FB2020_06, released Dec 22, 2020

Gene: Dmel\bin3

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General Information
Symbol
Dmel\bin3
Species
D. melanogaster
Name
bicoid-interacting protein 3
Annotation Symbol
CG8276
Feature Type
protein_coding_gene
FlyBase ID
FBgn0263144
Gene Model Status
Current
Stock Availability
30 publicly available
Gene Snapshot
bicoid-interacting protein 3 (bin3) encodes an RNA methyltransferase that adds a 5'-methyl cap to the product of snRNA:7SK preventing its degradation. It contributes to inhibition of cad mRNA translation in the anterior of the embryo. [Date last reviewed: 2019-05-16]
Other Summaries
Key Links
Genomic Location
Cytogenetic map
42A12-42A14
Sequence location
2R:6,214,568..6,240,602 [+]
Recombination map

2-55

RefSeq locus
NT_033778 REGION:6214568..6240602
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (12 terms)
Molecular Function (6 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
enables protein binding
inferred from physical interaction with UniProtKB:P09081
(assigned by UniProt )
(Zhu and Hanes, 2000)
enables RNA polymerase II transcription factor binding
inferred from physical interaction with FLYBASE:bcd; FB:FBgn0000166
(Zhu and Hanes, 2000)
enables snRNA binding
inferred from direct assay
(Singh et al., 2011)
Terms Based on Predictions or Assertions (4 terms)
CV Term
Evidence
References
enables methyltransferase activity
inferred from sequence or structural similarity with SGD:S000000238
(Zhu and Hanes, 2000)
enables O-methyltransferase activity
inferred from biological aspect of ancestor with PANTHER:PTN000267975
(assigned by GO_Central )
(Gaudet et al., 2011)
enables RNA methyltransferase activity
inferred from biological aspect of ancestor with PANTHER:PTN000267975
(assigned by GO_Central )
(Gaudet et al., 2011)
enables snRNA binding
inferred from biological aspect of ancestor with PANTHER:PTN000267972
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (5 terms)
Terms Based on Experimental Evidence (3 terms)
CV Term
Evidence
References
involved_in developmental process
inferred from mutant phenotype
(assigned by UniProt )
(Zhu and Hanes, 2000)
involved_in heterochromatin organization involved in chromatin silencing
inferred from mutant phenotype
(Swenson et al., 2016)
involved_in negative regulation of translation
inferred from mutant phenotype
(Singh et al., 2011)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in methylation
inferred from sequence or structural similarity with SGD:S000000238
(Zhu and Hanes, 2000)
involved_in snRNA modification
inferred from biological aspect of ancestor with PANTHER:PTN000267972
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Swenson et al., 2016)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Protein Family (UniProt)
Belongs to the methyltransferase superfamily. (Q7K480)
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
OTHER RNA METHYLTRANSFERASES -
The Other RNA methyltransferases is a collection of transferases that do not fit into any of the other major RNA methyltransferases.
7SK SMALL NUCLEAR RIBONUCLEOPROTEIN -
7SK small nuclear ribonucleoprotein (7SK snRNP) plays a central role in RNA polymerase II elongation control by sequestering positive transcription elongation factor complex b (P-TEFb) and therefore regulating the availability of active P-TEFb. (Adapted from PMID:28431135.)
Protein Function (UniProtKB)
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it (By similarity). Required for dorso-ventral patterning in oogenesis and for anterior-posterior pattern formation during embryogenesis, possibly by binding and stabilizing 7SK RNA, thereby promoting formation of a repressive RNA-protein complex (PubMed:21262214).
(UniProt, Q7K480)
Gene Model and Products
Number of Transcripts
4
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\bin3 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 6.02

Sequence Ontology: Class of Gene
gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
bin3-RA
FBtr0085993
NM_165468
5606
1367
bin3-RB
FBtr0085992
NM_078902
4760
1367
bin3-RC
FBtr0336519
NM_001273795
4718
1367
bin3-RD
FBtr0346718
NM_001316407
5616
1367
Additional Transcript Data and Comments
Reported size (kB)

4.588 (compiled cDNA)

(Zhu and Hanes, 2000)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
bin3-PA
FBpp0085337
146.2
1367
9.20
NP_724468
AAF57267
bin3-PB
FBpp0085336
146.2
1367
9.20
NP_523626
AAM68350
bin3-PC
FBpp0307591
146.2
1367
9.20
NP_001260724
AGB93258
bin3-PD
FBpp0312329
146.2
1367
9.20
NP_001303336
ALI30166
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1367 aa isoforms: bin3-PA, bin3-PB, bin3-PC, bin3-PD
Additional Polypeptide Data and Comments
Reported size (kDa)

1368 (aa); 146 (kD predicted)

(Zhu and Hanes, 2000)
Comments
External Data
Subunit Structure (UniProtKB)

Interacts with bicoid/bcd.

(UniProt, Q7K480)
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bin3 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 3
organism

Comment: maternally deposited

(Fisher et al., 2012)
embryonic stage 4 -- 6
organism | ubiquitous
(Fisher et al., 2012)
embryonic stage 7 -- 8
anterior endoderm anlage
(Fisher et al., 2012)
foregut anlage
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 9 -- 10
anterior endoderm
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior endoderm
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
embryonic stage 11 -- 12
amnioserosa
(Fisher et al., 2012)
central brain primordium
(Fisher et al., 2012)
foregut primordium
(Fisher et al., 2012)
head mesoderm
(Fisher et al., 2012)
hindgut proper primordium
(Fisher et al., 2012)
Malpighian tubule primordium
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
posterior midgut primordium
(Fisher et al., 2012)
trunk mesoderm
(Fisher et al., 2012)
ventral nerve cord primordium
(Fisher et al., 2012)
embryonic stage 13 -- 16
embryonic brain
(Fisher et al., 2012)
organism | faint | ubiquitous
(Fisher et al., 2012)
organism | ubiquitous
(Fisher et al., 2012)
ventral nerve cord
(Fisher et al., 2012)
northern blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 1 -- 9

Comment: reference states 0-4 hr AEL

(Zhu and Hanes, 2000)
organism | ubiquitous
(Zhu and Hanes, 2000)
Additional Descriptive Data

Northern blot analysis indicates that bin3 transcripts are most abundant in 0-2hr embryos, are at lower levels in 2-4hr embryos and drop dramatically in 4-24hr embryos. In situ hybridization shows that bin3 transcripts are distributed throughout the early embryo and in unfertilized eggs.

(Zhu and Hanes, 2000)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(Swenson et al., 2016)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\bin3 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 56 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of bin3
Transgenic constructs containing regulatory region of bin3
Deletions and Duplications ( 0 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal (with Df(2R)BSC313)
lethal | recessive
lethal - all die before end of embryonic stage | maternal effect, with Scer\GAL4VP16.mat.αTub67C
lethal - all die before end of embryonic stage | maternal effect (with bin32-7)
lethal - all die before end of embryonic stage | maternal effect (with bin34-7)
lethal - all die before end of embryonic stage | maternal effect (with Df(2R)Drlrv25)
viable
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Sterility
Allele
fertile
Other Phenotypes
Allele
sleep defective | adult stage
smell perception defective
some die during embryonic stage | maternal effect, with Scer\GAL4VP16.mat.αTub67C
some die during embryonic stage | maternal effect (with bin32-7)
some die during embryonic stage | maternal effect (with bin34-7)
some die during embryonic stage | maternal effect (with Df(2R)Drlrv25)
suppressor of variegation, with P{SUPor-P}KV00108
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
cephalopharyngeal skeleton (with bin32-7)
cephalopharyngeal skeleton (with bin34-7)
embryonic head | maternal effect, with Scer\GAL4VP16.mat.αTub67C
mesothoracic tergum, with Scer\GAL4pnr-MD237
ovariole
tormogen cell, with Scer\GAL4pnr-MD237
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\MEPCE
10 of 15
Yes
No
Hsap\BCDIN3D
2 of 15
No
No
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (2)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Mepce
9 of 15
Yes
No
Mmus\Bcdin3d
2 of 15
No
No
Rattus norvegicus (Norway rat) (3)
Rnor\LOC100910540
7 of 13
Yes
Yes
Rnor\Mepce
4 of 13
No
No
Rnor\Bcdin3d
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (2)
Xtro\mepce
2 of 12
Yes
Yes
Xtro\bcdin3d
1 of 12
No
No
Danio rerio (Zebrafish) (3)
Drer\mepce
9 of 15
Yes
Yes
Drer\si:ch1073-157b13.1
9 of 15
Yes
Yes
Drer\bcdin3d
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (1)
Cele\Y17G7B.18
8 of 15
Yes
No
Arabidopsis thaliana (thale-cress) (1)
Atha\AT5G51130
4 of 9
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\SPBC2A9.10
5 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091901T4 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00006522
Drosophila simulans
Dsim\GD10403
Drosophila sechellia
Dsec\GM16541
Drosophila erecta
Dere\GG23201
Drosophila yakuba
Dyak\GE20781
Drosophila ananassae
Dana\GF11051
Drosophila pseudoobscura pseudoobscura
Dpse\GA26118
Drosophila pseudoobscura pseudoobscura
Dpse\GA20948
Drosophila persimilis
Dper\GL20337
Drosophila willistoni
Dwil\GK19498
Drosophila virilis
Dvir\GJ21451
Drosophila mojavensis
Dmoj\GI18374
Drosophila grimshawi
Dgri\GH20938
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503NY )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17019869
Glossina morsitans
Tsetse fly
Gmor\GMOY010300
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09385
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_09391
Mayetiola destructor
Hessian fly
Mdes\Mdes011093
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL003540
Anopheles darlingi
American malaria mosquito
Adar\ADAC005797
Anopheles gambiae
Malaria mosquito
Agam\AGAP012087
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ006467
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ000796
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03GK )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA006788
Danaus plexippus
Monarch butterfly
Dple\DPOGS213805-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL014722
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )
No non-Arthropod Metazoa orthologies identified
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (2)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG1239
7 of 10
CG11342
4 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    MEPCE; methylphosphate capping enzyme
    10 of 15
    611478
        Functional Complementation Data
        Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
        Interactions
        Summary of Physical Interactions
        esyN Network Diagram
        Show neighbor-neighbor interactions:
        Select Layout:
        Legend:
        Protein
        RNA
        Selected Interactor(s)
        Interactions Browser
        View in Interactions Browser
        Please see the Physical Interaction reports below for full details
        protein-protein
        Physical Interaction
        Assay
        References
        bin3 - CG14074
        two hybrid
        (Hu et al., 2017.6.13)
        bin3 - CG2017
        two hybrid
        (Hu et al., 2017.6.13)
        bin3 - CG44250
        two hybrid
        (Hu et al., 2017.6.13)
        bin3 - CG7824
        two hybrid
        (Hu et al., 2017.6.13)
        bin3 - CG9467
        two hybrid
        (Hu et al., 2017.6.13)
        bin3 - Lim1
        two hybrid
        (Hu et al., 2017.6.13)
        bin3 - bcd
        pull down, autoradiography, two hybrid
        (Zhu and Hanes, 2000)
        RNA-protein
        Physical Interaction
        Assay
        References
        bin3 - snRNA:7SK
        anti tag coimmunoprecipitation, quantitative reverse transcription pcr
        (Singh et al., 2011)
        Summary of Genetic Interactions
        esyN Network Diagram
        esyN Network Key:
        Suppression
        Enhancement
        View in Interactions Browser
        Please look at the allele data for full details of the genetic interactions
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        bin3
        enhanceable
        bcd
        (Singh et al., 2011)
        Starting gene(s)
        Interaction type
        Interacting gene(s)
        Reference
        External Data
        Subunit Structure (UniProtKB)
        Interacts with bicoid/bcd.
        (UniProt, Q7K480 )
        Linkouts
        DroID - A comprehensive database of gene and protein interactions.
        MIST (protein-protein) - An integrated Molecular Interaction Database
        Pathways
        Signaling Pathways (FlyBase)
        Metabolic Pathways
        External Data
        Linkouts
        Genomic Location and Detailed Mapping Data
        Chromosome (arm)
        2R
        Recombination map

        2-55

        Cytogenetic map
        42A12-42A14
        Sequence location
        2R:6,214,568..6,240,602 [+]
        FlyBase Computed Cytological Location
        Cytogenetic map
        Evidence for location
        42A12-42A14
        Left limit from in situ hybridisation (FBrf0157097) Right limit from in situ hybridisation (FBrf0157097); Limits computationally determined from genome sequence between P{lacW}l(2)k09848k09848&P{EP}EP407 and P{lacW}geminink14019&P{PZ}Adf101349
        Experimentally Determined Cytological Location
        Cytogenetic map
        Notes
        References
        42A12-42A13
        (Oh et al., 2003)
        42A16-42B2
        (Zhu, 1998.10.6)
        42B-42B
        (determined by in situ hybridisation)
        (Zhu and Hanes, 2000)
        Experimentally Determined Recombination Data
        Location

        2-55

        (FlyBase, 2016)

        2-55.8

        (Comeron et al., 2012)
        Left of (cM)
        Right of (cM)
        Notes
        Stocks and Reagents
        Stocks (30)
        Genomic Clones (22)
        cDNA Clones (50)
         

        Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

        cDNA clones, fully sequenced
        BDGP DGC clones
        Other clones
          Drosophila Genomics Resource Center cDNA clones

          For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

          cDNA Clones, End Sequenced (ESTs)
          BDGP DGC clones
          Other clones
          RNAi and Array Information
          Linkouts
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          Antibody Information
          Laboratory Generated Antibodies
           

          polyclonal

          (Singh et al., 2011)
          Commercially Available Antibodies
           
          Other Information
          Relationship to Other Genes
          Source for database identify of

          Source for identity of: bin3 CG8276

          (FlyBase, 1996-)
          Source for database merge of

          Source for merge of: bin3 l(2)SH1014

          (FlyBase, 1996-)
          Additional comments

          "bin3" may correspond to "Scim20". Sequence analysis off ends of P{SUPor-P} in Scim insertion mutant places "Scim20" near/in "Pld" or "bin3".

          (Dobie and Karpen, 2001.4.18)

          Source for identity of bin3 CG8276 was sequence comparison ( date:000414 ).

          (FlyBase, 1996-)
          Other Comments

          Gene expression is increased in response to the presence of two copies of Scer\GAL4hs.PB.

          (Liu and Lehmann, 2008)

          4 alleles of l(2)SH1014 recovered in a P-insertion screen.

          (Oh et al., 2003)

          Identification: Interacts with bcd protein bound to DNA in a modified yeast two-hybrid screen.

          (Zhu and Hanes, 1998)
          Origin and Etymology
          Discoverer
          Etymology
          Identification
          External Crossreferences and Linkouts ( 70 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
          iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          Linkouts
          DroID - A comprehensive database of gene and protein interactions.
          MIST (protein-protein) - An integrated Molecular Interaction Database
          Synonyms and Secondary IDs (10)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          References (70)