a MAP4K3 that regulates TOR activity detected by phosphorylation of S6K and 4EBP - required for amino acids to stimulate TOR complex activity - binds physically to the Rag GTPases - promotes caspase-dependent apoptosis
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.50
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\hppy using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\hppy in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: hppy CG7097
Source for merge of CG7097 anon-WO0153538.68 was sequence comparison ( date:051113 ).
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
The gene is named "happyhour" because its mutation results in flies being able to imbibe significantly more alcohol than wild-type controls before succumbing to its sedating effects.