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Gene Dmel\Ptpmeg

General Information
Symbol	Dmel\Ptpmeg	Species	D. melanogaster
Name	Ptpmeg	Annotation symbol	CG1228
Feature type	protein_coding_gene	FlyBase ID	FBgn0261985
Gene Model Status	Current	Stock availability	32 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	61C1-61C1	Sequence location	3L:328,097..356,050 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Ptpmeg is referred to in FlyBase by the symbol Dmel\Ptpmeg (CG1228, FBgn0261985). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine phosphatase activity; cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process: axon extension involved in axon guidance; mushroom body development; autophagic cell death; salivary gland cell autophagic cell death; central complex development. 45 alleles are reported. The phenotypes of these alleles are annotated with: eye; mushroom body beta-lobe; mushroom body medial lobe; mushroom body vertical lobe; mushroom body alpha-lobe. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Band 4.1 domain; Band 4.1 family; FERM adjacent (FA); FERM central domain; FERM conserved site; FERM domain; FERM, C-terminal PH-like domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; PDZ domain; Pleckstrin homology-like domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, non-receptor type-3, -4; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual specificity phosphatase. Gene sequence location is 3L:328097..356050.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Alleles Ptpmeg[MI08056]
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 61C1-61C1   Limits computationally determined from genome sequence between P{PZ}trh10512 and P{EP}EP3104EP3104
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Ptpmeg for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40 Gene model reviewed during 5.46 DGC clone appears problematic (GH03671): incomplete CDS; LD13416 may be complete, but appears to be an atypical splice variant. Low-frequency RNA-Seq exon junction(s) not annotated. Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Ptpmeg-RG FBtr0306559  NM_138187   3608   974 Ptpmeg-RH FBtr0306560  NM_167831   4116   974 Ptpmeg-RI FBtr0306561  NM_001169838   3596   974 Ptpmeg-RJ FBtr0306562  NM_001169839   4028   974 Ptpmeg-RK FBtr0306563  NM_167830   4079   974
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Ptpmeg-PG   FBpp0297514   109.7   974   7.22     NP_612031   AAN11441 Ptpmeg-PH   FBpp0297515   109.7   974   7.22     NP_728523   AAN11442 Ptpmeg-PI   FBpp0297516   109.7   974   7.22     NP_001163309   ACZ94581 Ptpmeg-PJ   FBpp0297517   109.7   974   7.22     NP_001163310   ACZ94582 Ptpmeg-PK   FBpp0297518   109.7   974   7.22     NP_728522   AAF47380
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein-tyrosine phosphatase, receptor/non-receptor type (IPR000242) FERM domain (IPR000299) Protein-tyrosine/Dual specificity phosphatase (IPR000387) PDZ domain (IPR001478) Pleckstrin homology-like domain (IPR011993) Protein-tyrosine phosphatase, non-receptor type-3, -4 (IPR012151) FERM adjacent (FA) (IPR014847) FERM/acyl-CoA-binding protein, 3-helical bundle (IPR014352) Protein-tyrosine phosphatase, active site (IPR016130) FERM, C-terminal PH-like domain (IPR018980) FERM conserved site (IPR019747) FERM central domain (IPR019748) Band 4.1 family (IPR019750) FERM, N-terminal (IPR018979) Band 4.1 domain (IPR019749)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202459   AA263524   AA438998   AA439681   AA441636   AA536601   AA539126   AA539363   AA817484   AA817641   AA820537   AA820540   AA948831   AA950234   AE014296 AAF47380   AE014296 AAN11441   AE014296 AAN11442   AE014296 ACZ94581   AE014296 ACZ94582   AF217285 AAF44063   AF323978 AAL55993   AI063709   AI109036   AI113868   AI134398   AI294268   AI297904   AI386872   AI519192   AI543004   AI947170   AW942271   AX094087   BF504049   BG638343   BG638396   BG638501   BG638917   BI165686   BI165771   BI171637   BI354238   BI367662   BI367678   BI371174   BI374678   BI375181   BI571892   BI571953   BI591789   BI621872   BI636390   BI638849   BI641918   BP549648   BP551385   BP552310   BT003253 AAO25010   BT004897 AAO47875   BT044533   CK661257   CL844369   CL943596   CL943619   CO187747   CO192029   CO271061   CO284676   CO286958   CO290536   CO290681   CO293798   CO301377   CO307842   CO311980   CO312655   CO315674   CO322816   CO324875   CO326471   CO329354   CO329816   CO331584   CW848185   CZ467878   CZ468203   CZ470084   CZ470119   CZ470574   CZ470576   CZ471051   CZ473284   CZ474496   CZ480886   CZ481882   CZ483534   CZ487559   CZ487969   CZ487970   CZ488854   CZ488868   EC053125   EC053130   EC054103   EC054107   EC056168   EC057035   EC062528   EC063875   EC067330   EC074839   EC076416   EC077751   EC082767   EC090414   EC196080   EC199932   EC204864   EC206605   EC214974   EC227117   EC228765   EC230841   EC233278   EC242302   EC243579   EC260104   GH739903   GH740340   GH740631   GH741259   GH742183   GH742267   GH743596   GH744122   GH746599   GH746649   GH747400   GH747446   GH761512   GH762882   GH763228   GH764469   GH765737   GH766449   GH768165   GH769074   GH769079   GH769696   GH779339   GH942763   GH943363   GH944618   GH946913   GH948155   GH952715   GH955475   GH966259   GH966681   GH966803   GH966817   GH968943   GH969039   GH971115   GH974576   GH978583   GH980916   GH980998   GH981795   GH983080   GH983137   GO254416   GO254447
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W0R3 Q8WSF2 Q86PA5 Q8IRJ0 Q9NHZ3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   antennal primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium central brain primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium visual primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium dorsal head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium lateral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium ventral head epidermis primordium   (Fisher et al., 2012) Comment:reported as procephalic ectoderm primordium organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) ventral epidermis primordium   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal sensory complex proper primordium   (Fisher et al., 2012) Comment:reported as dorsal/lateral sensory complexes embryonic brain   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) sensory nervous system primordium   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012) ventral sensory complex primordium   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    32 central nervous system, pupae P8    32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    40 digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae    49 fat body, pupae P8    34 carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    33 testis, mated 4-day male    28 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (35) central nervous system, larvae L3  (32) central nervous system, pupae P8  (32) head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male  (29) head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering  (40) digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae  (49) fat body, pupae P8  (34) carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female  (41) ovary, mated 4-day female  (33) testis, mated 4-day male  (28) accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    32 central nervous system, pupae P8    32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    40 digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae    49 fat body, pupae P8    34 carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    33 testis, mated 4-day male    28 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    32 central nervous system, pupae P8    32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    40 digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae    49 fat body, pupae P8    34 carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    33 testis, mated 4-day male    28 accessory gland, mated 4-day male    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    32 central nervous system, pupae P8    32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    40 digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae    49 fat body, pupae P8    34 carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    33 testis, mated 4-day male    28 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (35) central nervous system, larvae L3  32 central nervous system, pupae P8  32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male  29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering  (40) digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae  (49) fat body, pupae P8  (34) carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female  (41) ovary, mated 4-day female  (33) testis, mated 4-day male  28 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    32 central nervous system, pupae P8    32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    40 digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae    49 fat body, pupae P8    34 carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    33 testis, mated 4-day male    28 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    35 central nervous system, larvae L3    32 central nervous system, pupae P8    32 head, virgin 1-day female    21 head, virgin 4-day female    23 head, virgin 20-day female    19 head, mated 1-day female    19 head, mated 4-day female    12 head, mated 20-day female    17 head, mated 1-day male    29 head, mated 4-day male    21 head, mated 20-day male    22 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    40 digestive system, 1-day adult    22 digestive system, 4-day adult    20 digestive system, 20-day adult    23 fat body, larvae L3 wandering    21 fat body, white prepupae    49 fat body, pupae P8    34 carcass, larvae L3 wandering    17 carcass, 1-day adult    13 carcass, 4-day adult    12 carcass, 20-day adult    15 ovary, virgin 4-day female    41 ovary, mated 4-day female    33 testis, mated 4-day male    28 accessory gland, mated 4-day male    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    62 embryo 02-04hr    82 embryo 04-06hr    64 embryo 06-08hr    62 embryo 08-10hr    56 embryo 10-12hr    52 embryo 12-14hr    45 embryo 14-16hr    50 embryo 16-18hr    35 embryo 18-20hr    24 embryo 20-22hr    33 embryo 22-24hr    30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    37 white prepupae new    45 white prepupae 12hr    37 white prepupae 24hr    39 pupae 2d postWPP    39 pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day    28 adult male 30day    28 adult female 01day    34 adult female 05day    37 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (62) embryo 02-04hr  (82) embryo 04-06hr  (64) embryo 06-08hr  (62) embryo 08-10hr  (56) embryo 10-12hr  (52) embryo 12-14hr  (45) embryo 14-16hr  (50) embryo 16-18hr  (35) embryo 18-20hr    24 embryo 20-22hr  (33) embryo 22-24hr  (30) larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6  (31) larva L3 puffstage 7-9  (37) white prepupae new  (45) white prepupae 12hr  (37) white prepupae 24hr  (39) pupae 2d postWPP  (39) pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day  (28) adult male 30day  (28) adult female 01day  (34) adult female 05day  (37) adult female 30day  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    62 embryo 02-04hr    82 embryo 04-06hr    64 embryo 06-08hr    62 embryo 08-10hr    56 embryo 10-12hr    52 embryo 12-14hr    45 embryo 14-16hr    50 embryo 16-18hr    35 embryo 18-20hr    24 embryo 20-22hr    33 embryo 22-24hr    30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    37 white prepupae new    45 white prepupae 12hr    37 white prepupae 24hr    39 pupae 2d postWPP    39 pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day    28 adult male 30day    28 adult female 01day    34 adult female 05day    37 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    62 embryo 02-04hr    82 embryo 04-06hr    64 embryo 06-08hr    62 embryo 08-10hr    56 embryo 10-12hr    52 embryo 12-14hr    45 embryo 14-16hr    50 embryo 16-18hr    35 embryo 18-20hr    24 embryo 20-22hr    33 embryo 22-24hr    30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    37 white prepupae new    45 white prepupae 12hr    37 white prepupae 24hr    39 pupae 2d postWPP    39 pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day    28 adult male 30day    28 adult female 01day    34 adult female 05day    37 adult female 30day    40 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    62 embryo 02-04hr    82 embryo 04-06hr    64 embryo 06-08hr    62 embryo 08-10hr    56 embryo 10-12hr    52 embryo 12-14hr    45 embryo 14-16hr    50 embryo 16-18hr    35 embryo 18-20hr    24 embryo 20-22hr    33 embryo 22-24hr    30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    37 white prepupae new    45 white prepupae 12hr    37 white prepupae 24hr    39 pupae 2d postWPP    39 pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day    28 adult male 30day    28 adult female 01day    34 adult female 05day    37 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (62) embryo 02-04hr  (82) embryo 04-06hr  (64) embryo 06-08hr  (62) embryo 08-10hr  (56) embryo 10-12hr  (52) embryo 12-14hr  (45) embryo 14-16hr  (50) embryo 16-18hr  (35) embryo 18-20hr    24 embryo 20-22hr  (33) embryo 22-24hr  30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6  31 larva L3 puffstage 7-9  (37) white prepupae new  (45) white prepupae 12hr  (37) white prepupae 24hr  (39) pupae 2d postWPP  (39) pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day  28 adult male 30day  28 adult female 01day  (34) adult female 05day  (37) adult female 30day  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    62 embryo 02-04hr    82 embryo 04-06hr    64 embryo 06-08hr    62 embryo 08-10hr    56 embryo 10-12hr    52 embryo 12-14hr    45 embryo 14-16hr    50 embryo 16-18hr    35 embryo 18-20hr    24 embryo 20-22hr    33 embryo 22-24hr    30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    37 white prepupae new    45 white prepupae 12hr    37 white prepupae 24hr    39 pupae 2d postWPP    39 pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day    28 adult male 30day    28 adult female 01day    34 adult female 05day    37 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    62 embryo 02-04hr    82 embryo 04-06hr    64 embryo 06-08hr    62 embryo 08-10hr    56 embryo 10-12hr    52 embryo 12-14hr    45 embryo 14-16hr    50 embryo 16-18hr    35 embryo 18-20hr    24 embryo 20-22hr    33 embryo 22-24hr    30 larva L1    16 larva L2    16 larva L3 12hr old    14 larva L3 puffstage 1-2    19 larva L3 puffstage 3-6    31 larva L3 puffstage 7-9    37 white prepupae new    45 white prepupae 12hr    37 white prepupae 24hr    39 pupae 2d postWPP    39 pupae 3d postWPP    22 pupae 4d postWPP    20 adult male 01day    25 adult male 05day    28 adult male 30day    28 adult female 01day    34 adult female 05day    37 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    14 embryonic 1182-4H    36 embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1    29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC    27 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (40) Schneider line 2 Sg4    14 embryonic 1182-4H  (36) embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1  (29) CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC  (27) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    14 embryonic 1182-4H    36 embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1    29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC    27 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    14 embryonic 1182-4H    36 embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1    29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC    27 ovary OSS    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    14 embryonic 1182-4H    36 embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1    29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC    27 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (40) Schneider line 2 Sg4    14 embryonic 1182-4H  (36) embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1  29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC  27 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    14 embryonic 1182-4H    36 embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1    29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC    27 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    40 Schneider line 2 Sg4    14 embryonic 1182-4H    36 embryonic GM2    22 embryonic Kc167    15 embryonic S1    21 embryonic S3    15 leg disc CME L1    19 wing disc CME-W2    13 wing disc ML-DmD8    23 wing disc ML-DmD9    24 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    23 wing disc ML-DmD32    8 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    25 mixed discs ML-DmD4-c1    19 CNS ML-DmBG1-c1    29 CNS ML-DmBG2-c2    11 tumorous blood cells mbn2    14 ovary fGS/OSS    22 ovary OSC    27 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult  (27) Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3  (30) Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult  27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3  30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult  26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    11 heat shock, 4-day adult    16 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    10 Cadmium 50 mM 48 hrs, 4-day adult    15 Cadmium 100 mM 48 hrs, 4-day adult    27 Copper 0.5 mM 12 hrs, larvae L3    12 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    9 Zinc 4.5 mM 48 hrs, 4-day adult    19 Ethanol 2.5% 3 hrs, larvae L3    30 Ethanol 5% 3 hrs, larvae L3    11 Ethanol 10% 3 hrs, larvae L3    8 Caffeine 1.5 mg/ml 4 hrs, larvae L3    10 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    26 Caffeine 25 mg/ml 48 hrs, 4-day adult    15 Paraquat 5 mM 48 hrs, 4-day adult    26 Paraquat 10 mM 48 hrs, 4-day adult    21 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    10 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_30 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD13416
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable Ptpmeg1 Ptpmeg03 PtpmegEY10853 PtpmegEY12179 PtpmegEY13883 PtpmegEY14306 viable, with Scer\GAL4pnr-MD237 PtpmegGD7557 Sterility Allele fertile Ptpmeg1 PtpmegEY10853 PtpmegEY12179 PtpmegEY13883 PtpmegEY14306 Other Phenotypes Allele behavior defective Ptpmeg1 neuroanatomy defective (with Df(3L)ED201) Ptpmeg1 PtpmegNP4498 neuroanatomy defective | recessive Ptpmeg1 visible, with Scer\GAL4GMR.PF PtpmegGS9137 Phenotype manifest in Allele axon & ellipsoid body Ptpmeg1 axon & ellipsoid body (with Df(3L)ED201) Ptpmeg1 axon & mushroom body | somatic clone | cell non-autonomous Ptpmeg1 eye, with Scer\GAL4GMR.PF PtpmegGS9137 mushroom body alpha-lobe Ptpmeg1 mushroom body alpha-lobe (with Df(3L)ED201) Ptpmeg1 PtpmegNP4498 mushroom body beta-lobe Ptpmeg1 mushroom body medial lobe Ptpmeg1 mushroom body vertical lobe Ptpmeg1
Classical Alleles ( 35 )
For All Classical Alleles Show
Allele of Ptpmeg Class Mutagen Stocks Known lesion Ptpmegf01047 piggyBac transposase 2 -- PtpmegNP4498 2 -- Ptpmeg03 1 Yes Ptpmeg1 recombination SCEI endonuclease FLPase gene targeting by homologous recombination 1 Yes Ptpmeg5-SZ-3091 1 -- Ptpmegc06290 piggyBac transposase 1 -- Ptpmegc06293 piggyBac transposase 1 -- Ptpmegc06880 piggyBac transposase 1 -- Ptpmegd03310 P-element activity 1 -- Ptpmegd05374 P-element activity 1 -- Ptpmege03119 piggyBac transposase 1 -- Ptpmege04126 piggyBac transposase 1 -- PtpmegEP3542 1 -- PtpmegEY12179 P-element activity 1 -- PtpmegEY13883 P-element activity 1 -- PtpmegEY14306 P-element activity 1 -- PtpmegEY23549 P-element activity 1 -- Ptpmegf04972 piggyBac transposase 1 -- Ptpmegf06198 piggyBac transposase 1 -- PtpmegG8954 P-element activity 1 -- PtpmegGS3223 1 -- PtpmegGS9137 1 Yes PtpmegMB04912 1 -- PtpmegMI00492 1 -- PtpmegMI03892 1 -- Ptpmegc02341 piggyBac transposase 0 -- Ptpmegc02785 piggyBac transposase 0 -- Ptpmegc05544 piggyBac transposase 0 -- Ptpmegc05591 piggyBac transposase 0 -- PtpmegCPTI100033 piggyBac transposase 0 Yes PtpmegDG23409 P-element activity 0 -- PtpmegEY10853 P-element activity 0 -- Ptpmegf05405 piggyBac transposase 0 -- Ptpmegf06210 piggyBac transposase 0 -- PtpmegMI08056 0 --
Alleles Carried on Transgenic Constructs ( 11 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Ptpmeg Class Mutagen Stocks Known lesion PtpmegGD7557 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes PtpmegGLC01434 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PtpmegHMS01924 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PtpmegKK102294 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes PtpmegC877S.Scer\UAS in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes PtpmegG494A.F494A.Scer\UAS in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes PtpmegR883M.Scer\UAS in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes PtpmegScer\SceI.RS.cWa in vitro construct 0 Yes PtpmegScer\UAS.cWa in vitro construct - regulatory fusion 0 Yes PtpmegY650F.D787A.Scer\UAS in vitro construct - site directed mutagenesis in vitro construct - amino acid replacement 0 Yes PtpmegΔFERM.Scer\UAS in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7557} NA P{KK102294} NA P{TRiP.GLC01434} NA P{TRiP.HMS01924} NA P{UAS-Ptpmeg.C877S} NA P{UAS-Ptpmeg.G494A.F494A} NA P{UAS-Ptpmeg.R883M} NA P{UAS-Ptpmeg.W} NA P{UAS-Ptpmeg.Y650F.D787A} NA P{UAS-Ptpmeg.ΔFERM} NA characterization construct P{FRT(whs.Ptpmeg.Scer\SceI.RS)} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}PtpmegEP3542 NA P{EP}PtpmegG8954 NA P{EPgy2}PtpmegEY10853 NA P{EPgy2}PtpmegEY12179 NA P{EPgy2}PtpmegEY13883 NA P{EPgy2}PtpmegEY14306 NA P{EPgy2}PtpmegEY23549 NA P{GSV1}mthGS3223 NA P{GSV6}PtpmegGS9137 NA P{XP}Ptpmegd03310 NA P{XP}Ptpmegd05374 NA miscellaneous insertions Mi{MIC}PtpmegMI00492 NA Mi{MIC}PtpmegMI03892 NA Mi{MIC}PtpmegMI08056 NA P{RS5}Ptpmeg5-SZ-3091 NA P{UAST-YFP.Rab40}Ptpmeg03 NA P{wHy}PtpmegDG23409 NA PBac{544.SVS-1}PtpmegCPTI100033 NA PBac{PB}Ptpmegc02341 NA PBac{PB}Ptpmegc02785 NA PBac{PB}Ptpmegc05544 NA PBac{PB}Ptpmegc05591 NA PBac{PB}Ptpmegc06290 NA PBac{PB}Ptpmegc06293 NA PBac{PB}Ptpmegc06880 NA PBac{RB}Ptpmege03119 NA PBac{RB}Ptpmege04126 NA PBac{WH}Ptpmegf01047 NA PBac{WH}Ptpmegf04972 NA PBac{WH}Ptpmegf05405 NA PBac{WH}Ptpmegf06198 NA PBac{WH}Ptpmegf06210 NA insertion of enhancer trap binary system Mi{ET1}mthMB04912 No P{GawB}PtpmegNP4498 No
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 5 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
autophagic cell death inferred from expression pattern (Gorski et al., 2003) axon extension involved in axon guidance inferred from mutant phenotype (Whited et al., 2007) central complex development inferred from mutant phenotype (Whited et al., 2007) mushroom body development inferred from mutant phenotype (Whited et al., 2007) salivary gland cell autophagic cell death inferred from expression pattern (Gorski et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
cytoskeletal protein binding inferred from electronic annotation with InterPro:IPR012151 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Goldstein and Gunawardena, 2000) protein tyrosine phosphatase activity inferred from sequence or structural similarity (Edwards et al., 2001) inferred from sequence or structural similarity with UniProtKB:P29074 (Edwards, 1999.12.16) non-traceable author statement (Morrison et al., 2000)
Biological Process
CV term Evidence References
protein dephosphorylation inferred from electronic annotation with InterPro:IPR000242, InterPro:IPR012151 (FlyBase Curators et al., 2004-) inferred from sequence or structural similarity (Edwards et al., 2001) non-traceable author statement (Morrison et al., 2000)
Cellular Component
CV term Evidence References
cytoskeleton inferred from electronic annotation with InterPro:IPR000299 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Ptpmeg allele Gene References unspecified pbl (Gregory et al., 2007)
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0261985 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38059 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q86PA5
Orthologs
OrthoDB Orthologs (48) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG618C6R Dipteran inclusive ortholog search EOG6B5PD6 Insect inclusive ortholog search EOG6QJQH2 Arthropod inclusive ortholog search EOG6W6M9W Metazoa inclusive ortholog search EOG6RFZK9
Orthologs in Drosophila Species (EOG618C6R)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Ptpmeg     Drosophila simulans   Dsim\GD13561 Y   Drosophila sechellia   Dsec\GM14335 Y   Drosophila erecta   Dere\GG14719 Y   Drosophila yakuba   Dyak\GE21082 Y   Drosophila ananassae   Dana\GF24903 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA11530 Y   Drosophila persimilis   Dper\GL16093 Y   Drosophila willistoni   Dwil\GK13061 Y   Drosophila virilis   Dvir\GJ12484 Y   Drosophila mojavensis   Dmoj\GI16737 Y   Drosophila grimshawi   Dgri\GH15457 Y
Orthologs in non-Drosophila Dipterans (EOG6B5PD6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003108   Anopheles gambiae Malaria mosquito  Agam\AGAP007130   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ003699
Orthologs in non-Dipteran Insects (EOG6QJQH2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB44779   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG002894   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH17921   Atta cephalotes Leafcutter ant  Acep\ACEP12763   Camponotus floridanus Florida carpenter ant  Cflo\CFLO17728   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20801   Linepithema humile Argentine ant  Lhum\LH20601   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21824   Solenopsis invicta Red fire ant  Sinv\SINV25434   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008797   Bombyx mori Silkmoth  Bmor\BGIBMGA005255   Pediculus humanus Human body louse  Phum\PHUM004630   Pediculus humanus Human body louse  Phum\PHUM004640   Tribolium castaneum Red flour beetle  Tcas\TC005339
Orthologs in non-Insect Arthropods (EOG6W6M9W)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_197788   Ixodes scapularis Deer tick  Isca\ISCW009425   Ixodes scapularis Deer tick  Isca\ISCW009429
Orthologs in non-Arthropod Metazoa (EOG6RFZK9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\ptp-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009557gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_005885gn   Danio rerio Zebrafish  Drer\ptpn4b   Danio rerio Zebrafish  Drer\ptpn4a   Danio rerio Zebrafish  Drer\ptpn3   Xenopus tropicalis Western clawed frog  Xtro\ptpn3   Xenopus tropicalis Western clawed frog  Xtro\ptpn4   Gallus gallus Domestic chicken  Ggal\PTPN3   Gallus gallus Domestic chicken  Ggal\PTPN4   Mus musculus House mouse  Mmus\Ptpn3   Mus musculus House mouse  Mmus\Ptpn4   Rattus norvegicus Norway rat  Rnor\Ptpn3   Rattus norvegicus Norway rat  Rnor\Ptpn4   Homo sapiens Human  Hsap\PTPN4   Homo sapiens Human  Hsap\PTPN3
Human Orthologs (2)
Gene OMIM HGNC Hsap\PTPN4     Hsap\PTPN3
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13561 Drosophila sechellia Dsec\GM14335 Drosophila erecta Dere\GG14719 Drosophila yakuba Dyak\GE21082 Drosophila ananassae Dana\GF24903 Drosophila pseudoobscura pseudoobscura Dpse\GA11530 Drosophila persimilis Dper\GL16093 Drosophila willistoni Dwil\GK13061 Drosophila virilis Dvir\GJ12484 Drosophila mojavensis Dmoj\GI16737 Drosophila grimshawi Dgri\GH15457
Stocks & Reagents
Stocks Listed in FlyBase ( 32 )
Harvard	- P{XP}Ptpmegd03310 - P{XP}Ptpmegd05374 - PBac{PB}Ptpmegc06293 - PBac{PB}Ptpmegc06880 - PBac{RB}Ptpmege03119 - PBac{RB}Ptpmege04126 - PBac{WH}Ptpmegf01047 - PBac{WH}Ptpmegf04972 - PBac{WH}Ptpmegf06198
VDRC	v103740 P{KK102294}VIE-260B v38651 w1118; P{GD7557}v38651 v38652 w1118; P{GD7557}v38652
	More stocks available...
Genomic Clones ( 1 )
	BACR13F06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 137 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD13416 LD27491 LP01515
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT05329 GH03671 GH07535 GH10358 GH11854 GH17231 GM15693 LD02662 LD06606 LD14314 LD16634 LD17213 LD17365 LD17462 LD24321 LD24325 LD28717 LP07596 LP12347 LP20591 RE05627 RE05727 RE13455 RE53460 RE53478 RE58017 RE62334 RE62934 RH06768 RH07205 RH07275 RH53295 SD09562 SD18051 SD21243 SD25586
Other clones	910 19881 53738 54851 66853 75054 104141 149909 156814 165623 190518 191101 193914 214535.26 bs35h04 CK01.2B.B10 CK01.7A.A12 CK01.38C.F12 CK01.81D.F7 CK01.95C.C12 CK01.96B.D12 CK01.130B.D6 EC32649 EC053125 EC053130 EC054103 EC054107 EC056168 EK032556 EK064416 EK074244 EK074748 EK101847 EK166533 EK180835 EK189002 EK195047 EK204854 EK227552 EK229605 EK255827 EK262141 EK292653 EK293929 EK300605 EP03959 FGM102F09 FGM212E12 FGM218A07 LD22982 LD24152 LD38703 RP01421 RP01429 RP01573 RP001002717 RP001007905 RP001011880 RP001011974 RP001012270 RP001014106 RP001014290 RP001017146 RP001019852 RP001020203 RP001022206 RP001022346 RP001024209 RP001033901 RP001037700 RP001040596 RP001045360 RP001045630 RP001050966 RP001051444 RP001054147 RP001055869 RP004097176 RP004139685 RP004200165 RP004213178 RP004214963 RP004215336 RP004227625 RP004234414 RP004237417 RP004239059 RP004252599 RP004257718 RP004259595 RP004360423 RP004416358 RP004447247 RP004448168 RP004475564 RP004475674 RP004477337 RP004482046
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0261985 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38059
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Ptpmeg CG1228 (FlyBase, 1996-)
Source for database merge of	Source for merge of: Ptpmeg anon-WO0118547.211 (FlyBase, 1996-) Source for merge of: Ptpmeg Meg (Edwards et al., 2001)
Additional comments	Source for merge of Ptpmeg anon-WO0118547.211 was sequence comparison (date:051113). (FlyBase, 1996-) Source for identity of Ptpmeg CG1228 was sequence comparison (date:000327). (FlyBase, 1996-)
Other Comments
	FlyBase curator comment: although GenBank/EMBL/DDBJ: AF323978 refers to Ptpmeg as "split central complex", the ability of a scc allele to complement Ptpmeg phenotypes and to produce full-length Ptpmeg protein suggests that these genes are separate. (Whited et al., 2007) The Ptpmeg product is required for the proper establishment of axon projections in the ellipsoid body and is required for stabilization of already-formed projection patterns in the mushroom body. The phosphatase activity of the protein is needed for these functions. (Whited et al., 2007) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Area matching Drosophila EST AA441636. This EST matches ESTs AA820540 and AA817484. Evidence of alternative splicing. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_138187 NM_167830 NM_167831 NM_001169838 NM_001169839 RefSeq (Proteins) • NP_612031 NP_728522 NP_728523 NP_001163309 NP_001163310 DDBJ / EMBL / GenBank • AA438998 AA441636 AA817484 AA817641 AA948831 AAF44063 AAF47380 AAF47380.2 AAL55993 AAN11441 AAN11441.1 AAN11442 AAN11442.1 AAN11443 AAN11443.1 AAO25010 AAO47875 ACZ94581 ACZ94582 AF217285 AF323978 AI947170 AW942271 AX094087 BG638396 BG638501 BT003253 BT004897 CL844369 CL943596 CL943619 CW848185 CZ467878 CZ468203 CZ470084 CZ470119 CZ470574 CZ470576 CZ471051 CZ473284 CZ474496 CZ480886 CZ481882 CZ483534 CZ487559 CZ487969 CZ487970 CZ488854 CZ488868 Entrez Gene - A searchable database of RefSeq genes. • 38059 UniProtKB/TrEMBL • Q8IRJ0 Q8WSF2 Q9NHZ3 Q9W0R3 Q86PA5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein-tyrosine phosphatase, receptor/non-receptor type (IPR000242) FERM domain (IPR000299) Protein-tyrosine/Dual specificity phosphatase (IPR000387) PDZ domain (IPR001478) Pleckstrin homology-like domain (IPR011993) Protein-tyrosine phosphatase, non-receptor type-3, -4 (IPR012151) FERM adjacent (FA) (IPR014847) FERM/acyl-CoA-binding protein, 3-helical bundle (IPR014352) Protein-tyrosine phosphatase, active site (IPR016130) FERM, C-terminal PH-like domain (IPR018980) FERM conserved site (IPR019747) FERM central domain (IPR019748) Band 4.1 family (IPR019750) FERM, N-terminal (IPR018979) Band 4.1 domain (IPR019749) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD13416
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0261985 DRSC - Results from RNAi screens. • FBgn0261985 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0261985 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38059 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 38059 modMine - Data generated by the modENCODE project. • FBgn0261985 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q86PA5
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	anon-WO0118547.211   CG1228 (Brody et al., 2002, Goldstein and Gunawardena, 2000, Morrison et al., 2000, Laviolette et al., 2005, Keleman et al., 2009.8.5, Yano et al., 2012, Ni et al., 2010.12.1) dMEG1 (Wittwer et al., 2003) Meg   MEG1 (Morrison et al., 2000) ptpmeg (Goossens et al., 2011, Whited et al., 2005, Whited et al., 2007, Hong et al., 2008) Ptpmeg (Whited et al., 2007, Laviolette et al., 2005, Gregory et al., 2007, Hoopfer et al., 2008, Zhang et al., 2007, Nelson et al., 2005, Dworkin et al., 2009, Yano et al., 2012, Kim et al., 2006) PTP-meg (Gregory et al., 2007) scc (Pascual, 2000.11.24)
Name Synonym	Meg   Ptpmeg   split central complex (Pascual, 2000.11.24)
Secondary FlyBase IDs
	FBgn0035133 FBgn0046703 FBgn0062170
References ( 57 )
Generate a list of	All references relating to this gene ( 57 )
List References by type	Research paper  ( 16 ) Supplementary material  ( 8 ) Personal communication to FlyBase  ( 19 ) Abstract  ( 4 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 3 ) Patent  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 3 )
	Yano et al., 2012, J. Neurogenet. 26(1): 53--63 Identification of proteasome components required for apical localization of chaoptin using functional genomics. [FBrf0217843] Goossens et al., 2011, Development 138(8): 1595--1605 The Drosophila L1CAM homolog Neuroglian signals through distinct pathways to control different aspects of mushroom body axon development. [FBrf0213316] Horn et al., 2011, Nat. Methods 8(4): 341--346 Mapping of signaling networks through synthetic genetic interaction analysis by RNAi. [FBrf0213352] Show all research papers ...