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Gene Dmel\mir-981

General Information
Symbol	Dmel\mir-981	Species	D. melanogaster
Name	mir-981 stem loop	Annotation symbol	CR42885
Feature type	miRNA_gene	FlyBase ID	FBgn0262178
Gene Model Status	Current	Stock availability	None publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	2B9-2B9	Sequence location	X:1,682,894..1,682,990 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mir-981 stem loop is referred to in FlyBase by the symbol Dmel\mir-981 (CR42885, FBgn0262178). It is a miRNA_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye; 1st posterior cell; wing. It has one annotated transcript. Gene sequence location is X:1682894..1682990.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 2B9-2B9
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mir-981 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Locations and structures of miRNA models as mapped by miRBase (FBrf0220601).
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt)   mir-981-RM FBtr0304184  NR_047728   97   mir-981-RA FBtr0304185  NR_047729   22
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences	miRBase - the home of microRNA data • MI0005838
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence   Name
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
Expression Clusters
External Data & Images
Linkouts
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4Act5C.PU mir-981Scer\UAS.cSa lethal, with Scer\GAL4Bx-MS1096 mir-981Scer\UAS.cSa lethal, with Scer\GAL4ey.PU mir-981Scer\UAS.cSa lethal, with Scer\GAL4ptc-559.1 mir-981Scer\UAS.T:Disc\RFP lethal | pupal stage, with Scer\GAL4sd-SG29.1 mir-981Scer\UAS.T:Disc\RFP Other Phenotypes Allele visible, with Scer\GAL4Bx-MS1096 mir-981Scer\UAS.T:Disc\RFP visible, with Scer\GAL4dpp.PU mir-981Scer\UAS.T:Disc\RFP Phenotype manifest in Allele 1st posterior cell, with Scer\GAL4dpp.PU mir-981Scer\UAS.T:Disc\RFP eye, with Scer\GAL4ey.PU mir-981Scer\UAS.cSa wing, with Scer\GAL4Bx-MS1096 mir-981Scer\UAS.T:Disc\RFP wing, with Scer\GAL4sd-SG29.1 mir-981Scer\UAS.T:Disc\RFP wing margin, with Scer\GAL4sd-SG29.1 mir-981Scer\UAS.T:Disc\RFP
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of mir-981 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mir-981 Class Mutagen Stocks Known lesion mir-981Scer\UAS.cSa in vitro construct - regulatory fusion 0 Yes mir-981Scer\UAS.T:Disc\RFP in vitro construct 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct M{UAS-mir-981.S} NA P{UAS-DsRed-mir-981.L} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	miRNA_gene (FlyBase Genome Annotators, 2010) nuclear_gene (FlyBase Genome Annotators, 2010)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mir-981 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0262178
Orthologs
OrthoDB Orthologs (0) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search No orthologs identified Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (None identified)
No orthologies identified
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 1 )
	BACR03E12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 12798093
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	New annotation CR42885 (which corresponds to mir-981) in release 5.31 of the genome annotation. (FlyBase Genome Annotators, 2010)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NR_047728 NR_047729 Entrez Gene - A searchable database of RefSeq genes. • 12798093
Other Crossreferences
	miRBase - the home of microRNA data • MI0005838
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0262178 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0262178 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 12798093 modMine - Data generated by the modENCODE project. • FBgn0262178
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	CR42885 (FlyBase Genome Annotators, 2010, ) miR-981 (Liu et al., 2011, Ruby et al., 2007, Stark et al., 2007) mir-981 (Bejarano et al., 2012, FlyBase Genome Annotators, 2010, Schertel et al., 2012, Bejarano et al., 2012)
Name Synonym	mir-981 stem loop
Secondary FlyBase IDs
References ( 10 )
Research paper	Bejarano et al., 2012, Development 139(15): 2821--2831 A genome-wide transgenic resource for conditional expression of Drosophila microRNAs. [FBrf0218840] Marrone et al., 2012, BMC Cell Biol. 13: 26 Dg-Dys-Syn1 signaling in Drosophila regulates the microRNA profile. [FBrf0220581] Schertel et al., 2012, Genetics 192(4): 1543--1552 Functional Characterization of Drosophila microRNAs by a Novel in Vivo Library. [FBrf0220194] Liu et al., 2011, Curr. Biol. 21(22): 1888--1893 The Exoribonuclease Nibbler Controls 3' End Processing of MicroRNAs in Drosophila. [FBrf0216782] Ruby et al., 2007, Genome Res. 17(12): 1850--1864 Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. [FBrf0202916] Stark et al., 2007, Genome Res. 17(12): 1865--1879 Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes. [FBrf0202919]
Supplementary material	Bejarano et al., 2012, Development 139(15): Table S2. Detailed descriptions of miRNA gain-of-function phenotypes. [FBrf0219415] Schertel et al., 2012, Genetics 192(4): Table S1. [FBrf0220719] Sandmann and Cohen, 2007, PLoS ONE 2(11): e1265 Identification of novel Drosophila melanogaster microRNAs, Supplementary Table 1. [FBrf0218393]
FlyBase analysis	FlyBase Genome Annotators, 2010, Changes affecting gene model number or type in release 5.31 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.31 of the annotated D.melanogaster genome. [FBrf0211543]