A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\l(2)35Be

General Information
SymbolDmel\l(2)35BeSpeciesD. melanogaster
Namelethal (2) 35BeAnnotation symbolCG4140
Feature typeprotein_coding_geneFlyBase IDFBgn0261881
Gene Model StatusCurrent Stock availability 4 publicly available
Also Known Asl(2)br10, BG:DS00929.2, br10
Genomic Location
Chromosome (arm)2LRecombination map2-[50]
Cytogenetic map35B8-35B8Sequence location2L:15,006,583..15,007,404 [-]

Genomic Maps

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modENCODE GBrowse
detailed view
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Automatically generated summary

See sections below for more information
The gene lethal (2) 35Be is referred to in FlyBase by the symbol Dmel\l(2)35Be (CG4140, FBgn0261881). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 10 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain. Gene sequence location is 2L:15006583..15007404.

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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
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atom feed
FB2011_10
FB2012_01
Sequence features
BKN28693
HFA01894
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
35B8-35B8  
Limits computationally determined from genome sequence between P{EP}elBEP2039&P{PZ}osprJ571 and P{lacW}Su(H)k07904  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
2-[50]
 
Left of (cM)
(Woodruff and Ashburner, 1979)
Right of (cM)
(Woodruff and Ashburner, 1979)
Notes
Complementation analysis establishes the following gene order (distal to proximal): dyn-p25, l(2)35Be, l(2)35Bc.
(Ashburner et al., 1999)
Excision of l(2)35Bck08808 indicates that the gene order is mol, dyn-p25, l(2)35Be, l(2)35Bc, l(2)35Bd.
(Ashburner et al., 1999.10.12)
hide Gene Model & Products
Please see the GBrowse view of Dmel\l(2)35Be for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0080693 FBtr0080728 FBtr0080695 FBtr0080727 FBtr0303561 FBpp0080255 FBpp0080287 FBpp0080256 FBpp0292594 FBpp0080286 FBti0050796 FBti0041011 FBti0068208
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
l(2)35Be-RA
FBtr0080728
 NM_135891
  773
  215
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
l(2)35Be-PA  
FBpp0080287  
24.2  
215  
4.45  
  NP_609735
  AAF53427
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Ankyrin repeat (IPR002110)
Ankyrin repeat-containing domain (IPR020683)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AA539145
 
AE014134
AAF53427
 
AE003411
AAF44906
 
AY070830
AAL48452
 
BG633874
 
BI637081
 
EC067655
 
EV597679
 
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view dyn-p25-RA l(2)35Be-RA NC2beta-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
(The modENCODE Consortium, 2010)
hide External Data & Images
Linkouts
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
lethal | recessive
viable, with Scer\GAL4pnr-MD237
Other Phenotypes
Allele
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
mesothoracic tergum, with Scer\GAL4pnr-MD237
hide Classical Alleles ( 8 )
For All Classical Alleles Show

Allele of l(2)35BeClassMutagenStocksKnown lesion
l(2)35Be12 --
l(2)35Be41 Yes
l(2)35Be20 Yes
l(2)35Be30 --
l(2)35Be50 --
l(2)35Be60 --
l(2)35Be70 --
l(2)35BeCPTI000130
0 --
hide Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show

Allele of l(2)35BeClassMutagenStocksKnown lesion
l(2)35BeGD112271 Yes
l(2)35BeKK1086930 Yes
hide Aneuploid Aberrations
Not disrupted in
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Roote, 1996.8)
(Woodruff and Ashburner, 1979)
(Furukawa et al., 1992)
(Woodruff and Ashburner, 1979)
(Woodruff and Ashburner, 1979, Ashburner et al., 1982, O'Donnell et al., 1977)
(Ashburner, 1982, Ashburner et al., 1982, O'Donnell et al., 1977, Woodruff and Ashburner, 1979)
(O'Donnell et al., 1977, Ashburner et al., 1982, Woodruff and Ashburner, 1979, Ashburner, 1982)
(Ashburner et al., 1982, O'Donnell et al., 1977)
(Roote, 2000.6.13)
(Roote, 2000.6.13)
(Roote, 2000.6.13)
(Roote, 2000.6.13)
(Furukawa et al., 1992)
(Ashburner, 1982)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1984, Ashburner, 1982)
(Ashburner, 1982, Gubb et al., 1984)
(Iyengar et al., 1999, Gubb et al., 1984)
(Furukawa et al., 1992)
(Furukawa et al., 1992)
(Furukawa et al., 1992)
(Furukawa et al., 1992)
(Furukawa et al., 1992)
(Woodruff and Ashburner, 1979)
(Woodruff and Ashburner, 1979)
(Woodruff and Ashburner, 1979)
(Woodruff and Ashburner, 1979)
(Woodruff and Ashburner, 1979)
Disrupted in
(Woodruff and Ashburner, 1979, Ashburner, 1982, Furukawa et al., 1992, O'Donnell et al., 1977)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982, Furukawa et al., 1992)
(Ashburner et al., 1982)
(Ashburner et al., 1982)
(Ashburner et al., 1982, Ashburner, 1982)
(Ashburner, 1982, Ashburner et al., 1982)
(Ashburner et al., 1982, Ashburner, 1982)
(Furukawa et al., 1992, Ashburner, 1982)
(Furukawa et al., 1992)
(Furukawa et al., 1992)
(Ashburner, 1982)
(Furukawa et al., 1992)
(Ryder, 2004.4.26)
(Ashburner et al., 1982, Woodruff and Ashburner, 1979, O'Donnell et al., 1977)
(Furukawa et al., 1992, Ashburner et al., 1982, O'Donnell et al., 1977)
(Ashburner et al., 1982, Woodruff and Ashburner, 1979)
(Ashburner et al., 1982, O'Donnell et al., 1977)
(Ashburner et al., 1982)
(O'Donnell et al., 1977, Ashburner et al., 1982, Ashburner, 1982)
(Ashburner et al., 1982, O'Donnell et al., 1977)
(Ashburner et al., 1982, O'Donnell et al., 1977, Ashburner, 1982)
(Roote, 2000.6.13)
(Furukawa et al., 1992)
(Woodruff and Ashburner, 1979)
(Ashburner, 1982)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Gubb et al., 1985)
(Ashburner, 1982, Gubb et al., 1984)
(Gubb et al., 1984)
(Gubb et al., 1984, Furukawa et al., 1992)
(Gubb et al., 1984)
(Gubb et al., 1984)
(Furukawa et al., 1992, Gubb et al., 1984)
(Gubb et al., 1984)
(Gubb et al., 1984)
(Gubb et al., 1984)
(Gubb et al., 1984)
(Woodruff and Ashburner, 1979, Ashburner, 1982)
(Ashburner and Harrington, 1984)
(Ashburner and Harrington, 1984)
(Gubb et al., 1985)
(Ashburner and Harrington, 1984)
(Ashburner and Harrington, 1984)
(Woodruff and Ashburner, 1979)
(Ashburner et al., 1982)
(Ashburner and Harrington, 1984)
(Ashburner and Harrington, 1984)
Duplicated in
(Ashburner, 1982)
(Ashburner, 1982)
(Ashburner, 1982)
(Ashburner, 1982)
(Ashburner, 1982)
Not duplicated in
(Ashburner, 1982)
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
UAS construct
P{KK108693}
NA
Insertions
Type of insertions
Name
Expression data
miscellaneous insertions
PBac{602.P.SVS-1}l(2)35BeCPTI000130
NA
hide Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
hide Terms Based on Experimental Evidence ( 0 terms )
hide Terms Based on Predictions or Assertions ( 0 terms )
hide Sequence Ontology: Class of Gene
gene
 
nuclear_gene
 
protein_coding_gene
 
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
l(2)35Be allele
Gene
References
hide External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
•
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
•
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
 
Linkouts
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
•
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 4 )
Bloomington
3181
AdhUF l(2)35Be4 rds pr1 cn1/CyO
2239
b1 l(2)35Be1 pr1/In(2L)Cy, In(2R)Cy, al2 Cy1 pr1 Bl1 cn2 vg1 c1 sp2
Kyoto
101315
b1 l(2)35Be1 pr1 / In(2L)Cy In(2R)Cy, al2 Cy1 pr1 Bl1 cn2 vg1 c1 sp2
VDRC
v26396
w1118; P{GD11227}v26396
hide Genomic Clones ( 1 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 6 )

Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
•
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
hide Antibody Information
hide Other Information
hide Discoverer
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for identity of: BG:DS00929.2 CG4140
(Kodira, 1999.11)
Source for database merge of
Source for merge of: l(2)35Be CG4140
(Huen and Roote, 2010.5.4)
Additional comments
"BG:DS00929.1", "BG:DS00929.2" or "BG:DS00929.3" may correspond to "l(2)35Be".
(Ashburner et al., 1999.10.12)
"BG:DS00929.2" may correspond to "l(2)35Bf", "l(2)35Be" or "l(2)35Bc".
(Ashburner et al., 1999.10.12)
hide Other Comments
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
•
RefSeq (Proteins)
•
DDBJ / EMBL / GenBank
•
Entrez Gene - A searchable database of RefSeq genes.
•
UniProtKB/TrEMBL
•
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Ankyrin repeat (IPR002110)
Ankyrin repeat-containing domain (IPR020683)
Linkouts
DroID - A comprehensive database of gene and protein interactions.
•
DRSC - Results from RNAi screens.
•
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
•
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
•
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
•
modMine - Data generated by the modENCODE project.
•
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
•
hide Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym
BG:DS00929.2
(Ashburner et al., 1999.10.12, Ashburner et al., 1999, Ashburner et al., 1999, Giot et al., 2003, )
br10
(Furukawa et al., 1992, Gubb et al., 1985, Ashburner and Harrington, 1984)
C3
(O'Donnell et al., 1977)
CG4140
(Huen and Roote, 2010.5.4, Keleman et al., 2009.8.5)
l(2)35Be
(Huen and Roote, 2010.5.4, )
l(2)br10
(The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Gubb et al., 1984, Ashburner, 1982, Ashburner et al., 1982, Woodruff and Ashburner, 1979, )
Name Synonym
lethal 10 in the black-reduced region
(Woodruff and Ashburner, 1979)
lethal (2) 35Be
 
lethal group C3
(O'Donnell et al., 1977)
Secondary FlyBase IDs
  • FBgn0001975
  • FBgn0027870
  • FBgn0028535
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