• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\BtbVII

General Information
Symbol	Dmel\BtbVII	Species	D. melanogaster
Name	BTB-protein-VII	Annotation symbol	CG43365
Feature type	protein_coding_gene	FlyBase ID	FBgn0263108
Gene Model Status	Current	Stock availability	6 publicly available
Also Known As	BTB-VII, CG11494
Genomic Location
Chromosome (arm)	3L	Recombination map	3-
Cytogenetic map	63B7-63B7	Sequence location	3L:3,148,646..3,158,408 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene BTB-protein-VII is referred to in FlyBase by the symbol Dmel\BtbVII (CG43365, FBgn0263108). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: DNA binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; DNA binding HTH domain, Psq-type; Homeodomain-like. Gene sequence location is 3L:3148646..3158408.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 63B7-63B7   Limits computationally determined from genome sequence between P{PZ}l(3)0680306803 and P{PZ}kst01318
Experimentally Determined Cytological Location
Cytogenetic map Notes References 63B-63C     (Laski, 1994.9.5)
Experimentally Determined Recombination Data
Location	3- (Laski, 1994.9.5)
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\BtbVII for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.44 Gene model reviewed during 5.45 Stop-codon suppression (UAG) postulated; FBrf0216884. gene_with_stop_codon_read_through ; SO:0000697 Low-frequency RNA-seq exon junction(s) not annotated. Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters. Annotated transcripts do not represent all supported alternative splices within 5' UTR. Gene merge based on RNA-Seq junction data.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) BtbVII-RA FBtr0307301  NM_001259661   3321   743 BtbVII-RB FBtr0307302  NM_079172   3907   743 BtbVII-RD FBtr0307304  NM_001259662   4752   743 BtbVII-RE FBtr0307305  NM_167990   4017   743 BtbVII-RF FBtr0307306  NM_139517   3943   907 BtbVII-RG FBtr0330148  NM_001144408   3321   816 BtbVII-RH FBtr0330149  NM_001274426   3336   748 BtbVII-RI FBtr0332096  NM_001274427   4043   747
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein BtbVII-PA   FBpp0298302   78.4   743   7.14     NP_001246590   AFH04261 BtbVII-PB   FBpp0298303   78.4   743   7.14     NP_523896   AAN11533 BtbVII-PD   FBpp0298305   78.4   743   7.14     NP_001246591   AFH04262 BtbVII-PE   FBpp0298306   78.4   743   7.14     NP_728814   AAF47721 BtbVII-PF   FBpp0298307   95.7   907   7.58     NP_647774   AAF47722 BtbVII-PG   FBpp0303181   85.7   816   7.01     NP_001137880   ACL83236 BtbVII-PH   FBpp0303182   79.0   748   7.00     NP_001261355   AGB94050 BtbVII-PI   FBpp0304406   78.9   747   7.23     NP_001261356   AGB94051
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) DNA binding HTH domain, Psq-type (IPR007889) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333) Homeodomain-like (IPR009057)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA202410   AA202943   AA441623   AA816602   AE014296 AAF47721   AE014296 AAF47722   AE014296 AAN11533   AE014296 ACL83236   AE014296 AFH04261   AE014296 AFH04262   AE014296 AGB94050   AE014296 AGB94051   AI108545   AI109993   AI388741   AI389342   AI405851   AI512520   AI518744   AI520228   AW940268   AW941521   AW943424   AY051895 AAK93319   AY094684 AAM11037   BF494638   BF496925   BI214329   BI237962   BI239744   BI242381   BI361321   BI485887   BI636149   BI639549   BP549907   CK658180   CK659293   CK660381   CL525959   CO185758   CO188684   CO263601   CO263888   CO268490   CO269706   CO282861   CO287671   CO299047   CO299271   CO306235   CO307870   CO312355   CO323168   CO327657   CO332100   CO343614   CZ467073   DN154173   EC051746   EC057808   EC074772   EC075079   EC195222   EC197348   EC208245   EC209712   EC213580   EC218790   EC219921   EC220831   EC228994   EC234078   EC237445   EC241932   EC241953   EC246598   EC251093   EC256192   EC256573   EL876184   EV575700   EV590526   EV595372   EV599295   FL502762   GH740485   GH741885   GH744440   GH745176   GH745466   GH745764   GH747426   GH762387   GH763459   GH764437   GH767113   GH768177   GH769656   U14404 AAA50839
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q960S0 Q9VZU5 Q9VZU6 Q8SXC5 B7Z045
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic brain   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval nervous system   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    28 central nervous system, larvae L3    48 central nervous system, pupae P8    32 head, virgin 1-day female    23 head, virgin 4-day female    27 head, virgin 20-day female    18 head, mated 1-day female    26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male    33 head, mated 4-day male    40 head, mated 20-day male    40 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female    56 ovary, mated 4-day female    61 testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (28) central nervous system, larvae L3  (48) central nervous system, pupae P8  (32) head, virgin 1-day female    23 head, virgin 4-day female  (27) head, virgin 20-day female    18 head, mated 1-day female  26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male  (33) head, mated 4-day male  (40) head, mated 20-day male  (40) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8  (30) carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female  (56) ovary, mated 4-day female  (61) testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    28 central nervous system, larvae L3    48 central nervous system, pupae P8    32 head, virgin 1-day female    23 head, virgin 4-day female    27 head, virgin 20-day female    18 head, mated 1-day female    26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male    33 head, mated 4-day male    40 head, mated 20-day male    40 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female    56 ovary, mated 4-day female    61 testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    28 central nervous system, larvae L3    48 central nervous system, pupae P8    32 head, virgin 1-day female    23 head, virgin 4-day female    27 head, virgin 20-day female    18 head, mated 1-day female    26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male    33 head, mated 4-day male    40 head, mated 20-day male    40 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female    56 ovary, mated 4-day female    61 testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    28 central nervous system, larvae L3    48 central nervous system, pupae P8    32 head, virgin 1-day female    23 head, virgin 4-day female    27 head, virgin 20-day female    18 head, mated 1-day female    26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male    33 head, mated 4-day male    40 head, mated 20-day male    40 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female    56 ovary, mated 4-day female    61 testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  28 central nervous system, larvae L3  (48) central nervous system, pupae P8  32 head, virgin 1-day female    23 head, virgin 4-day female  27 head, virgin 20-day female    18 head, mated 1-day female  26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male  (33) head, mated 4-day male  (40) head, mated 20-day male  (40) salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8  30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female  (56) ovary, mated 4-day female  (61) testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    28 central nervous system, larvae L3    48 central nervous system, pupae P8    32 head, virgin 1-day female    23 head, virgin 4-day female    27 head, virgin 20-day female    18 head, mated 1-day female    26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male    33 head, mated 4-day male    40 head, mated 20-day male    40 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female    56 ovary, mated 4-day female    61 testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    28 central nervous system, larvae L3    48 central nervous system, pupae P8    32 head, virgin 1-day female    23 head, virgin 4-day female    27 head, virgin 20-day female    18 head, mated 1-day female    26 head, mated 4-day female    23 head, mated 20-day female    17 head, mated 1-day male    33 head, mated 4-day male    40 head, mated 20-day male    40 salivary gland, larvae L3 wandering    3 salivary gland, white prepupae    14 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    8 digestive system, 4-day adult    13 digestive system, 20-day adult    13 fat body, larvae L3 wandering    11 fat body, white prepupae    23 fat body, pupae P8    30 carcass, larvae L3 wandering    22 carcass, 1-day adult    15 carcass, 4-day adult    16 carcass, 20-day adult    16 ovary, virgin 4-day female    56 ovary, mated 4-day female    61 testis, mated 4-day male    17 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    78 embryo 02-04hr    39 embryo 04-06hr    27 embryo 06-08hr    31 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr    27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day    33 adult female 05day    44 adult female 30day    49 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (78) embryo 02-04hr  (39) embryo 04-06hr  (27) embryo 06-08hr  (31) embryo 08-10hr  (28) embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr  (27) embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day  (33) adult female 05day  (44) adult female 30day  (49) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    78 embryo 02-04hr    39 embryo 04-06hr    27 embryo 06-08hr    31 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr    27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day    33 adult female 05day    44 adult female 30day    49 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    78 embryo 02-04hr    39 embryo 04-06hr    27 embryo 06-08hr    31 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr    27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day    33 adult female 05day    44 adult female 30day    49 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    78 embryo 02-04hr    39 embryo 04-06hr    27 embryo 06-08hr    31 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr    27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day    33 adult female 05day    44 adult female 30day    49 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (78) embryo 02-04hr  (39) embryo 04-06hr  27 embryo 06-08hr  31 embryo 08-10hr  28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr  27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day  (33) adult female 05day  (44) adult female 30day  (49) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    78 embryo 02-04hr    39 embryo 04-06hr    27 embryo 06-08hr    31 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr    27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day    33 adult female 05day    44 adult female 30day    49 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    78 embryo 02-04hr    39 embryo 04-06hr    27 embryo 06-08hr    31 embryo 08-10hr    28 embryo 10-12hr    23 embryo 12-14hr    18 embryo 14-16hr    20 embryo 16-18hr    20 embryo 18-20hr    27 embryo 20-22hr    22 embryo 22-24hr    20 larva L1    15 larva L2    9 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    15 larva L3 puffstage 7-9    17 white prepupae new    18 white prepupae 12hr    20 white prepupae 24hr    22 pupae 2d postWPP    18 pupae 3d postWPP    13 pupae 4d postWPP    19 adult male 01day    17 adult male 05day    22 adult male 30day    23 adult female 01day    33 adult female 05day    44 adult female 30day    49 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    18 embryonic 1182-4H    26 embryonic GM2    20 embryonic Kc167    31 embryonic S1    31 embryonic S3    28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    22 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    44 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    31 tumorous blood cells mbn2    35 ovary fGS/OSS    33 ovary OSC    62 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (69) Schneider line 2 Sg4    18 embryonic 1182-4H  26 embryonic GM2    20 embryonic Kc167  (31) embryonic S1  (31) embryonic S3  (28) leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9  (39) wing disc ML-DmD16-c3  (33) wing disc ML-DmD21    22 wing disc ML-DmD32  (30) haltere disc ML-DmD17-c3  (44) eye-antennal disc ML-DmD11  (27) antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1  (33) CNS ML-DmBG1-c1  (33) CNS ML-DmBG2-c2  (31) tumorous blood cells mbn2  (35) ovary fGS/OSS  (33) ovary OSC  (62) ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    18 embryonic 1182-4H    26 embryonic GM2    20 embryonic Kc167    31 embryonic S1    31 embryonic S3    28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    22 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    44 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    31 tumorous blood cells mbn2    35 ovary fGS/OSS    33 ovary OSC    62 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    18 embryonic 1182-4H    26 embryonic GM2    20 embryonic Kc167    31 embryonic S1    31 embryonic S3    28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    22 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    44 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    31 tumorous blood cells mbn2    35 ovary fGS/OSS    33 ovary OSC    62 ovary OSS    21 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    18 embryonic 1182-4H    26 embryonic GM2    20 embryonic Kc167    31 embryonic S1    31 embryonic S3    28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    22 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    44 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    31 tumorous blood cells mbn2    35 ovary fGS/OSS    33 ovary OSC    62 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (69) Schneider line 2 Sg4    18 embryonic 1182-4H  26 embryonic GM2    20 embryonic Kc167  31 embryonic S1  31 embryonic S3  28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9  (39) wing disc ML-DmD16-c3  (33) wing disc ML-DmD21    22 wing disc ML-DmD32  30 haltere disc ML-DmD17-c3  (44) eye-antennal disc ML-DmD11  27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1  (33) CNS ML-DmBG1-c1  (33) CNS ML-DmBG2-c2  31 tumorous blood cells mbn2  (35) ovary fGS/OSS  (33) ovary OSC  (62) ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    18 embryonic 1182-4H    26 embryonic GM2    20 embryonic Kc167    31 embryonic S1    31 embryonic S3    28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    22 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    44 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    31 tumorous blood cells mbn2    35 ovary fGS/OSS    33 ovary OSC    62 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    18 embryonic 1182-4H    26 embryonic GM2    20 embryonic Kc167    31 embryonic S1    31 embryonic S3    28 leg disc CME L1    23 wing disc CME-W2    17 wing disc ML-DmD8    25 wing disc ML-DmD9    39 wing disc ML-DmD16-c3    33 wing disc ML-DmD21    22 wing disc ML-DmD32    30 haltere disc ML-DmD17-c3    44 eye-antennal disc ML-DmD11    27 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    33 CNS ML-DmBG1-c1    33 CNS ML-DmBG2-c2    31 tumorous blood cells mbn2    35 ovary fGS/OSS    33 ovary OSC    62 ovary OSS    21 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    38 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (30) cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult  (48) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult  (30) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3  (53) Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (43) Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult  (40) Paraquat 10 mM 48 hrs, 4-day adult  (38) Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    38 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    38 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    38 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult  (48) Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult  30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3  (53) Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (43) Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult  (40) Paraquat 10 mM 48 hrs, 4-day adult  (38) Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    38 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    30 cold shock, 4-day adult    23 heat shock, 4-day adult    25 Cadmium 50 mM 6 hrs, larvae L3    7 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    22 Cadmium 100 mM 48 hrs, 4-day adult    48 Copper 0.5 mM 12 hrs, larvae L3    9 Copper 15 mM 48 hrs, 4-day adult    30 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    22 Ethanol 2.5% 3 hrs, larvae L3    53 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    6 Caffeine 1.5 mg/ml 4 hrs, larvae L3    8 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    43 Caffeine 25 mg/ml 48 hrs, 4-day adult    25 Paraquat 5 mM 48 hrs, 4-day adult    40 Paraquat 10 mM 48 hrs, 4-day adult    38 Rotenone 2 μg 12 hrs, larvae L3    5 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
External Data & Images
Linkouts	BDGP expression data • LD38452
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 BtbVIIGD1701 viable BtbVIIEY07802 Sterility Allele fertile BtbVIIEY07802 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 BtbVIIGD1701 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 BtbVIIGD1701 mesothoracic tergum, with Scer\GAL4pnr-MD237 BtbVIIGD1701
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of BtbVII Class Mutagen Stocks Known lesion BtbVII5-SZ-3514 1 -- BtbVIIEY07802 P-element activity 1 -- BtbVIIc01320 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 5 )
For All Alleles Carried on Transgenic Constructs Show
Allele of BtbVII Class Mutagen Stocks Known lesion BtbVIIGD1701 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes BtbVIIHM05123 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes BtbVIIKK103826 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes BtbVIIGD16511 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes BtbVIIJF02203 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD16511} NA P{KK103826} NA P{TRiP.HM05123} NA P{TRiP.JF02203} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}BtbVIIEY07802 NA miscellaneous insertions P{RS5}BtbVII5-SZ-3514 NA PBac{PB}BtbVIIc01320 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR011526 (FlyBase Curators et al., 2004-) non-traceable author statement (Lehmann, 2002.7.1)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) gene_with_stop_codon_read_through (Jungreis et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
BtbVII - CG10077 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) BtbVII - CG7518 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) BtbVII - Hsp70Aa anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) BtbVII - Pp2A-29B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) BtbVII - lolal anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions BtbVII allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0263108
Orthologs
OrthoDB Orthologs (20) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6HMJW6 Dipteran inclusive ortholog search EOG64TPHF Insect inclusive ortholog search EOG6XWDTZ Arthropod inclusive ortholog search EOG6B2RD9 Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6HMJW6)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\BtbVII     Drosophila simulans   Dsim\GD13729 Y   Drosophila sechellia   Dsec\GM14536 Y   Drosophila yakuba   Dyak\GE20361 Y   Drosophila ananassae   Dana\GF24269 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13381 Y   Drosophila virilis   Dvir\GJ13140 Y   Drosophila mojavensis   Dmoj\GI12996 Y
Orthologs in non-Drosophila Dipterans (EOG64TPHF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010845   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL012371   Anopheles gambiae Malaria mosquito  Agam\AGAP006453   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017152
Orthologs in non-Dipteran Insects (EOG6XWDTZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Atta cephalotes Leafcutter ant  Acep\ACEP18342   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15199   Linepithema humile Argentine ant  Lhum\LH12503   Pogonomyrmex barbatus Red harvester ant  Pbar\PB21379   Solenopsis invicta Red fire ant  Sinv\SINV18043   Tribolium castaneum Red flour beetle  Tcas\TC003617
Orthologs in non-Insect Arthropods (EOG6B2RD9)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW016667   Ixodes scapularis Deer tick  Isca\ISCW007900
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (18) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD13728 Drosophila simulans Dsim\GD13729 Drosophila sechellia Dsec\GM14532 Drosophila sechellia Dsec\GM14536 Drosophila erecta Dere\GG14906 Drosophila erecta Dere\GG14907 Drosophila yakuba Dyak\GE20360 Drosophila yakuba Dyak\GE20361 Drosophila ananassae Dana\GF24269 Drosophila ananassae Dana\GF24270 Drosophila pseudoobscura pseudoobscura Dpse\GA11032 Drosophila pseudoobscura pseudoobscura Dpse\GA13381 Drosophila virilis Dvir\GJ13138 Drosophila virilis Dvir\GJ13140 Drosophila mojavensis Dmoj\GI12995 Drosophila mojavensis Dmoj\GI12996 Drosophila grimshawi Dgri\GH15390 Drosophila grimshawi Dgri\GH15391
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	28912 y1 v1; P{TRiP.HM05123}attP2 17405 y1 w67c23; P{EPgy2}BtbVIIEY07802
Kyoto	126109 w1118; P{RS5}BtbVII5-SZ-3514
VDRC	v106063 P{KK103826}VIE-260B v3254 w1118; P{GD1701}v3254 v3255 w1118; P{GD1701}v3255
Genomic Clones ( 1 )
	BACR48E19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 85 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH07729 LD38452
Other clones	DPiM_LD38452
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03340 AT10936 GH09415 GH19736 GH20484 GH25994 LD02582 LD02602 LD16619 LD40321 LD44417 LP14907 LP16955 LP18915 RE20106 RE34306 RE36325 RE39686 RE45484 RE69240 SD17729 SD22159
Other clones	10940 29094 45477 64276 65850 71702 101666 118074 214435.17 214469.13 274900 CK01.8C.B8 CK01.41B.C3 CK01.49B.G2 CK01.77D.C7 CK01.82D.D6 CK01.83B.E6 CK01.106C.B6 CK01.120A.C4 CK01.129A.G9 Dmel_dig_008575_0641_2464 Dmel_neb_003789_0641_2747 Dmel_neb_004823_0933_3528 Dmel_neb_014721_0313_3281 DMG4-chr3L.6.007.pred.a EC051746 EK011640 EK041457 EK066451 EK089039 EK091642 EK095620 EK136764 EK161460 EK174410 EK174951 EK189853 EK193259 EK228534 EK250601 EK255902 EK302520 EP07822 EP17356 FGM104B08 IP06025 LD03441 RP001011858 RP001013068 RP001019412 RP001021080 RP001024110 RP001028380 RP001030021 RP001043339 RP001044333 RP001045527 RP001046314 RP001047608 RP001051799
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38376
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: BtbVII CG11494 (Gabrielian, 1999.11)
Source for database merge of	Source for merge of: BtbVII CG14956 (FlyBase Genome Annotators, 2011) Source for merge of: CG14956 BcDNA:GH07729 (FlyBase, 1996-)
Additional comments	Annotations CG11494 and CG14956 merged as CG43365 in release 5.36 of the genome annotation. (FlyBase Genome Annotators, 2011) Source for merge of CG14956 BcDNA:GH07729 was a shared cDNA (date:020730). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079172 NM_139517 NM_167990 NM_001144408 NM_001259661 NM_001259662 NM_001274426 NM_001274427 RefSeq (Proteins) • NP_523896 NP_647774 NP_728814 NP_001137880 NP_001246590 NP_001246591 NP_001261355 NP_001261356 DDBJ / EMBL / GenBank • AA202943 AAA50839 AAF47721 AAF47722 AAK93319 AAM11037 AAN11533 ACL83236 AFH04261 AFH04262 AGB94050 AGB94051 AI108545 AI518744 AW940268 AW941521 AW943424 AY051895 AY094684 CL525959 CZ467073 U14404 Entrez Gene - A searchable database of RefSeq genes. • 38376 38377 UniProtKB/TrEMBL • B7Z045 Q8SXC5 Q9VZU5 Q9VZU6 Q960S0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) DNA binding HTH domain, Psq-type (IPR007889) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333) Homeodomain-like (IPR009057) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD38452
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0263108 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 38376
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	BcDNA:GH07729   BtbVII (Jungreis et al., 2011, Kwong et al., 2008) BTB-VII (Laski, 1994.9.5, Zollman et al., 1994) CG11494 (Keleman et al., 2009.8.5, Perkins et al., 2009) CG14956 (Ferjoux et al., 2007) CG43365 (FlyBase Genome Annotators, 2011)
Name Synonym	BTB protein VII (Siegmund and Lehmann, 2002) BTB-protein-VII
Secondary FlyBase IDs
	FBgn0012049 FBgn0035403 FBgn0062503
References ( 29 )
Generate a list of	All references relating to this gene ( 29 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 5 ) Personal communication to FlyBase  ( 9 ) FlyBase analysis  ( 4 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 3 ) Website  ( 1 )
Recent research papers ( 1 )
	Quan et al., 2011, Nat. Biotechnol. 29(5): 449--452 Parallel on-chip gene synthesis and application to optimization of protein expression. [FBrf0213642] Show all research papers ...