FlyBase Gene Report: Dmel\whd

PALMITOYLTRANSFERASES -: Palmitoyltransferases catalyze the post-translational addition of a palmitate moiety to a cysteine residue through a covalent thioester bond. (Adapted from FBrf0210485).

Phenotypic Description (Red Book; Lindsley and Zimm 1992)

whd: withered

Wings warped and waved or reduced to shrunken black pupal pads. Synthetic lethal in presence of su(r) (Strømen, 1974). RK2.

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\whd or the JBrowse view of Dmel\whd for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

whd-RA

FBtr0088307

NM_078961

2882

780

whd-RB

FBtr0088308

NM_165777

2901

780

whd-RC

FBtr0301281

NM_001169640

2888

782

whd-RD

FBtr0301282

NM_001169641

2907

782

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

whd-PA

FBpp0087399

89.4

780

8.56

NP_523685

AAF58785

whd-PB

FBpp0087400

89.4

780

8.56

NP_724940

AAF58786

whd-PC

FBpp0290496

89.5

782

8.48

NP_001163111

ACZ94386

whd-PD

FBpp0290497

89.5

782

8.48

NP_001163112

ACZ94387

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

780 aa isoforms: whd-PA, whd-PB

782 aa isoforms: whd-PC, whd-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\whd using the Feature Mapper tool.

External Data

Crossreferences

Linkouts

Gene Ontology (8 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

carnitine O-palmitoyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN001097100

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (5 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

response to metal ion

inferred from mutant phenotype

(Strub et al., 2008)

response to oxidative stress

inferred from mutant phenotype

(Strub et al., 2008)

response to starvation

inferred from mutant phenotype

(Strub et al., 2008)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

carnitine metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN001097100

(assigned by GO_Central )

(Gaudet et al., 2011)

fatty acid metabolic process

inferred from biological aspect of ancestor with PANTHER:PTN001097100

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

mitochondrion

inferred from biological aspect of ancestor with PANTHER:PTN001097100

(assigned by GO_Central )

(Gaudet et al., 2011)

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

posterior ectoderm anlage

Comment: anlage in statu nascendi

(Fisher et al., 2012)

embryonic stage 7 -- 8

anterior endoderm anlage

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

embryonic stage 9 -- 10

anterior endoderm

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

dorsal epidermis primordium

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

ventral epidermis primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic dorsal epidermis

(Fisher et al., 2012)

embryonic ventral epidermis

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

RT-PCR

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

embryonic/larval brain

(Price et al., 2010)

embryonic/larval fat body

(Price et al., 2010)

embryonic/larval gut

(Price et al., 2010)

adult stage

adult muscle system

(Price et al., 2010)

flight muscle

(Price et al., 2010)

adult fat body

(Price et al., 2010)

Additional Descriptive Data

Two different isoforms of whd protein are produced through the use of alternative exons 6A and 6B. Transcripts for both isoforms are detected in all larval and adult tissues tested by RT-PCR. Transcripts containing alternative exon 6B are present at similar levels in the tissues tested. By contrast, transcripts containing alternative exon 6A are significantly more prevalent in flight muscle than fat body.

(Price et al., 2010)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

endomembrane system

inferred from high throughput direct assay

(Tan et al., 2009)

Expression Deduced from Reporters

Reporter: P{ST.lexA::HG}whd^IP-1

Stage

Tissue/Position (including subcellular localization)

Reference

wandering third instar larval stage

eye disc

(Bloomington Drosophila Stock Center, 2019)

embryonic/larval central nervous system

(Bloomington Drosophila Stock Center, 2019)

ventral nerve cord

(Bloomington Drosophila Stock Center, 2019)

embryonic/larval salivary gland

(Bloomington Drosophila Stock Center, 2019)

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\whd in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\whd

View exonic expression by tissue for Dmel\whd

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0261862

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG12891

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, and Transgenic Constructs

Classical and Insertion Alleles ( 37 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 6 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of whd

Transgenic constructs containing regulatory region of whd

Deletions and Duplications ( 7 )

Not disrupted in

Df(2R)E3363

(Strub et al., 2008)

Df(2R)en-A

(Chase and Baker, 1995)

Df(2R)en-B

(Chase and Baker, 1995)

Df(2R)X1

(Strub et al., 2008)

Disrupted in

Df(2R)12

(Strub et al., 2008)

Df(2R)stan1

(Strub et al., 2008)

Df(2R)stan2

(Strub et al., 2008)

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal | chemical conditional

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

whd^GD1917

viable, with Scer\GAL4^Mef2.PR

whd^GD1917

viable, with Scer\GAL4^pnr-MD237

whd^GD1917

viable, with Scer\GAL4^tin.CΔ4

whd^GD1917

Other Phenotypes

Allele

chemical sensitive

developmental rate defective | chemical conditional

immune response defective | adult stage

whd¹

radiation sensitive

whd¹

stress response defective

visible (with whd¹)

visible (with whd²)

whd¹

visible (with whd³)

whd¹

visible (with whd⁴)

whd¹

visible (with whd⁵)

whd¹

visible (with whd⁶)

whd¹

visible (with whd⁷)

whd¹

visible (with whd⁸)

whd¹

visible (with whd⁹)

whd¹

visible (with whd¹⁰)

whd¹

visible (with whd¹¹)

whd¹

visible (with whd¹²)

whd¹

visible (with whd¹³)

whd¹

visible (with whd¹⁴)

whd¹

visible | recessive

Phenotype manifest in

Allele

adult brain

whd^EY20655

flight muscle

whd^EY20655

lipid droplet

whd^EY20655

wing

wing (with whd¹)

wing (with whd²)

whd¹

wing (with whd³)

whd¹

wing (with whd⁴)

whd¹

wing (with whd⁵)

whd¹

wing (with whd⁶)

whd¹

wing (with whd⁷)

whd¹

wing (with whd⁸)

whd¹

wing (with whd⁹)

whd¹

wing (with whd¹⁰)

whd¹

wing (with whd¹¹)

whd¹

wing (with whd¹²)

whd¹

wing (with whd¹³)

whd¹

wing (with whd¹⁴)

whd¹

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (8)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\CPT1A

13 of 15

Yes

Hsap\CPT1B

12 of 15

Yes

Hsap\CPT1C

10 of 15

Yes

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (6)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Cpt1a

13 of 15

Yes

Mmus\Cpt1b

13 of 15

Yes

Mmus\Cpt1c

10 of 15

Yes

Mmus\Chat

2 of 15

Mmus\Crat

2 of 15

Mmus\Cpt2

1 of 15

Rattus norvegicus (Norway rat) (6)

Rnor\Cpt1a

12 of 13

Yes

Rnor\Cpt1b

12 of 13

Yes

Rnor\Cpt1c

9 of 13

Yes

Rnor\Chat

2 of 13

Rnor\Crat

2 of 13

Rnor\Crot

1 of 13

Xenopus tropicalis (Western clawed frog) (6)

Xtro\cpt1b

11 of 12

Yes

Xtro\cpt1a

8 of 12

Yes

Xtro\chat

1 of 12

Xtro\cpt1a

1 of 12

Yes

Xtro\crat.1

1 of 12

Xtro\crat.2

1 of 12

Danio rerio (Zebrafish) (13)

Drer\cpt1b

12 of 15

Yes

Drer\cpt1aa

11 of 15

Yes

Drer\cpt1ab

11 of 15

Yes

Drer\cpt1cb

9 of 15

Yes

Drer\LOC100333227

6 of 15

Yes

2 of 15

2 of 15

2 of 15

2 of 15

1 of 15

1 of 15

1 of 15

Drer\si:ch211-256m1.8

1 of 15

Caenorhabditis elegans (Nematode, roundworm) (13)

Cele\cpt-1

12 of 15

Yes

Cele\W03F9.4

4 of 15

Yes

Cele\cpt-3

3 of 15

Yes

Cele\cpt-4

3 of 15

Yes

Cele\cpt-6

3 of 15

Yes

2 of 15

1 of 15

1 of 15

1 of 15

Yes

Cele\F41E7.6

1 of 15

Cele\R08A2.5

1 of 15

Yes

Cele\T20B3.1

1 of 15

Cele\W08A12.2

1 of 15

Yes

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (3)

Scer\CAT2

5 of 15

Yes

Scer\YAT1

2 of 15

Scer\YAT2

2 of 15

Yes

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091902HE )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\whd

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA11884

Drosophila persimilis

Dper\GL17200

Drosophila willistoni

Dwil\GK10678

Drosophila virilis

Dvir\GJ20140

Drosophila mojavensis

Dmoj\GI20192

Drosophila grimshawi

Dgri\GH20631

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091501DJ )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17016243

Glossina morsitans

Tsetse fly

Gmor\GMOY005222

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_13326

Mayetiola destructor

Hessian fly

Mdes\Mdes003169

Mayetiola destructor

Hessian fly

Mdes\Mdes008886

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005458

Anopheles darlingi

American malaria mosquito

Adar\ADAC007910

Anopheles gambiae

Malaria mosquito

Agam\AGAP010164

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ005612

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W01UH )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA013317

Danaus plexippus

Monarch butterfly

Dple\DPOGS203036-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL014078

Apis florea

Little honeybee

Aflo\2556514532

Apis mellifera

Western honey bee

Amel\GB54622

Bombus impatiens

Common eastern bumble bee

Bimp\BIMP24283

Bombus terrestris

Buff-tailed bumblebee

Bter\15208433

Linepithema humile

Argentine ant

Lhum\LH10209

Megachile rotundata

Alfalfa leafcutting bee

Mrot\MROTU:002679

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG007262

Dendroctonus ponderosae

Mountain pine beetle

Dpod\YQE_02649

Tribolium castaneum

Red flour beetle

Tcas\TC002462

Pediculus humanus

Human body louse

Phum\PHUM022280

Rhodnius prolixus

Kissing bug

Rpro\RPRC005639

Cimex lectularius

Bed bug

Clec\CLEC000184

Cimex lectularius

Bed bug

Clec\CLEC000183

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI005329

Zootermopsis nevadensis

Nevada dampwood termite

Znev\Znev_06178

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X0207 )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strigamia maritima

European centipede

Smar\SMAR011529

Ixodes scapularis

Black-legged tick

Isca\ISCW018288

Stegodyphus mimosarum

African social velvet spider

Smim\KFM81044.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM58548.1

Stegodyphus mimosarum

African social velvet spider

Smim\KFM58547.1

Tetranychus urticae

Two-spotted spider mite

Turt\tetur05g06670

Daphnia pulex

Water flea

Dpux\DAPPUDRAFT_57941

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G026C )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Cpt1a

Strongylocentrotus purpuratus

Purple sea urchin

Spur\Sp-Cpt1a_1

Ciona intestinalis

Vase tunicate

Cint\ENSCING00000003450

Gallus gallus

Domestic chicken

Ggal\CPT1A

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v7.1)

Drosophila melanogaster (Fruit fly) (6)

Gene Symbol

Score

Source

Alignment

4 of 10

4 of 10

4 of 10

3 of 10

2 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 2 )

Human Ortholog

Disease

Evidence

References

CPT1A; carnitine palmitoyltransferase 1A

model of carnitine palmitoyltransferase I deficiency

IEA

(FlyBase, 2019-)

CPT1C; carnitine palmitoyltransferase 1C

model of hereditary spastic paraplegia 73

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v7.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CPT1A; carnitine palmitoyltransferase 1A

13 of 15

600528

CARNITINE PALMITOYLTRANSFERASE I DEFICIENCY

carnitine palmitoyltransferase I deficiency

CPT1B; carnitine palmitoyltransferase 1B

12 of 15

601987

CPT1C; carnitine palmitoyltransferase 1C

10 of 15

608846

SPASTIC PARAPLEGIA 73, AUTOSOMAL DOMINANT; SPG73

hereditary spastic paraplegia 73

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

whd - CG32219

experimental knowledge based

(Guruharsha et al., 2011)

whd - CG3565

experimental knowledge based

(Guruharsha et al., 2011)

whd - sima

anti tag coimmunoprecipitation, Identification by mass spectrometry

(Vinayagam et al., 2016)

Summary of Genetic Interactions

esyN Network Diagram

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0261862

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

36109

MIST (protein-protein) - An integrated Molecular Interaction Database

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-62

Cytogenetic map

47A9-47A11

Sequence location

2R:10,469,473..10,478,567 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

47A9-47A11

Limits computationally determined from genome sequence between P{lacW}Hr46^k10308 and P{PZ}lola⁰⁰³⁴⁹&P{EP}lola^EP952

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-62

(FlyBase, 2016)

2-61.1

(Comeron et al., 2012)

2-61

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (25)

Bloomington

441

whd¹

66624

w^*; P{ST.lexA::HG}whd^IP-1

33635

y¹ v¹; P{TRiP.HMS00033}attP2

Kyoto

113330

w^*; P{GawB}whd^NP3533

123205

w¹¹¹⁸; P{RS3}whd^CB-0496-3

124202

w¹¹¹⁸; P{RS3}whd^CB-6742-3

125189

w¹¹¹⁸; P{RS5}whd^5-HA-1287

125798

w¹¹¹⁸; P{RS5}whd^5-HA-3096

112982

w^*; P{GawB}whd^NP2610-3-1 / CyO

VDRC

v105400

P{KK100935}VIE-260B

v4046

w¹¹¹⁸; P{GD1917}v4046

v4047

w¹¹¹⁸; P{GD1917}v4047

More stocks available...

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (142)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

Other clones

MIP15836

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0261862

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0261862

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

36109

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for database merge of

Source for merge of: CPTI BEST:GH27794

(FlyBase, 1996-)

Source for merge of: whd CPTI

(Strub et al., 2008)

Additional comments

Other Comments

Nonsense-mediated mRNA decay (NMD) down-regulates a distinct splice isoform(s) of this gene.

(Hansen et al., 2009)

Transcriptionally downregulated after 2h of insulin stimulation in Kc167 cells. Contains fkh response elements (FHREs) in the genomic upstream or intronic sequences.

(Junger et al., 2003)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 51 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

36109

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0261862

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0261862

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG12891

FlyMine - An integrated database for Drosophila genomics

FBgn0261862

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

36109

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC002462

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG12891

modMine - A data warehouse for the modENCODE project

FBgn0261862

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0261862

DRSC - Results frm RNAi screens

FBgn0261862

InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.

36109

KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.

MIST (protein-protein) - An integrated Molecular Interaction Database

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Synonyms and Secondary IDs (15)

Reported As

Symbol Synonym

BEST:GH27794

CG12891

(Buescher et al., 2013, Chambers et al., 2012, Jaspers et al., 2012, Cammarato et al., 2011, Musselman et al., 2011, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Hansen et al., 2009, Keleman et al., 2009.8.5, Strub et al., 2008, Teleman et al., 2008, Philipps et al., 2004)

CPT1

(Xu et al., 2019, Manzo et al., 2018, van der Hoek et al., 2018, Buescher et al., 2013, Price et al., 2010)

CPTI

(Kanda et al., 2011, Wang et al., 2011, Kong et al., 2010, Maynard et al., 2010, Hansen et al., 2009, Palanker et al., 2009, Tan et al., 2009, Liu and Lehmann, 2008, Strub et al., 2008, Teleman et al., 2008, Claussen et al., 2006, Philipps et al., 2004)

Cpt1

(Buescher et al., 2013)

cpt1

(Wang et al., 2016)

dCPT1

(Schulz et al., 2015)

gh27794

(Zou et al., 2000)

whd

(Chen et al., 2019, Kong et al., 2019, Gene Disruption Project members, 2018-, Levis, 2018.8.30, Manzo et al., 2018, Transgenic RNAi Project members, 2017-, Kockel et al., 2016, Logan-Garbisch et al., 2014, Friedman et al., 2011, Strub et al., 2008)

Name Synonyms

carnitin-palmitoyl transferase-I

(Kanda et al., 2011)

carnitine palmitoyltransferase 1

(Price et al., 2010)

carnitine-O-palmitoyltransferase

(Gronke et al., 2005)

mitochondrial carnitine palamitoyltransferase I

(Maynard et al., 2010)

mitochondrial carnitine palmitoyltransferase I

(Jaspers et al., 2012, Cammarato et al., 2011)

withered

(Logan-Garbisch et al., 2014, Von Ohlen et al., 2012, Strub et al., 2008)

Secondary FlyBase IDs

FBgn0004012
FBgn0027842
FBgn0043803

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (81)

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