FlyBase Gene Report: Dmel\bin3

S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it (Probable). Required for dorso-ventral patterning in oogenesis and for anterior-posterior pattern formation during embryogenesis, possibly by binding and stabilizing 7SK RNA, thereby promoting formation of a repressive RNA-protein complex.

(UniProt, Q7K480)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the GBrowse view of Dmel\bin3 or the JBrowse view of Dmel\bin3 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 6.02

Sequence Ontology: Class of Gene

gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

bin3-RA

FBtr0085993

NM_165468

5606

1367

bin3-RB

FBtr0085992

NM_078902

4760

1367

bin3-RC

FBtr0336519

NM_001273795

4718

1367

bin3-RD

FBtr0346718

NM_001316407

5616

1367

Additional Transcript Data and Comments

Reported size (kB)

4.588 (compiled cDNA)

(Zhu and Hanes, 2000)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

bin3-PA

FBpp0085337

146.2

1367

9.20

NP_724468

AAF57267

bin3-PB

FBpp0085336

146.2

1367

9.20

NP_523626

AAM68350

bin3-PC

FBpp0307591

146.2

1367

9.20

NP_001260724

AGB93258

bin3-PD

FBpp0312329

146.2

1367

9.20

NP_001303336

ALI30166

Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

1367 aa isoforms: bin3-PA, bin3-PB, bin3-PC, bin3-PD

Additional Polypeptide Data and Comments

Reported size (kDa)

1368 (aa); 146 (kD predicted)

(Zhu and Hanes, 2000)

Comments

External Data

Subunit Structure (UniProtKB)

Interacts with bicoid/bcd.

(UniProt, Q7K480)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bin3 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Linkouts

Gene Ontology (12 terms)

Molecular Function (6 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

protein binding

inferred from physical interaction with UniProtKB:P09081

(assigned by UniProt )

(Zhu and Hanes, 2000)

RNA polymerase II transcription factor binding

inferred from physical interaction with FLYBASE:bcd; FB:FBgn0000166

(Zhu and Hanes, 2000)

snRNA binding

inferred from direct assay

(Singh et al., 2011)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

methyltransferase activity

inferred from sequence or structural similarity with SGD:S000000238

(Zhu and Hanes, 2000)

O-methyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN000267975

(assigned by GO_Central )

(Gaudet et al., 2011)

RNA methyltransferase activity

inferred from biological aspect of ancestor with PANTHER:PTN000267975

(assigned by GO_Central )

(Gaudet et al., 2011)

snRNA binding

inferred from biological aspect of ancestor with PANTHER:PTN000267972

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (5 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

developmental process

inferred from mutant phenotype

(assigned by UniProt )

(Zhu and Hanes, 2000)

heterochromatin organization involved in chromatin silencing

inferred from mutant phenotype

(Swenson et al., 2016)

negative regulation of translation

inferred from mutant phenotype

(Singh et al., 2011)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

methylation

inferred from sequence or structural similarity with SGD:S000000238

(Zhu and Hanes, 2000)

snRNA modification

inferred from biological aspect of ancestor with PANTHER:PTN000267972

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

nucleus

inferred from direct assay

(Swenson et al., 2016)

Terms Based on Predictions or Assertions (0 terms)

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

anterior endoderm anlage

(Fisher et al., 2012)

foregut anlage

(Fisher et al., 2012)

head mesoderm

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 9 -- 10

anterior endoderm

(Fisher et al., 2012)

foregut primordium

(Fisher et al., 2012)

head mesoderm

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

posterior endoderm

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic brain

(Fisher et al., 2012)

organism | faint | ubiquitous

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

ventral nerve cord

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 9

Comment: reference states 0-4 hr AEL

(Zhu and Hanes, 2000)

organism | ubiquitous

(Zhu and Hanes, 2000)

Additional Descriptive Data

Northern blot analysis indicates that bin3 transcripts are most abundant in 0-2hr embryos, are at lower levels in 2-4hr embryos and drop dramatically in 4-24hr embryos. In situ hybridization shows that bin3 transcripts are distributed throughout the early embryo and in unfertilized eggs.

(Zhu and Hanes, 2000)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

nucleus

inferred from direct assay

(Swenson et al., 2016)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\bin3 in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\bin3

View exonic expression by tissue for Dmel\bin3

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0263144

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8276

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs and Phenotypes

Classical and Insertion Alleles ( 55 )

For All Classical and Insertion Alleles Show

Allele of bin3

Class

Mutagen

Associated Insertion

Stocks

Known lesion

bin3^e02231

piggyBac activity

PBac{RB}bin3^e02231

Yes

bin3^EY11308

P-element activity

P{EPgy2}bin3^EY11308

Yes

bin3^KG00599

P-element activity

P{SUPor-P}bin3^KG00599

Yes

bin3^KG03313

P-element activity

P{SUPor-P}bin3^KG03313

Yes

bin3^MI00156

Mi{MIC}bin3^MI00156

Yes

bin3^{MI08045-TG4.0}

phiC31 integrase

Mi{Trojan-GAL4.0}bin3^{MI08045-TG4.0}

Yes

bin3^BG01416

P{GT1}bin3^BG01416

Yes

bin3^d01198

P-element activity

P{XP}bin3^d01198

Yes

bin3^SH1014

P-element activity

Yes

Yes

Yes

Yes

Yes

Yes

piggyBac activity

PBac{IT.GAL4}bin3^0733-G4

Yes

bin3^1248-G4

piggyBac activity

PBac{IT.GAL4}bin3^1248-G4

Yes

bin3^BG00778

P-element activity

P{GT1}bin3^BG00778

Yes

bin3^c03082

piggyBac activity

PBac{PB}bin3^c03082

Yes

bin3^c03245

piggyBac activity

Yes

Yes

piggyBac activity

Yes

Yes

P-element activity

P{XP}bin3^d01219

Yes

bin3^d03755

P-element activity

P{XP}bin3^d03755

Yes

bin3^e02113

piggyBac activity

PBac{RB}bin3^e02113

Yes

bin3^e03062

piggyBac activity

PBac{RB}bin3^e03062

Yes

bin3^EY09582

P-element activity

P{EPgy2}bin3^EY09582

Yes

bin3^EY22780

P-element activity

P{EPgy2}bin3^EY22780

Yes

bin3^f02442

piggyBac activity

PBac{WH}bin3^f02442

Yes

bin3^f06612

piggyBac activity

Yes

Yes

P-element activity

P{SUPor-P}bin3^KG00254

Yes

bin3^KG08743

P{SUPor-P}bin3^KG08743

Yes

Yes

Yes

Yes

Yes

Yes

Yes

P-element activity

P{ST.lexA::HG}bin3^TD-7

Yes

bin3^2-7

FLPase

Yes

bin3^4-7

FLPase

Yes

bin3^BG01137

P{GT1}bin3^BG01137

bin3^d01159

P-element activity

Yes

Yes

P-element activity

Yes

Yes

P-element activity

P{XP}bin3^d10586

Yes

bin3^e04230

piggyBac activity

PBac{RB}bin3^e04230

Yes

bin3^f00149

piggyBac activity

PBac{WH}bin3^f00149

Yes

bin3^f05609

piggyBac activity

PBac{WH}bin3^f05609

Yes

bin3^f05633

piggyBac activity

Yes

Yes

Yes

Other relevant insertions

Transgenic Constructs ( 7 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of bin3

Allele of bin3

Mutagen

Associated Transgenic Construct

Stocks

in vitro construct - regulatory fusion

M{Hsp83-bin3.S}

bin3^NIG.8276R

P{NIG.8276R}

Transgenic constructs containing regulatory region of bin3

Deletions and Duplications ( 0 )

Summary of Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal (with Df(2R)BSC313)

bin3^{MI08045-TG4.0}

lethal | recessive

bin3^SH1014

lethal - all die before end of embryonic stage | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

bin3^EY11308

lethal - all die before end of embryonic stage | maternal effect (with bin3^2-7)

bin3^4-7

lethal - all die before end of embryonic stage | maternal effect (with bin3^4-7)

bin3^2-7

lethal - all die before end of embryonic stage | maternal effect (with Df(2R)Drl^rv25)

bin3^KG00599

viable

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

bin3^GD13872

viable, with Scer\GAL4^Mef2.PR

bin3^GD13872

viable, with Scer\GAL4^pnr-MD237

bin3^GD13872

viable, with Scer\GAL4^tin.CΔ4

bin3^GD13872

Sterility

Allele

fertile

Other Phenotypes

Allele

sleep defective | adult stage

bin3^BG01416

smell perception defective

bin3^BG01416

some die during embryonic stage | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

bin3^EY11308

some die during embryonic stage | maternal effect (with bin3^2-7)

bin3^4-7

some die during embryonic stage | maternal effect (with bin3^4-7)

bin3^2-7

some die during embryonic stage | maternal effect (with Df(2R)Drl^rv25)

bin3^KG00599

suppressor of variegation, with P{SUPor-P}KV00108

bin3^MI00156

visible, with Scer\GAL4^pnr-MD237

bin3^GD13872

Phenotype manifest in

Allele

cephalopharyngeal skeleton (with bin3^2-7)

bin3^4-7

cephalopharyngeal skeleton (with bin3^4-7)

bin3^2-7

embryonic head | maternal effect, with Scer\GAL4^{VP16.mat.αTub67C}

bin3^EY11308

mesothoracic tergum, with Scer\GAL4^pnr-MD237

bin3^GD13872

ovariole

tormogen cell, with Scer\GAL4^pnr-MD237

bin3^GD13872

Orthologs

Downloads

Download All DIOPT Orthologs

Download All OrthoDB Orthologs

Human Orthologs (via DIOPT v7.1)

Homo sapiens (Human) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Hsap\MEPCE

11 of 15

Yes

Hsap\BCDIN3D

1 of 15

Model Organism Orthologs (via DIOPT v7.1)

Mus musculus (laboratory mouse) (2)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Mmus\Mepce

9 of 15

Yes

Mmus\Bcdin3d

1 of 15

Rattus norvegicus (Norway rat) (2)

Rnor\LOC100910540

6 of 13

Yes

Rnor\Mepce

4 of 13

Yes

Xenopus tropicalis (Western clawed frog) (0)

No orthologs reported.

Danio rerio (Zebrafish) (2)

Drer\mepce

9 of 15

Yes

Drer\si:ch1073-157b13.1

8 of 15

Yes

Caenorhabditis elegans (Nematode, roundworm) (2)

Cele\Y17G7B.18

7 of 15

Yes

Cele\Y18D10A.21

1 of 15

Yes

Arabidopsis thaliana (thale-cress) (1)

Atha\AT5G51130

4 of 9

Yes

Saccharomyces cerevisiae (Brewer's yeast) (0)

No orthologs reported.

Schizosaccharomyces pombe (Fission yeast) (1)

Spom\SPBC2A9.10

5 of 12

Yes

Orthologs in Drosophila Species (via OrthoDB v9.1) ( EOG091901T4 )

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Dmel\bin3

Drosophila suzukii

Spotted wing Drosophila

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA26118

Drosophila pseudoobscura pseudoobscura

Dpse\GA20948

Drosophila persimilis

Dper\GL20337

Drosophila willistoni

Dwil\GK19498

Drosophila virilis

Dvir\GJ21451

Drosophila mojavensis

Dmoj\GI18374

Drosophila grimshawi

Dgri\GH20938

Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091503NY )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Musca domestica

House fly

Mdoa\17019869

Glossina morsitans

Tsetse fly

Gmor\GMOY010300

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_09385

Lucilia cuprina

Australian sheep blowfly

Lcup\FF38_09391

Mayetiola destructor

Hessian fly

Mdes\Mdes011093

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL003540

Anopheles darlingi

American malaria mosquito

Adar\ADAC005797

Anopheles gambiae

Malaria mosquito

Agam\AGAP012087

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ006467

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ000796

Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W03GK )

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Bombyx mori

Silkmoth

Bmor\BGIBMGA006788

Danaus plexippus

Monarch butterfly

Dple\DPOGS213805-PA

Heliconius melpomene

Postman butterfly

Hmel\HMEL014722

Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( None identified )

No non-Arthropod Metazoa orthologies identified

Human Disease Model Data

FlyBase Human Disease Model Reports

Alleles Reported to Model Human Disease (Disease Ontology)

Download

Models ( 0 )

Allele

Disease

Evidence

References

Interactions ( 1 )

Allele

Disease

Interaction

References

bin3^unspecified

exacerbates viral infectious disease

modeled by EBV\BRLF1^GMR.PA

(Adamson and Lajeunesse, 2012)

exacerbates infectious mononucleosis

modeled by EBV\BRLF1^GMR.PA

(Adamson and Lajeunesse, 2012)

exacerbates Epstein-Barr virus hepatitis

modeled by EBV\BRLF1^GMR.PA

(Adamson and Lajeunesse, 2012)

Comments ( 0 )

Human Orthologs (via DIOPT v7.1)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

Complementation?

Transgene?

MEPCE; methylphosphate capping enzyme

11 of 15

611478

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please look at the Interaction Group reports for full details of the physical interactions

protein-protein

Interacting group

Assay

References

bin3 - CG14074

two hybrid

(Hu et al., 2017.6.13)

bin3 - CG2017

two hybrid

(Hu et al., 2017.6.13)

bin3 - CG44250

two hybrid

(Hu et al., 2017.6.13)

bin3 - CG7824

two hybrid

(Hu et al., 2017.6.13)

bin3 - CG9467

two hybrid

(Hu et al., 2017.6.13)

bin3 - Lim1

two hybrid

(Hu et al., 2017.6.13)

bin3 - bcd

pull down, autoradiography, two hybrid

(Zhu and Hanes, 2000)

RNA-protein

Interacting group

Assay

References

bin3 - snRNA:7SK

anti tag coimmunoprecipitation, quantitative reverse transcription pcr

(Singh et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

bin3

enhanceable

bcd

(Singh et al., 2011)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Subunit Structure (UniProtKB)

Interacts with bicoid/bcd.

(UniProt, Q7K480 )

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0263144

Pathways

Gene Group - Pathway Membership (FlyBase)

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

2-55

Cytogenetic map

42A13-42A13

Sequence location

2R:6,214,568..6,240,602 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

42A13-42A13

Limits computationally determined from genome sequence between P{lacW}l(2)k09848^k09848&P{EP}EP407 and P{lacW}geminin^k14019&P{PZ}Adf1⁰¹³⁴⁹; Left limit from in situ hybridisation (FBrf0157097) Right limit from in situ hybridisation (FBrf0157097)

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

42A12-42A13

(Oh et al., 2003)

42A16-42B2

(Zhu, 1998.10.6)

42B-42B

(determined by in situ hybridisation)

(Zhu and Hanes, 2000)

Experimentally Determined Recombination Data

Location

2-55

(FlyBase, 2016)

2-55.8

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (41)

d01219

d03755

c03245

c04608

c05366

e02113

e02231

e03062

f02442

f06612

v330436

v101090

More stocks available...

Genomic Clones (22)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (50)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequences

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0263144

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

RNAi and Array Information

Linkouts

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35552

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Singh et al., 2011)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: bin3 CG8276

(FlyBase, 1996-)

Source for database merge of

Source for merge of: bin3 l(2)SH1014

(FlyBase, 1996-)

Additional comments

"bin3" may correspond to "Scim20". Sequence analysis off ends of P{SUPor-P} in Scim insertion mutant places "Scim20" near/in "Pld" or "bin3".

(Dobie and Karpen, 2001.4.18)

Source for identity of bin3 CG8276 was sequence comparison ( date:000414 ).

(FlyBase, 1996-)

Other Comments

Gene expression is increased in response to the presence of two copies of Scer\GAL4^hs.PB.

(Liu and Lehmann, 2008)

4 alleles of l(2)SH1014 recovered in a P-insertion screen.

(Oh et al., 2003)

Identification: Interacts with bcd protein bound to DNA in a modified yeast two-hybrid screen.

(Zhu and Hanes, 1998)

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 69 )

Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

35552

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q7K480

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

E2QC61

Other crossreferences

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0263144

InterPro - A database of protein families, domains and functional sites

Linkouts

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center cDNA clones

FBgn0263144

DroID - A comprehensive database of gene and protein interactions.

FBgn0263144

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG8276

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

35552

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC011992

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG8276

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

Bin3

(Singh et al., 2011, Zhu and Hanes, 1998)

CG8276

(Meadows, 2017.9.14, Christis and Munro, 2012, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Katz et al., 2003, Dobie and Karpen, 2001.4.18, Zhu, 2000.10.31)

bin3

(Lee et al., 2018, Sun et al., 2018, Hu et al., 2017.6.13, Lobell et al., 2017, Clandinin and Owens, 2016-, Gene Disruption Project members, 2016-, Kockel et al., 2016, Lee et al., 2016, Liu and Secombe, 2015, Brown et al., 2013, Kwon et al., 2013, Lavagnino et al., 2013, Wilson et al., 2013, Japanese National Institute of Genetics, 2012.5.21, Nguyen et al., 2012, Ayroles et al., 2009, Harbison et al., 2009, Liu and Lehmann, 2008, LaLonde et al., 2006)

l(2)SH1014

l(2)SH2 1014

(Oh et al., 2002.3.24)

Name Synonyms

Bicoid interacting protein 3

(Zhu and Hanes, 1998)

Bicoid-interacting protein 3

(Adamson and Lajeunesse, 2012)

bicoid interacting protein 3

(Adamson and Lajeunesse, 2012)

bicoid-interacting protein 3

(Harbison et al., 2009, Tadros et al., 2007, LaLonde et al., 2006, Sambandan et al., 2006, Zhu, 1998.10.6)

lethal (2) SH1014

Secondary FlyBase IDs

FBgn0033073
FBgn0024490
FBgn0065556

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

References (62)

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