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Gene Dmel\Rpb12

General Information
Symbol	Dmel\Rpb12	Species	D. melanogaster
Name	Rpb12	Annotation symbol	CG34186
Feature type	protein_coding_gene	FlyBase ID	FBgn0262954
Gene Model Status	Current	Stock availability	None publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	51E2-51E2	Sequence location	2R:11,032,473..11,033,024 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Rpb12 is referred to in FlyBase by the symbol Dmel\Rpb12 (CG34186, FBgn0262954). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: DNA-directed RNA polymerase activity. It is reported to be involved in the biological process: transcription from RNA polymerase II promoter. No alleles are reported. It has one annotated transcript and one annotated polypeptide. Protein features are: RNA polymerase archaeal subunit P/eukaryotic subunit RPC10. Gene sequence location is 2R:11032473..11033024.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 51E2-51E2
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Rpb12 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Rpb12-RA FBtr0112379  NM_001103849   353   57
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Rpb12-PA   FBpp0111294   6.8   57   9.36     NP_001097319   ABV53802
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RNA polymerase archaeal subunit P/eukaryotic subunit RPC10 (IPR006591)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE013599 ABV53802   BT030181   EV590808
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q6IGE3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic/larval midgut   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    48 central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male    32 head, mated 20-day male    50 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering    29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female    75 ovary, mated 4-day female    45 testis, mated 4-day male    35 accessory gland, mated 4-day male    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (51) central nervous system, larvae L3  (48) central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male  (32) head, mated 20-day male  (50) salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering  (28) digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering  (29) carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female  (75) ovary, mated 4-day female  (45) testis, mated 4-day male  (35) accessory gland, mated 4-day male  (29) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    48 central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male    32 head, mated 20-day male    50 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering    29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female    75 ovary, mated 4-day female    45 testis, mated 4-day male    35 accessory gland, mated 4-day male    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    48 central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male    32 head, mated 20-day male    50 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering    29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female    75 ovary, mated 4-day female    45 testis, mated 4-day male    35 accessory gland, mated 4-day male    29 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    48 central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male    32 head, mated 20-day male    50 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering    29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female    75 ovary, mated 4-day female    45 testis, mated 4-day male    35 accessory gland, mated 4-day male    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (51) central nervous system, larvae L3  (48) central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male  32 head, mated 20-day male  (50) salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering  28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering  29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female  (75) ovary, mated 4-day female  (45) testis, mated 4-day male  (35) accessory gland, mated 4-day male  29 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    48 central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male    32 head, mated 20-day male    50 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering    29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female    75 ovary, mated 4-day female    45 testis, mated 4-day male    35 accessory gland, mated 4-day male    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    51 central nervous system, larvae L3    48 central nervous system, pupae P8    25 head, virgin 1-day female    23 head, virgin 4-day female    20 head, virgin 20-day female    20 head, mated 1-day female    15 head, mated 4-day female    21 head, mated 20-day female    23 head, mated 1-day male    19 head, mated 4-day male    32 head, mated 20-day male    50 salivary gland, larvae L3 wandering    9 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    21 digestive system, 4-day adult    24 digestive system, 20-day adult    14 fat body, larvae L3 wandering    8 fat body, white prepupae    25 fat body, pupae P8    17 carcass, larvae L3 wandering    29 carcass, 1-day adult    14 carcass, 4-day adult    25 carcass, 20-day adult    22 ovary, virgin 4-day female    75 ovary, mated 4-day female    45 testis, mated 4-day male    35 accessory gland, mated 4-day male    29 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    34 embryo 02-04hr    58 embryo 04-06hr    89 embryo 06-08hr    44 embryo 08-10hr    55 embryo 10-12hr    53 embryo 12-14hr    55 embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr    27 larva L1    31 larva L2    37 larva L3 12hr old    27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    36 white prepupae new    39 white prepupae 12hr    38 white prepupae 24hr    45 pupae 2d postWPP    37 pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day    45 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (34) embryo 02-04hr  (58) embryo 04-06hr  (89) embryo 06-08hr  (44) embryo 08-10hr  (55) embryo 10-12hr  (53) embryo 12-14hr  (55) embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr  (27) larva L1  (31) larva L2  (37) larva L3 12hr old  (27) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9  (36) white prepupae new  (39) white prepupae 12hr  (38) white prepupae 24hr  (45) pupae 2d postWPP  (37) pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day  (45) adult female 30day  (38) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    34 embryo 02-04hr    58 embryo 04-06hr    89 embryo 06-08hr    44 embryo 08-10hr    55 embryo 10-12hr    53 embryo 12-14hr    55 embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr    27 larva L1    31 larva L2    37 larva L3 12hr old    27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    36 white prepupae new    39 white prepupae 12hr    38 white prepupae 24hr    45 pupae 2d postWPP    37 pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day    45 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    34 embryo 02-04hr    58 embryo 04-06hr    89 embryo 06-08hr    44 embryo 08-10hr    55 embryo 10-12hr    53 embryo 12-14hr    55 embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr    27 larva L1    31 larva L2    37 larva L3 12hr old    27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    36 white prepupae new    39 white prepupae 12hr    38 white prepupae 24hr    45 pupae 2d postWPP    37 pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day    45 adult female 30day    38 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    34 embryo 02-04hr    58 embryo 04-06hr    89 embryo 06-08hr    44 embryo 08-10hr    55 embryo 10-12hr    53 embryo 12-14hr    55 embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr    27 larva L1    31 larva L2    37 larva L3 12hr old    27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    36 white prepupae new    39 white prepupae 12hr    38 white prepupae 24hr    45 pupae 2d postWPP    37 pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day    45 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (34) embryo 02-04hr  (58) embryo 04-06hr  (89) embryo 06-08hr  (44) embryo 08-10hr  (55) embryo 10-12hr  (53) embryo 12-14hr  (55) embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr  27 larva L1  31 larva L2  (37) larva L3 12hr old  27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9  (36) white prepupae new  (39) white prepupae 12hr  (38) white prepupae 24hr  (45) pupae 2d postWPP  (37) pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day  (45) adult female 30day  (38) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    34 embryo 02-04hr    58 embryo 04-06hr    89 embryo 06-08hr    44 embryo 08-10hr    55 embryo 10-12hr    53 embryo 12-14hr    55 embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr    27 larva L1    31 larva L2    37 larva L3 12hr old    27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    36 white prepupae new    39 white prepupae 12hr    38 white prepupae 24hr    45 pupae 2d postWPP    37 pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day    45 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    34 embryo 02-04hr    58 embryo 04-06hr    89 embryo 06-08hr    44 embryo 08-10hr    55 embryo 10-12hr    53 embryo 12-14hr    55 embryo 14-16hr    10 embryo 16-18hr    18 embryo 18-20hr    10 embryo 20-22hr    20 embryo 22-24hr    27 larva L1    31 larva L2    37 larva L3 12hr old    27 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    36 white prepupae new    39 white prepupae 12hr    38 white prepupae 24hr    45 pupae 2d postWPP    37 pupae 3d postWPP    21 pupae 4d postWPP    7 adult male 01day    19 adult male 05day    22 adult male 30day    14 adult female 01day    13 adult female 05day    45 adult female 30day    38 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    177 Schneider line 2 Sg4    94 embryonic 1182-4H    20 embryonic GM2    111 embryonic Kc167    235 embryonic S1    68 embryonic S3    97 leg disc CME L1    68 wing disc CME-W2    166 wing disc ML-DmD8    50 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    52 wing disc ML-DmD21    78 wing disc ML-DmD32    38 haltere disc ML-DmD17-c3    61 eye-antennal disc ML-DmD11    33 antennal disc ML-DmD20-c5    58 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    89 CNS ML-DmBG2-c2    178 tumorous blood cells mbn2    130 ovary fGS/OSS    27 ovary OSC    81 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (177) Schneider line 2 Sg4  (94) embryonic 1182-4H    20 embryonic GM2  (111) embryonic Kc167  (235) embryonic S1  (68) embryonic S3  (97) leg disc CME L1  (68) wing disc CME-W2  (166) wing disc ML-DmD8  (50) wing disc ML-DmD9  (31) wing disc ML-DmD16-c3  (52) wing disc ML-DmD21  (78) wing disc ML-DmD32  (38) haltere disc ML-DmD17-c3  (61) eye-antennal disc ML-DmD11  (33) antennal disc ML-DmD20-c5  (58) mixed discs ML-DmD4-c1  (46) CNS ML-DmBG1-c1  (89) CNS ML-DmBG2-c2  (178) tumorous blood cells mbn2  (130) ovary fGS/OSS  (27) ovary OSC  (81) ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (177) Schneider line 2 Sg4    94 embryonic 1182-4H    20 embryonic GM2  (111) embryonic Kc167  (235) embryonic S1    68 embryonic S3    97 leg disc CME L1    68 wing disc CME-W2  (166) wing disc ML-DmD8    50 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    52 wing disc ML-DmD21    78 wing disc ML-DmD32    38 haltere disc ML-DmD17-c3    61 eye-antennal disc ML-DmD11    33 antennal disc ML-DmD20-c5    58 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    89 CNS ML-DmBG2-c2  (178) tumorous blood cells mbn2  (130) ovary fGS/OSS    27 ovary OSC    81 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    177 Schneider line 2 Sg4    94 embryonic 1182-4H    20 embryonic GM2    111 embryonic Kc167    235 embryonic S1    68 embryonic S3    97 leg disc CME L1    68 wing disc CME-W2    166 wing disc ML-DmD8    50 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    52 wing disc ML-DmD21    78 wing disc ML-DmD32    38 haltere disc ML-DmD17-c3    61 eye-antennal disc ML-DmD11    33 antennal disc ML-DmD20-c5    58 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    89 CNS ML-DmBG2-c2    178 tumorous blood cells mbn2    130 ovary fGS/OSS    27 ovary OSC    81 ovary OSS    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    177 Schneider line 2 Sg4    94 embryonic 1182-4H    20 embryonic GM2    111 embryonic Kc167    235 embryonic S1    68 embryonic S3    97 leg disc CME L1    68 wing disc CME-W2    166 wing disc ML-DmD8    50 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    52 wing disc ML-DmD21    78 wing disc ML-DmD32    38 haltere disc ML-DmD17-c3    61 eye-antennal disc ML-DmD11    33 antennal disc ML-DmD20-c5    58 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    89 CNS ML-DmBG2-c2    178 tumorous blood cells mbn2    130 ovary fGS/OSS    27 ovary OSC    81 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (177) Schneider line 2 Sg4  (94) embryonic 1182-4H    20 embryonic GM2  (111) embryonic Kc167  (235) embryonic S1  (68) embryonic S3  (97) leg disc CME L1  (68) wing disc CME-W2  (166) wing disc ML-DmD8  (50) wing disc ML-DmD9  31 wing disc ML-DmD16-c3  (52) wing disc ML-DmD21  (78) wing disc ML-DmD32  (38) haltere disc ML-DmD17-c3  (61) eye-antennal disc ML-DmD11  (33) antennal disc ML-DmD20-c5  (58) mixed discs ML-DmD4-c1  (46) CNS ML-DmBG1-c1  (89) CNS ML-DmBG2-c2  (178) tumorous blood cells mbn2  (130) ovary fGS/OSS  27 ovary OSC  (81) ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (177) Schneider line 2 Sg4    94 embryonic 1182-4H    20 embryonic GM2  111 embryonic Kc167  (235) embryonic S1    68 embryonic S3    97 leg disc CME L1    68 wing disc CME-W2  (166) wing disc ML-DmD8    50 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    52 wing disc ML-DmD21    78 wing disc ML-DmD32    38 haltere disc ML-DmD17-c3    61 eye-antennal disc ML-DmD11    33 antennal disc ML-DmD20-c5    58 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    89 CNS ML-DmBG2-c2  (178) tumorous blood cells mbn2  130 ovary fGS/OSS    27 ovary OSC    81 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    177 Schneider line 2 Sg4    94 embryonic 1182-4H    20 embryonic GM2    111 embryonic Kc167    235 embryonic S1    68 embryonic S3    97 leg disc CME L1    68 wing disc CME-W2    166 wing disc ML-DmD8    50 wing disc ML-DmD9    31 wing disc ML-DmD16-c3    52 wing disc ML-DmD21    78 wing disc ML-DmD32    38 haltere disc ML-DmD17-c3    61 eye-antennal disc ML-DmD11    33 antennal disc ML-DmD20-c5    58 mixed discs ML-DmD4-c1    46 CNS ML-DmBG1-c1    89 CNS ML-DmBG2-c2    178 tumorous blood cells mbn2    130 ovary fGS/OSS    27 ovary OSC    81 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    55 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    46 Rotenone 2 μg 12 hrs, larvae L3    49 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult  (29) Cadmium 50 mM 6 hrs, larvae L3  (34) Cadmium 50 mM 12 hrs, larvae L3  (55) Cadmium 50 mM 48 hrs, 4-day adult  (32) Cadmium 100 mM 48 hrs, 4-day adult  (48) Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult  (48) Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult  (30) Ethanol 2.5% 3 hrs, larvae L3  (34) Ethanol 5% 3 hrs, larvae L3  (39) Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (31) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (60) Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult  (47) Paraquat 10 mM 48 hrs, 4-day adult  (46) Rotenone 2 μg 12 hrs, larvae L3  (49) Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    55 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    46 Rotenone 2 μg 12 hrs, larvae L3    49 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    55 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    46 Rotenone 2 μg 12 hrs, larvae L3    49 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    55 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    46 Rotenone 2 μg 12 hrs, larvae L3    49 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult  29 Cadmium 50 mM 6 hrs, larvae L3  (34) Cadmium 50 mM 12 hrs, larvae L3  (55) Cadmium 50 mM 48 hrs, 4-day adult  32 Cadmium 100 mM 48 hrs, 4-day adult  (48) Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult  (48) Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult  30 Ethanol 2.5% 3 hrs, larvae L3  (34) Ethanol 5% 3 hrs, larvae L3  (39) Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3  31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (60) Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult  (47) Paraquat 10 mM 48 hrs, 4-day adult  (46) Rotenone 2 μg 12 hrs, larvae L3  (49) Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    55 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    46 Rotenone 2 μg 12 hrs, larvae L3    49 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    29 Cadmium 50 mM 6 hrs, larvae L3    34 Cadmium 50 mM 12 hrs, larvae L3    55 Cadmium 50 mM 48 hrs, 4-day adult    32 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    48 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    30 Ethanol 2.5% 3 hrs, larvae L3    34 Ethanol 5% 3 hrs, larvae L3    39 Ethanol 10% 3 hrs, larvae L3    18 Caffeine 1.5 mg/ml 4 hrs, larvae L3    31 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    60 Caffeine 25 mg/ml 48 hrs, 4-day adult    18 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    46 Rotenone 2 μg 12 hrs, larvae L3    49 Rotenone 8 μg 12 hrs, larvae L3    22 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_05 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	BDGP expression data • IP17848
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of Rpb12 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 0 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Rpb12 Class Mutagen Stocks Known lesion
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR006591 (FlyBase Curators et al., 2004-) DNA-directed RNA polymerase activity inferred from electronic annotation with InterPro:IPR006591 (FlyBase Curators et al., 2004-) non-traceable author statement (Aoyagi and Wassarman, 2000)
Biological Process
CV term Evidence References
transcription, DNA-dependent inferred from electronic annotation with InterPro:IPR006591 (FlyBase Curators et al., 2004-) transcription from RNA polymerase II promoter non-traceable author statement (Aoyagi and Wassarman, 2000)
Cellular Component
CV term Evidence References
DNA-directed RNA polymerase II, core complex non-traceable author statement (Aoyagi and Wassarman, 2000)
Sequence Ontology: Class of Gene
	gene   protein_coding_gene (FlyBase Genome Annotators, 2007)
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Rpb12 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0262954
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6SBFJT Dipteran inclusive ortholog search EOG6HQDV4 Insect inclusive ortholog search EOG6GTJB8 Arthropod inclusive ortholog search EOG6WPZKX Metazoa inclusive ortholog search EOG68Q0GF
Orthologs in Drosophila Species (EOG6SBFJT)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Rpb12     Drosophila simulans   Dsim\GD25636     Drosophila sechellia   Dsec\GM20158     Drosophila erecta   Dere\GG22374     Drosophila yakuba   Dyak\GE12262     Drosophila pseudoobscura pseudoobscura   Dpse\GA24334     Drosophila persimilis   Dper\GL17021     Drosophila willistoni   Dwil\GK19446     Drosophila willistoni   Dwil\GK19442     Drosophila virilis   Dvir\GJ20617     Drosophila mojavensis   Dmoj\GI20882     Drosophila grimshawi   Dgri\GH20797
Orthologs in non-Drosophila Dipterans (EOG6HQDV4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL017317   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL013457   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ002930
Orthologs in non-Dipteran Insects (EOG6GTJB8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB40252   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG027618   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21559   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH21560   Atta cephalotes Leafcutter ant  Acep\ACEP15341   Camponotus floridanus Florida carpenter ant  Cflo\CFLO12161   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL11607   Linepithema humile Argentine ant  Lhum\LH24110   Acyrthosiphon pisum Pea aphid  Apim\ACYPI061598   Pediculus humanus Human body louse  Phum\PHUM290480   Tribolium castaneum Red flour beetle  Tcas\TC005856
Orthologs in non-Insect Arthropods (EOG6WPZKX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\LFY   Ixodes scapularis Deer tick  Isca\ISCW023350
Orthologs in non-Arthropod Metazoa (EOG68Q0GF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\rpb-12   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008896gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_017323gn   Danio rerio Zebrafish  Drer\zgc:171795   Xenopus tropicalis Western clawed frog  Xtro\polr2k   Gallus gallus Domestic chicken  Ggal\POLR2K   Gallus gallus Domestic chicken  Ggal\POLR2K   Mus musculus House mouse  Mmus\Polr2k   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000010408   Homo sapiens Human  Hsap\POLR2K
Human Orthologs (1)
Gene OMIM HGNC Hsap\POLR2K
AAA Orthologs (0) based on analysis using Dmel annotation version 4.3
No orthologs identified
Stocks & Reagents
Stocks Listed in FlyBase ( 0 )
Genomic Clones ( 1 )
	BACR30C07 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 2 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	IP17848
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	Dmel_neb_015136_0388_2286
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740790
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Rpb12 CG34186 (FlyBase, 1992-)
Additional comments
Other Comments
	New annotation (CG34186) in release 5.2 of the genome annotation. (FlyBase Genome Annotators, 2007)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_001103849 RefSeq (Proteins) • NP_001097319 DDBJ / EMBL / GenBank • ABV53802 Entrez Gene - A searchable database of RefSeq genes. • 5740790 UniProtKB/TrEMBL • Q6IGE3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RNA polymerase archaeal subunit P/eukaryotic subunit RPC10 (IPR006591) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • IP17848
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0262954 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 5740790
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG34186 (FlyBase Genome Annotators, 2007, ) RPB12 (Aoyagi and Wassarman, 2000) Rpb12
Name Synonym	Rpb12
Secondary FlyBase IDs
	FBgn0043066 FBgn0085215
References ( 7 )
Research paper	Aoyagi and Wassarman, 2000, J. Cell Biol. 150(2): F45--F49 Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation. [FBrf0129705]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979]
Personal communication to FlyBase	FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Genome Annotators, 2007, Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 5.2 of the annotated D.melanogaster genome. [FBrf0199252] FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]