5HT1B, d5-HT1B, 5HT-dro2B, 5-HT1B, 5-HT1BDro
Stop-codon suppression (UGA) postulated; FBrf0216884
Gene model reviewed during 5.44
Gene model reviewed during 5.50
4.9 (northern blot)
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\5-HT1B using the Feature Mapper tool.
5-HT1B transcripts are detected throughout development with a peak in 16-24hr embryos. They are found in adult heads but not bodies. In embryos, expression starts in stage 16 and is restricted to the CNS. 5-HT1B transcripts are expressed in lateral rows of cells on each side of the midline and at a low level in midline cells.
GBrowse - Visual display of RNA-Seq signalsView Dmel\5-HT1B in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: 5-HT1B CG30126
Annotation CG30126 merged with annotation CG15113 in release 5.36 of the genome annotation; CG30126 corresponds to 5' UTR of CG15113.
New annotation (CG30126) in release 3 of the genome annotation.
5-HT1B receptor inhibits adenylate cyclase and activates phospholipase C. Expression starts in late embryos and is restricted to distinct populations in the CNS. 5-HT1A and 5-HT1B have a common chromosomal location and high sequence homology suggesting they are the result of a recent duplication event.
One of several known Drosophila serotonin receptor encoding genes. Presumed to be a recent duplication of 5-HT1A gene.