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Gene Dmel\tx

General Information
Symbol	Dmel\tx	Species	D. melanogaster
Name	taxi	Annotation symbol	CG5441
Feature type	protein_coding_gene	FlyBase ID	FBgn0263118
Gene Model Status	Current	Stock availability	21 publicly available
Also Known As	dei, del, Delilah
Genomic Location
Chromosome (arm)	3R	Recombination map	3-91
Cytogenetic map	97B2-97F9	Sequence location	3R:22,266,500..22,274,713 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene taxi is referred to in FlyBase by the symbol Dmel\tx (CG5441, FBgn0263118). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: bHLH transcription factor binding; protein heterodimerization activity; E-box binding. There is experimental evidence that it is involved in the biological process: imaginal disc-derived wing vein specification; cell adhesion mediated by integrin; muscle attachment; mesoderm development. 15 alleles are reported. The phenotypes of these alleles are annotated with: wing sensillum; wing. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Myc-type, basic helix-loop-helix (bHLH) domain. Gene sequence location is 3R:22266500..22274713.
User Contributed Data
	Beta version, feedback welcome
Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	tx: taxi (J.C. Hall) tx: taxi From Collins, 1928, Am. Naturalist 62: 127-36. Wings held out at about 75 from body axis, often arched or wavy, somewhat narrow and dusky. Unable to fly because of shape and posture of wings. RK2.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 97B2-97F9   Limits computationally determined from genome sequence between P{PZ}l(3)rQ197rQ197 and P{lacW}scribj7B3; Left limit from recombination mapping relative to asp (FBrf0049898) Right limit from recombination mapping relative to l(3)mbt (FBrf0058988)
Experimentally Determined Cytological Location
Cytogenetic map Notes References 97B-97B     (Armand, 1994.5.31) 97B-97B   (determined by in situ hybridisation)   (Armand et al., 1994)
Experimentally Determined Recombination Data
Location	3-91
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\tx for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) tx-RA FBtr0085009  NM_079792   1993   384 tx-RB FBtr0339598     2411   384
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein tx-PA   FBpp0084381   41.5   384   6.19     NP_524516   AAF56590 tx-PB   FBpp0308670   41.5   384   6.19
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Myc-type, basic helix-loop-helix (bHLH) domain (IPR011598)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140686   AA203106   AE014297 AAF56590   AI403531   AW940884   AY051581 AAK93005   BF500854   BI357135   BI357586   BI362003   BT003640 AAO39644   CO188043   CO307259   CO318491   CO324709   CZ479293   EC078283   EC078284   EC195231   EC199570   EC203585   EC216377   EC246344   EL874694   GH748304   GH780597   GH784291   GH810128   GH811821   GH909997   GH912499   GH930174   GH930839   L33401 AAA28449
UniProtKB/Swiss-Prot	P41894
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   longitudinal visceral muscle primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium visceral muscle primordium   (Fisher et al., 2012) Comment:reported as muscle system primordium embryonic stage 12 -- 17   tendon cell   (Armand et al., 1994) embryonic stage 13 -- 16   embryonic dorsal apodeme   (Fisher et al., 2012) embryonic ventral apodeme   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) embryonic/larval somatic muscle   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012) embryonic stage 16 -- 17   tendon cell of pharyngeal muscle   (Armand et al., 1994) Comment:Reference states 14-18 hr AEL
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    1 central nervous system, pupae P8    2 head, virgin 1-day female    4 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    4 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    8 head, mated 20-day male    6 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    2 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    5 carcass, 1-day adult    5 carcass, 4-day adult    9 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr    28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr  (28) embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr    28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr    28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr    28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr  28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr    28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    2 embryo 08-10hr    6 embryo 10-12hr    15 embryo 12-14hr    15 embryo 14-16hr    22 embryo 16-18hr    28 embryo 18-20hr    23 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    3 larva L3 12hr old    5 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    3 larva L3 puffstage 7-9    2 white prepupae new    3 white prepupae 12hr    2 white prepupae 24hr    5 pupae 2d postWPP    9 pupae 3d postWPP    22 pupae 4d postWPP    9 adult male 01day    4 adult male 05day    4 adult male 30day    5 adult female 01day    2 adult female 05day    1 adult female 30day    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2    42 wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2  (42) wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2    42 wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2    42 wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2    42 wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2  (42) wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2    42 wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    6 embryonic 1182-4H    17 embryonic GM2    7 embryonic Kc167    12 embryonic S1    20 embryonic S3    0 leg disc CME L1    10 wing disc CME-W2    42 wing disc ML-DmD8    0 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    1 eye-antennal disc ML-DmD11    18 antennal disc ML-DmD20-c5    9 mixed discs ML-DmD4-c1    0 CNS ML-DmBG1-c1    0 CNS ML-DmBG2-c2    1 tumorous blood cells mbn2    1 ovary fGS/OSS    4 ovary OSC    13 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    2 heat shock, 4-day adult    5 Cadmium 50 mM 6 hrs, larvae L3    5 Cadmium 50 mM 12 hrs, larvae L3    3 Cadmium 50 mM 48 hrs, 4-day adult    6 Cadmium 100 mM 48 hrs, 4-day adult    5 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    6 Ethanol 2.5% 3 hrs, larvae L3    5 Ethanol 5% 3 hrs, larvae L3    5 Ethanol 10% 3 hrs, larvae L3    5 Caffeine 1.5 mg/ml 4 hrs, larvae L3    6 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    2 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    5 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_29 mE1_20_mRNA_expression_cluster_11
External Data & Images
Linkouts	BDGP expression data • GH22991
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die, with Scer\GAL4how-24B txGD4329 viable tx1 tx52j txe01478 viable, with Scer\GAL4pnr-MD237 txGD4329 Sterility Allele fertile txe01478 Other Phenotypes Allele hypoactive | third instar larval stage txe01478 uncoordinated | third instar larval stage txe01478 visible tx1 tx33-2 tx52j txe01478 txMB03174 visible, with Scer\GAL4en-e16E txGD4329 visible, with Scer\GAL4how-24B txGD4329 visible, with Scer\GAL4pnr-MD237 txGD4329 visible (with Df(3R)ED6232) tx3 tx8 tx14 visible (with tx1) tx14 visible (with tx14) tx1 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 txGD4329 trichogen cell | supernumerary, with Scer\GAL4pnr-MD237 txGD4329 wing txe01478 tx1 tx33-2 wing, with Scer\GAL4en-e16E txGD4329 wing, with Scer\GAL4how-24B txGD4329 wing sensillum tx1 wing sensillum (with Df(3R)ED6232) tx14 wing sensillum (with tx1) tx14 wing sensillum (with tx14) tx1 wing vein | ectopic txMB03174 wing vein | ectopic (with Df(3R)ED6232) tx3 tx8 tx14
Classical Alleles ( 9 )
For All Classical Alleles Show
Allele of tx Class Mutagen Stocks Known lesion tx1 hypomorphic allele - genetic evidence spontaneous 10 Yes txe01478 piggyBac transposase 2 Yes txMB03174 1 Yes txMI03096 1 -- tx14 ethyl methanesulfonate 0 Yes tx33-2 transposable element activity 0 Yes tx3 ethyl methanesulfonate 0 Yes tx52j 0 -- tx8 ethyl methanesulfonate 0 Yes
Alleles Carried on Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Allele of tx Class Mutagen Stocks Known lesion txGD4329 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes txScer\UAS.cMa in vitro construct - regulatory fusion 2 Yes txHMS00101 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes txJF01995 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes txKK105148 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes txScer\UAS.T:Hsim\VP16 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Espl3 (Cook and Carpenter, 2002) Df(3R)ME61 (Cook and Carpenter, 2002) Df(3R)Tl-I (Cook and Carpenter, 2002) Df(3R)Tl-P (Cook and Carpenter, 2002) Df(3R)Tl-X (Cook and Carpenter, 2002) T(2;3)ClassIII (Howe et al., 1995) T(2;3)lt-x13p20 (Howe et al., 1995) T(2;3)lt-x13p89 (Howe et al., 1995) T(2;3)tx-p1 (Howe et al., 1995) T(2;3)tx-p5 (Howe et al., 1995) T(2;3)tx-p15 (Howe et al., 1995) T(2;3)tx-p17 (Howe et al., 1995) T(2;3)tx-p18 (Howe et al., 1995) T(2;3)tx-p19 (Howe et al., 1995) T(2;3)tx-p31 (Howe et al., 1995) T(2;3)tx-x13p100 (Howe et al., 1995)
Not disrupted in	Df(3R)ro80b (Cook and Carpenter, 2002)
Partially disrupted in	Df(3R)tx33-2 (Egoz-Matia et al., 2011)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.HMS00101} NA P{UAS-dei.M} NA P{UAS-VP16-dei} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{?ET1}tx33-2 NA Mi{MIC}txMI03096 NA PBac{RB}txe01478 NA insertion of enhancer trap binary system Mi{ET1}txMB03174 No
Gene Ontology: Function, Process & Cellular Component ( 12 unique terms )
Terms Based on Experimental Evidence ( 7 terms )
Molecular Function
CV term Evidence References
bHLH transcription factor binding inferred from direct assay (Armand et al., 1994) contributes_to E-box binding inferred from direct assay (Armand et al., 1994) protein heterodimerization activity inferred from direct assay (Armand et al., 1994)
Biological Process
CV term Evidence References
cell adhesion mediated by integrin inferred from mutant phenotype (Egoz-Matia et al., 2011) imaginal disc-derived wing vein specification inferred from mutant phenotype (Egoz-Matia et al., 2011) mesoderm development inferred from expression pattern (Furlong et al., 2001) muscle attachment inferred from expression pattern (Armand et al., 1994)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
sequence-specific DNA binding RNA polymerase II transcription factor activity inferred by curator from GO:0070888|GO:0043425 (Armand et al., 1994) inferred from sequence or structural similarity with da (Armand et al., 1994) sequence-specific DNA binding transcription factor activity inferred from sequence or structural similarity with UniProtKB:Q15784 (FlyBase, 1992-) non-traceable author statement (Swiss-Prot Project Members, 1995.6.1)
Biological Process
CV term Evidence References
muscle attachment traceable author statement (Furlong et al., 2001) regulation of transcription, DNA-dependent inferred from sequence or structural similarity with da (Armand et al., 1994) somatic muscle development traceable author statement (Furlong et al., 2001)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity with UniProtKB:Q15784 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	gene   nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions tx allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0263118
Orthologs
OrthoDB Orthologs (20) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6RXZKJ Dipteran inclusive ortholog search EOG6J6S10 Insect inclusive ortholog search EOG63JB1X Arthropod inclusive ortholog search EOG63FFD1 Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6RXZKJ)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\tx     Drosophila simulans   Dsim\GD21279 Y   Drosophila sechellia   Dsec\GM10319 Y   Drosophila erecta   Dere\GG11475 Y   Drosophila yakuba   Dyak\GE23667 Y   Drosophila ananassae   Dana\GF20734 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA18883 Y   Drosophila persimilis   Dper\GL21846 Y   Drosophila willistoni   Dwil\GK13968 Y   Drosophila virilis   Dvir\GJ23868 Y   Drosophila mojavensis   Dmoj\GI22620 Y   Drosophila grimshawi   Dgri\GH19416 Y
Orthologs in non-Drosophila Dipterans (EOG6J6S10)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL007779   Anopheles gambiae Malaria mosquito  Agam\AGAP003876   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009017
Orthologs in non-Dipteran Insects (EOG63JB1X)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Acyrthosiphon pisum Pea aphid  Apim\ACYPI001969   Bombyx mori Silkmoth  Bmor\BGIBMGA008390   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07598   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07594
Orthologs in non-Insect Arthropods (EOG63FFD1)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW016573
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD21279 Drosophila sechellia Dsec\GM10319 Drosophila erecta Dere\GG11475 Drosophila yakuba Dyak\GE23667 Drosophila ananassae Dana\GF20734 Drosophila pseudoobscura pseudoobscura Dpse\GA18883 Drosophila persimilis Dper\GL21846 Drosophila willistoni Dwil\GK13968 Drosophila virilis Dvir\GJ23868 Drosophila mojavensis Dmoj\GI22620 Drosophila grimshawi Dgri\GH19416
Stocks & Reagents
Stocks Listed in FlyBase ( 21 )
Bloomington	625 tx1 1376 hhbar3 tx1 36931 y1 w*; P{UAS-dei.M}H3 36932 y1 w*; P{UAS-dei.M}H2 17955 w1118; PBac{RB}txe01478 23839 w1118; Mi{ET1}txMB03174
Harvard	- PBac{RB}txe01478
Kyoto	106016 tx1 106293 hhbar3 tx1
VDRC	v102831 P{KK105148}VIE-260B v37629 w1118; P{GD4329}v37629 v37630 w1118; P{GD4329}v37630
	More stocks available...
Genomic Clones ( 2 )
	BACR15K06 BACR48G23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 27 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	AT16005 GH22991
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD03611 RE43523 RE44110 RE46452
Other clones	44599 61053 148606 167138 193569 CK01.43B.B12 CK00397 EK036540 EK194556 EK254225 EK272343 IP14809 RP003019106 RP003089319 RP003113184 RP003164937 RP003200890 RP003275248 RP003374482 RP003454100 RP003469479
RNAi & Array Information
Linkouts	GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43190
Antibody Information
	polyclonal (Egoz-Matia et al., 2011)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: tx dei (Egoz-Matia et al., 2011)
Additional comments
Other Comments
	ChEST reveals this is a target of Mef2. (Junion et al., 2005) dei is expressed in muscle attachment cells and expression is temporally correlated with the positions of muscle attachment. dei expression is not induced by muscle attachment. (Armand et al., 1994) Phenotypic variation of the genetic components underlying oviposition behaviour is analysed using the complete diallel mating design. (Ruiz-Dubreuil and del Solar, 1993)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079792 RefSeq (Proteins) • NP_524516 DDBJ / EMBL / GenBank • AAA28449 AAF56590 AAK93005 AAO39644 AI403531 AW940884 AY051581 BF500854 BT003640 CZ479293 L33401 Entrez Gene - A searchable database of RefSeq genes. • 43190 UniProtKB/Swiss-Prot • P41894
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Myc-type, basic helix-loop-helix (bHLH) domain (IPR011598) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH22991
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0263118 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 43190
Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym	bHLHc10 (Stevens et al., 2008) CG5441 (Whitfield, 2001.1.5, Perkins et al., 1.15.2009, Keleman et al., 2009.8.5, Ni et al., 2011.7.19) dei (Egoz-Matia et al., 2011, Chanana et al., 2007, Sandmann et al., 2006, Kwon et al., 2008, Zeitlinger et al., 2007, Michelson and Volk, 2011.11.28, Zhou et al., 2012) Dei (Klein et al., 2010) del (Hossain et al., 2005, Vorbruggen and Jackle, 1997) Delilah (Armand, 1994.5.31) delilah (Staudt et al., 2005) tx (Egoz-Matia et al., 2011, )
Name Synonym	delilah (Volk et al., 1997, Chanana et al., 2007, Staudt et al., 2005, Sandmann et al., 2006) Delilah (Michelson and Volk, 2011.11.28) taxi (Michelson and Volk, 2011.11.28) taxi wings (Egoz-Matia et al., 2011)
Secondary FlyBase IDs
	FBgn0003904 FBgn0008649
References ( 82 )
Generate a list of	All references relating to this gene ( 82 )
List References by type	Research paper  ( 46 ) Supplementary material  ( 6 ) Review  ( 5 ) Personal communication to FlyBase  ( 13 ) Abstract  ( 5 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Protein sequence record  ( 1 ) Website  ( 1 ) Book  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 3 )
	Halachmi et al., 2012, J. Vis. Exp.: Visualization of proprioceptors in Drosophila larvae and pupae. [FBrf0218666] Zhou et al., 2012, PLoS Genet. 8(3): e1002593 Phenotypic plasticity of the Drosophila transcriptome. [FBrf0217974] Egoz-Matia et al., 2011, Dev. Biol. 351(1): 99--109 Spatial regulation of cell adhesion in the Drosophila wing is mediated by Delilah, a potent activator of βPS integrin expression. [FBrf0213026] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...