snRNP-U1, snRNPC, U1C
Gene model reviewed during 5.43
Gene model reviewed during 5.53
There is only one protein coding transcript and one polypeptide associated with this gene
U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\snRNP-U1-C using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\snRNP-U1-C in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: snRNP-U1 CG5454
Source for merge of CG5454 BcDNA:RH29440 was a shared cDNA ( date:030728 ).
RNAi screen using dsRNA made from templates generated with primers directed against this gene results in a long metaphase spindle with misaligned chromosomes when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Identified as a protein specific to U1 small nuclear ribonucleoprotein particles (snRNPs).