Gene model includes transcripts encoding non-overlapping portions of the full CDS.
Gene model reviewed during 5.48
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Skeletor using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Skeletor in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Skeletor CG14681
Annotations CG33676 and CG14681 (which were previously annotated as two non-overlapping open reading frames of a dicistronic transcript) merged as a single annotation (CG43161) in release 5.33 of the genome annotation.
Dicistronic annotation CG32922 split out into separate annotations for each open reading frame, CG14681 and CG33676, in release 4.2 of the genome annotation.
The locus encoding Skeletor is a complex locus that produces two mRNAs by alternative splicing (6.5kb and 1.6 kb). The larger of the mRNAs may have bicistronic coding potential. The 5' region of the first open reading frame "ORF1" is included in both the larger and smaller transcripts; in the shorter transcript this "ORF1a" conceptually translates to give a 32kD protein, and a 32kD protein has been detected by Western blot analysis, while in the longer transcript an "ORF1b" which conceptually translates to give an 85kD protein is predicted (however a protein of this predicted size has not been detected by Western blot analysis). The second open reading frame in the longer transcript ("ORF2") contains the sequence originally identified by the mAb2A Skeletor antibody and is predicted to produce a 81kD protein (a product of this size is detected by Western blot analysis).
Identification: in an expression library screen using monoclonal antibody 2A (mAb2A).
Skeletor encodes a novel nuclear matrix protein, identified using monoclonal antibody 2A (mAb2A).