Gene Dmel\BtbVII

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General Information

Symbol

Dmel\BtbVII

Species

D. melanogaster

Name

BTB-protein-VII

Annotation symbol

CG43365

Feature type

protein_coding_gene

FlyBase ID

FBgn0263108

Gene Model Status

Current

Stock availability

6 publicly available

Also Known As

BTB-VII, CG11494

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

63B7-63B7

Sequence location

3L:3,148,650..3,158,408 [+]

Genomic Maps

Select View:

modENCODE GBrowse

Summary Information

Automatically generated summary

See sections below for more information

The gene BTB-protein-VII is referred to in FlyBase by the symbol Dmel\BtbVII (CG43365, FBgn0263108). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: DNA binding. The biological processes in which it is involved are not known. 8 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Helix-turn-helix, Psq; Helix-turn-helix, Psq-like; Homeodomain-like. Gene sequence location is 3L:3148650..3158408.

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2012_01

Sequence features

HFA08415

BKN29704

HFA08151

BKN24018

FB2011_10

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

63B7-63B7

Limits computationally determined from genome sequence between P{PZ}l(3)06803⁰⁶⁸⁰³ and P{PZ}kst⁰¹³¹⁸

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

63B-63C

(Laski, 1994.9.5)

Experimentally Determined Recombination Data

Location

(Laski, 1994.9.5)

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\BtbVII for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene merge based on RNA-Seq junction data.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

BtbVII-RA

FBtr0307301

3317

743

BtbVII-RB

FBtr0307302

3907

743

BtbVII-RC

FBtr0307303

3263

798

BtbVII-RD

FBtr0307304

4752

743

BtbVII-RE

FBtr0307305

4017

743

BtbVII-RF

FBtr0307306

3939

907

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

BtbVII-PA

FBpp0298302

78.4

743

7.14

BtbVII-PB

FBpp0298303

78.4

743

7.14

BtbVII-PC

FBpp0298304

83.8

798

7.01

BtbVII-PD

FBpp0298305

78.4

743

7.14

BtbVII-PE

FBpp0298306

78.4

743

7.14

BtbVII-PF

FBpp0298307

95.7

907

7.58

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

BTB/POZ-like (IPR000210)

Helix-turn-helix, Psq (IPR007889)

Helix-turn-helix, Psq-like (IPR011526)

BTB/POZ (IPR013069)

BTB/POZ fold (IPR011333)

Homeodomain-like (IPR009057)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Notes

High-Throughput Expression Data

Untitled Document detailed view

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

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modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

Expression Clusters

External Data & Images

Linkouts

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

semi-lethal | pupal stage, with Scer\GAL4^pnr-MD237

BtbVII^GD1701

viable

BtbVII^EY07802

Sterility

Allele

fertile

BtbVII^EY07802

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

BtbVII^GD1701

Phenotype manifest in

Allele

chaeta | supernumerary, with Scer\GAL4^pnr-MD237

BtbVII^GD1701

mesothoracic tergum, with Scer\GAL4^pnr-MD237

BtbVII^GD1701

Classical Alleles ( 3 )

For All Classical Alleles Show

Allele of BtbVII	Mutagen	Stocks	Known lesion
BtbVII^5-SZ-3514		1	--
BtbVII^EY07802	P-element activity	1	--
BtbVII^c01320	piggyBac transposase	0	--

Alleles Carried on Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Allele of BtbVII	Mutagen	Stocks	Known lesion
BtbVII^GD1701	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
BtbVII^HM05123	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
BtbVII^KK103826	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
BtbVII^GD16511	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes
BtbVII^JF02203	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EPgy2}BtbVII^EY07802

miscellaneous insertions

P{RS5}BtbVII^5-SZ-3514

PBac{PB}BtbVII^c01320

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function

CV term

Evidence

References

DNA binding

inferred from electronic annotation with InterPro:IPR007889, InterPro:IPR011526

(FlyBase Curators et al., 2004-)

non-traceable author statement

(Lehmann, 2002.7.1)

Biological Process ( 0 terms)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Protein-protein

Interacting group

Assay

References

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

BtbVII allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0263108

Orthologs

Genome-wide drosophilid orthologs

Dana\GF24269

Dana\GF24270

Dere\GG14906

Dere\GG14907

Dgri\GH15390

Dgri\GH15391

Dmoj\GI12995

Dmoj\GI12996

Dpse\GA11032

Dpse\GA13381

Dsec\GM14532

Dsec\GM14536

Dsim\GD13728

Dsim\GD13729

Dvir\GJ13138

Dvir\GJ13140

Dyak\GE20360

Dyak\GE20361

Curated drosophilid orthologs

Dpse\GA11032

Dpse\GA13381

Linkouts

Stocks & Reagents

Stocks Listed in FlyBase ( 6 )

Bloomington

28912

y¹ v¹; P{TRiP.HM05123}attP2

17405

y¹ w^67c23; P{EPgy2}BtbVII^EY07802

Kyoto

126109

w¹¹¹⁸; P{RS5}BtbVII^5-SZ-3514

VDRC

v106063

P{KK103826}VIE-260B

v3254

w¹¹¹⁸; P{GD1701}v3254

v3255

w¹¹¹⁸; P{GD1701}v3255

Genomic Clones ( 1 )

BACR48E19

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 85 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

DPiM_LD38452

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for identity of: BtbVII CG11494

(Gabrielian, 1999.11)

Source for database merge of

Source for merge of: BtbVII CG14956

(FlyBase Genome Annotators, 2011)

Source for merge of: CG14956 BcDNA:GH07729

(FlyBase, 1996-)

Additional comments

Annotations CG11494 and CG14956 merged as CG43365 in release 5.36 of the genome annotation.

(FlyBase Genome Annotators, 2011)

Source for merge of CG14956 BcDNA:GH07729 was a shared cDNA (date:020730).

(FlyBase, 1996-)

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

BTB/POZ-like (IPR000210)

Helix-turn-helix, Psq (IPR007889)

Helix-turn-helix, Psq-like (IPR011526)

BTB/POZ (IPR013069)

BTB/POZ fold (IPR011333)

Homeodomain-like (IPR009057)

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0263108

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

Synonyms & Secondary IDs ( 8 )

Reported As

Symbol Synonym

BcDNA:GH07729

BTB-VII

(Laski, 1994.9.5, Zollman et al., 1994)

BtbVII

(Kwong et al., 2008)

CG11494

(Keleman et al., 2009.8.5, Perkins et al., 2009)

CG14956

CG43365

(FlyBase Genome Annotators, 2011)

Name Synonym

BTB protein VII

(Siegmund and Lehmann, 2002)

BTB-protein-VII

Secondary FlyBase IDs

FBgn0012049
FBgn0035403
FBgn0062503

References ( 24 )

Generate a list of

All references relating to this gene ( 24 )

List References by type

Recent research papers ( 1 )

Quan et al., 2011, Nat. Biotechnol. 29(5): 449--452: Parallel on-chip gene synthesis and application to optimization of protein expression. [FBrf0213642]

Show all research papers ...