FlyBase Gene Report: Dmel\Chpf

General Information

Symbol

Dmel\Chpf

Species

D. melanogaster

Name

Chondroitin polymerizing factor

Annotation Symbol

CG43313

Feature Type

protein_coding_gene

FlyBase ID

FBgn0263005

Gene Model Status

Current

Stock Availability

10 publicly available

Enzyme Name (EC)

glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase (2.4.1.175)

N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase (2.4.1.226)

Gene Summary

Chondroitin polymerizing factor (Chpf) encodes an enzyme that catalyzes the transfer of glucuronic acid (GlcA) to a N-acetylgalactosamine (GalNAc) acceptor and of GalNAc to a GlcA acceptor. It is involved in the alternating addition of GlcA and GalNAc during the elongation of the chondroitin sulfate glycosaminoglycan chain. It may also act as an activating factor for Chsy during chondroitin chain polymerization. [Date last reviewed: 2024-12-19] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Key Links

Genomic Location

Cytogenetic map

11D10-11D11

Sequence location

X:13,095,571..13,112,462 [-]

Recombination map

1-41

RefSeq locus

NC_004354 REGION:13095571..13112462

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables acetylgalactosaminyltransferase activity

inferred from electronic annotation with InterPro:IPR008428

(InterPro Project Members, 2004-)

enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN000961885

(GO Reference Genome Project, 2011-)

inferred from sequence or structural similarity with UniProtKB:Q8IZ52

(Gene Ontology Curators, 2002-)

enables N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

inferred from sequence or structural similarity with UniProtKB:Q8IZ52

(Gene Ontology Curators, 2002-)

Biological Process (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

involved_in chondroitin sulfate biosynthetic process

inferred from biological aspect of ancestor with PANTHER:PTN000961885

(GO Reference Genome Project, 2011-)

involved_in chondroitin sulfate proteoglycan biosynthetic process, chain elongation

inferred from sequence or structural similarity with UniProtKB:Q8IZ52

(Gene Ontology Curators, 2002-)

Cellular Component (2 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in Golgi apparatus

inferred from sequence or structural similarity with UniProtKB:Q6IQX7

(Gene Ontology Curators, 2002-)

located_in Golgi cisterna membrane

inferred from electronic annotation with InterPro:IPR008428

(InterPro Project Members, 2004-)

Gene Group (FlyBase)

CHONDROITIN SYNTHASES

GLUCURONOSYLTRANSFERASES

Pathway (FlyBase)

CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity

(1) 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta- D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D- Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+) (2.4.1.226)

(2) 3-O-{[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)](n)-beta-D-GalNAc- (1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D- Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{beta-D-GlcA- (1->3)-[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)](n)-beta-D-GalNAc-(1->4)- beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L- seryl-[protein] + UDP + H(+) (2.4.1.226)

glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

(1) 3-O-(beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta- D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N- acetyl-alpha-D-galactosamine = 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA- (1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D- Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+) (2.4.1.175)

(2) 3-O-{beta-D-GlcA-(1->3)-[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)](n)- beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal- (1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-{[beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)](n+1)-beta-D-GalNAc- (1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D- Xyl}-L-seryl-[protein] + UDP + H(+) (2.4.1.175)

Summaries

Gene Snapshot

Gene Group (FlyBase)

CHONDROITIN SYNTHASES -: Chondroitin synthases possess a galactosaminyltransferase activity that contributes to the elongation of chondroitin, a glycosaminoglycan that plays a key role in tissue development and morphogenesis. (Adapted from PMID: 21468578.)
GLUCURONOSYLTRANSFERASES -: Glucuronosyltransferases catalyze the conjugation of glucuronic acid from UDP-glucuronate to an acceptor, typically a small lipophilic molecule. (Adapted from PMID:26453144.)

Pathway (FlyBase)

CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS -: Chondroitin sulfate proteoglycans (CSPGs) are glycoconjugates that consist of a core protein linked to one or more linear chondroitin sulfate (CS) chains. The chains are composed of alternating glucuronic acid and N-acetylgalactosamine that can be variably O-sulfated. CS synthesis occurs in the Golgi apparatus. It starts with the formation of a tetrasaccharide linker on the core protein followed by the alternating addition of glucuronic acid and N-acetylgalactosamine residues, the latter of which can be O-sulfated. CSPGs are then transported to the plasma membrane. D. melanogaster produces two types of CSPGs: one bearing 4-O-sulfated chondroitin and another with non-sulfated chondroitin. (Adapted from PMID:23774590 and FBrf0228609.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Chpf for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VYH2)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.50

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.56

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Chpf-RA

FBtr0306847

NM_132625

3781

819

Chpf-RB

FBtr0346130

NM_001298255

4326

819

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Chpf-PA

FBpp0297743

93.4

819

7.94

FBpp0311959

93.4

819

7.94

Q9VYH2

NP_001285184

AHN59654

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

819 aa isoforms: Chpf-PA, Chpf-PB

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Chpf using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG43313_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.59

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Chpf in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Chpf

View exonic expression by tissue for Dmel\Chpf

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

32259/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0263005

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0263005

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG4351

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 10 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Chpf

Transgenic constructs containing regulatory region of Chpf

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene partially disrupted in

Df(1)CRIMIC-CR70826

(Gene Disruption Project members, 2018-)

Inferred from location ( 21 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^Act5C.PU

Chpf^RNAi.UAS.cYa

lethal | recessive

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

viable, with Scer\GAL4^tin.CΔ4

Chpf^GD11291

Sterility

Allele

fertile

Other Phenotypes

Allele

abnormal pain response | adult stage, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Chpf^GD11291

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (15)

Hsap\CHPF

14 of 14

Yes

Hsap\CHPF2

13 of 14

Yes

Hsap\B4GALNT3

2 of 14

Yes

Hsap\B4GALNT4

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (16)

Rnor\Chpf

14 of 14

Yes

Rnor\Chpf2

13 of 14

Yes

Rnor\B4galnt3

2 of 14

Yes

Rnor\B4galnt4

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (17)

Mmus\Chpf2

13 of 14

Yes

Mmus\Chpf

13 of 14

Yes

Mmus\B4galnt3

2 of 14

Yes

Mmus\B4galnt4

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (10)

Xtro\chpf

7 of 13

Yes

Xtro\chpf2

6 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\vav1

1 of 13

Danio rerio (Zebrafish) (21)

Drer\chpfa

14 of 14

Yes

Drer\chpf2

13 of 14

Yes

Drer\chpfb

13 of 14

Yes

Drer\b4galnt3a

2 of 14

Yes

Drer\b4galnt3b

2 of 14

Yes

Drer\b4galnt4a

2 of 14

Yes

Drer\b4galnt4b

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Drer\si:dkey-202e17.1

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (13)

Cele\mig-22

13 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (6)

Agam\AgaP_AGAP001050

12 of 12

Yes

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (0)

Saccharomyces cerevisiae (Brewer's yeast) (0)

Schizosaccharomyces pombe (Fission yeast) (0)

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Chpf. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (15)

3 of 13

3 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

fng

1 of 13

tgy

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

CHPF; chondroitin polymerizing factor

14 of 14

610405

CHPF2; chondroitin polymerizing factor 2

13 of 14

608037

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Other Interaction Browsers

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0263005

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

CHONDROITIN SULFATE PROTEOGLYCAN BIOSYNTHESIS

External Links

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

chondroitin biosynthesis

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

Chondroitin sulfate biosynthesis

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Chondroitin sulfate biosynthesis

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-41

Cytogenetic map

11D10-11D11

Sequence location

X:13,095,571..13,112,462 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

11D10-11D11

Limits computationally determined from genome sequence between P{EP}EP1461 and P{EP}CG1640^EP1626

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

1-41

(FlyBase, 2016)

1-41.5

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (10)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

53990

y¹ v¹; P{TRiP.HMJ21394}attP40

37882

y¹ w^* Mi{MIC}Chpf^MI04955

603612

y¹ w¹; P{TKO-UAS.GS06284}attP40/CyO

16537

y¹ w^67c23 P{EPgy2}Chpf^EY00553

77755

y¹ w^* Mi{Trojan-GAL4.0}Chpf^{MI04955-TG4.0}

Kyoto

125749

w¹¹¹⁸ P{RS5}Chpf^5-HA-2930

NIG-Fly

HMJ21394

y¹ v¹; P{TRiP.HMJ21394}attP40/CyO

HMJ22218

y¹ v¹; P{TRiP.HMJ22218}attP40/CyO

VDRC

v106610

P{KK106286}VIE-260B

v26519

w¹¹¹⁸; P{GD11291}v26519

Genomic Clones (12)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (15)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0263005

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Relationship to Other Genes

Source for database merge of

Source for merge of: CG4351 CG12714

(FlyBase Genome Annotators, 2011)

Additional comments

Annotations CG4351 and CG12714 merged as CG43313 in release 5.35 of the genome annotation.

(FlyBase Genome Annotators, 2011)

Nomenclature History

Source for database identify of

Source for identity of: Chpf CG43313

(Yamamoto-Hino et al., 2015)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG12714

(Keleman et al., 2009.8.5)

CG34413

(Gupta and Stocker, 2020)

CG43313

(Guichard et al., 2023, National Institute of Genetics Fly Stocks, 2023-, Gene Disruption Project members, 2016-, Yamamoto-Hino et al., 2015, FlyBase Genome Annotators, 2011, Ni et al., 2010.12.1)

CG4351

(Ashwal-Fluss et al., 2014)

Chpf

(Huang et al., 2023, Transgenic RNAi Project members, 2017-)

dCHPF

(Yamamoto-Hino et al., 2015)

Name Synonyms

Chondroitin polymerizing factor

Secondary FlyBase IDs

FBgn0030448
FBgn0040862

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 43 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

32259

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VYH2

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VYH2

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

32259/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0263005

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0263005

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG43313

MARRVEL_MODEL - MARRVEL (model organism gene)

32259

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0263005

DroID - A comprehensive database of gene and protein interactions.

FBgn0263005

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG43313_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0263005

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

chondroitin biosynthesis

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG4351

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0263005

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC033453

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Chondroitin sulfate biosynthesis

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

Chondroitin sulfate biosynthesis

References (35)

The following external sites may use different assemblies or annotations than FlyBase.

-0.59

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