Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mir-125 using the Feature Mapper tool.
mir-125-miRNA is detected in increasing quantities during larval to pupal transition.
Expression is stronger in adults than in pupae.
The 2 micro RNAs let-7 and mir-125 are coordinately expressed beginning at the time of puparium formation. The stable forms of these RNAs persist into the adult, however, precursor products change their expression at the time of ecdysone pulses during the pupal stage. Both RNAs arise from a single precursor RNA of approximately 500 bp.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mir-125 in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The annotation for mir-125 has been changed in release 5.31 of the genome annotation, so that instead of representing a mature miRNA it now represents the precursor stem loop pre-miRNA. The symbol of the annotation has been changed from CR33314 to CR43029 to reflect this change.
The three microRNAs let-7, mir-125 and mir-100 are co-transcribed as a single polycistronic transcription unit (the "let-7-Complex, let-7-C").
New annotation (CR33314) in release 3.2 of the genome annotation.