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Gene Dmel\Rab8

General Information
Symbol	Dmel\Rab8	Species	D. melanogaster
Name	Rab8	Annotation symbol	CG8287
Feature type	protein_coding_gene	FlyBase ID	FBgn0262518
Gene Model Status	Current	Stock availability	14 publicly available
Also Known As	dm-Rab8, DmRab8, DRab8
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	76D2-76D3	Sequence location	3L:19,860,588..19,864,178 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Rab8 is referred to in FlyBase by the symbol Dmel\Rab8 (CG8287, FBgn0262518). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: protein transport; small GTPase mediated signal transduction. 13 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rab type. Gene sequence location is 3L:19860588..19864178.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03	Controlled Vocabulary Terms synapse neuronal cell body
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 76D2-76D3
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Rab8 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.40 Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Rab8-RA FBtr0074921  NM_079448   2263   207 Rab8-RB FBtr0308832  NM_001259907   1068   172 Rab8-RC FBtr0308833  NM_001259908   2043   207
Additional Transcript Data & Comments
Reported size (kB)	2.2 (longest cDNA) (Satoh et al., 1997)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Rab8-PA   FBpp0074690   23.7   207   8.77     NP_524172   AAF49101 Rab8-PB   FBpp0300989   19.7   172   8.67     NP_001246836   AFH04507 Rab8-PC   FBpp0300990   23.7   207   8.77     NP_001246837   AFH04508
Additional Polypeptide Data & Comments
Reported size (kDa)	207 (aa) (Satoh et al., 1997)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • P-loop containing nucleoside triphosphate hydrolase (IPR027417) Small GTPase superfamily (IPR001806) Small GTPase superfamily, Rab type (IPR003579) Small GTP-binding protein domain (IPR005225)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263192   AA264304   AA390890   AA438655   AA735900   AA816385   AA816473   AA820401   AA941804   AA950233   AA951810   AA990712   AE014296 AAF49101   AB112933 BAD07038   AE014296 AFH04507   AE014296 AFH04508   AI256862   AI512755   AI513608   AI518547   AI543752   AI945594   AW943740   AY069671 AAL39816   BI162893   BI165175   BI166035   BI170235   BI170846   BI171129   BI213180   BI227536   BI227623   BI231263   BI231923   BI231943   BI236629   BI237347   BI238631   BI239172   BI243111   BI357857   BI363674   BI369272   BI369841   BI369879   BI483599   BI566665   BI566790   BI577528   BI578097   BI579017   BI635069   BT124772   CO155522   CO181319   CO187919   CO190591   CO196670   CO266163   CO273166   CO284353   CO286683   CO298451   CO302434   CO305003   CO306292   CO310206   CO318222   CZ467283   CZ480961   CZ482845   CZ482846   CZ485601   CZ485602   D84347 BAA21711   EC060440   EC064629   EC065873   EC066732   EC069051   EC079771   EC085510   EC091186   EC206968   EC217894   EC221894   EC229946   EC237757   EC247296   EC266576   EV576820   EV583041   EV586040   EV588966   EV598510
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	O18338
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   head mesoderm anlage   (Fisher et al., 2012) Comment:anlage in statu nascendi organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) plasmatocyte primordium   (Fisher et al., 2012) Comment:reported as plasmatocytes anlage trunk mesoderm   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) plasmatocyte   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
neuronal cell body inferred from direct assay (Jin et al., 2012) synapse inferred from direct assay (Chan et al., 2011, Jin et al., 2012)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    50 central nervous system, larvae L3    47 central nervous system, pupae P8    60 head, virgin 1-day female    28 head, virgin 4-day female    26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male    30 head, mated 4-day male    33 head, mated 20-day male    40 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    39 digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae    36 fat body, pupae P8    39 carcass, larvae L3 wandering    40 carcass, 1-day adult    37 carcass, 4-day adult    38 carcass, 20-day adult    29 ovary, virgin 4-day female    77 ovary, mated 4-day female    70 testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (50) central nervous system, larvae L3  (47) central nervous system, pupae P8  (60) head, virgin 1-day female  (28) head, virgin 4-day female  26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male  (30) head, mated 4-day male  (33) head, mated 20-day male  (40) salivary gland, larvae L3 wandering    18 salivary gland, white prepupae  (30) digestive system, larvae L3 wandering  (39) digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae  (36) fat body, pupae P8  (39) carcass, larvae L3 wandering  (40) carcass, 1-day adult  (37) carcass, 4-day adult  (38) carcass, 20-day adult  (29) ovary, virgin 4-day female  (77) ovary, mated 4-day female  (70) testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    50 central nervous system, larvae L3    47 central nervous system, pupae P8    60 head, virgin 1-day female    28 head, virgin 4-day female    26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male    30 head, mated 4-day male    33 head, mated 20-day male    40 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    39 digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae    36 fat body, pupae P8    39 carcass, larvae L3 wandering    40 carcass, 1-day adult    37 carcass, 4-day adult    38 carcass, 20-day adult    29 ovary, virgin 4-day female    77 ovary, mated 4-day female    70 testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    50 central nervous system, larvae L3    47 central nervous system, pupae P8    60 head, virgin 1-day female    28 head, virgin 4-day female    26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male    30 head, mated 4-day male    33 head, mated 20-day male    40 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    39 digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae    36 fat body, pupae P8    39 carcass, larvae L3 wandering    40 carcass, 1-day adult    37 carcass, 4-day adult    38 carcass, 20-day adult    29 ovary, virgin 4-day female    77 ovary, mated 4-day female    70 testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    50 central nervous system, larvae L3    47 central nervous system, pupae P8    60 head, virgin 1-day female    28 head, virgin 4-day female    26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male    30 head, mated 4-day male    33 head, mated 20-day male    40 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    39 digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae    36 fat body, pupae P8    39 carcass, larvae L3 wandering    40 carcass, 1-day adult    37 carcass, 4-day adult    38 carcass, 20-day adult    29 ovary, virgin 4-day female    77 ovary, mated 4-day female    70 testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (50) central nervous system, larvae L3  (47) central nervous system, pupae P8  (60) head, virgin 1-day female  28 head, virgin 4-day female  26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male  30 head, mated 4-day male  (33) head, mated 20-day male  (40) salivary gland, larvae L3 wandering    18 salivary gland, white prepupae  30 digestive system, larvae L3 wandering  (39) digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae  (36) fat body, pupae P8  (39) carcass, larvae L3 wandering  (40) carcass, 1-day adult  (37) carcass, 4-day adult  (38) carcass, 20-day adult  29 ovary, virgin 4-day female  (77) ovary, mated 4-day female  (70) testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    50 central nervous system, larvae L3    47 central nervous system, pupae P8    60 head, virgin 1-day female    28 head, virgin 4-day female    26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male    30 head, mated 4-day male    33 head, mated 20-day male    40 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    39 digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae    36 fat body, pupae P8    39 carcass, larvae L3 wandering    40 carcass, 1-day adult    37 carcass, 4-day adult    38 carcass, 20-day adult    29 ovary, virgin 4-day female    77 ovary, mated 4-day female    70 testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    50 central nervous system, larvae L3    47 central nervous system, pupae P8    60 head, virgin 1-day female    28 head, virgin 4-day female    26 head, virgin 20-day female    21 head, mated 1-day female    22 head, mated 4-day female    24 head, mated 20-day female    21 head, mated 1-day male    30 head, mated 4-day male    33 head, mated 20-day male    40 salivary gland, larvae L3 wandering    18 salivary gland, white prepupae    30 digestive system, larvae L3 wandering    39 digestive system, 1-day adult    16 digestive system, 4-day adult    21 digestive system, 20-day adult    17 fat body, larvae L3 wandering    11 fat body, white prepupae    36 fat body, pupae P8    39 carcass, larvae L3 wandering    40 carcass, 1-day adult    37 carcass, 4-day adult    38 carcass, 20-day adult    29 ovary, virgin 4-day female    77 ovary, mated 4-day female    70 testis, mated 4-day male    22 accessory gland, mated 4-day male    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    75 embryo 04-06hr    46 embryo 06-08hr    49 embryo 08-10hr    60 embryo 10-12hr    53 embryo 12-14hr    60 embryo 14-16hr    37 embryo 16-18hr    41 embryo 18-20hr    26 embryo 20-22hr    30 embryo 22-24hr    42 larva L1    22 larva L2    30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    47 white prepupae new    50 white prepupae 12hr    50 white prepupae 24hr    49 pupae 2d postWPP    48 pupae 3d postWPP    29 pupae 4d postWPP    16 adult male 01day    33 adult male 05day    35 adult male 30day    27 adult female 01day    33 adult female 05day    53 adult female 30day    48 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (68) embryo 02-04hr  (75) embryo 04-06hr  (46) embryo 06-08hr  (49) embryo 08-10hr  (60) embryo 10-12hr  (53) embryo 12-14hr  (60) embryo 14-16hr  (37) embryo 16-18hr  (41) embryo 18-20hr  26 embryo 20-22hr  (30) embryo 22-24hr  (42) larva L1    22 larva L2  (30) larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6  (32) larva L3 puffstage 7-9  (47) white prepupae new  (50) white prepupae 12hr  (50) white prepupae 24hr  (49) pupae 2d postWPP  (48) pupae 3d postWPP  (29) pupae 4d postWPP    16 adult male 01day  (33) adult male 05day  (35) adult male 30day  (27) adult female 01day  (33) adult female 05day  (53) adult female 30day  (48) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    75 embryo 04-06hr    46 embryo 06-08hr    49 embryo 08-10hr    60 embryo 10-12hr    53 embryo 12-14hr    60 embryo 14-16hr    37 embryo 16-18hr    41 embryo 18-20hr    26 embryo 20-22hr    30 embryo 22-24hr    42 larva L1    22 larva L2    30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    47 white prepupae new    50 white prepupae 12hr    50 white prepupae 24hr    49 pupae 2d postWPP    48 pupae 3d postWPP    29 pupae 4d postWPP    16 adult male 01day    33 adult male 05day    35 adult male 30day    27 adult female 01day    33 adult female 05day    53 adult female 30day    48 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    75 embryo 04-06hr    46 embryo 06-08hr    49 embryo 08-10hr    60 embryo 10-12hr    53 embryo 12-14hr    60 embryo 14-16hr    37 embryo 16-18hr    41 embryo 18-20hr    26 embryo 20-22hr    30 embryo 22-24hr    42 larva L1    22 larva L2    30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    47 white prepupae new    50 white prepupae 12hr    50 white prepupae 24hr    49 pupae 2d postWPP    48 pupae 3d postWPP    29 pupae 4d postWPP    16 adult male 01day    33 adult male 05day    35 adult male 30day    27 adult female 01day    33 adult female 05day    53 adult female 30day    48 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    75 embryo 04-06hr    46 embryo 06-08hr    49 embryo 08-10hr    60 embryo 10-12hr    53 embryo 12-14hr    60 embryo 14-16hr    37 embryo 16-18hr    41 embryo 18-20hr    26 embryo 20-22hr    30 embryo 22-24hr    42 larva L1    22 larva L2    30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    47 white prepupae new    50 white prepupae 12hr    50 white prepupae 24hr    49 pupae 2d postWPP    48 pupae 3d postWPP    29 pupae 4d postWPP    16 adult male 01day    33 adult male 05day    35 adult male 30day    27 adult female 01day    33 adult female 05day    53 adult female 30day    48 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (68) embryo 02-04hr  (75) embryo 04-06hr  (46) embryo 06-08hr  (49) embryo 08-10hr  (60) embryo 10-12hr  (53) embryo 12-14hr  (60) embryo 14-16hr  (37) embryo 16-18hr  (41) embryo 18-20hr  26 embryo 20-22hr  30 embryo 22-24hr  (42) larva L1    22 larva L2  30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6  32 larva L3 puffstage 7-9  (47) white prepupae new  (50) white prepupae 12hr  (50) white prepupae 24hr  (49) pupae 2d postWPP  (48) pupae 3d postWPP  29 pupae 4d postWPP    16 adult male 01day  (33) adult male 05day  (35) adult male 30day  27 adult female 01day  (33) adult female 05day  (53) adult female 30day  (48) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    75 embryo 04-06hr    46 embryo 06-08hr    49 embryo 08-10hr    60 embryo 10-12hr    53 embryo 12-14hr    60 embryo 14-16hr    37 embryo 16-18hr    41 embryo 18-20hr    26 embryo 20-22hr    30 embryo 22-24hr    42 larva L1    22 larva L2    30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    47 white prepupae new    50 white prepupae 12hr    50 white prepupae 24hr    49 pupae 2d postWPP    48 pupae 3d postWPP    29 pupae 4d postWPP    16 adult male 01day    33 adult male 05day    35 adult male 30day    27 adult female 01day    33 adult female 05day    53 adult female 30day    48 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    68 embryo 02-04hr    75 embryo 04-06hr    46 embryo 06-08hr    49 embryo 08-10hr    60 embryo 10-12hr    53 embryo 12-14hr    60 embryo 14-16hr    37 embryo 16-18hr    41 embryo 18-20hr    26 embryo 20-22hr    30 embryo 22-24hr    42 larva L1    22 larva L2    30 larva L3 12hr old    20 larva L3 puffstage 1-2    23 larva L3 puffstage 3-6    32 larva L3 puffstage 7-9    47 white prepupae new    50 white prepupae 12hr    50 white prepupae 24hr    49 pupae 2d postWPP    48 pupae 3d postWPP    29 pupae 4d postWPP    16 adult male 01day    33 adult male 05day    35 adult male 30day    27 adult female 01day    33 adult female 05day    53 adult female 30day    48 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    44 embryonic GM2    86 embryonic Kc167    51 embryonic S1    48 embryonic S3    45 leg disc CME L1    52 wing disc CME-W2    45 wing disc ML-DmD8    35 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    23 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    42 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    59 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    63 ovary fGS/OSS    30 ovary OSC    36 ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (67) Schneider line 2 Sg4  (47) embryonic 1182-4H  (44) embryonic GM2  (86) embryonic Kc167  (51) embryonic S1  (48) embryonic S3  (45) leg disc CME L1  (52) wing disc CME-W2  (45) wing disc ML-DmD8  (35) wing disc ML-DmD9  (33) wing disc ML-DmD16-c3  (40) wing disc ML-DmD21    23 wing disc ML-DmD32  (34) haltere disc ML-DmD17-c3  (42) eye-antennal disc ML-DmD11  (29) antennal disc ML-DmD20-c5  (35) mixed discs ML-DmD4-c1  (59) CNS ML-DmBG1-c1  (44) CNS ML-DmBG2-c2  (40) tumorous blood cells mbn2  (63) ovary fGS/OSS  (30) ovary OSC  (36) ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    44 embryonic GM2    86 embryonic Kc167    51 embryonic S1    48 embryonic S3    45 leg disc CME L1    52 wing disc CME-W2    45 wing disc ML-DmD8    35 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    23 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    42 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    59 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    63 ovary fGS/OSS    30 ovary OSC    36 ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    44 embryonic GM2    86 embryonic Kc167    51 embryonic S1    48 embryonic S3    45 leg disc CME L1    52 wing disc CME-W2    45 wing disc ML-DmD8    35 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    23 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    42 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    59 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    63 ovary fGS/OSS    30 ovary OSC    36 ovary OSS    19 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    44 embryonic GM2    86 embryonic Kc167    51 embryonic S1    48 embryonic S3    45 leg disc CME L1    52 wing disc CME-W2    45 wing disc ML-DmD8    35 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    23 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    42 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    59 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    63 ovary fGS/OSS    30 ovary OSC    36 ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (67) Schneider line 2 Sg4  (47) embryonic 1182-4H  (44) embryonic GM2  (86) embryonic Kc167  (51) embryonic S1  (48) embryonic S3  (45) leg disc CME L1  (52) wing disc CME-W2  (45) wing disc ML-DmD8  (35) wing disc ML-DmD9  (33) wing disc ML-DmD16-c3  (40) wing disc ML-DmD21    23 wing disc ML-DmD32  (34) haltere disc ML-DmD17-c3  (42) eye-antennal disc ML-DmD11  29 antennal disc ML-DmD20-c5  (35) mixed discs ML-DmD4-c1  (59) CNS ML-DmBG1-c1  (44) CNS ML-DmBG2-c2  (40) tumorous blood cells mbn2  (63) ovary fGS/OSS  30 ovary OSC  (36) ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    44 embryonic GM2    86 embryonic Kc167    51 embryonic S1    48 embryonic S3    45 leg disc CME L1    52 wing disc CME-W2    45 wing disc ML-DmD8    35 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    23 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    42 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    59 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    63 ovary fGS/OSS    30 ovary OSC    36 ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    67 Schneider line 2 Sg4    47 embryonic 1182-4H    44 embryonic GM2    86 embryonic Kc167    51 embryonic S1    48 embryonic S3    45 leg disc CME L1    52 wing disc CME-W2    45 wing disc ML-DmD8    35 wing disc ML-DmD9    33 wing disc ML-DmD16-c3    40 wing disc ML-DmD21    23 wing disc ML-DmD32    34 haltere disc ML-DmD17-c3    42 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    35 mixed discs ML-DmD4-c1    59 CNS ML-DmBG1-c1    44 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    63 ovary fGS/OSS    30 ovary OSC    36 ovary OSS    19 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult    36 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    38 Cadmium 50 mM 48 hrs, 4-day adult    37 Cadmium 100 mM 48 hrs, 4-day adult    57 Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult    58 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    47 Ethanol 2.5% 3 hrs, larvae L3    52 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    65 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    56 Paraquat 10 mM 48 hrs, 4-day adult    50 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult  (36) Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3  (38) Cadmium 50 mM 48 hrs, 4-day adult  (37) Cadmium 100 mM 48 hrs, 4-day adult  (57) Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult  (58) Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult  (47) Ethanol 2.5% 3 hrs, larvae L3  (52) Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (27) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (65) Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult  (56) Paraquat 10 mM 48 hrs, 4-day adult  (50) Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult    36 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    38 Cadmium 50 mM 48 hrs, 4-day adult    37 Cadmium 100 mM 48 hrs, 4-day adult    57 Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult    58 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    47 Ethanol 2.5% 3 hrs, larvae L3    52 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    65 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    56 Paraquat 10 mM 48 hrs, 4-day adult    50 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult    36 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    38 Cadmium 50 mM 48 hrs, 4-day adult    37 Cadmium 100 mM 48 hrs, 4-day adult    57 Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult    58 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    47 Ethanol 2.5% 3 hrs, larvae L3    52 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    65 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    56 Paraquat 10 mM 48 hrs, 4-day adult    50 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult    36 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    38 Cadmium 50 mM 48 hrs, 4-day adult    37 Cadmium 100 mM 48 hrs, 4-day adult    57 Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult    58 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    47 Ethanol 2.5% 3 hrs, larvae L3    52 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    65 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    56 Paraquat 10 mM 48 hrs, 4-day adult    50 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult  (36) Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3  (38) Cadmium 50 mM 48 hrs, 4-day adult  (37) Cadmium 100 mM 48 hrs, 4-day adult  (57) Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult  (58) Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult  (47) Ethanol 2.5% 3 hrs, larvae L3  (52) Ethanol 5% 3 hrs, larvae L3  (34) Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3  27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (65) Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult  (56) Paraquat 10 mM 48 hrs, 4-day adult  (50) Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult    36 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    38 Cadmium 50 mM 48 hrs, 4-day adult    37 Cadmium 100 mM 48 hrs, 4-day adult    57 Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult    58 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    47 Ethanol 2.5% 3 hrs, larvae L3    52 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    65 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    56 Paraquat 10 mM 48 hrs, 4-day adult    50 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    17 cold shock, 4-day adult    15 heat shock, 4-day adult    36 Cadmium 50 mM 6 hrs, larvae L3    17 Cadmium 50 mM 12 hrs, larvae L3    38 Cadmium 50 mM 48 hrs, 4-day adult    37 Cadmium 100 mM 48 hrs, 4-day adult    57 Copper 0.5 mM 12 hrs, larvae L3    8 Copper 15 mM 48 hrs, 4-day adult    58 Zinc 5 mM 12 hrs, larvae L3    11 Zinc 4.5 mM 48 hrs, 4-day adult    47 Ethanol 2.5% 3 hrs, larvae L3    52 Ethanol 5% 3 hrs, larvae L3    34 Ethanol 10% 3 hrs, larvae L3    22 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    65 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    56 Paraquat 10 mM 48 hrs, 4-day adult    50 Rotenone 2 μg 12 hrs, larvae L3    23 Rotenone 8 μg 12 hrs, larvae L3    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_01 mE1_20_mRNA_expression_cluster_02
External Data & Images
Linkouts	BDGP expression data • LD44762
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4pnr-MD237 Rab8GD12520 lethal | pupal stage Rab81 lethal | recessive Rab81 Phenotype manifest in Allele
Classical Alleles ( 6 )
For All Classical Alleles Show
Allele of Rab8 Class Mutagen Stocks Known lesion Rab81 ethyl methanesulfonate 1 Yes Rab8B229 1 -- Rab8c01590 piggyBac transposase 1 -- Rab8e03192 piggyBac transposase 1 -- Rab8f00378 piggyBac transposase 1 -- Rab8f03046 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Rab8 Class Mutagen Stocks Known lesion Rab8Q67L.Scer\UAS.P\T.T:Avic\GFP-YFP in vitro construct - amino acid replacement in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes Rab8Scer\UAS.P\T.T:Avic\GFP-YFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes Rab8T22N.Scer\UAS.P\T.T:Avic\GFP-YFP in vitro construct - amino acid replacement in vitro construct - regulatory fusion in vitro construct - coding region fusion 2 Yes Rab8GD12520 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rab8HMS01363 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rab8JF02669 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Rab8NIG.8287R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)25-21 (Cooper et al., 2010) Df(3L)A23 (Cooper et al., 2010) Df(3L)ash1A16 (Cooper et al., 2010) Df(3L)BSC2 (Cooper et al., 2010) Df(3L)BSC445 (Cooper et al., 2010) Df(3L)ED228 (Cooper et al., 2010) Df(3L)Exel9007 (Cooper et al., 2010) Df(3L)Exel9008 (Cooper et al., 2010) Df(3L)Exel9009 (Cooper et al., 2010) Df(3L)kto2 (Cook, 2008.12.1, Cooper et al., 2010, Zhu et al., 2005) Df(3L)XS411 (Cooper et al., 2010) Df(3L)XS533 (Cooper et al., 2010) Df(3L)XS543 (Cooper et al., 2010) Df(3L)XS572 (Cooper et al., 2010) Df(3L)XS917 (Cooper et al., 2010) Df(3L)XS2182 (Cooper et al., 2010)
Not disrupted in	Df(3L)BSC20 (Cooper et al., 2010) Df(3L)BSC417 (Cooper et al., 2010) Df(3L)ED4799 (Cooper et al., 2010) Df(3L)ED4858 (Cooper et al., 2010) Df(3L)Exel6135 (Cooper et al., 2010) Df(3L)Exel9011 (Cooper et al., 2010) Df(3L)Exel9045 (Cooper et al., 2010) Df(3L)Exel9046 (Cooper et al., 2010) Df(3L)kto22 (Cooper et al., 2010) Df(3L)pipeA13 (Cooper et al., 2010) Df(3L)XS705 (Cooper et al., 2010)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12520} NA P{NIG.8287R} NA P{TRiP.HMS01363} NA P{TRiP.JF02669} NA P{UASp-YFP.Rab8.Q67L} NA P{UASp-YFP.Rab8.T22N} NA P{UASp-YFP.Rab8} NA GAL4 construct PBac{I-SceI(FRT.Rab8-GAL4.ATG(loxP.3xP3-RFP))} No
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{5HPw+}Rab8B229 NA PBac{PB}Rab8c01590 NA PBac{RB}Rab8e03192 NA PBac{WH}Rab8f00378 NA PBac{WH}Rab8f03046 NA
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
neuronal cell body inferred from direct assay (Jin et al., 2012) synapse inferred from direct assay (Chan et al., 2011, Jin et al., 2012)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
GTPase activity inferred from sequence or structural similarity (Jekely, 2003) inferred from sequence or structural similarity with UniProtKB:P70550 (FlyBase, 1992-) non-traceable author statement (Kohno et al., 1994) GTP binding inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579, InterPro:IPR005225 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
protein transport inferred from electronic annotation with InterPro:IPR003579 (FlyBase Curators et al., 2004-) small GTPase mediated signal transduction inferred from electronic annotation with InterPro:IPR001806, InterPro:IPR003579 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
vesicle inferred from sequence or structural similarity with Rab11 (Curators, 2008--)
Sequence Ontology: Class of Gene
	gene (Zhu et al., 2005) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Rab8 - CG1492 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - CG2789 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Rab8 - CG31523 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - CG3303 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - CG7609 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - Pgk anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - RhoL anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - SmD2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - Vps4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - pUf68 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Rab8 - rho anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Rab8 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0262518
Orthologs
OrthoDB Orthologs (144) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6B8K0D Dipteran inclusive ortholog search EOG61NTW5 Insect inclusive ortholog search EOG68W9Z6 Arthropod inclusive ortholog search EOG6J6Q71 Metazoa inclusive ortholog search EOG657J2D
Orthologs in Drosophila Species (EOG6B8K0D)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Rab8     Drosophila simulans   Dsim\GD12244 Y   Drosophila sechellia   Dsec\GM15893 Y   Drosophila erecta   Dere\GG13365 Y   Drosophila yakuba   Dyak\GE22459 Y   Drosophila ananassae   Dana\GF10843 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA23499 Y   Drosophila persimilis   Dper\GL15675 Y   Drosophila willistoni   Dwil\GK17214 Y   Drosophila virilis   Dvir\GJ13999 Y   Drosophila mojavensis   Dmoj\GI13664 Y   Drosophila grimshawi   Dgri\GH16908 Y
Orthologs in non-Drosophila Dipterans (EOG61NTW5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010170   Anopheles gambiae Malaria mosquito  Agam\AGAP001211   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006714
Orthologs in non-Dipteran Insects (EOG68W9Z6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB55960 Y Apis mellifera Western honey bee  Amel\Ame.1740 Y Apis mellifera Western honey bee  Amel\GB52842 Y Apis mellifera Western honey bee  Amel\Rab10 Y Apis mellifera Western honey bee  Amel\Ame.3590 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG011245 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG005975 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG020155 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG001698 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG013952 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH18187 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21022 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10637 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH14030 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11347 Y Atta cephalotes Leafcutter ant  Acep\ACEP16947 Y Atta cephalotes Leafcutter ant  Acep\ACEP19570 Y Atta cephalotes Leafcutter ant  Acep\ACEP13274 Y Atta cephalotes Leafcutter ant  Acep\ACEP10256 Y Atta cephalotes Leafcutter ant  Acep\ACEP16079 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO16737 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17648 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO17855 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21657 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO20753 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL19470 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL18252 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17491 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL20213 Y Linepithema humile Argentine ant  Lhum\LH12803 Y Linepithema humile Argentine ant  Lhum\LH20433 Y Linepithema humile Argentine ant  Lhum\LH20039 Y Linepithema humile Argentine ant  Lhum\LH19264 Y Linepithema humile Argentine ant  Lhum\LH15342 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB16634 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB12411 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB18086 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB17524 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB22967 Y Solenopsis invicta Red fire ant  Sinv\SINV10886 Y Solenopsis invicta Red fire ant  Sinv\SINV24119 Y Solenopsis invicta Red fire ant  Sinv\SINV13339 Y Solenopsis invicta Red fire ant  Sinv\SINV19525 Y Solenopsis invicta Red fire ant  Sinv\SINV17605 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI000150 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001895 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI001670 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI002039 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI086839 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI008058 Y Bombyx mori Silkmoth  Bmor\rabB Y Bombyx mori Silkmoth  Bmor\BGIBMGA004846 Y Bombyx mori Silkmoth  Bmor\BGIBMGA004666 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000295 Y Bombyx mori Silkmoth  Bmor\BGIBMGA002449 Y Pediculus humanus Human body louse  Phum\PHUM042170 Y Pediculus humanus Human body louse  Phum\PHUM046450 Y Pediculus humanus Human body louse  Phum\PHUM450640 Y Tribolium castaneum Red flour beetle  Tcas\TC001149 Y Tribolium castaneum Red flour beetle  Tcas\TC002919 Y Tribolium castaneum Red flour beetle  Tcas\TC014518 Y Tribolium castaneum Red flour beetle  Tcas\TC010990 Y Tribolium castaneum Red flour beetle  Tcas\TC009965 Y
Orthologs in non-Insect Arthropods (EOG6J6Q71)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\CYP2C31 Y Daphnia pulex Water flea  Dpux\JGI_V11_223052 Y Daphnia pulex Water flea  Dpux\JGI_V11_304534 Y Daphnia pulex Water flea  Dpux\JGI_V11_301441 Y Daphnia pulex Water flea  Dpux\JGI_V11_106641 Y Ixodes scapularis Deer tick  Isca\ISCW012427 Y Ixodes scapularis Deer tick  Isca\ISCW003929 Y Ixodes scapularis Deer tick  Isca\ISCW018125 Y Ixodes scapularis Deer tick  Isca\ISCW024874 Y Ixodes scapularis Deer tick  Isca\ISCW012955 Y
Orthologs in non-Arthropod Metazoa (EOG657J2D)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rab-35 Y Caenorhabditis elegans Nematode  Cele\rab-10 Y Caenorhabditis elegans Nematode  Cele\rab-1 Y Caenorhabditis elegans Nematode  Cele\rab-8 Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_002316gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_017072gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009027gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_002399gn Y Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_010762gn Y Danio rerio Zebrafish  Drer\rab8b Y Danio rerio Zebrafish  Drer\rab13 Y Danio rerio Zebrafish  Drer\ENSDARG00000061407 Y Danio rerio Zebrafish  Drer\rab8a Y Danio rerio Zebrafish  Drer\rab1ba Y Danio rerio Zebrafish  Drer\ENSDARG00000046106 Y Danio rerio Zebrafish  Drer\si:ch73-131e21.5 Y Danio rerio Zebrafish  Drer\rab1a Y Danio rerio Zebrafish  Drer\rab35 Y Danio rerio Zebrafish  Drer\ENSDARG00000056479 Y Danio rerio Zebrafish  Drer\ENSDARG00000063142 Y Danio rerio Zebrafish  Drer\zgc:171927 Y Danio rerio Zebrafish  Drer\BX571714.2 Y Xenopus tropicalis Western clawed frog  Xtro\rab1a Y Xenopus tropicalis Western clawed frog  Xtro\LOC100135070 Y Xenopus tropicalis Western clawed frog  Xtro\rab10 Y Xenopus tropicalis Western clawed frog  Xtro\rab35 Y Xenopus tropicalis Western clawed frog  Xtro\MGC75714 Y Xenopus tropicalis Western clawed frog  Xtro\rab8a Y Xenopus tropicalis Western clawed frog  Xtro\rab13 Y Xenopus tropicalis Western clawed frog  Xtro\rab8b Y Gallus gallus Domestic chicken  Ggal\RAB8B Y Gallus gallus Domestic chicken  Ggal\RAB10 Y Gallus gallus Domestic chicken  Ggal\LOC421099 Y Gallus gallus Domestic chicken  Ggal\RAB8A Y Gallus gallus Domestic chicken  Ggal\RAB35 Y Gallus gallus Domestic chicken  Ggal\RAB1A Y Mus musculus House mouse  Mmus\Rab8b Y Mus musculus House mouse  Mmus\Rab8a Y Mus musculus House mouse  Mmus\Rab13 Y Mus musculus House mouse  Mmus\Rab10 Y Mus musculus House mouse  Mmus\Rab35 Y Mus musculus House mouse  Mmus\Rab1b Y Rattus norvegicus Norway rat  Rnor\Rab13 Y Rattus norvegicus Norway rat  Rnor\Rab1 Y Rattus norvegicus Norway rat  Rnor\Rab35 Y Rattus norvegicus Norway rat  Rnor\Rab8b Y Rattus norvegicus Norway rat  Rnor\Rab1b Y Rattus norvegicus Norway rat  Rnor\Rab1b Y Rattus norvegicus Norway rat  Rnor\Rab8a Y Homo sapiens Human  Hsap\RAB8B Y Homo sapiens Human  Hsap\RAB35 Y Homo sapiens Human  Hsap\RAB13 Y Homo sapiens Human  Hsap\RAB1B Y Homo sapiens Human  Hsap\RAB8A Y Homo sapiens Human  Hsap\RAB1A Y Homo sapiens Human  Hsap\RAB10 Y
Human Orthologs (7)
Gene OMIM HGNC Hsap\RAB8B     Hsap\RAB35     Hsap\RAB13     Hsap\RAB1B     Hsap\RAB8A     Hsap\RAB1A     Hsap\RAB10
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12244 Drosophila sechellia Dsec\GM15893 Drosophila erecta Dere\GG13365 Drosophila yakuba Dyak\GE22459 Drosophila ananassae Dana\GF10843 Drosophila pseudoobscura pseudoobscura Dpse\GA23499 Drosophila persimilis Dper\GL15675 Drosophila willistoni Dwil\GK17214 Drosophila virilis Dvir\GJ13999 Drosophila mojavensis Dmoj\GI13664 Drosophila grimshawi Dgri\GH16908
Stocks & Reagents
Stocks Listed in FlyBase ( 14 )
Bloomington	9782 y1 w*; P{UASp-YFP.Rab8}45 27519 y1 v1; P{TRiP.JF02669}attP2 9780 y1 w*; P{UASp-YFP.Rab8.T22N}12 9781 y1 w*; P{UASp-YFP.Rab8.Q67L}05 34373 y1 sc* v1; P{TRiP.HMS01363}attP2 23271 y1 w*; P{UASp-YFP.Rab8.T22N}vimar09/SM6a 23272 y1 w*; P{UASp-YFP.Rab8}CG617509/TM3, Sb1 26173 Rab81 red1 e4/TM6B, Sb1 Tb1 ca1
Harvard	- PBac{PB}Rab8c01590 - PBac{RB}Rab8e03192 - PBac{WH}Rab8f00378
VDRC	v28092 w1118; P{GD12520}v28092/CyO
	More stocks available...
Genomic Clones ( 2 )
	BACR01B21 BACR13N10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 82 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD44762
Other clones	DPiM_LD44762 MIP21873
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM10063 LD01330 LD01884 LD06285 LD07515 LD11733 LD12974 LD23991 LD26010 LD28715 LD32534 LD34547 LD38092 LD45802 LP03511 RE02165 RE05006 RE06055 RE11626 RE12446 RE12815 RE18529 RE20709 RE24614 RE24726 RE25105 RE25126 RE32708 RE33563 RE35135 RE35588 RE40667 RE44451 RE48589 RE55394 RE56156 RE56211 RE66516 RE71221 RE71901 RE72981 RH36374 RH36537 SD10645 SD16307
Other clones	10156 35046 55745 76104 98065 124404 144795 165768 524956 bs14f02 CK01.1C.F4 CK01.2C.D10 CK01.32D.F1 CK01.60C.D10 Dmel_dig_005029_0594_2262 Dmel_dig_005424_0647_0575 Dmel_dig_016738_0631_3469 Dmel_neb_012794_0921_1387 Dmel_neb_014667_0169_2726 EC14038 EK007235 EK034840 EK048747 EK063547 EK109862 EK145163 EK165852 EK173035 EK184136 EK220746 EK246915 EK250720 EK271103 EN06240
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0262518 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40168
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Rab8 l(3)76BDu (Cooper et al., 2010)
Additional comments
Other Comments
	dsRNA has been made from templates generated with primers directed against this gene. (Kouranti et al., 2006) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003) Isolated from a Drosophila head cDNA library. (Satoh et al., 1997)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079448 NM_001259907 NM_001259908 RefSeq (Proteins) • NP_524172 NP_001246836 NP_001246837 DDBJ / EMBL / GenBank • AA264304 AAF49101 AAL39816 AB112933 AFH04507 AFH04508 AI512755 AI945594 AW943740 AY069671 BAA21711 BAD07038 CZ467283 CZ480961 CZ482845 CZ482846 CZ485601 CZ485602 D84347 Entrez Gene - A searchable database of RefSeq genes. • 40168 UniProtKB/TrEMBL • O18338
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • P-loop containing nucleoside triphosphate hydrolase (IPR027417) Small GTPase superfamily (IPR001806) Small GTPase superfamily, Rab type (IPR003579) Small GTP-binding protein domain (IPR005225) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD44762
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0262518 DRSC - Results from RNAi screens. • FBgn0262518 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0262518 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 40168 modMine - Data generated by the modENCODE project. • FBgn0262518
Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	AAF49101 (Armstrong, 2000) CG8287 (Verstreken and Bellen, 2000.9.4, Zhang et al., 2007, Sinka et al., 2008, Perkins et al., 2009, Li et al., 2010, Ni et al., 2010.12.1, Colicelli, 2004) dm-Rab8 (Fukuda et al., 2004, Fukuda, 2004) Dm Rab8 (Jekely, 2003) DmRab8 (Pereira-Leal and Seabra, 2001, Pereira-Leal and Seabra, 2001) DRab8 (Satoh et al., 1997) DRAB8 (Kohno et al., 1994) l(3)76BDu (Cooper et al., 2010, ) O18338 (Rojas et al., 2012) Rab8 (Giagtzoglou et al., 2012, Callejo et al., 2011, Liebl and Featherstone, 2008, Hazelett et al., 2012, Cooper et al., 2010, Kouranti et al., 2006, Cermelli et al., 2006, Stuart et al., 2007, Zhang et al., 2007, Zhang et al., 2007, Cook, 2008.12.1, Sinka et al., 2008, Haghnia et al., 2007, Warner and Longmore, 2009, Akimana et al., 2010, Wu et al., 2005, Japanese National Institute of Genetics, 2012.5.21) rab8 (Chan et al., 2011, Mudiganti et al., 2010, Ozaki, 1996.4.9, Fukuda, 2003.6.21, Jin et al., 2012) Rab-r8
Name Synonym	l(3)76BDu   Rab8   Rab-protein 8
Secondary FlyBase IDs
	FBgn0015796 FBgn0084975
References ( 64 )
Generate a list of	All references relating to this gene ( 64 )
List References by type	Research paper  ( 26 ) Supplementary material  ( 9 ) Review  ( 3 ) Personal communication to FlyBase  ( 14 ) Abstract  ( 3 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 2 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 7 )
	Lindsley et al., 2013, PLoS ONE 8(2): e55915 Anent the Genomics of Spermatogenesis in Drosophila melanogaster. [FBrf0220812] Giagtzoglou et al., 2012, J. Cell Biol. 196(1): 65--83 dEHBP1 Controls Exocytosis and Recycling of Delta During Asymmetric Divisions. [FBrf0217836] Hazelett et al., 2012, G3 (Bethesda) 2(7): 789--802 Comparison of Parallel High-Throughput RNA Sequencing Between Knockout of TDP-43 and Its Overexpression Reveals Primarily Nonreciprocal and Nonoverlapping Gene Expression Changes in the Central Nervous System of Drosophila. [FBrf0219102] Jin et al., 2012, PLoS ONE 7(7): e40912 Similarities of Drosophila rab GTPases Based on Expression Profiling: Completion and Analysis of the rab-Gal4 Kit. [FBrf0219021] Callejo et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(31): 12591--12598 Feature Article: From the Cover: Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium. [FBrf0214615] Chan et al., 2011, Curr. Biol. 21(20): 1704--1715 Systematic discovery of rab GTPases with synaptic functions in Drosophila. [FBrf0216517] Uytterhoeven et al., 2011, Cell 145(1): 117--132 Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteins. [FBrf0213384] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...