Arp66B, schwachling, Actr66B, Actin-related protein 66B
AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Component of the Arp2/3 complex.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Arp3 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Arp3 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Arp3 Arp66B
Source for merge of: Arp66B schwachling
FlyBase Curator comment: 'Arp66B' renamed to 'Arp3' to rationalize the nomenclature of Actin-related protein (Arp) genes (by orthology with the mammalian and yeast genes) and better reflect community usage.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
The Arp2/3 complex (including Arp66B) is required for actin cap expansion and pseudocleavage furrow formation during syncytial blastoderm divisions.