FB2020_06, released Dec 22, 2020

Gene: Dmel\SP1029

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General Information
Symbol
Dmel\SP1029
Species
D. melanogaster
Name
SP1029
Annotation Symbol
CG11956
Feature Type
protein_coding_gene
FlyBase ID
FBgn0263236
Gene Model Status
Current
Stock Availability
6 publicly available
Gene Snapshot
Contributions welcome
Other Summaries
Key Links
Genomic Location
Cytogenetic map
99A6-99A5
Sequence location
3R:29,244,961..29,250,451 [-]
Recombination map

3-98

RefSeq locus
NT_033777 REGION:29244961..29250451
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (6 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables metalloaminopeptidase activity
inferred from biological aspect of ancestor with PANTHER:PTN000164250
(assigned by GO_Central )
(Gaudet et al., 2011)
enables peptide binding
inferred from biological aspect of ancestor with PANTHER:PTN000164250
(assigned by GO_Central )
(Gaudet et al., 2011)
enables zinc ion binding
inferred from biological aspect of ancestor with PANTHER:PTN000164250
(assigned by GO_Central )
(Gaudet et al., 2011)
Biological Process (2 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (2 terms)
CV Term
Evidence
References
involved_in peptide catabolic process
inferred from biological aspect of ancestor with PANTHER:PTN000164250
(assigned by GO_Central )
(Gaudet et al., 2011)
involved_in proteolysis
inferred from biological aspect of ancestor with PANTHER:PTN000164251
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
located_in cytoplasm
inferred from biological aspect of ancestor with PANTHER:PTN000164250
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Group (FlyBase)
M1 METALLOPEPTIDASES -
M1 metallopeptidases belong to MEROPS family M1. All members of the family act on the N-terminus of polypeptides, many of them being aminopeptidases. The family also contains pyroglutamyl-peptidase II, an omega peptidase that releases pyroglutamate from thyrotropin-releasing hormone, and some dipeptidases. (Adapted from FBrf0239469.)
Gene Model and Products
Number of Transcripts
5
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\SP1029 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Gene model reviewed during 5.47

Low-frequency RNA-Seq exon junction(s) not annotated.

Annotated transcripts do not represent all supported alternative splices within 5' UTR.

Gene model reviewed during 5.55

Sequence Ontology: Class of Gene
gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
SP1029-RA
FBtr0085398
NM_144361
3026
932
SP1029-RB
FBtr0085399
NM_170405
3321
932
SP1029-RC
FBtr0085400
NM_170406
3158
932
SP1029-RD
FBtr0334868
NM_001276136
3198
932
SP1029-RE
FBtr0345203
NM_001300651
2981
932
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
SP1029-PA
FBpp0084767
108.0
932
6.57
NP_652618
AAF56884
SP1029-PB
FBpp0084768
108.0
932
6.57
NP_733284
AAG22174
SP1029-PC
FBpp0084769
108.0
932
6.57
NP_733285
AAN14169
SP1029-PD
FBpp0306891
108.0
932
6.57
NP_001263065
AGB96445
SP1029-PE
FBpp0311398
108.0
932
6.57
NP_001287580
AHN57579
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

932 aa isoforms: SP1029-PA, SP1029-PB, SP1029-PC, SP1029-PD, SP1029-PE
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\SP1029 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\SP1029 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, and Transgenic Constructs
Classical and Insertion Alleles ( 2 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 6 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of SP1029
Transgenic constructs containing regulatory region of SP1029
Deletions and Duplications ( 1 )
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
partially lethal - majority die, with Scer\GAL4Act5C.PU
viable, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
viable, with Scer\GAL4tin.CΔ4
Other Phenotypes
Allele
visible, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
chaeta | supernumerary, with Scer\GAL4pnr-MD237
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (16)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\ANPEP
8 of 15
Yes
No
Hsap\ERAP1
5 of 15
No
Yes
Hsap\ERAP2
5 of 15
No
Yes
Hsap\LNPEP
5 of 15
No
Yes
Hsap\LVRN
5 of 15
No
Yes
Hsap\ENPEP
4 of 15
No
No
1  
Hsap\NPEPPS
4 of 15
No
No
Hsap\TRHDE
3 of 15
No
No
Hsap\RNPEP
2 of 15
No
Yes
Hsap\RNPEPL1
2 of 15
No
Yes
Hsap\ANTXR2
1 of 15
No
Yes
Hsap\AOPEP
1 of 15
No
No
Hsap\LOC440434
1 of 15
No
No
Hsap\LOC101929950
1 of 15
No
Yes
Hsap\LTA4H
1 of 15
No
No
Hsap\MIR24-1
1 of 15
No
Yes
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (11)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Anpep
8 of 15
Yes
No
Mmus\Lvrn
6 of 15
No
Yes
Mmus\Erap1
5 of 15
No
Yes
Mmus\Lnpep
5 of 15
No
Yes
Mmus\Enpep
4 of 15
No
No
Mmus\Npepps
4 of 15
No
No
Mmus\Trhde
3 of 15
No
No
Mmus\Aopep
2 of 15
No
Yes
Mmus\Rnpepl1
2 of 15
No
Yes
Mmus\Rnpep
2 of 15
No
Yes
Mmus\Lta4h
1 of 15
No
No
Rattus norvegicus (Norway rat) (12)
Rnor\Anpep
7 of 13
Yes
No
Rnor\Erap1
5 of 13
No
Yes
Rnor\Lnpep
5 of 13
No
Yes
Rnor\Lvrn
4 of 13
No
No
Rnor\Npepps
4 of 13
No
No
Rnor\Enpep
3 of 13
No
No
Rnor\Trhde
3 of 13
No
No
Rnor\Npepo
2 of 13
No
Yes
Rnor\Rnpep
2 of 13
No
Yes
Rnor\LOC100910501
1 of 13
No
Yes
Rnor\LOC108348118
1 of 13
No
Yes
Rnor\Lta4h
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (10)
Xtro\erap1
5 of 12
Yes
Yes
Xtro\lnpep
5 of 12
Yes
Yes
Xtro\anpep
4 of 12
No
Yes
Xtro\lvrn
4 of 12
No
Yes
Xtro\npepps
4 of 12
No
No
Xtro\enpep
3 of 12
No
No
Xtro\c9orf3
2 of 12
No
Yes
Xtro\rnpep
2 of 12
No
Yes
Xtro\lta4h
1 of 12
No
No
Xtro\trhde
1 of 12
No
Yes
Danio rerio (Zebrafish) (17)
Drer\si:ch211-106j24.1
7 of 15
Yes
No
Drer\anpepb
5 of 15
No
No
Drer\erap1a
5 of 15
No
Yes
Drer\erap1b
5 of 15
No
Yes
Drer\erap2
5 of 15
No
Yes
Drer\lnpep
5 of 15
No
Yes
Drer\si:ch211-276a23.5
5 of 15
No
No
Drer\anpepa
4 of 15
No
No
Drer\LOC100004744
4 of 15
No
No
Drer\npepps
4 of 15
No
No
Drer\enpep
3 of 15
No
No
Drer\trhde.1
3 of 15
No
No
Drer\trhde.2
3 of 15
No
No
Drer\rnpep
2 of 15
No
Yes
Drer\rnpepl1
2 of 15
No
Yes
Drer\aopep
1 of 15
No
No
Drer\lta4h
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (15)
Cele\anp-1
6 of 15
Yes
No
Cele\F49B2.6
6 of 15
Yes
No
Cele\pam-1
4 of 15
No
No
Cele\R03G8.4
4 of 15
No
Yes
Cele\R03G8.6
4 of 15
No
No
Cele\T16G12.1
4 of 15
No
Yes
Cele\Y42A5A.1
4 of 15
No
No
Cele\T12E12.6
3 of 15
No
No
Cele\Y67D8C.9
3 of 15
No
No
Cele\AC3.5
2 of 15
No
No
Cele\Y53F4B.20
2 of 15
No
Yes
Cele\ltah-1.1
1 of 15
No
No
Cele\ltah-1.2
1 of 15
No
No
Cele\mnp-1
1 of 15
No
No
Cele\VB0395L.1
1 of 15
No
Yes
Arabidopsis thaliana (thale-cress) (2)
Atha\APM1
2 of 9
Yes
No
Atha\AT1G63770
1 of 9
No
Yes
Saccharomyces cerevisiae (Brewer's yeast) (4)
Scer\AAP1
3 of 15
Yes
No
Scer\APE2
3 of 15
Yes
No
Scer\TMA108
2 of 15
No
No
Scer\LAP2
1 of 15
No
No
Schizosaccharomyces pombe (Fission yeast) (1)
Spom\ape2
2 of 12
Yes
No
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG091901P9 )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00013560
Drosophila suzukii
Spotted wing Drosophila
Dsuz\DS10_00013027
Drosophila simulans
Dsim\GD17853
Drosophila sechellia
Dsec\GM12248
Drosophila erecta
Dere\GG12022
Drosophila yakuba
Dyak\GE10459
Drosophila ananassae
Dana\GF22895
Drosophila pseudoobscura pseudoobscura
Dpse\GA26842
Drosophila persimilis
Dper\GL13602
Drosophila willistoni
Dwil\GK22491
Drosophila virilis
Dvir\GJ14226
Drosophila mojavensis
Dmoj\GI22347
Drosophila grimshawi
Dgri\GH14003
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG091500O0 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17020352
Musca domestica
House fly
Mdoa\17024314
Musca domestica
House fly
Mdoa\17020353
Musca domestica
House fly
Mdoa\17018543
Glossina morsitans
Tsetse fly
Gmor\GMOY000698
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_14213
Mayetiola destructor
Hessian fly
Mdes\Mdes011987
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL011292
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL012217
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL011291
Anopheles darlingi
American malaria mosquito
Adar\ADAC004413
Anopheles gambiae
Malaria mosquito
Agam\AGAP000885
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ014660
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W00P0 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA008063
Bombyx mori
Silkmoth
Bmor\BGIBMGA010679
Bombyx mori
Silkmoth
Bmor\BGIBMGA008062
Bombyx mori
Silkmoth
Bmor\BGIBMGA008060
Bombyx mori
Silkmoth
Bmor\BGIBMGA008061
Bombyx mori
Silkmoth
Bmor\BGIBMGA010763
Bombyx mori
Silkmoth
Bmor\BGIBMGA008059
Bombyx mori
Silkmoth
Bmor\BGIBMGA008017
Danaus plexippus
Monarch butterfly
Dple\DPOGS208533-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS200548-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS200549-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS209835-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS209837-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS209838-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS209792-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS213708-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS209836-PA
Danaus plexippus
Monarch butterfly
Dple\DPOGS209834-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL016873
Heliconius melpomene
Postman butterfly
Hmel\HMEL008410
Heliconius melpomene
Postman butterfly
Hmel\HMEL008406
Heliconius melpomene
Postman butterfly
Hmel\HMEL004351
Heliconius melpomene
Postman butterfly
Hmel\HMEL015730
Heliconius melpomene
Postman butterfly
Hmel\HMEL008411
Heliconius melpomene
Postman butterfly
Hmel\HMEL004822
Heliconius melpomene
Postman butterfly
Hmel\HMEL008412
Heliconius melpomene
Postman butterfly
Hmel\HMEL008414
Heliconius melpomene
Postman butterfly
Hmel\HMEL008407
Heliconius melpomene
Postman butterfly
Hmel\HMEL008408
Apis florea
Little honeybee
Aflo\2193038292
Apis florea
Little honeybee
Aflo\2201295732
Apis florea
Little honeybee
Aflo\2729525796
Apis florea
Little honeybee
Aflo\2193035012
Apis mellifera
Western honey bee
Amel\GB49578
Apis mellifera
Western honey bee
Amel\GB42427
Apis mellifera
Western honey bee
Amel\LOC412808
Apis mellifera
Western honey bee
Amel\GB51237
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP12610
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP18041
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP12531
Bombus impatiens
Common eastern bumble bee
Bimp\BIMP25163
Bombus terrestris
Buff-tailed bumblebee
Bter\15202292
Bombus terrestris
Buff-tailed bumblebee
Bter\15203687
Bombus terrestris
Buff-tailed bumblebee
Bter\15216045
Bombus terrestris
Buff-tailed bumblebee
Bter\15203780
Bombus terrestris
Buff-tailed bumblebee
Bter\15216138
Linepithema humile
Argentine ant
Lhum\LH22816
Linepithema humile
Argentine ant
Lhum\LH22817
Linepithema humile
Argentine ant
Lhum\LH22821
Linepithema humile
Argentine ant
Lhum\LH22823
Linepithema humile
Argentine ant
Lhum\LH14564
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0022fe
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002300
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:00163e
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0022ff
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:0011e4
Megachile rotundata
Alfalfa leafcutting bee
Mrot\MROTU:002301
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001187
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG011290
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG001189
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005034
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG010684
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG012478
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG005036
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007961
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08069
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08068
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_00326
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_03918
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_08070
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_10931
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_09622
Tribolium castaneum
Red flour beetle
Tcas\TC030950
Tribolium castaneum
Red flour beetle
Tcas\TC001262
Tribolium castaneum
Red flour beetle
Tcas\TC001259
Tribolium castaneum
Red flour beetle
Tcas\TC004952
Tribolium castaneum
Red flour beetle
Tcas\TC001260
Tribolium castaneum
Red flour beetle
Tcas\TC004557
Tribolium castaneum
Red flour beetle
Tcas\TC001261
Tribolium castaneum
Red flour beetle
Tcas\TC004830
Pediculus humanus
Human body louse
Phum\PHUM411940
Pediculus humanus
Human body louse
Phum\PHUM412200
Pediculus humanus
Human body louse
Phum\PHUM128360
Pediculus humanus
Human body louse
Phum\PHUM411950
Rhodnius prolixus
Kissing bug
Rpro\RPRC012350
Cimex lectularius
Bed bug
Clec\CLEC001792
Cimex lectularius
Bed bug
Clec\CLEC004703
Cimex lectularius
Bed bug
Clec\CLEC010110
Cimex lectularius
Bed bug
Clec\CLEC004704
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI010198
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI34486
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001389
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI005199
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI000526
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI41611
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001092
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI067721
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI060578
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI52349
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI22605
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI008967
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003165
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002583
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006655
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI089346
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI071951
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI33244
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI002831
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI067691
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI001203
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI003280
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI22813
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI000001
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI006675
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI43770
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI080787
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI000734
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI005810
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI060701
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_01238
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_09632
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_09620
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_11243
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_15105
Zootermopsis nevadensis
Nevada dampwood termite
Znev\Znev_14627
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( EOG090X02W0 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strigamia maritima
European centipede
Smar\SMAR005107
Strigamia maritima
European centipede
Smar\SMAR005775
Strigamia maritima
European centipede
Smar\SMAR013689
Strigamia maritima
European centipede
Smar\SMAR007021
Ixodes scapularis
Black-legged tick
Isca\ISCW006685
Ixodes scapularis
Black-legged tick
Isca\ISCW005386
Stegodyphus mimosarum
African social velvet spider
Smim\KFM56852.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM56599.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM75424.1
Stegodyphus mimosarum
African social velvet spider
Smim\KFM69000.1
Tetranychus urticae
Two-spotted spider mite
Turt\tetur21g03280
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_315872
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_304409
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_115736
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_329565
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_196131
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_64107
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_331359
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_203789
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_203795
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_302210
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_302859
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_203797
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_317254
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_61964
Daphnia pulex
Water flea
Dpux\DAPPUDRAFT_218787
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G01GH )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Npepps
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn7_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Anpep_1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn7
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Maapd
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Enpep_2
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn5
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn5a
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Ttrhde
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn1
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn4
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn6
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Anpep
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Apn5b
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000003909
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000004939
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000006862
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000022842
Gallus gallus
Domestic chicken
Ggal\NPEPPS
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000002318
Gallus gallus
Domestic chicken
Ggal\ERAP1
Gallus gallus
Domestic chicken
Ggal\TRHDE
Gallus gallus
Domestic chicken
Ggal\LNPEP
Gallus gallus
Domestic chicken
Ggal\ENPEP
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000027501
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (22)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CG31445
8 of 10
superdeath
7 of 10
CG8773
6 of 10
CG8774
6 of 10
CG11951
6 of 10
CG32473
6 of 10
CG3502
5 of 10
CG31233
5 of 10
CG31343
5 of 10
Psa
5 of 10
CG2111
4 of 10
CG5849
4 of 10
CG6071
4 of 10
CG7653
4 of 10
CG9806
4 of 10
CG31198
4 of 10
CG46339
4 of 10
CG4467
3 of 10
CG40470
3 of 10
CG42335
3 of 10
CG10602
2 of 10
CR31427
1 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    ANPEP; alanyl aminopeptidase, membrane
    8 of 15
    151530
        ERAP1; endoplasmic reticulum aminopeptidase 1
        5 of 15
        606832
            ERAP2; endoplasmic reticulum aminopeptidase 2
            5 of 15
            609497
                LNPEP; leucyl and cystinyl aminopeptidase
                5 of 15
                151300
                    LVRN; laeverin
                    5 of 15
                    610046
                        ENPEP; glutamyl aminopeptidase
                        4 of 15
                        138297
                             
                            NPEPPS; aminopeptidase puromycin sensitive
                            4 of 15
                            606793
                                TRHDE; thyrotropin releasing hormone degrading enzyme
                                3 of 15
                                606950
                                    Functional Complementation Data
                                    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                    Interactions
                                    Summary of Physical Interactions
                                    esyN Network Diagram
                                    Interactions Browser
                                    Summary of Genetic Interactions
                                    esyN Network Diagram
                                    Starting gene(s)
                                    Interaction type
                                    Interacting gene(s)
                                    Reference
                                    Starting gene(s)
                                    Interaction type
                                    Interacting gene(s)
                                    Reference
                                    External Data
                                    Linkouts
                                    DroID - A comprehensive database of gene and protein interactions.
                                    MIST (protein-protein) - An integrated Molecular Interaction Database
                                    Pathways
                                    Signaling Pathways (FlyBase)
                                    Metabolic Pathways
                                    External Data
                                    Linkouts
                                    KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                    Genomic Location and Detailed Mapping Data
                                    Chromosome (arm)
                                    3R
                                    Recombination map

                                    3-98

                                    Cytogenetic map
                                    99A6-99A5
                                    Sequence location
                                    3R:29,244,961..29,250,451 [-]
                                    FlyBase Computed Cytological Location
                                    Cytogenetic map
                                    Evidence for location
                                    99A6-99A5
                                    Left limit from molecular mapping relative to stg (FBrf0073015) Right limit from molecular mapping relative to stg (FBrf0073015); Limits computationally determined from genome sequence between P{PZ}l(3)0470804708 and P{PZ}l(3)0674306743
                                    Experimentally Determined Cytological Location
                                    Cytogenetic map
                                    Notes
                                    References
                                    99A5-99A6
                                    (Serano, 2000.2.4)
                                    99A-99A
                                    (Edgar et al., 1994)
                                    Experimentally Determined Recombination Data
                                    Location

                                    3-98

                                    (FlyBase, 2016)

                                    3-94.8

                                    (Comeron et al., 2012)
                                    Left of (cM)
                                    Right of (cM)
                                    Notes
                                    Stocks and Reagents
                                    Stocks (6)
                                    Genomic Clones (24)
                                    cDNA Clones (63)
                                     

                                    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                                    cDNA clones, fully sequenced
                                    BDGP DGC clones
                                    Other clones
                                    Drosophila Genomics Resource Center cDNA clones

                                    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                    cDNA Clones, End Sequenced (ESTs)
                                    BDGP DGC clones
                                    Other clones
                                    RNAi and Array Information
                                    Linkouts
                                    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                    Antibody Information
                                    Laboratory Generated Antibodies
                                     
                                    Commercially Available Antibodies
                                     
                                    Other Information
                                    Relationship to Other Genes
                                    Source for database identify of
                                    Source for database merge of

                                    Source for merge of: SP1029 CG11956

                                    (Bayraktaroglu, 2000.8.7)

                                    Source for merge of: SP1029 ptls

                                    (FlyBase, 1996-)
                                    Additional comments
                                    Other Comments

                                    Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days.

                                    (Claridge-Chang et al., 2001)

                                    Defined as a transcription unit immediately adjacent to the 3' end of stg.

                                    (Edgar et al., 1994)
                                    Origin and Etymology
                                    Discoverer
                                    Etymology
                                    Identification
                                    External Crossreferences and Linkouts ( 48 )
                                    Sequence Crossreferences
                                    NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                    RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                    UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                                    Other crossreferences
                                    BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
                                    Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                    Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                    Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                    GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                    iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                                    InterPro - A database of protein families, domains and functional sites
                                    KEGG Genes - Molecular building blocks of life in the genomic space.
                                    Linkouts
                                    DroID - A comprehensive database of gene and protein interactions.
                                    KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                    MIST (protein-protein) - An integrated Molecular Interaction Database
                                    Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.
                                    Synonyms and Secondary IDs (5)
                                    Datasets (0)
                                    Study focus (0)
                                    Experimental Role
                                    Project
                                    Project Type
                                    Title
                                    References (51)