on actin-based lamella formation.
Mutant show altered F-actin and oocyte polarity during oogenesis.
capt is required to prevent excessive polymerisation of actin filaments in the eye disc. It is also required for cells to change shape in the morphogenetic furrow and prevents premature neuronal differentiation in the eye disc.
capt is required for cells to constrict apically in the morphogenetic furrow in the eye disc and is also required to prevent premature neuronal differentiation.
Identification: identified as a mutation that affects both the actin cytoskeleton and oocyte polarity in female germline clones.
Loss of capt function in clones results in the dramatic re-organisation of actin filaments in many tissues, leading to the loss of some actin structures and the accumulation of massive clumps of F-actin at characteristic ectopic sites.