FB2022_02, released March 29, 2022

Gene: Dmel\Nuak

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General Information
Symbol
Dmel\Nuak
Species
D. melanogaster
Name
Nuak family kinase
Annotation Symbol
CG43143
Feature Type
protein_coding_gene
FlyBase ID
FBgn0262617
Gene Model Status
Current
Stock Availability
17 publicly available
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Also Known As

Nuak1

Key Links
Genomic Location
Cytogenetic map
86A3-86A6
Sequence location
Recombination map
3-49
RefSeq locus
NT_033777 REGION:10264306..10308467
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (6 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables ATP binding
inferred from electronic annotation with InterPro:IPR000719, InterPro:IPR002290, InterPro:IPR017441
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
enables protein serine/threonine kinase activity
inferred from sequence or structural similarity with HGNC:14311
(FlyBase Curators, 2008-)
enables structural molecule activity
inferred from electronic annotation with InterPro:IPR017404
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Biological Process (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in protein phosphorylation
inferred from sequence or structural similarity with HGNC:14311
(FlyBase Curators, 2008-)
Cellular Component (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
located_in cytoplasm
inferred from sequence or structural similarity with HGNC:14311
(FlyBase Curators, 2008-)
located_in nucleus
inferred from sequence or structural similarity with HGNC:14311
(FlyBase Curators, 2008-)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASES -
The Calcium/Calmodulin-dependent kinase family are serine/threonine kinases which, in general, prefer substrates containing basic residues. Many, but not all, members are regulated by calcium or calmodulin. (Adapted from FBrf0132098).
Gene Model and Products
Number of Transcripts
17
Number of Unique Polypeptides
10

Please see the JBrowse view of Dmel\Nuak for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure New Section
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry A0A6H2EG35)

If you don't see the viewer to the right, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Comments on Gene Model

Gene model reviewed during 5.48

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.49

Stop-codon suppression (UGA) postulated; FBrf0243886.

Gene model reviewed during 6.32

Sequence Ontology: Class of Gene
gene_with_stop_codon_read_through
(FlyBase Genome Annotators, 2020, FlyBase Genome Annotators, 2019-)
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
Nuak-RA
FBtr0305352
NM_141734
4588
1427
Nuak-RB
FBtr0305354
NM_169337
5076
1427
Nuak-RC
FBtr0305353
NM_206470
4793
1427
Nuak-RD
FBtr0305351
NM_206469
5997
1180
Nuak-RE
FBtr0305355
NM_141736
8836
2537
Nuak-RF
FBtr0305356
NM_001260090
5918
1532
Nuak-RG
FBtr0305357
NM_001260091
5566
1199
Nuak-RH
FBtr0337049
NM_001275528
5525
1551
Nuak-RI
FBtr0337050
NM_001275529
9381
2556
Nuak-RJ
FBtr0479807
NM_001382098
9324
2618
Nuak-RK
FBtr0479808
NM_001382099
5177
1285
Nuak-RL
FBtr0479809
NM_001382100
8874
2537
Nuak-RM
FBtr0479810
NM_001382101
10122
2803
Nuak-RN
FBtr0479811
NM_001382102
9324
2537
Nuak-RO
FBtr0479812
NM_001382103
5975
1551
Nuak-RP
FBtr0479813
NM_001382104
5468
1532
Nuak-RQ
FBtr0479814
NM_001382105
4727
1285
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
Nuak-PA
FBpp0293891
153.4
1427
9.08
NP_649991
AAF54516
Nuak-PB
FBpp0293893
153.4
1427
9.08
NP_731469
AAF54517
Nuak-PC
FBpp0293892
153.4
1427
9.08
NP_996192
AAS65134
Nuak-PD
FBpp0293890
127.7
1180
8.33
NP_996191
AAS65135
Nuak-PE
FBpp0293894
274.9
2537
9.94
NP_649993
AAF54518
Nuak-PF
FBpp0293895
163.9
1532
9.50
NP_001247019
AFH06337
Nuak-PG
FBpp0293896
130.0
1199
8.55
NP_001247020
AFH06338
Nuak-PH
FBpp0307978
166.1
1551
9.57
NP_001262457
AGB95839
Nuak-PI
FBpp0307979
277.2
2556
9.96
NP_001262458
AGB95840
Nuak-PJ
FBpp0428140
283.6
2618
9.97
QJC18451
Nuak-PK
FBpp0428141
138.2
1285
9.08
QJC18452
Nuak-PL
FBpp0428142
274.9
2537
9.94
QJC18453
Nuak-PM
FBpp0428143
302.9
2803
9.99
QJC18454
Nuak-PN
FBpp0428144
274.9
2537
9.94
QJC18455
Nuak-PO
FBpp0428145
166.1
1551
9.57
QJC18456
Nuak-PP
FBpp0428146
163.9
1532
9.50
QJC18457
Nuak-PQ
FBpp0428147
138.2
1285
9.08
QJC18458
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1427 aa isoforms: Nuak-PA, Nuak-PB, Nuak-PC
2537 aa isoforms: Nuak-PE, Nuak-PL, Nuak-PN
1532 aa isoforms: Nuak-PF, Nuak-PP
1551 aa isoforms: Nuak-PH, Nuak-PO
1285 aa isoforms: Nuak-PK, Nuak-PQ
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Nuak using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\Nuak in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 18 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 13 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of Nuak
Transgenic constructs containing regulatory region of Nuak
Aberrations (Deficiencies and Duplications) ( 1 )
Inferred from experimentation ( 1 )
Gene disrupted in
Df(3R)Exel6156
(Ryder, 2004.4.26)
Inferred from location ( 0 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal - all die during P-stage, with Scer\GAL4Mef2.PR
partially lethal, with Scer\GAL4tin.CΔ4
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4pnr-MD237
Sterility
Allele
female semi-sterile, with Scer\GAL4VP16.mat.αTub67C
Other Phenotypes
Allele
abnormal body size | P-stage
abnormal body size | P-stage, with Scer\GAL4da.PU
abnormal body size | P-stage, with Scer\GAL4how-24B
abnormal body size | P-stage, with Scer\GAL4Mef2.PR
abnormal body size | P-stage (with Df(3R)BSC479)
abnormal locomotor behavior | third instar larval stage
abnormal locomotor behavior | third instar larval stage, with Scer\GAL4Mef2.PR
decreased size | P-stage
flightless, with Scer\GAL4Mef2.PR
increased mortality during development | calorie restriction conditional
Phenotype manifest in
Allele
anterior pupal spiracle | larval stage
embryonic/larval hypodermal muscle cell | larval stage
embryonic/larval hypodermal muscle cell | larval stage, with Scer\GAL4Mef2.PR
embryonic/larval hypodermal muscle cell | third instar larval stage, with Scer\GAL4Mef2.PR
mitochondrial crista | larval stage
mitochondrion | larval stage
muscle cell of ventral longitudinal muscle 3 | larval stage
muscle cell of ventral longitudinal muscle 3 | larval stage, with Scer\GAL4Mef2.PR
myofibril, with Scer\GAL4Mef2.PR
sarcomere, with Scer\GAL4Mef2.PR
sarcomere | increased number | larval stage, with Scer\GAL4Mef2.PR
ventral longitudinal muscle cell | larval stage
Z disc, with Scer\GAL4Mef2.PR
Z disc | larval stage
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (11)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\NUAK1
6 of 15
Yes
Yes
Hsap\NUAK2
5 of 15
No
Yes
Hsap\BRSK1
1 of 15
No
No
Hsap\BRSK2
1 of 15
No
No
Hsap\HUNK
1 of 15
No
Yes
Hsap\LAD1
1 of 15
No
Yes
Hsap\PRKAA1
1 of 15
No
No
2  
Hsap\SIK1B
1 of 15
No
No
Hsap\SIK1
1 of 15
No
No
Hsap\TSSK3
1 of 15
No
No
Hsap\TSSK6
1 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (11)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Nuak1
6 of 15
Yes
Yes
Mmus\Nuak2
5 of 15
No
Yes
Mmus\Brsk1
1 of 15
No
No
Mmus\Brsk2
1 of 15
No
No
Mmus\Hunk
1 of 15
No
Yes
Mmus\Lad1
1 of 15
No
Yes
Mmus\Prkaa1
1 of 15
No
No
Mmus\Sik1
1 of 15
No
No
Mmus\Srrm2
1 of 15
No
No
Mmus\Tssk3
1 of 15
No
No
Mmus\Tssk6
1 of 15
No
No
Rattus norvegicus (Norway rat) (10)
Rnor\Nuak1
4 of 13
Yes
Yes
Rnor\Nuak2
3 of 13
No
Yes
Rnor\Brsk1
1 of 13
No
No
Rnor\Hunk
1 of 13
No
Yes
Rnor\Lad1
1 of 13
No
Yes
Rnor\Map4
1 of 13
No
No
Rnor\Prkaa1
1 of 13
No
No
Rnor\Sik1
1 of 13
No
No
Rnor\Tssk3
1 of 13
No
No
Rnor\Tssk6
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (5)
Xtro\nuak2
4 of 12
Yes
Yes
Xtro\nuak1
2 of 12
No
Yes
Xtro\brsk1
1 of 12
No
No
Xtro\brsk2
1 of 12
No
No
Xtro\prkaa1
1 of 12
No
No
Danio rerio (Zebrafish) (15)
Drer\nuak1a
5 of 15
Yes
Yes
Drer\nuak2
5 of 15
Yes
Yes
Drer\nuak1b
4 of 15
No
Yes
Drer\brsk2a
1 of 15
No
No
Drer\brsk2b
1 of 15
No
No
Drer\camkvl
1 of 15
No
No
Drer\lad1
1 of 15
No
Yes
Drer\nim1k
1 of 15
No
No
Drer\prkaa1
1 of 15
No
No
Drer\si:ch211-22d5.2
1 of 15
No
No
Drer\si:ch211-255p10.4
1 of 15
No
No
Drer\si:dkey-16p21.7
1 of 15
No
No
Drer\sik1
1 of 15
No
No
Drer\snrkb
1 of 15
No
No
Drer\tssk6
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (5)
Cele\unc-82
3 of 15
Yes
Yes
Cele\aak-2
1 of 15
No
No
Cele\C27D6.11
1 of 15
No
No
Cele\tag-344
1 of 15
No
No
Cele\Y38H8A.4
1 of 15
No
No
Arabidopsis thaliana (thale-cress) (0)
No records found.
Saccharomyces cerevisiae (Brewer's yeast) (13)
Scer\FRK1
1 of 15
Yes
Yes
Scer\HAL5
1 of 15
Yes
No
Scer\KIN1
1 of 15
Yes
No
Scer\KIN2
1 of 15
Yes
No
Scer\KIN4
1 of 15
Yes
No
Scer\KKQ8
1 of 15
Yes
No
Scer\NPR1
1 of 15
Yes
No
Scer\PRR2
1 of 15
Yes
No
Scer\PTK1
1 of 15
Yes
No
Scer\PTK2
1 of 15
Yes
No
Scer\SKS1
1 of 15
Yes
No
Scer\SNF1
1 of 15
Yes
No
Scer\VHS1
1 of 15
Yes
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\fin1
1 of 12
Yes
No
Other Organism Orthologs (via OrthoDB)
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (8)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
AMPKα
1 of 10
CG4629
1 of 10
CG8485
1 of 10
CG9222
1 of 10
CG10177
1 of 10
CG14305
1 of 10
sff
1 of 10
Sik2
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 2 )
    Allele
    Disease
    Interaction
    References
    NuakGD7410
    ameliorates  tauopathy
    modeled by Hsap\MAPTUAS.cUa
    (Lasagna-Reeves et al., 2016)
    NuakEY22355
    exacerbates  tauopathy
    modeled by Hsap\MAPTUAS.cUa
    (Lasagna-Reeves et al., 2016)
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    NUAK1; NUAK family kinase 1
    6 of 15
    608130
        NUAK2; NUAK family kinase 2
        5 of 15
        608131
          Functional Complementation Data
          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
          Interactions
          Summary of Physical Interactions
          esyN Network Diagram
          Show neighbor-neighbor interactions:
          Select Layout:
          Legend:
          Protein
          RNA
          Selected Interactor(s)
          Interactions Browser
          View in Interactions Browser
          Please see the Physical Interaction reports below for full details
          protein-protein
          Physical Interaction
          Assay
          References
          Nuak - cher
          two hybrid
          (Brooks et al., 2020)
          Nuak - stv
          two hybrid
          (Brooks et al., 2020)
          Summary of Genetic Interactions
          esyN Network Diagram
          esyN Network Key:
          Suppression
          Enhancement
          View in Interactions Browser
          Please look at the allele data for full details of the genetic interactions
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Nuak
          suppressible
          stv
          (Brooks et al., 2020)
          Nuak
          enhanceable
          stv
          (Brooks et al., 2020)
          Starting gene(s)
          Interaction type
          Interacting gene(s)
          Reference
          Atg8a
          enhanceable
          Nuak
          (Brooks et al., 2020)
          stv
          enhanceable
          Nuak
          (Brooks et al., 2020)
          External Data
          Linkouts
          DroID - A comprehensive database of gene and protein interactions.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Pathways
          Signaling Pathways (FlyBase)
          Metabolic Pathways
          External Data
          Linkouts
          Genomic Location and Detailed Mapping Data
          Chromosome (arm)
          3R
          Recombination map
          3-49
          Cytogenetic map
          86A3-86A6
          Sequence location
          FlyBase Computed Cytological Location
          Cytogenetic map
          Evidence for location
          86A3-86A6
          Limits computationally determined from genome sequence between P{EP}Fmr1EP3517&P{PZ}tws02414 and P{PZ}jumu06439&P{lacW}l(3)j8B6j8B6
          Experimentally Determined Cytological Location
          Cytogenetic map
          Notes
          References
          Experimentally Determined Recombination Data
          Location

          3-49

          (FlyBase, 2016)

          3-46.6

          (Comeron et al., 2012)
          Left of (cM)
          Right of (cM)
          Notes
          Stocks and Reagents
          Stocks (17)
          Genomic Clones (19)
          cDNA Clones (70)
           

          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

          cDNA clones, fully sequenced
          BDGP DGC clones
          Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of

          Source for identity of: Nuak1 CG43143

          (Lasagna-Reeves et al., 2016)

          Source for identity of: Nuak Nuak1

          (Brooks et al., 2020)
          Source for database merge of

          Source for merge of: CG11870 CG11871

          (FlyBase Genome Annotators, 2002-2003)

          Source for merge of: CG11870 CG11872

          (FlyBase Genome Annotators, 2011)
          Additional comments

          FlyBase curator comment: The D. melanogaster genome appears to contain a single ortholog of the mammalian NUAK1 and NUAK2 genes (represented by the CG43143 annotation). For this reason the gene corresponding to the CG43143 annotation has been renamed to 'Nuak' (from 'Nuak1').

          (Brooks et al., 2020)

          Gene is named 'Nuak1' based on orthology to human gene.

          (Lasagna-Reeves et al., 2016)

          Annotations CG11870 and CG11872 merged as CG43143 in release 5.33 of the genome annotation.

          (FlyBase Genome Annotators, 2011)

          Annotations CG11870 and CG11871 merged as CG11870 in release 3 of the genome annotation.

          (FlyBase Genome Annotators, 2002-2003)
          Other Comments

          dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.

          (Kiger et al., 2003)
          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 87 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          SignaLink - A signaling pathway resource with multi-layered regulatory networks.
          Linkouts
          DroID - A comprehensive database of gene and protein interactions.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Synonyms and Secondary IDs (12)
          Datasets (8)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (8)
          Result
          Result Type
          Title
          scRNAseq_2020_Cattenoz_NI_seq_clustering
          Clustering analysis of hemocytes from non-infested third instar larvae
          scRNAseq_2020_Cattenoz_WI_seq_clustering
          Clustering analysis of hemocytes from wasp-infested third instar larvae
          scRNAseq_2020_Cho_NI72LG_seq_clustering
          Clustering analysis of lymph gland cells from non-infested larvae at 72 h after egg-laying
          scRNAseq_2020_Cho_NI96LG_seq_clustering
          Clustering analysis of lymph gland cells from non-infested larvae at 96 h after egg-laying
          scRNAseq_2020_Cho_NI120LG_seq_clustering
          Clustering analysis of lymph gland cells from non-infested larvae at 120 h after egg-laying
          scRNAseq_2020_Cho_WI96LG_seq_clustering
          Clustering analysis of lymph gland cells from wasp-infested larvae at 96 h after egg-laying
          scRNAseq_2020_Cho_NI96HL_seq_clustering
          Clustering analysis of circulating hemocytes from non-infested larvae at 96 h after egg-laying
          scRNAseq_2020_Cho_NI120HL_seq_clustering
          Clustering analysis of circulating hemocytes from non-infested larvae at 120 h after egg-laying
          References (65)