FB2020_06, released Dec 22, 2020

Gene: Dmel\osa

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General Information
Symbol
Dmel\osa
Species
D. melanogaster
Name
osa
Annotation Symbol
CG7467
Feature Type
protein_coding_gene
FlyBase ID
FBgn0261885
Gene Model Status
Current
Stock Availability
23 publicly available
Gene Snapshot
osa (osa) encodes a subunit of the BAP chromatin remodeling complex. It antagonizes Wnt target gene expression and limits the self-renewal of neural and intestinal stem cells. [Date last reviewed: 2019-03-14]
Other Summaries
Also Known As

eld, eyelid, l(3)00090, C819

Key Links
Genomic Location
Cytogenetic map
90C1-90C2
Sequence location
3R:17,687,818..17,718,350 [-]
Recombination map

3-61

RefSeq locus
NT_033777 REGION:17687818..17718350
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (22 terms)
Molecular Function (2 terms)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables DNA binding
inferred from direct assay
(assigned by UniProt )
(Collins et al., 1999)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
enables DNA binding
non-traceable author statement
(assigned by UniProt )
(Treisman et al., 1997)
contributes_to nucleosome binding
inferred from biological aspect of ancestor with PANTHER:PTN000291886
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (14 terms)
Terms Based on Experimental Evidence (13 terms)
CV Term
Evidence
References
involved_in imaginal disc-derived leg morphogenesis
inferred from mutant phenotype
(Terriente-Félix and de Celis, 2009)
involved_in imaginal disc-derived wing margin morphogenesis
inferred from mutant phenotype
(Terriente-Félix and de Celis, 2009)
inferred from mutant phenotype
(assigned by UniProt )
(Treisman et al., 1997)
involved_in imaginal disc-derived wing morphogenesis
inferred from mutant phenotype
(Dworkin and Gibson, 2006)
involved_in imaginal disc-derived wing vein morphogenesis
inferred from mutant phenotype
(Terriente-Félix and de Celis, 2009)
involved_in negative regulation of neuroblast proliferation
inferred from genetic interaction with FLYBASE:numb; FB:FBgn0002973
(Janssens et al., 2014)
inferred from genetic interaction with FLYBASE:brat; FB:FBgn0010300
(Janssens et al., 2014)
involved_in neuroblast fate commitment
inferred from mutant phenotype
(Eroglu et al., 2014)
involved_in photoreceptor cell differentiation
inferred from mutant phenotype
(assigned by UniProt )
(Treisman et al., 1997)
involved_in positive regulation of transcription, DNA-templated
inferred from physical interaction with FLYBASE:ham; FB:FBgn0045852
(Eroglu et al., 2014)
inferred from direct assay
(Kal et al., 2000)
involved_in regulation of transcription by RNA polymerase II
inferred from mutant phenotype
(Bonnay et al., 2014)
involved_in regulation of transcription, DNA-templated
inferred from direct assay
(assigned by UniProt )
(Collins et al., 1999)
inferred from mutant phenotype
(assigned by UniProt )
(Vazquez et al., 1999)
involved_in segment specification
inferred from mutant phenotype
(assigned by UniProt )
(Treisman et al., 1997)
involved_in wing disc dorsal/ventral pattern formation
inferred from genetic interaction with FLYBASE:Bx; FB:FBgn0265598, FLYBASE:ap; FB:FBgn0267978
(Bejarano et al., 2008)
involved_in Wnt signaling pathway
inferred from mutant phenotype
(assigned by UniProt )
(Treisman et al., 1997)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
involved_in ATP-dependent chromatin remodeling
inferred from biological aspect of ancestor with PANTHER:PTN000291886
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in positive regulation of transcription, DNA-templated
inferred from biological aspect of ancestor with PANTHER:PTN000291886
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in regulation of transcription by RNA polymerase II
inferred from biological aspect of ancestor with PANTHER:PTN000291886
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (6 terms)
Terms Based on Experimental Evidence (4 terms)
CV Term
Evidence
References
part_of brahma complex
inferred from direct assay
(Mohrmann et al., 2004, Kal et al., 2000)
located_in nucleoplasm
inferred from high throughput direct assay
(Lye et al., 2014)
located_in nucleus
inferred from direct assay
(assigned by UniProt )
(Treisman et al., 1997)
located_in polytene chromosome
inferred from direct assay
(Collins et al., 1999)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
part_of nBAF complex
inferred from biological aspect of ancestor with PANTHER:PTN002652024
(assigned by GO_Central )
(Gaudet et al., 2011)
located_in nucleoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000291886
(assigned by GO_Central )
(Gaudet et al., 2011)
part_of SWI/SNF complex
inferred from biological aspect of ancestor with PANTHER:PTN000291886
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
BRAHMA ASSOCIATED PROTEINS COMPLEX -
Brahma (BRM) complexes are ATP-dependent chromatin remodeling complexes that regulate nucleosome organization. Two BRM complexes have been identified in D.mel, BAP and PBAP. (Adapted from FBrf0192510).
A-T RICH INTERACTION DOMAIN TRANSCRIPTION REGULATORS -
The A-T Rich Interaction Domain (ARID) transcription regulators are non-sequence specific DNA binding proteins. The ARID domain comprises a variant helix-turn-helix motif, accompanied by additional DNA-contacting loop structures. Many have roles in chromatin remodelling and regulation of general transcription. (Adapted from PMID:15922553).
Protein Function (UniProtKB)
Trithorax group (trxG) protein required for embryonic segmentation, development of the notum and wing margin, and photoreceptor differentiation. Required for the activation of genes such as Antp, Ubx and Eve. Binds to DNA without specific affinity, suggesting that it is recruited to promoters by promoter-specific proteins. Essential component of the Brahma complex, a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Acts as an essential coactivator for Zeste, which recruits the whole complex to specific genes. In contrast, it acts as a corepressor for Wg target genes, possibly via an interaction with Pan and Gro. It also acts as a negative regulator for proneural achaete-scute, when it is directly recruited by Pan and Chi. Also represses E2f activation.
(UniProt, Q8IN94)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
osa: osa (J.A. Kennison)
Isolated as a dominant suppressor of the antenna to leg transformation in Pc2 AntpNs double heterozygotes. Also acts as a dominant suppressor of AntpNs, Pc and Pcl alleles. Recessive embryonic lethality associated with all alleles. Also fails to complement In(3R)Antprv1 for viability.
Summary (Interactive Fly)

transcription factor - Bright family - associates with the Brahma chromatin remodeling complex - antagonizes Wingless signaling during Drosophila development and affects patterning of the eye imaginal disc

Gene Model and Products
Number of Transcripts
6
Number of Unique Polypeptides
5

Please see the JBrowse view of Dmel\osa for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene
gene
(Molnar et al., 2006)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
osa-RA
FBtr0089582
NM_169775
10675
2703
osa-RB
FBtr0089581
NM_079668
10714
2716
osa-RC
FBtr0089583
NM_206506
10234
2556
osa-RD
FBtr0301487
NM_001170168
10423
2716
osa-RE
FBtr0335024
NM_001275751
9940
2555
osa-RF
FBtr0335025
NM_001275752
10243
2559
Additional Transcript Data and Comments
Reported size (kB)

10.601 (sequence analysis)

(Treisman et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
osa-PA
FBpp0088544
282.9
2703
7.49
NP_732263
AAF55457
osa-PB
FBpp0088543
284.1
2716
7.45
NP_524392
AAN13750
osa-PC
FBpp0088962
269.0
2556
7.46
NP_996228
AAS65166
osa-PD
FBpp0290702
284.1
2716
7.45
NP_001163639
ACZ94935
osa-PE
FBpp0307030
268.8
2555
7.46
NP_001262680
AGB96060
osa-PF
FBpp0307031
269.3
2559
7.50
NP_001262681
AGB96061
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

2716 aa isoforms: osa-PB, osa-PD
Additional Polypeptide Data and Comments
Reported size (kDa)

2715 (aa)

(Treisman et al., 1997)
Comments
External Data
Subunit Structure (UniProtKB)

Component of the Brahma complex, which is composed of Brm, Osa, Mor, Snr1/Bap45, Bap111/Dalao, Bap55, Bap60 and Bap47. Interacts with Pnr and Chi via its EHD domain.

(UniProt, Q8IN94)
Domain

The ARID domains mediates the binding to DNA.

(UniProt, Q8IN94)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\osa using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
larval stage
wing disc
(Treisman et al., 1997)
embryonic/larval salivary gland
(Collins et al., 1999)
morphogenetic furrow | anterior to
(Treisman et al., 1997)
eye disc
(Treisman et al., 1997)
embryonic stage 5
organism | ubiquitous
(Treisman et al., 1997)
third instar larval stage
embryonic/larval fat body
(Banreti et al., 2014)
Additional Descriptive Data

Protein was localized along the entire length of all chromosomes. In vitro binding assays showed that osa protein bound DNA without sequence specificity.

(Collins et al., 1999, Treisman et al., 1997)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
part_of brahma complex
inferred from direct assay
(Mohrmann et al., 2004, Kal et al., 2000)
located_in nucleoplasm
inferred from high throughput direct assay
(Lye et al., 2014)
located_in nucleus
inferred from direct assay
(assigned by UniProt )
(Treisman et al., 1997)
located_in polytene chromosome
inferred from direct assay
(Collins et al., 1999)
Expression Deduced from Reporters
Reporter: PBac{754.P.FSVS-0}osaCPTI003089
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult brain cell body rind
(Knowles-Barley, 2011.8.24)
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\osa in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 65 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of osa
Transgenic constructs containing regulatory region of osa
Deletions and Duplications ( 5 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal
lethal, with Scer\GAL4Act5C.PU
lethal, with Scer\GAL4bi-omb-Gal4
lethal, with Scer\GAL4Bx-MS1096
lethal, with Scer\GAL4c564
lethal, with Scer\GAL4GMR.PF, Scer\GAL4ey.PH
lethal, with Scer\GAL4pnr-MD237
lethal (with Df(3R)BSC790)
lethal (with osa1)
lethal (with osa2)
lethal (with osaArv1)
lethal | embryonic stage | germline clone | non-rescuable maternal effect | recessive
lethal | embryonic stage | recessive
lethal | embryonic stage | recessive | rescuable maternal effect
lethal | recessive
lethal - all die before end of embryonic stage | recessive
lethal - all die before end of pupal stage | somatic clone
lethal - all die during P-stage, with Scer\GAL4Mef2.PR
partially lethal, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
enhancer of variegation | dominant, with P{hsp26-pt-T}39C-5
enhancer of variegation | dominant, with P{hsp26-pt-T}39C-27
enhancer of variegation | dominant, with P{hsp26-pt-T}39C-31
increased cell death | somatic clone
increased cell death | somatic clone | third instar larval stage, with Scer\GAL4Act.PU
neuroanatomy defective | larval stage
neuroanatomy defective | larval stage, with Scer\GAL4GMR9D11
neuroanatomy defective | larval stage, with Scer\GAL4wor.PA
neuroanatomy defective | larval stage | somatic clone
non-enhancer of variegation, with In(1)wm4
non-enhancer of variegation, with P{wA}4-4
non-suppressor of variegation, with In(1)wm4
non-suppressor of variegation, with P{wA}4-4
pain response defective | adult stage, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
short lived | heat sensitive, with Scer\GAL4tin.CΔ4
size defective, with Scer\GAL4en-e16E
some die during embryonic stage | recessive
some die during pupal stage | somatic clone
visible, with Scer\GAL4bi-omb-Gal4
visible, with Scer\GAL4dpp.3KK
visible, with Scer\GAL4en-e16E
visible, with Scer\GAL4ey.PH
visible, with Scer\GAL4ey.PU
visible, with Scer\GAL4MD-638
visible, with Scer\GAL4nub-AC-62
visible, with Scer\GAL4pnr-MD237
visible, with Scer\GAL4salm-459.2
visible, with Scer\GAL4vg.PM
visible | adult stage, with Scer\GAL4en.PU
visible | cell autonomous | somatic clone
visible | dominant
visible | heat sensitive, with Scer\GAL4salm-459.2
visible | male, with Scer\GAL4MD-638
Phenotype manifest in
Allele
denticle | ectopic | germline clone | maternal effect
denticle belt | germline clone
dorsocentral bristle, with Scer\GAL4pnr-MD237
dorsocentral bristle | supernumerary
dorsocentral bristle | supernumerary (with osa4H)
dorsocentral bristle | supernumerary (with osa14060)
embryonic/first instar larval cuticle | germline clone
embryonic/first instar larval cuticle | germline clone | maternal effect
embryonic epidermis | germline clone
embryonic head | germline clone | maternal effect
embryonic segment | germline clone
embryonic segment | germline clone | maternal effect
external sensory organ precursor cell | supernumerary (with osa4H)
external sensory organ precursor cell | supernumerary (with osa14060)
eye, with Scer\GAL4ey.PH
eye, with Scer\GAL4GMR.PF
eye | somatic clone
eye-antennal disc | somatic clone
eye disc, with Scer\GAL4ey.PU
eye disc | somatic clone
ganglion mother cell | larval stage
larval neuroblast | larval stage
leg | somatic clone | supernumerary
leg sensillum | somatic clone | supernumerary
leg ventral compartment | somatic clone
macrochaeta, with Scer\GAL4pnr-MD237
macrochaeta | dorsal, with Scer\GAL4pnr-MD237
macrochaeta | ectopic, with Scer\GAL4pnr-MD237
Malpighian tubule tip cell
mesothoracic tergum | somatic clone
microchaeta, with Scer\GAL4pnr-MD237
microchaeta | dorsal, with Scer\GAL4pnr-MD237
microchaeta | ectopic, with Scer\GAL4pnr-MD237
photoreceptor cell | somatic clone
posterior crossvein, with Scer\GAL4en.PU
pupa, with Scer\GAL4bi-omb-Gal4
retina | somatic clone
scutellar bristle, with Scer\GAL4pnr-MD237
sensillum campaniformium of dorsal radius, with Scer\GAL4bi-omb-Gal4
tarsal segment | somatic clone
thorax, with Scer\GAL4pnr-MD237
type II neuroblast | somatic clone | supernumerary
type II neuroblast | supernumerary, with Scer\GAL4wor.PA
wing
wing, with Scer\GAL4bi-omb-Gal4
wing, with Scer\GAL4en.PU
wing, with Scer\GAL4en-e16E
wing, with Scer\GAL4vg.PM
wing & macrochaeta
wing | ectopic
wing blade | cell autonomous | somatic clone
wing blade anterior compartment | dorsal | somatic clone
wing cell, with Scer\GAL4salm-459.2
wing disc
wing disc | somatic clone
wing hair | cell autonomous | ectopic | somatic clone
wing hair | ectopic, with Scer\GAL4MD-638
wing hair | ectopic, with Scer\GAL4nub-AC-62
wing hair | ectopic | heat sensitive, with Scer\GAL4salm-459.2
wing hinge, with Scer\GAL4vg.PM
wing margin | cell autonomous | somatic clone
wing margin | heat sensitive, with Scer\GAL4salm-459.2
wing margin bristle | ectopic
wing margin bristle | ectopic, with Scer\GAL4bi-omb-Gal4
wing margin bristle | ectopic | somatic clone
wing pouch | somatic clone | third instar larval stage, with Scer\GAL4Act.PU
wing sensillum | cell autonomous | ectopic | somatic clone
wing sensillum | ectopic, with Scer\GAL4MD-638
wing sensillum | ectopic, with Scer\GAL4nub-AC-62
wing sensillum | ectopic | heat sensitive, with Scer\GAL4salm-459.2
wing vein, with Scer\GAL4bi-omb-Gal4
wing vein, with Scer\GAL4dpp.3KK
wing vein, with Scer\GAL4MD-638
wing vein | cell autonomous | somatic clone
wing vein | ectopic, with Scer\GAL4C-765
wing vein | ectopic, with Scer\GAL4en-e16E
wing vein | ectopic, with Scer\GAL4MD-638
wing vein | ectopic, with Scer\GAL4nub-AC-62
wing vein | ectopic, with Scer\GAL4salm-459.2
wing vein | heat sensitive, with Scer\GAL4salm-459.2
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ARID1A
12 of 15
Yes
Yes
Hsap\ARID1B
12 of 15
Yes
Yes
Hsap\ARID3A
2 of 15
No
No
Hsap\ARID3B
2 of 15
No
No
Hsap\ARID3C
2 of 15
No
No
Hsap\ARID4A
1 of 15
No
No
Hsap\ARID4B
1 of 15
No
No
Hsap\ARID5A
1 of 15
No
No
Hsap\ARID5B
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (9)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Arid1a
11 of 15
Yes
Yes
Mmus\Arid1b
11 of 15
Yes
Yes
Mmus\Arid3a
2 of 15
No
No
Mmus\Arid3b
2 of 15
No
No
Mmus\Arid3c
2 of 15
No
No
Mmus\Arid4a
1 of 15
No
No
Mmus\Arid4b
1 of 15
No
No
Mmus\Arid5a
1 of 15
No
No
Mmus\Arid5b
1 of 15
No
No
Rattus norvegicus (Norway rat) (4)
Rnor\Arid1a
7 of 13
Yes
Yes
Rnor\Arid1b
5 of 13
No
Yes
Rnor\Arid3b
1 of 13
No
No
Rnor\Arid3c
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (4)
Xtro\arid1a
7 of 12
Yes
Yes
Xtro\arid1b
6 of 12
No
Yes
Xtro\arid3a
2 of 12
No
No
Xtro\arid3b
1 of 12
No
No
Danio rerio (Zebrafish) (10)
Drer\arid1b
12 of 15
Yes
Yes
Drer\arid1ab
6 of 15
No
Yes
Drer\arid1aa
5 of 15
No
Yes
Drer\arid3b
2 of 15
No
No
Drer\arid3c
2 of 15
No
No
Drer\arid3a
1 of 15
No
No
Drer\arid4a
1 of 15
No
No
Drer\arid4b
1 of 15
No
No
Drer\arid5a
1 of 15
No
No
Drer\arid5b
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (3)
Cele\let-526
11 of 15
Yes
Yes
Cele\cfi-1
2 of 15
No
No
Cele\arid-1
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (5)
Atha\AT1G04880
1 of 9
Yes
Yes
Atha\AT1G55650
1 of 9
Yes
Yes
Atha\AT1G76110
1 of 9
Yes
Yes
Atha\AT3G13350
1 of 9
Yes
Yes
Atha\LFR
1 of 9
Yes
Yes
Saccharomyces cerevisiae (Brewer's yeast) (3)
Scer\ECM5
1 of 15
Yes
No
Scer\RSC9
1 of 15
Yes
No
Scer\SWI1
1 of 15
Yes
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\rsc9
1 of 12
Yes
No
Spom\sol1
1 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091900R9 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00012041
Drosophila simulans
Dsim\GD20218
Drosophila sechellia
Dsec\GM15347
Drosophila erecta
Dere\GG16758
Drosophila yakuba
Dyak\GE27447
Drosophila yakuba
Dyak\osa
Drosophila ananassae
Dana\GF23141
Drosophila pseudoobscura pseudoobscura
Dpse\GA26236
Drosophila persimilis
Dper\GL12242
Drosophila willistoni
Dwil\GK26793
Drosophila willistoni
Dwil\GK22507
Drosophila virilis
Dvir\GJ24712
Drosophila mojavensis
Dmoj\GI23637
Drosophila grimshawi
Dgri\GH15872
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091501ZK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17026026
Glossina morsitans
Tsetse fly
Gmor\GMOY003630
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_12388
Mayetiola destructor
Hessian fly
Mdes\Mdes006443
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL017280
Anopheles darlingi
American malaria mosquito
Adar\ADAC008556
Anopheles gambiae
Malaria mosquito
Agam\AGAP001786
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ010152
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W016J )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA010273
Danaus plexippus
Monarch butterfly
Dple\DPOGS207345-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL002206
Apis florea
Little honeybee
Aflo\2862666676
Apis mellifera
Western honey bee
Amel\GB44899
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP18498
Bombus terrestris
Buff-tailed bumblebee
Bter\15212568
Linepithema humile
Argentine ant
Lhum\LH15859
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0006cf
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG019750
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_09239
Tribolium castaneum
Red flour beetle
Tcas\TC013586
Pediculus humanus
Human body louse
Phum\PHUM080380
Rhodnius prolixus
Kissing bug
Rpro\RPRC005301
Cimex lectularius
Bed bug
Clec\CLEC012210
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006497
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_18729
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X014S )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR006121
Strigamia maritima
European centipede
Smar\SMAR001561
Ixodes scapularis
Black-legged tick
Isca\ISCW014189
Stegodyphus mimosarum
African social velvet spider
Smim\KFM58954.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM78505.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur02g14180
Tetranychus urticae
Two-spotted spider mite
Turt\tetur02g14160
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_327651
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G00GP )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-SwiL
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000014057
Gallus gallus
Domestic chicken
Ggal\ARID1B
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000027551
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000000360
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (3)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
htk
1 of 10
Ir40a
1 of 10
retn
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Model Summary Ribbon
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 2 )
Modifiers Based on Experimental Evidence ( 1 )
Allele
Disease
Interaction
References
osa00090
ameliorates  intellectual disability
modeled by Hsap\MECP2UAS.FL
(Vonhoff et al., 2012)
Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
ARID1A; AT-rich interaction domain 1A
12 of 15
603024
ARID1B; AT-rich interaction domain 1B
12 of 15
614556
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
esyN Network Diagram
Show neighbor-neighbor interactions:
Select Layout:
Legend:
Protein
RNA
Selected Interactor(s)
Interactions Browser
View in Interactions Browser
Please see the Physical Interaction reports below for full details
protein-protein
Physical Interaction
Assay
References
osa - Act5C
anti bait coimmunoprecipitation, molecular weight estimation by staining
(Collins et al., 1999)
osa - Bap111
protein cross-linking with a bifunctional reagent, Identification by mass spectrometry, anti bait coimmunoprecipitation, molecular weight estimation by staining
(Mashtalir et al., 2018, Collins et al., 1999)
osa - Bap55
anti bait coimmunoprecipitation, molecular weight estimation by staining
(Collins et al., 1999)
osa - Bap60
protein cross-linking with a bifunctional reagent, Identification by mass spectrometry, anti bait coimmunoprecipitation, molecular weight estimation by staining, anti tag coimmunoprecipitation, experimental knowledge based
(Mashtalir et al., 2018, Guruharsha et al., 2011, Collins et al., 1999)
osa - CG17002
experimental knowledge based
(Guruharsha et al., 2011)
osa - Cdk8
experimental knowledge based
(Guruharsha et al., 2011)
osa - Chi
nuclear magnetic resonance
(Fiedler et al., 2015)
osa - Cpsf6
experimental knowledge based
(Guruharsha et al., 2011)
osa - CycE
anti bait coimmunoprecipitation, western blot
(Baig et al., 2010)
osa - EcR
proximity-dependent biotin identification, Identification by mass spectrometry, anti bait coimmunoprecipitation, western blot
(Mazina et al., 2020)
osa - Larp4B
experimental knowledge based
(Guruharsha et al., 2011)
osa - MED14
experimental knowledge based
(Guruharsha et al., 2011)
osa - MED17
experimental knowledge based
(Guruharsha et al., 2011)
osa - MED18
experimental knowledge based
(Guruharsha et al., 2011)
osa - MED23
experimental knowledge based
(Guruharsha et al., 2011)
osa - Ptip
experimental knowledge based
(Guruharsha et al., 2011)
osa - Snr1
anti bait coimmunoprecipitation, western blot, molecular weight estimation by staining
(Collins et al., 1999)
osa - Usp10
experimental knowledge based
(Guruharsha et al., 2011)
osa - brm
anti bait coimmunoprecipitation, western blot, peptide massfingerprinting, ion exchange chromatography, molecular sieving, experimental knowledge based
(Nakayama et al., 2012, Guruharsha et al., 2011, Chalkley et al., 2008, Mohrmann et al., 2004, Kal et al., 2000, Collins et al., 1999)
osa - d4
anti tag coimmunoprecipitation, protein cross-linking with a bifunctional reagent, Identification by mass spectrometry
(Mashtalir et al., 2018)
osa - dsh
experimental knowledge based
(Guruharsha et al., 2011)
osa - ebi
experimental knowledge based
(Guruharsha et al., 2011)
osa - mor
anti bait coimmunoprecipitation, peptide massfingerprinting, ion exchange chromatography, molecular sieving, western blot, experimental knowledge based
(Guruharsha et al., 2011, Chalkley et al., 2008, Mohrmann et al., 2004, Collins et al., 1999)
osa - polybromo
protein cross-linking with a bifunctional reagent, Identification by mass spectrometry
(Mashtalir et al., 2018)
osa - sd
anti tag coimmunoprecipitation, anti tag western blot
(Jin et al., 2013)
osa - smt3
anti tag coimmunoprecipitation, comigration in sds page, anti tag western blot
(Pirone et al., 2017)
osa - su(Hw)
anti bait coimmunoprecipitation, western blot
(Vorobyeva et al., 2013)
osa - tna
two hybrid, anti bait coimmunoprecipitation, western blot
(Monribot-Villanueva et al., 2013)
osa - yki
anti bait coimmunoprecipitation, peptide massfingerprinting
(Jin et al., 2013)
osa - z
far western blotting, autoradiography
(Kal et al., 2000)
Summary of Genetic Interactions
esyN Network Diagram
esyN Network Key:
Suppression
Enhancement
View in Interactions Browser
Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
osa
enhanceable
brm
(Gutierrez et al., 2003, Collins et al., 1999)
osa
suppressible
brm
(Collins et al., 1999)
osa
enhanceable
corto
(Lopez et al., 2001)
osa
suppressible
geminin
(Herr et al., 2010)
osa
suppressible
htt
(Dietz et al., 2015)
osa
enhanceable
mor
(Collins et al., 1999)
osa
enhanceable
smt3
(Monribot-Villanueva et al., 2013)
osa
enhanceable
Snr1
(Collins et al., 1999)
osa
enhanceable
tara
(Gutierrez et al., 2003)
osa
enhanceable
tna
(Gutierrez et al., 2003)
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Antp
suppressible
osa
(Ragab et al., 2006, Vazquez et al., 1999)
Antp|Pc
suppressible
osa
(Kennison and Tamkun, 1988)
asf1
suppressible
osa
(Moshkin et al., 2002)
brat
enhanceable
osa
(Janssens et al., 2014)
brm
enhanceable
osa
(Gutierrez et al., 2003, Collins et al., 1999)
bs
suppressible
brm|osa
(Terriente-Félix and de Celis, 2009)
bs
enhanceable
osa
(Terriente-Félix and de Celis, 2009)
Bx
suppressible
osa
(Bejarano et al., 2008, Milan et al., 2004)
Bx
enhanceable
osa
(Bejarano et al., 2008, Milan et al., 2004)
Bx|ap
suppressible
osa
(Bejarano et al., 2008)
Chi
suppressible
osa
(Heitzler et al., 2003)
Chi
enhanceable
osa
(Heitzler et al., 2003)
corto
enhanceable
osa
(Lopez et al., 2001)
ct
suppressible
osa
(Krupp et al., 2005)
ct
enhanceable
osa
(Krupp et al., 2005)
CycE
suppressible
osa
(Brumby et al., 2004, Brumby et al., 2002)
Dp|E2f1
enhanceable
osa
(Staehling-Hampton et al., 1999)
dpp
enhanceable
osa
(Treisman et al., 1997)
Dref
suppressible
osa
(Nakamura et al., 2008, Hirose et al., 2001)
E2f1|Dp
enhanceable
osa
(Staehling-Hampton et al., 1999)
E(z)
enhanceable
osa
(Bajusz et al., 2001)
E(z)
suppressible
osa
(Bajusz et al., 2001)
gcm
enhanceable
brm|osa
(Popkova et al., 2012)
gcm
enhanceable
osa
(Popkova et al., 2012)
gcm
suppressible
osa
(Popkova et al., 2012)
Kr
enhanceable
osa
(Abrell et al., 2000, Carrera et al., 1998)
lz
enhanceable
osa
(Kaminker et al., 2001)
Marcal1
enhanceable
osa
(Morimoto et al., 2016)
Marcal1
suppressible
osa
(Morimoto et al., 2016)
mor
suppressible
osa
(Collins et al., 1999)
net
enhanceable
osa
(Terriente-Félix and de Celis, 2009, Marenda et al., 2004)
net|px
suppressible
brm|osa
(Terriente-Félix and de Celis, 2009)
Pc
suppressible
osa
(Kennison and Tamkun, 1988)
peb
enhanceable
osa
(Wilk et al., 2004)
pnr
enhanceable
osa
(Heitzler et al., 2003)
Ras85D
suppressible
osa
(Terriente-Félix and de Celis, 2009)
Ras85D
enhanceable
osa
(Terriente-Félix and de Celis, 2009)
Ras85D|sev
suppressible
osa
(Maixner et al., 1998)
rl
enhanceable
osa
(Terriente-Félix and de Celis, 2009)
ro
suppressible
osa
(Chanut et al., 2000, Treisman et al., 1997)
sd
enhanceable
osa
(Jin et al., 2013)
sgg
suppressible
osa
(Collins and Treisman, 2000)
sgg
enhanceable
osa
(Collins and Treisman, 2000)
tara
enhanceable
osa
(Gutierrez et al., 2003)
tna
enhanceable
osa
(Monribot-Villanueva et al., 2013, Gutierrez et al., 2003)
tou
suppressible
osa
(Vanolst et al., 2005)
External Data
Subunit Structure (UniProtKB)
Component of the Brahma complex, which is composed of Brm, Osa, Mor, Snr1/Bap45, Bap111/Dalao, Bap55, Bap60 and Bap47. Interacts with Pnr and Chi via its EHD domain.
(UniProt, Q8IN94 )
Linkouts
DroID - A comprehensive database of gene and protein interactions.
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Metabolic Pathways
External Data
Linkouts
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
Genomic Location and Detailed Mapping Data
Chromosome (arm)
3R
Recombination map

3-61

Cytogenetic map
90C1-90C2
Sequence location
3R:17,687,818..17,718,350 [-]
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
90C1-90C2
(determined by in situ hybridisation); Limits computationally determined from genome sequence between P{PZ}l(3)0788207882 and P{EP}cpoEP3679
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
90C1-90C1
(determined by in situ hybridisation)
(Molnar et al., 2006)
Location from complementation analysis with deficiency and duplication chromosomes (details unspecified).
(Kennison and Tamkun, 1988)
90C1-90C2
(Treisman, 1998.3.9)
90C5-90C8
(determined by in situ hybridisation)
(Spradling et al., 1999)
90C1-90C2
(determined by in situ hybridisation)
(Treisman et al., 1997)
90B-90C
(determined by in situ hybridisation)
(Kennison, 1995)
90C5-90C8
90C7--8
(BDGP Project Members, 1994-1999)
90B1-90D1
(Kennison and Tamkun, 1988)
Experimentally Determined Recombination Data
Location

3-61

(FlyBase, 2016)

3-60.2

(Comeron et al., 2012)

3-60.0

(Kennison and Tamkun, 1988)
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (23)
Genomic Clones (35)
cDNA Clones (75)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi and Array Information
Linkouts
DRSC - Results frm RNAi screens
GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Laboratory Generated Antibodies
 

polyclonal

(Eroglu et al., 2014, Vorobyeva et al., 2013, Collins et al., 1999)

monoclonal

(Treisman et al., 1997)
Commercially Available Antibodies
 
Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
Other Information
Relationship to Other Genes
Source for database identify of

Source for identity of: osa CG7467

(Gong, 1999.11)
Source for database merge of

Source for merge of: osa eld

(Vazquez et al., 1999, Maixner et al., 1998)

Source for merge of: osa l(3)j9C3

(Spradling et al., 1999)

Source for merge of: osa C819

(Terriente-Félix and de Celis, 2009)

Source for merge of: osa anon-WO0118547.314 anon-WO0172774.126

(FlyBase, 1996-)
Additional comments

Source for merge of osa anon-WO0118547.314 anon-WO0172774.126 was sequence comparison ( date:051113 ).

(FlyBase, 1996-)

Fails to complement In(3R)Antprv1 for viability.

Other Comments

osa acts as a positive modulator of ap activity in the wing. osa mediates activation of some ap target genes and repression of others.

(Milan et al., 2004)

D.melanogaster contains two distinct brahma (BRM) complexes: the BAP complex, defined by the presence of osa protein and the absence of both polybromo and Bap170 proteins, and the PBAP complex, which contains the polybromo and Bap170 proteins but lacks the osa protein.

(Mohrmann et al., 2004)

osa negatively regulates neural expression of ac/sc.

(Heitzler et al., 2003)

Area matching Drosophila EST AA201670.

(Davies, 2001.3.15)

brm interacts with osa to regulate the expression of the Antp P2 promoter.

(Vazquez et al., 1999)

osa may be involved in signalling through N or wg pathways. osa protein is expressed ubiquitously in the early embryos and in imaginal discs and is localised to the nucleus where results suggests it counteracts the effects of wg on its target genes.

(Treisman et al., 1997)

Mosaic analysis in eye discs suggests a function for osa in cell proliferation and/or survival and neuronal differentiation.

(Treisman et al., 1997)

Mutations in osa enhance the phentype of mutations in brm.

(Vazquez et al., 1995)

Mutations cannot rescue the lethality of the Df(1)ph-2-Psc1 interaction, demonstrating that trx group mutations cannot suppress Pc group phenotypes.

(Cheng et al., 1994)

Dosage-dependent modifier of AntpNs.

(Talbert and Garber, 1994)

Identification: dominant suppressor of the antenna to leg transformation in Pc2 AntpNs double heterozygotes.

(Lindsley and Zimm, 1992)

Dominant suppressor of AntpNs, Pc and Pcl alleles. Recessive embryonic lethality is associated with all alleles.

(Lindsley and Zimm, 1992)

osa is one of the 18 loci identified in a screen for dominant modifiers of Pc and/or Antp phenotypes. Alleles of Pc, Pcl, Scm, Dll, brm, kto, Scr and trx show clear dominant enhancement or suppression of AntpScx, whereas alleles of vtd, Vha55, Su(Pc)37D, urd, mor, skd and osa do not.

(Kennison and Tamkun, 1988)
Origin and Etymology
Discoverer

Kennison, 1983.

Etymology

"osa" means "fate" in Norwegian.

(Kennison, 1995)
Identification
External Crossreferences and Linkouts ( 65 )
Sequence Crossreferences
NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
Other crossreferences
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
FlyMine - An integrated database for Drosophila genomics
GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
InterPro - A database of protein families, domains and functional sites
KEGG Genes - Molecular building blocks of life in the genomic space.
modMine - A data warehouse for the modENCODE project
Linkouts
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results frm RNAi screens
Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
Synonyms and Secondary IDs (16)
Reported As
Symbol Synonym
C819
(Molnar et al., 2006)
CG7467
(Meadows, 2017.1.11, Hosono et al., 2015, Azad et al., 2012, Bridon et al., 2012, Ni et al., 2011.7.19, Ni et al., 2010.12.1, Khokhar et al., 2008, Ni et al., 2008, Molnar et al., 2006, Klebes et al., 2005, Stempfl et al., 2002)
E(E2F)3C
(Staehling-Hampton et al., 1999)
OSA
(Mashtalir et al., 2018, Liu et al., 2017, L Black et al., 2016, Kingston and Tamkun, 2014, Vorobyeva et al., 2013, Moshkin et al., 2012, Schuettengruber et al., 2011, Mills, 2010, Clapier and Cairns, 2009, Moshkin et al., 2009, Soshnikova et al., 2008, Chang et al., 2007, Moshkin et al., 2007, Schwartz and Pirrotta, 2007, Ataman, 2006, Bouazoune and Brehm, 2006, Eberharter and Becker, 2004, Taylor-Harding et al., 2004)
Osa
(Mazina et al., 2020, Rosales-Vega et al., 2018, Liu and Jin, 2017, Liu and Jin, 2017, Monribot-Villanueva et al., 2017, Pirone et al., 2017, Song et al., 2017, Banreti et al., 2014, Bonnay et al., 2014, Eroglu et al., 2014, Waldholm et al., 2011, Baig et al., 2010, Mudiganti et al., 2010, Swaminathan et al., 2010, Glavic et al., 2009, Nie et al., 2009, Vorobyeva et al., 2009, Diop et al., 2008, Martin et al., 2007, Schuettengruber et al., 2007, Secombe et al., 2007, Carrera et al., 2004, Klochendler-Yeivin et al., 2002, Collins et al., 1999)
anon-WO0118547.314
anon-WO0172774.126
eld
(Luschnig et al., 2004, Luschnig et al., 2004, Begun, 2001, Abrell et al., 2000, Begun and Whitley, 2000, Spradling et al., 1999, Thomas and Wassarman, 1999, Collins et al., 1998, Treisman, 1998.3.9, Treisman et al., 1997, Fauvarque et al., 1995)
en(lz)4F/4H
(Kaminker et al., 2001)
eyelid
(Clapier and Cairns, 2009)
l(3)00090
(Carrera et al., 1998)
l(3)04539
(Maixner et al., 1998)
l(3)j9C3
osa
(Chubak et al., 2019, Valanne et al., 2019, Yee et al., 2019, Dasari et al., 2018, Lee et al., 2018, Richardson and Portela, 2018, Rohde et al., 2017, Sharma et al., 2017, Transgenic RNAi Project members, 2017-, Xie et al., 2017, Clandinin and Owens, 2016-, Gene Disruption Project members, 2016-, Morimoto et al., 2016, Testa and Dworkin, 2016, Dietz et al., 2015, Fiedler et al., 2015, Fischer et al., 2015, Gene Disruption Project members, 2015-, Nikalayevich and Ohkura, 2015, Sopko et al., 2015, Wang et al., 2015, Ashwal-Fluss et al., 2014, Bonnay et al., 2014, Eroglu et al., 2014, Janssens et al., 2014, Rogers et al., 2014, Yan et al., 2014, de Celis et al., 2013.9.11, Jin et al., 2013, Monribot-Villanueva et al., 2013, Petruk et al., 2013, Sen et al., 2013, Sen et al., 2013, Vasanthi et al., 2013, Zeng et al., 2013, Antao et al., 2012, Azad et al., 2012, Bridon et al., 2012, Follmer et al., 2012, Hainaut et al., 2012, Japanese National Institute of Genetics, 2012.5.21, Nakayama et al., 2012, Nowak et al., 2012, Popkova et al., 2012, Tokusumi et al., 2012, Valadez-Graham et al., 2012, Vonhoff et al., 2012, Zraly and Dingwall, 2012, Curtis et al., 2011, Di Stefano et al., 2011, Kirilly et al., 2011, Neumüller et al., 2011, Toku et al., 2011, Arancio et al., 2010, Gan et al., 2010, Herr et al., 2010, Salzer et al., 2010, Smulders-Srinivasan et al., 2010, Swaminathan et al., 2010, Ayroles et al., 2009, Schaaf et al., 2009, Terriente-Félix and de Celis, 2009, Carrera et al., 2008, Chalkley et al., 2008, Cukier et al., 2008, Khokhar et al., 2008, Melicharek et al., 2008, Nakamura et al., 2008, Petruk et al., 2008, Remaud et al., 2008, Vázquez et al., 2008, Beltran et al., 2007, Buszczak et al., 2007, Dietzl et al., 2007, Kankel et al., 2007, Dworkin and Gibson, 2006, Dworkin and Gibson., 2006, Molnar et al., 2006, Mathew et al., 2005, Marenda et al., 2003, Hirose et al., 2001)
p300
(Kal et al., 2000)
Name Synonyms
eye lid
(Shandala et al., 1998)
eyelid
(Tulin et al., 2002, Abrell et al., 2000, Bonini and Fortini, 1999, Treisman et al., 1997)
osa
(Salzer et al., 2010, Bejarano et al., 2008, Cukier et al., 2008, Remaud et al., 2008)
Secondary FlyBase IDs
  • FBgn0003013
  • FBgn0010708
  • FBgn0011421
  • FBgn0015384
  • FBgn0046467
  • FBgn0062101
  • FBgn0259443
Datasets (0)
Study focus (0)
Experimental Role
Project
Project Type
Title
References (283)