eld, eyelid, l(3)00090, C819
transcription factor - Bright family - associates with the Brahma chromatin remodeling complex - antagonizes Wingless signaling during Drosophila development and affects patterning of the eye imaginal disc
Please see the JBrowse view of Dmel\osa for information on other features
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Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.
Gene model reviewed during 5.47
10.601 (sequence analysis)
2715 (aa)
Component of the Brahma complex, which is composed of Brm, Osa, Mor, Snr1/Bap45, Bap111/Dalao, Bap55, Bap60 and Bap47. Interacts with Pnr and Chi via its EHD domain.
The ARID domains mediates the binding to DNA.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\osa using the Feature Mapper tool.
Protein was localized along the entire length of all chromosomes. In vitro binding assays showed that osa protein bound DNA without sequence specificity.
GBrowse - Visual display of RNA-Seq signals
View Dmel\osa in GBrowse 23-61
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
monoclonal
Source for identity of: osa CG7467
Source for merge of: osa eld
Source for merge of: osa l(3)j9C3
Source for merge of: osa C819
Source for merge of: osa anon-WO0118547.314 anon-WO0172774.126
Source for merge of osa anon-WO0118547.314 anon-WO0172774.126 was sequence comparison ( date:051113 ).
Fails to complement In(3R)Antprv1 for viability.
Area matching Drosophila EST AA201670.
Mosaic analysis in eye discs suggests a function for osa in cell proliferation and/or survival and neuronal differentiation.
Dosage-dependent modifier of AntpNs.
Kennison, 1983.
"osa" means "fate" in Norwegian.