Helix-turn-helix transcription factor - coactivator that translocates from the cytoplasm into the nucleus to induce stress-response genes - protects Enhancer of zeste mRNA from Pacman activity thereby ensuring Polycomb silencing - AP-1-dependent epithelial closure becomes sensitive to H2O2 in flies lacking MBF1 - co-activator for Tracheae Defective contributing to the formation of tracheal and nervous systems
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\mbf1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\mbf1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of mbf1 results in dorsal overextension of primary dendrites, defects in dendrite morphogenesis and a reduction in lateral branching.